RESUMEN
Purpose: The purpose of this study is to determine the relationships between foveal avascular zone (FAZ), foveal vascular density (FD) and GCC (ganglion cell complex) parameters in a healthy myopic population using optical coherence tomography angiography (angio-OCT). Patients and Methods: Three hundred and eighty-one eyes of 381 healthy participants were included into this study and assigned to three groups according to their spherical equivalent (SE) values and an additional progressive myopia group. One randomly chosen eye from each patient was analyzed. GCC mean thickness, focal loss of volume (FLV), global loss of volume (GLV), FAZ area, FAZ perimeter, and FD parameters were obtained with the RTVue AngioOCT device. Results: FAZ area and its perimeter were strongly correlated with the belonging spherical equivalent group (p = 0.0001, p = 0.0008 accordingly), being the largest in progressive myopia subgroup (mean size 0.42mm2). Other factors that were significantly higher in myopic eyes were FLV (p = 0.0023), GLV (p = 0.0020). There were no differences in FD between groups. In the myopic and progressive myopia groups, there was a significant relationship between FAZ area and FLV, GLV, and GCC thickness. We found that in myopic eyes with AXL exceeding 26.6 mm, FAZ becomes negatively correlated to mean GCC thickness. Conclusion: In myopia, compared to non-myopic groups, there is a greater loss of neural tissue represented by a thinner GCC layer, greater FLV and GLV parameters, and worse blood supply represented by a larger FAZ area. Eye axial length of 26.6 mm is a breaking point, where the negative FAZ area to GCC thickness relationship curve is getting significantly steeper.
RESUMEN
The asymmetric unit of the title compound, [Ag(C(10)H(9)N(2))(2)]CF(3)SO(3) or [Ag(dpa)(2)]OTf (dpa is di-2-pyridylamine and OTf is the trifluoromethanesulfonate anion), contains two [Ag(dpa)(2)](+) coordination cations and two OTf anions. The coordination geometry of the Ag(I) atom is intermediate between square-planar and tetrahedral, with similar deformations at the two symmetry-independent metal centres. The dpa ligands coordinate in a bidentate chelating mode. The OTf anions are in the outer coordination sphere and bridge the coordination cations via N-H...O interactions to form two symmetry-independent hydrogen-bonded chains. The [Ag(dpa)(2)](+) cations are arranged via interactions involving the aromatic groups into a pseudo-centrosymmetric three-dimensional framework with two types of channels, each confining congeners of one of the symmetry-independent anions. The most interesting feature of this structure is its bulk polarity resulting from an approximately parallel alignment of the anions in the channels.
