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1.
Mymensingh Med J ; 29(1): 5-15, 2020 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-31915329

RESUMEN

Acute post-streptococcal glomerulonephritis (APSGN) is the commonest cause of acute glomerulonephritis (AGN), which usually present with gross hematuria, mild edema, oliguria, hypertension and varying degree of renal insufficiency. It is more common among the population of school going age where poverty, overcrowding and poor hygienic conditions are prevailing. This cross sectional observational study was aimed to know the socio-demographic variables, clinical profile and immediate outcome of AGN in hospitalized children and was conducted in the Pediatric department of Mymensingh Medical College Hospital (MMCH), Mymensingh, Bangladesh from November 2014 to April 2015. A detailed history was taken from the parents in each case with a written questionnaire. A written consent was also taken from the guardian of the including patients and also permission was taken from the ethical committee of MMCH. Thorough clinical examination and available relevant investigations were done in all patients. Progresses of the patient were monitored by daily clinical examinations and also by investigations. Data were analyzed by statistical package for social science (SPSS) windows version 18. Results were verified by doing standard test for significance. Among total 60 cases male was 58.3% & female was 41.7%. The common age group of presentation was between 7-12 years (73%), peak age of incidence was 7-9 years. Most of them came from low socioeconomic status (83.3%), 63.3% from rural area with average 5-6 member's family size. Most of the parents were illiterate. History of (H/O) skin infection was present in 35(58.3%) patients, 15(25%) had H/O sore throat, 15% did not give any H/O infection before presentation. Average duration of gap between infection and appearance of clinical feature was 7-14 days in 73.40%and 15-21 days was in 45.7% in case of sore throat & skin infection respectively. Almost all (95%) patients presented with puffiness of face, others presented with scanty micturition, gross hematuria, respiratory distress, fever, convulsion and altered sensorium. Edema (75%), hypertension (88.3%), pallor (38%), tachypnea (25%), tachycardia (26.7%) were the important clinical findings. Microscopic hematuria was present among 96.66% patients; low complement level was found in 85% cases. There is significant association between low socioeconomic statuses with more hospital stay. Only one patient died due to heart failure and 98.3% patient had complete recovery. Results of this study conclude that most of the patients came from rural illiterate family with low socioeconomic background. Skin infection is the commonest cause of acute glomerulonephritis. Edema, scanty micturation, hematuria and hypertension are the common mode of presentation. Heart failure and hypertensive encephalopathy are the common complication of AGN. Immediate prognosis of AGN was excellent.


Asunto(s)
Glomerulonefritis/diagnóstico , Tiempo de Internación/estadística & datos numéricos , Enfermedad Aguda , Bangladesh/epidemiología , Niño , Estudios Transversales , Femenino , Glomerulonefritis/epidemiología , Humanos , Incidencia , Masculino , Pediatría , Población Rural , Factores Socioeconómicos
2.
Heliyon ; 5(6): e01753, 2019 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-31198863

RESUMEN

Jute fabrics and unidirectional jute fiber reinforced polypropylene (PP) and linear low density polyethylene (LLDPE) based composites were prepared successfully by compression molding technique. The unidirectional jute fiber was treated with Reactive Orange HB® and Deep Blue LW® dye to investigate physico-mechanical properties. The Reactive Orange HB® treated composites showed relatively better mechanical properties than the Deep Blue LW® treated composites. The jute fiber-based composites showed higher mechanical properties than that of jute-based fabrics. The polypropylene-based composites showed better mechanical properties than that of LLDPE. The variations of mechanical properties were also observed. The highest mechanical properties were at -18 °C and lowest at 50 °C. Water absorbent, SEM and FT-IR analysis of the composite was also carried out.

