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Drug Dev Ind Pharm ; 36(1): 93-101, 2010 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-19656003

RESUMEN

BACKGROUND: It is well known that the Amazon region presents a huge biodiversity; therefore, countless natural resources are being employed in the production of phytocosmetics and phytomedicines. OBJECTIVE: The purpose of this work was to obtain emulsions produced with Buriti oil and non-ionic surfactants. METHODS: Two surfactant systems were employed (Steareth-2 associated to Ceteareth-5 and to Ceteareth-20) to produce the emulsions using phase diagram method. Emulsions were obtained by echo-planar imaging method at 75°C. Rheological behavior and zeta potential were evaluated, and accelerated stability tests were performed. RESULTS: All emulsions analyzed presented pseudoplastic behavior. Zeta potential values were obtained between -14.2 and -53.3 mV. The formulations did not show changes in either physical stability, pH, or rheological behavior after accelerated stability tests. Significant differences were observed only after temperature cycling test. CONCLUSION: Based on these results, the emulsions obtained could be considered as promising delivery systems.


Asunto(s)
Carotenoides/administración & dosificación , Sistemas de Liberación de Medicamentos , Aceites de Plantas/administración & dosificación , Tensoactivos/química , Carotenoides/química , Estabilidad de Medicamentos , Almacenaje de Medicamentos , Emulsiones , Concentración de Iones de Hidrógeno , Cristales Líquidos/química , Aceites de Plantas/química , Reología , Temperatura
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