[The possibility of enamel remineralization in adults]. / Vozmozhnosti remineralizatsii émali zubov u vzroslykh.

The purpose of the study is comparative evaluation of modern mineralizing means and determine the effectiveness of dental caries prevention in adults. The study was conducted on 210 patients between the ages of 35 to 55 years old, divided into 6 equal groups with different means and modes of prevention (gel Tooth Mousse GC, Japan; gel Apaden-Pro Sangi, Japan; gel Fluokal Septodont, France). For dynamic monitoring and evaluating the effectiveness of prevention interventions used CPU index, OHI-S, the evaluation of cariesresistance by Nedoseko, acid biopsy of enamel. The most stable results after using gel Tooth Mousse; Apadent-Pro provides the fastest mineralization. Already after the first Apadent-Pro application was a high cariesresistance (Ca/P=1.80±0.41; p<0.01). While rubbing gel Tooth Mousse mineralization was growing gradually. In our view, it is appropriate to combine these medications: one or double rubbing gel Apadent-Pro combine with semi-annual course gel Tooth Mousse. Clinical data and laboratory studies on the effectiveness of the application of various means of preventing persons have senior age groups demonstrated that when personalized approach to the choice of the means of prevention and the multiplicity of their application It is possible to achieve increasing enamel cariesresistance and thus reduce the increase of caries in the population.

[Comparative in vitro evaluation of modern glass ionomer cements for adhesion strength and fluoride release].

The study proved similar adhesion strength and fluoride release level in aqueous extracts of glass ionomer cements Cemion (VladMiVa, Russia), Glassin Rest (Omega-Dent, Russia), Cemfil 10 (StomaDent, Russia) and Fuji VIII (GC Corporation, Japan). Despite of close concentrations of fluoride in glasses, the rate of fluoride release in water from calcium and calcium-barium glasses is much higher than that of strontium glasses.

[Influence of calcium and phosphate ions on the adsorption rate of alkaline phosphatase and some of serum proteins on the hydroxyapatite].

Calcium ions accelerate selective adsorption of AP on HAP and phosphate ions inhibit it. Since the biological function of AP is in the synthesis of phosphate ions from organic phosphates, enzyme activity contributes to its adsorption on mineralized tissues HAP, which can be associated with the peculiarities of the action of the enzyme adsorbed compared with dissolved. Apparently, the selective adsorption of enzymes and signaling molecules in the extracellular matrix to produce the microenvironment necessary for cell differentiation and function of tissue. Sorbate composition determines the type of cell differentiation, which, in turn, determines the properties of the synthesized matrix. Thereby circuiting occurs a feedback loop, to maintain homeostasis of tissues. These results can be used to develop a biomimetic material for medicine as well as the fabrication of multilayer coatings with desired properties by means of controlled speed by selectively depositing colloidal particles (nanoparticles). In the case of anisotropic particles the layers it is possible to obtain particles not only one type, but also with their desired orientation in each layer of particles by creating localized sorbent binding sites.

[Dynamics of formation of bone tissue in rats under the influence of new xenotransplantat "Norian"].

In experiments on rats CD comparative studies have been carried out which is the effect of osteoplastic material NORIAN CRS, the rate of bone regeneration after mandibular dental implants (titanium screw) and the combined effect of these processes NORIAN CRS protein and protein (Emdogein). Functionality and maturity of the newly formed bone tissue was evaluated by histological and biochemical methods. The results suggest that the use of osteoplastic material NORIAN CRS is the 120 days leading to almost complete regeneration of bone tissue. It was also found that the combined use of NORIAN CRS and protein Emdogein impractical because adding Emdogein not accelerate bone regenerative process, but in the early postoperative period may cause an inflammatory reaction.