3.
Sci Rep ; 7(1): 12494, 2017 10 02.
Artículo en Inglés | MEDLINE | ID: mdl-28970512

RESUMEN

Accumulated evidence suggests a physiological relationship between the transcription factor NRF3 (NFE2L3) and cancers. Under physiological conditions, NRF3 is repressed by its endoplasmic reticulum (ER) sequestration. In response to unidentified signals, NRF3 enters the nucleus and modulates gene expression. However, molecular mechanisms underlying the nuclear translocation of NRF3 and its target gene in cancer cells remain poorly understood. We herein report that multiple regulation of NRF3 activities controls cell proliferation. Our analyses reveal that under physiological conditions, NRF3 is rapidly degraded by the ER-associated degradation (ERAD) ubiquitin ligase HRD1 and valosin-containing protein (VCP) in the cytoplasm. Furthermore, NRF3 is also degraded by ß-TRCP, an adaptor for the Skp1-Cul1-F-box protein (SCF) ubiquitin ligase in the nucleus. The nuclear translocation of NRF3 from the ER requires the aspartic protease DNA-damage inducible 1 homolog 2 (DDI2) but does not require inhibition of its HRD1-VCP-mediated degradation. Finally, NRF3 mediates gene expression of the cell cycle regulator U2AF homology motif kinase 1 (UHMK1) for cell proliferation. Collectively, our study provides us many insights into the molecular regulation and biological function of NRF3 in cancer cells.


Asunto(s)
Factores de Transcripción con Cremalleras de Leucina de Carácter Básico/genética , Ciclo Celular/genética , Células Epiteliales/metabolismo , Regulación Neoplásica de la Expresión Génica , Péptidos y Proteínas de Señalización Intracelular/genética , Proteínas Serina-Treonina Quinasas/genética , Animales , Proteasas de Ácido Aspártico/genética , Proteasas de Ácido Aspártico/metabolismo , Factores de Transcripción con Cremalleras de Leucina de Carácter Básico/metabolismo , Células COS , Línea Celular Tumoral , Núcleo Celular/metabolismo , Proliferación Celular , Proteínas Cullin/genética , Proteínas Cullin/metabolismo , Citosol/metabolismo , Retículo Endoplásmico/metabolismo , Degradación Asociada con el Retículo Endoplásmico , Células Epiteliales/patología , Células HCT116 , Células HeLa , Humanos , Péptidos y Proteínas de Señalización Intracelular/metabolismo , Proteínas Serina-Treonina Quinasas/metabolismo , Proteínas Quinasas Asociadas a Fase-S/genética , Proteínas Quinasas Asociadas a Fase-S/metabolismo , Transducción de Señal , Factor de Células Madre/genética , Factor de Células Madre/metabolismo , Ubiquitina-Proteína Ligasas/genética , Ubiquitina-Proteína Ligasas/metabolismo , Proteína que Contiene Valosina/genética , Proteína que Contiene Valosina/metabolismo , Proteínas con Repetición de beta-Transducina/genética , Proteínas con Repetición de beta-Transducina/metabolismo
4.
Mymensingh Med J ; 26(3): 684-688, 2017 07.
Artículo en Inglés | MEDLINE | ID: mdl-28919629

RESUMEN

Acinar cell carcinoma (ACC) of the pancreas is a very rare neoplasm. We report a case of pancreatic acinar cell carcinoma involving the uncinate process of the pancreas. A 45 year old man presented with a painful upper abdominal mass without any jaundice or weight loss. Computed Tomography (CT) and Magnetic Resonance Cholangio-Pancreatography (MRCP) indicated a mass lesion in the uncinate process of the pancreas. He underwent Whipple's procedure (Pancreaticoduodenectomy). Histological slides revealed features of Acinar cell carcinoma (ACC) in the uncinate process of the pancreas and a lymph node.


Asunto(s)
Carcinoma de Células Acinares , Neoplasias Pancreáticas , Carcinoma de Células Acinares/cirugía , Humanos , Ganglios Linfáticos , Masculino , Persona de Mediana Edad , Neoplasias Pancreáticas/cirugía , Pancreaticoduodenectomía , Tomografía Computarizada por Rayos X
5.
Biochem Biophys Res Commun ; 484(1): 176-183, 2017 02 26.
Artículo en Inglés | MEDLINE | ID: mdl-28088524

