1.
J Clin Oncol
; 30(1): 114-5; author reply 114, 2012 Jan 01.
Artículo
en Inglés
| MEDLINE
| ID: mdl-22124105
2.
Anticancer Drugs
; 22 Suppl 2: S15-7, 2011 Jun.
Artículo
en Inglés
| MEDLINE
| ID: mdl-21768792
RESUMEN
Bevacizumab-containing treatment is one of the approved first-line options for the management of metastatic colorectal cancer (CRC). Carcino-embryonic antigen (CEA) is a reasonable tumour marker for monitoring the efficacy of treatment. We report here a case of a 58-year-old male patient with metastatic CRC. He received first-line chemotherapy consisting of the mFOLFOX6 regimen plus bevacizumab. Initially he had an increase in CEA after which the level reduced, suggesting the occurrence of a CEA flare. The patient experienced a good response to therapy. In recent literature, CEA flare was identified as a good predictor of response to first-line chemotherapy.