RESUMEN

The transcription factor Nrf1 (NFE2L1) maintains protein homeostasis (proteostasis) by regulating the gene expression of proteasome subunits in response to proteasome inhibition. The deletion of the Nrf1 gene in neural stem/progenitor cells causes severe neurodegeneration due to the accumulation of ubiquitinated proteins in Purkinje cells and motor neurons (Nrf1 NKO mice). However, the molecular mechanisms governing this neurodegenerative process remain unclear. We demonstrate herein that the loss of Nrf1 leads to the reduced gene expression of the deubiquitinating enzymes (DUBs) but not proteasome subunits in Nrf1 NKO mice between P7 and P18. First, we show that K48-linked polyubiquitinated proteins accumulate in Nrf1-deficient Purkinje cells and cerebral cortex neurons. Nevertheless, loss of Nrf1 does not alter the expression and proteolytic activity of proteasome. A significantly reduced expression of deubiquitinating enzymes was also demonstrated in Nrf1-deficient cerebellar tissue using microarray analysis. The genome database further reveals species-conserved ARE, a Nrf1 recognition element, in the regulatory region of certain DUB genes. Furthermore, we show that Nrf1 can activate Usp9x gene expression related to neurodegeneration. Altogether these findings suggest that neurodegeneration in Nrf1 NKO mice may stem from the dysfunction of the ubiquitin-mediated regulation of neuronal proteins.


Asunto(s)
Cerebelo/enzimología , Enzimas Desubicuitinizantes/genética , Homeostasis/fisiología , Células-Madre Neurales/metabolismo , Factor Nuclear 1 de Respiración/fisiología , Animales , Cerebelo/patología , Enzimas Desubicuitinizantes/metabolismo , Regulación Enzimológica de la Expresión Génica , Ratones , Ratones Noqueados , Células-Madre Neurales/citología , Células-Madre Neurales/enzimología , Factor Nuclear 1 de Respiración/genética
6.
Mymensingh Med J ; 25(4): 635-640, 2016 10.
Artículo en Inglés | MEDLINE | ID: mdl-27941722

RESUMEN

Malnutrition is widely prevalent among hospitalized children in most developing countries including Bangladesh. Though malnutrition accounts for the high rate of under 5 mortality sometimes it is overlooked. Keeping in this in mind A comparative cross sectional study was done in Mymensingh Medical College Hospital from 1st October 2009 to 31st May 2011. Children aged 1-5 years with presence of one or more criteria WHM <70%, WHZ-score <-3SD, Bipedal edema & Mid upper arm circumference <110mm were taken as study group and children aged 1-5 years with normal growth allowable normal range of variation is between 3rd and 97th centile curve or median (50th centile) ±2SD of weight for age growth chart (CDC growth chart, USA, 2000) were taken as reference group. Persistent diarrhea, Patients taking medications containing zinc, copper, magnesium, phosphorus & calcium, PEM with shock were excluded from study group. Nutritional assessment was done according to WHO criteria of SAM. Serum Zinc, Copper Magnesium and Phosphorus level were determined by Atomic Absorption Spectrometry using UNICAM - AA Spectrometer, model no. 969, Spain. Total 120 study populations were taken. Ninety Out of 120 were taken as a study group (SAM) & 30 were reference group. In reference group serum Zn, Cu, Mg, P value was 103.80±8.86µg/dl, 135.92±13.57µg/dl, 2.31±0.18mg/dl, 3.96±0.22mg/dl respectively. In study group serum Zn, Cu, Mg, P value was 60.33±11.08µg/dl, 80.60±15.46µg/dl, 1.47±0.22mg/dl, 2.00±0.52mg/dl respectively. All these results show that there is significant difference between study group & reference group. Considering the decreased level of these parameters, close biochemical monitoring and follow up should be emphasized for the children with SAM.


Asunto(s)
Desnutrición Aguda Severa , Bangladesh , Preescolar , Cobre , Estudios Transversales , Humanos , Lactante , Magnesio , Fósforo , Zinc
7.
Biochem Biophys Res Commun ; 478(1): 363-370, 2016 09 09.
Artículo en Inglés | MEDLINE | ID: mdl-27416755

RESUMEN

The transcriptional factor Nrf1 (NF-E2-related factor 1) sustains protein homeostasis (proteostasis) by regulating the expression of proteasome genes. Under physiological conditions, the transcriptional activity of Nrf1 is repressed by its sequestration into the endoplasmic reticulum (ER) and furthermore by two independent ubiquitin-proteasome pathways, comprising Hrd1 and ß-TrCP in the cytoplasm and nucleus, respectively. However, the molecular mechanisms underlying Nrf1 activation remain unclear. Here, we report that USP15 (Ubiquitin-Specific Protease 15) activates Nrf1 in the nucleus by stabilizing it through deubiquitination. We first identified USP15 as an Nrf1-associated factor through proteome analysis. USP15 physically interacts with Nrf1, and it markedly stabilizes Nrf1 by removing its ubiquitin moieties. USP15 activates the Nrf1-mediated expression of a proteasome gene luciferase reporter and endogenous proteasome activity. The siRNA-mediated knockdown of USP15 diminishes the Nrf1-induced proteasome gene expression in response to proteasome inhibition. These results uncover a new regulatory mechanism that USP15 activates Nrf1 against the ß-TrCP inhibition to maintain proteostasis.


Asunto(s)
Núcleo Celular/metabolismo , Factor Nuclear 1 de Respiración/metabolismo , Complejo de la Endopetidasa Proteasomal/metabolismo , Factores de Transcripción/metabolismo , Proteasas Ubiquitina-Específicas/metabolismo , Ubiquitinación/fisiología , Células Cultivadas , Regulación de la Expresión Génica/fisiología , Células HEK293 , Células HeLa , Humanos
8.
Mymensingh Med J ; 21(1): 109-13, 2012 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-22314464

RESUMEN

This cross sectional study was conducted to assess seroprotection by completed 3 doses of hepatitis B vaccine in routine EPI schedule in preterm & LBW as well as term appropriate weight babies and to compare the immune response among them. The study was conducted in EPI centre of Dhaka Medical College Hospital where 50 preterm (<37 completed weeks of gestation) and low birth weight (<2500 gm) infants enrolled in group A and 50 term (37-42 completed weeks of gestation) appropriate weight (≥2500 gm) in group B. All infants were immunized with 3 doses of hepatitis B vaccine according to EPI schedule and first vaccine was given at 6 weeks after birth and subsequent doses are given at one month interval. Adverse events were monitored. Anti HBs titre was determined 1 month after 3rd dose of vaccine from serum by ELISA method (VITROS anti HBs reagent pack). Seroprotectivity (anti HBs titres >10 mIU/ml) of hepatitis B vaccine after 3 doses were 94% and 98% in group A and B respectively (p>0.05). However, the preterm infants had a lower geometric mean titre of antibodies after 3 doses of vaccine than did the term infants (92.75 mIU/ml vs. 310.59 mIU/ml respectively; p<0.001). After 3 doses of hepatitis B vaccine though the seroprotective anti HBs titre (i.e. >10 mIU/ml) was ~96% irrespective of gestational age and birth weight but good antibody titre (i.e. >100 mIU/ml) was found among preterm babies having gestational age >34 weeks (73.6%) and birth weight >2000 gm (64%).


Asunto(s)
Anticuerpos contra la Hepatitis B/sangre , Recien Nacido Prematuro/inmunología , Peso al Nacer , Estudios Transversales , Femenino , Edad Gestacional , Vacunas contra Hepatitis B , Humanos , Recién Nacido , Masculino
9.
J Perinatol ; 31(5): 361-7, 2011 May.
Artículo en Inglés | MEDLINE | ID: mdl-21311502

RESUMEN

OBJECTIVE: Immediate Kangaroo Mother Care (KMC), an intervention following childbirth whereby the newborn is placed skin-to-skin (STS) on mother's chest to promote thermal regulation, breastfeeding and maternal-newborn bonding, is being taught in very low-income countries to improve newborn health and survival. Existing data are reviewed to document the association between community-based KMC (CKMC) implementation and its potential benefits. STUDY DESIGN: New analyses of the sole randomized controlled study of CKMC in Bangladesh and others' experiences with immediate KMC are presented. RESULT: Newborns held STS less than 7 h per day in the first 2 days of life do not experience substantially better health or survival than babies without being held STS. CONCLUSION: Most women who were taught CKMC hold their newborns STS, but do so in a token manner unlikely to improve health or survival. Serious challenges exist to provide effective training and postpartum support to achieve adequate STS practices. These challenges must be overcome before scaling up.


Asunto(s)
Cuidado del Lactante , Enfermedades del Recién Nacido/epidemiología , Conducta Materna , Relaciones Madre-Hijo , Atención Posnatal/organización & administración , Tacto , Bangladesh , Regulación de la Temperatura Corporal , Lactancia Materna/psicología , Países en Desarrollo/estadística & datos numéricos , Femenino , Humanos , Cuidado del Lactante/organización & administración , Cuidado del Lactante/psicología , Mortalidad Infantil , Bienestar del Lactante/psicología , Bienestar del Lactante/estadística & datos numéricos , Recién Nacido , Apego a Objetos , Atención Posnatal/estadística & datos numéricos , Pobreza/psicología
10.
Nat Prod Commun ; 5(10): 1543-6, 2010 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-21121244

RESUMEN

The stem bark of Polyalthia simiarum has yielded a new bisnor-type clerodane diterpenoid, 2-oxo-14,15-bisnor-3,11E-kolavadien-13-one (1), and three previously known clerodane derivatives, kolavenic acid (2), 16beta-hydroxycleroda-3,13(14)Z-dien-15,16-olide (3), and 16-oxocleroda-3,13(14)E-dien-15-oic acid (4). The structures of these compounds were unambiguously determined by extensive NMR studies as well as by comparison with related compounds. Till now this is the second report of the occurrence of any unusual C-18 clerodane diterpenoid from nature. The crude light petroleum extract and the purified compound 3 demonstrated moderate free radical scavenging activity with IC50 values of 21.5 and 23.5 microg/mL, respectively.


Asunto(s)
Diterpenos de Tipo Clerodano/aislamiento & purificación , Polyalthia/química , Diterpenos/aislamiento & purificación , Diterpenos de Tipo Clerodano/química
11.
Health Policy Plan ; 22(5): 329-34, 2007 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-17698889

RESUMEN

OBJECTIVE: To assess the gender variations in delay from symptom onset to help seeking, diagnosis and treatment of tuberculosis (TB) using DOTS at community level, in 10 subdistricts of Bangladesh with 2.5 million people under a non-governmental organization's (Building Resources Across Communities, or BRAC) DOTS programme for TB control. DESIGN: A cross-sectional survey of 1000 newly diagnosed pulmonary TB patients (500 women and 500 men). FINDINGS: Women, in comparison with men, had significantly longer mean and median delays in total delay (63.2 and 61.0 days vs. 60.3 and 53 days, respectively), total diagnostic delay (61.2, 60.0 vs. 58.5, 52.0 days), patient's delay (51.9, 50.0 vs. 48.7, 42.0 days) and treatment delay (2.0, 1.0 vs. 1.9, 1.0 day). Patient's mean and median delays were longer than the health system delay. However, patient gender showed strong association with total delay, total diagnostic delay and patient's delay. Older age of women was significantly associated with longer patient and treatment delay categories, respectively. CONCLUSION: Compared with men, women experienced longer delays at various stages of the clinical process of help seeking for TB. This warrants appropriate measures to improve the situation.


Asunto(s)
Planificación en Salud Comunitaria/estadística & datos numéricos , Tuberculosis Pulmonar/diagnóstico , Tuberculosis Pulmonar/terapia , Adulto , Bangladesh , Estudios Transversales , Terapia por Observación Directa , Femenino , Humanos , Entrevistas como Asunto , Masculino , Factores Sexuales , Factores de Tiempo
12.
Anthropol Med ; 14(2): 139-51, 2007 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-27268389

RESUMEN

In addition to marginalization by poverty and ethnicity, gender is likely to contribute to vulnerability to TB-related stigma affecting women. Stigma often contributes to psychosocial problems and emotional suffering, and it may hinder help seeking and treatment adherence. TB-related stigma and its gender-specific features have not been carefully studied in Bangladesh, and such research is needed to reduce adverse effects of stigma. This study assessed and compared stigma in women and men, and identified crosscutting and gender-specific features of TB-related stigma. To assess stigma and the context of TB-related illness experience, meaning and help seeking behavior from patients' perspectives, a cultural epidemiological study administered a locally adapted semi-structured EMIC interview to 50 women and 52 men with pulmonary TB in rural Bangladesh. Indicators of TB-related stigma were assessed individually and collectively in a validated index. They were compared by sex, and illness narratives elaborated features of stigma with reference to features of TB. The study showed that six indicators of TB-related stigma were more prominent in accounts of women and two were more prominent in men's interviews. Gender differences appeared somewhat less after adjusting for other sociodemographic variables, and age was most significantly inversely related to stigma. Features of stigma more prominent in the accounts of women included feeling shamed or embarrassed, thinking less of themselves and feeling that others refused to visit or avoided them. Men were less likely to disclose their condition to a confidant, stay away from work or report that their spouse refused sex because of TB. Effective public health information and counselling sensitive to gender-specific features of stigma are needed to protect TB patients from the adverse impact of avoidable stigma. Further research is needed to clarify effects of gender-specific features of felt and enacted stigma on help seeking and treatment adherence.

13.
Int Braz J Urol ; 32(1): 31-4, 2006.
Artículo en Inglés | MEDLINE | ID: mdl-16519825

RESUMEN

INTRODUCTION: We aimed to investigate the rate of urinary retention after knee arthroplasty, the various factors involved in predicting those at risk for retention and to assess the impact of retention and catheterization on joint sepsis. MATERIALS AND METHODS: A retrospective review was conducted of all available case notes of patients undergoing total knee arthroplasty in a consecutive 2-year period (2000-2002). Adequate data was available for 142 patients. RESULTS: 142 patients underwent total knee arthroplasty. 19 patients were catheterized preoperatively for monitoring urine output. 123 patients were not catheterized. Urinary retention occurred in 19.7% (28/142). The mean day of catheterization for retention was 0.66. The mean duration of catheterization in patients developing retention was 3.58 days and was 3 days in the patients catheterized pre- or perioperatively. Deep joint sepsis occurred in 2.1% (3/142)--only one had been catheterized and that was preoperatively. No case of infection had urinary retention or had a symptomatic urinary tract infection. The only factors predicting those at significant risk of retention following knee arthroplasty was a past medical history of urinary retention (p = 0.049) and postoperative morphine requirement (p = 0.035). No patients required urological surgical intervention at mean follow up of 1.97 years. CONCLUSIONS: This study supports the use of indwelling urinary catheterization for patients developing urinary retention after total knee arthroplasty.


Asunto(s)
Artroplastia de Reemplazo de Rodilla/efectos adversos , Catéteres de Permanencia , Cateterismo Urinario , Retención Urinaria/etiología , Anciano , Femenino , Estudios de Seguimiento , Humanos , Masculino , Estudios Retrospectivos , Factores de Riesgo , Retención Urinaria/terapia
14.
Int. braz. j. urol ; 32(1): 31-34, Jan.-Feb. 2006.
Artículo en Inglés | LILACS | ID: lil-425494

RESUMEN

INTRODUCTION: We aimed to investigate the rate of urinary retention after knee arthroplasty, the various factors involved in predicting those at risk for retention and to assess the impact of retention and catheterization on joint sepsis. MATERIALS AND METHODS: A retrospective review was conducted of all available case notes of patients undergoing total knee arthroplasty in a consecutive 2-year period (2000-2002). Adequate data was available for 142 patients. RESULTS: 142 patients underwent total knee arthroplasty. 19 patients were catheterized preoperatively for monitoring urine output. 123 patients were not catheterized. Urinary retention occurred in 19.7 percent (28/142). The mean day of catheterization for retention was 0.66. The mean duration of catheterization in patients developing retention was 3.58 days and was 3 days in the patients catheterized pre - or perioperatively. Deep joint sepsis occurred in 2.1 percent (3/142) - only one had been catheterized and that was preoperatively. No case of infection had urinary retention or had a symptomatic urinary tract infection. The only factors predicting those at significant risk of retention following knee arthroplasty was a past medical history of urinary retention (p = 0.049) and postoperative morphine requirement (p = 0.035). No patients required urological surgical intervention at mean follow up of 1.97 years. CONCLUSIONS: This study supports the use of indwelling urinary catheterization for patients developing urinary retention after total knee arthroplasty.


Asunto(s)
Humanos , Masculino , Femenino , Anciano , Artroplastia de Reemplazo de Rodilla/efectos adversos , Catéteres de Permanencia , Retención Urinaria/etiología , Cateterismo Urinario , Estudios de Seguimiento , Estudios Retrospectivos , Factores de Riesgo , Retención Urinaria/terapia
15.
Public Health ; 120(3): 193-205, 2006 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-16438996

RESUMEN

Many studies have examined the health inequities between different social groups, often measured by individual independent variables, such as education, gender, ethnicity, geography, rich, poor, etc. Although inequities are increasingly widening, a few studies have looked at the health inequity between different poverty groups within the poor. The present study, using equity terms, examined the use of health services in two rural areas of Bangladesh. Using a multistage sampling method, a total of 80 villages were selected from the Bogra and Dinajpur sadar thanas (subdistricts) for the study. A total of 4003 households in these villages were visited for data collection on mortality and fertility, while data related to use of health services was collected from a subsample of 1032 households. A poverty index, constructed using three variables (household landholding, education level of head of household, and self-rated categorization of household's annual food security), categorized the households into three groups: extreme poor, moderate poor and non-poor. Overall, the data revealed considerable inequities in many study indicators between the poor and the non-poor. However, inequities of varying degrees were also found between the extreme poor and the moderate poor. Lower levels of inequities were found between the poor and the non-poor in the use of health services, which were easily accessible and free of charge (immunization, vitamin A capsule, etc.). On the whole, the extreme poor were less likely to use health services than the moderate poor and the non-poor, suggesting the need for a more appropriate programme to address their pressing health needs.


Asunto(s)
Accesibilidad a los Servicios de Salud/economía , Pobreza , Servicios de Salud Rural/estadística & datos numéricos , Factores Socioeconómicos , Bangladesh , Femenino , Encuestas de Atención de la Salud , Humanos , Masculino , Servicios de Salud Rural/provisión & distribución , Clase Social
16.
Mymensingh Med J ; 13(2): 181-4, 2004 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-15284698

RESUMEN

Patch Test was done in 340 suspected allergic contact dermatitis patients having different ages of both sexes during the period of January 2000 to December 2003 in the department of Dermatology and Venerology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka. Of these 340 cases 145 (42.65%) were male and 195 (57.35%) were female. Among these 340 cases, 250 (73.53%) cases were tested with international standard series allergen (ISS) and 90 (26.47%) cases with cosmetic series allergen (CSS), of which patch test was positive in 125 (50%) cases and 65 (72.22%) cases respectively. The 125 positive cases with ISS consisted of 56% male and 44% female. In 65 CSS positive cases 90.77% were female and 9.23% were male. Highest incidence of positive patch test was found in 61.54% cases in the age group of 30-39 years in ISS and 71.43% cases in the age group of 20-29 yrs in CSS. In ISS--Potassium Dichromate (19.2%), Fragrance mix (17.6%), Nickel Sulphate (15.2%) and PPD (11.2%) were found to be the common allergen and in CSS--Octyl Gallate (27.69%), Getrimide (18.92%), Balsum of Peru (15.38%), Thiomersal (12.31%) were found to be the common allergens.


Asunto(s)
Alérgenos/efectos adversos , Cosméticos/efectos adversos , Dermatitis Alérgica por Contacto/diagnóstico , Dermatitis Alérgica por Contacto/etiología , Pruebas del Parche , Adolescente , Adulto , Anciano , Bangladesh , Niño , Femenino , Humanos , Masculino , Persona de Mediana Edad
17.
J Perinatol ; 23(8): 646-51, 2003 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-14647161

RESUMEN

OBJECTIVE: Working with a multidisciplinary team of Ecuadorians, Bangladeshis and Americans, we developed a simple protocol for community-based implementation of kangaroo mother care (CKMC) that does not require birth weight or clinical judgment to identify which newborns should receive CKMC. CKMC could stabilize newborns and possibly reduce neonatal mortality where there is little medical care for newborns and low birth weight (LBW) is common. STUDY DESIGN: During their CKMC training, community-based workers identified 35 expectant or recently delivered women in the pilot study area and taught them about CKMC. Women were interviewed at 1 month postpartum to evaluate their experience with CKMC. RESULTS: In all, 77% of mothers initiated skin-to-skin care and 85% with LBW babies did so (37% were LBW). CKMC mothers delayed newborn bathing. Few slept upright with their newborns. CONCLUSIONS: CKMC was quickly and popularly adopted. A randomized controlled cluster trial is planned to determine whether CKMC reduces neonatal mortality.


Asunto(s)
Cuidado del Lactante/métodos , Relaciones Madre-Hijo , Adulto , Bangladesh , Ecuador , Femenino , Humanos , Recién Nacido , Proyectos Piloto , Postura , Sueño , Estados Unidos
19.
Arch Gerontol Geriatr ; 37(1): 77-91, 2003.
Artículo en Inglés | MEDLINE | ID: mdl-12849075

RESUMEN

The study aims to (i) describe regional variation and gender differences in health status of older people (60 years and older) in Bangladesh, indicated by self-reported health problems and functional ability; (ii) explore influence of socio-economic factors on health status of older people. In a cross-sectional study in rural and urban Bangladesh, 696 older persons were asked about their health problems and ability to manage activities of daily living (ADL). More than 95% of older people reported health problems. Approximately 80% of elderly women in both the regions reported having four or more health problems compared with 42% and 63% elderly men in the urban and rural regions, respectively. More women (urban: 55%; rural: 36%) than men (urban: 32%; rural: 22%) also reported difficulties with ADL. Irrespective of age, sex and area of residence, those reporting greater number of health problems were more likely to report difficulty with at least one ADL task. Reporting pattern of specific health problems varied between urban and rural regions. Socio-economic indicators were found to have little influence on reporting of health problems, particularly in the rural region. Observed regional difference may be related to the influence of social and environmental factors, and level of awareness concerning certain health conditions.


Asunto(s)
Actividades Cotidianas , Estado de Salud , Anciano , Bangladesh/epidemiología , Estudios Transversales , Femenino , Encuestas Epidemiológicas , Humanos , Modelos Logísticos , Masculino , Salud Rural , Factores Sexuales , Factores Socioeconómicos , Salud Urbana
20.
Public Health ; 117(2): 135-44, 2003 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-12802981

RESUMEN

This study attempted to measure the prevalence of lower limb clinical rickets using a rapid assessment methodology in Cox's Bazaar, a coastal district of Bangladesh. The study populations were drawn from 28 random villages representing all seven 'thanas' (subdistricts) of the district. Data were collected on 25,891 children and young people aged 1-20 years in two phases. In the first phase, 30 trained, local, non-medical people listed 490 children suffering from visible signs of any physical disability. To achieve this, they demonstrated a multicolored poster showing the features of lower limb clinical rickets to key informants in the villages. In the second phase, two teams of medically trained people (physicians), each with one male and one female, validated the above cases for rickets. They verified and validated 278 cases in five thanas. Due to inclement weather and floods, they could not visit the other two thanas. Based on these data, the adjusted prevalence rates for lower limb clinical rickets were calculated to be 931 per 100,000 population (95% confidence intervals 795-1067). The prevalence was highest (1215) in children aged 1-4 years and lowest (498) amongst 17-20 year olds. Females had lower prevalence than males. Based on the study experience, a quick investigation using a similar methodology was performed in five other districts (Sunamganj, Noakhali, Bhola, Jessore and Gaibandha), and clinical signs of lower limb rickets were found in Sunamganj and Jessore. It thus indicates that rickets may be endemic, not only in Cox's Bazaar but also in some other parts of Bangladesh. The methodology used for this study was found to be rapid, simple, replicable and inexpensive.


Asunto(s)
Pierna , Raquitismo/epidemiología , Adolescente , Adulto , Bangladesh/epidemiología , Niño , Preescolar , Femenino , Humanos , Lactante , Masculino , Prevalencia , Raquitismo/diagnóstico , Materiales de Enseñanza
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