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1.
BMJ ; 368: m517, 2020 Mar 23.
Artículo en Inglés | MEDLINE | ID: mdl-32205307

RESUMEN

The studyPowell J, Atherton H, Williams V, et al. Using online patient feedback to improve NHS services: the INQUIRE multimethod study. Health Serv Deliv Res 2019;7:38.This project was funded by the NIHR Health Services and Delivery Research programme (project number HS&DR 14/04/48).To read the full NIHR Signal, go to: https://discover.dc.nihr.ac.uk/content/signal-000861/online-patient-feedback-is-mostly-positive-but-is-not-being-used-effectively.


Asunto(s)
Retroalimentación , Satisfacción del Paciente , Medicina Estatal , Participación de la Comunidad , Humanos , Medicina Estatal/normas , Reino Unido
2.
BMJ ; 368: m520, 2020 Mar 25.
Artículo en Inglés | MEDLINE | ID: mdl-32213484

RESUMEN

The studyPalmer R, Dimairo M, Cooper C, et al. Self-managed, computerised speech and language therapy for patients with chronic aphasia post-stroke compared with usual care or attention control (Big CACTUS): a multicentre, single-blinded, randomised controlled trial. Lancet Neurol 2019;18:821-33.This project was funded by the NIHR Health Technology Assessment Programme (project number 12/21/01) and the Tavistock Trust for Aphasia.To read the full NIHR Signal, go to: https://discover.dc.nihr.ac.uk/content/signal-000864/after-a-stroke-computerised-speech-and-language-therapy-can-help-people-find-words.

3.
BMJ ; 368: m514, 2020 03 11.
Artículo en Inglés | MEDLINE | ID: mdl-32161036

RESUMEN

The studyThe CRASH-3 Trial Collaborators. Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial. Lancet 2019;394:1713-23.This trial was funded by NIHR Health Technology Assessment Programme (project number 14/190/01), JP Moulton Charitable Trust, Department of Health and Social Care, Department for International Development, Global Challenges Research Fund, Medical Research Council, and the Wellcome Trust (Joint Global Health Trials scheme).To read the full NIHR Signal, go to: https://discover.dc.nihr.ac.uk/content/signal-000870/tranexamic-acid-following-mild-to-moderate-traumatic-brain-injury-is-safe-and-reduces-deaths.

4.
BMJ ; 368: m512, 2020 Mar 06.
Artículo en Inglés | MEDLINE | ID: mdl-32144210

RESUMEN

The studyHewlett S, Almeida C, Ambler N, et al. Reducing arthritis fatigue impact: two-year randomised controlled trial of cognitive behavioural approaches by rheumatology teams (RAFT). Ann Rheum Dis 2019;78:465-72.Hewlett S, Almeida C, Ambler N, et al. Group cognitive behavioural programme to reduce the impact of rheumatoid arthritis fatigue: the RAFT RCT with economic and qualitative evaluations. Health Technol Assess 2019;23:57.This project was funded by the NIHR Health Technology Assessment Programme (project number 11/112/01).To read the full NIHR Signal, go to: https://discover.dc.nihr.ac.uk/content/signal-000860/group-cognitive-behavioural-courses-may-reduce-fatigue-from-rheumatoid-arthritis.


Asunto(s)
Artritis Reumatoide/complicaciones , Terapia Cognitivo-Conductual/métodos , Fatiga/prevención & control , Fatiga/terapia , Psicoterapia de Grupo/métodos , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad
5.
BMJ ; 368: m453, 2020 Feb 26.
Artículo en Inglés | MEDLINE | ID: mdl-32102784

RESUMEN

The studyCleland LC, McComb L, Kee F, et al. Effects of 20 mph interventions on a range of public health outcomes: a meta-narrative evidence synthesis. J Transp Health 2019. doi:10.1016/j.jth.2019.100633This project was funded by the NIHR Policy Research Programme (project number 17/149/19).To read the full NIHR Signal, go to: https://discover.dc.nihr.ac.uk/content/signal-000853/twenty-mph-speed-zones-reduce-the-danger-to-pedestrians-and-cyclists.


Asunto(s)
Accidentes de Tránsito/prevención & control , Conducción de Automóvil/legislación & jurisprudencia , Ciclismo/lesiones , Peatones , Heridas y Traumatismos/prevención & control , Ciclismo/legislación & jurisprudencia , Humanos , Reino Unido
6.
BMJ ; 368: l6775, 2020 01 31.
Artículo en Inglés | MEDLINE | ID: mdl-32005673

RESUMEN

The studyDambha-Miller H, Day AJ, Strelitz J, et al. Behaviour change, weight loss and remission of Type 2 diabetes: a community-based prospective cohort study. Diabet Med 2019. doi:10.1111/dme.14122This project was funded by the NIHR Health Technology Assessment Programme (project number 08/116/300) as well as the Wellcome Trust (grant number: G061895), the Epidemiology Unit programme (MC_UU_12015/4), and the National Health Service R&D support funding.To read the full NIHR Signal, go to: https://discover.dc.nihr.ac.uk/content/signal-000841/weight-loss-after-type-2-diabetes-diagnosis-boosts-chance-of-remission.


Asunto(s)
Diabetes Mellitus Tipo 2 , Pérdida de Peso , Peso Corporal , Humanos , Estudios Prospectivos , Medicina Estatal
7.
BMJ ; 368: l6768, 2020 01 10.
Artículo en Inglés | MEDLINE | ID: mdl-31924664

RESUMEN

The studyCabral C, Horwood J, Symonds J, et al. Understanding the influence of parent-clinician communication on antibiotic prescribing for children with respiratory tract infections in primary care: a qualitative observational study using a conversation analysis approach. BMC Fam Pract 2019;20:102.This project was funded by the NIHR School for Primary Care Research Programme (project number SPCR204).To read the full NIHR Signal, go to: https://discover.dc.nihr.ac.uk/content/signal-000829/gps-assessment-not-parental-expectation-drives-antibiotic-prescribing.


Asunto(s)
Antibacterianos , Infecciones del Sistema Respiratorio , Niño , Humanos , Motivación , Padres , Atención Primaria de Salud
8.
BMJ ; 368: l6779, 2020 01 15.
Artículo en Inglés | MEDLINE | ID: mdl-31941696

RESUMEN

The studyChappell LC, Brocklehurst P, Green ME, et al. Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial. Lancet 2019;394:1181-90.This project was funded by the NIHR Health Technology Assessment Programme (project number 12/25/03).To read the full NIHR Signal, go to: https://discover.dc.nihr.ac.uk/content/signal-000838/mothers-benefit-from-a-planned-earlier-delivery-for-late-pre-eclampsia.


Asunto(s)
Preeclampsia , Nacimiento Prematuro , Femenino , Humanos , Recién Nacido , Madres , Embarazo , Evaluación de la Tecnología Biomédica , Espera Vigilante
9.
BMJ ; 368: l6764, 2020 01 03.
Artículo en Inglés | MEDLINE | ID: mdl-31900245

RESUMEN

The studyCooper K, Breeman S, Scott NW, et al. Laparoscopic supracervical hysterectomy versus endometrial ablation for women with heavy menstrual bleeding (HEALTH): a parallel-group, open-label, randomised controlled trial. Lancet 2019;394:1425-36.The study was funded by the NIHR Health Technology Assessment Programme (project number 12/35/23).To read the full NIHR Signal, go to: https://discover.dc.nihr.ac.uk/content/signal-000837/keyhole-hysterectomy-is-effective-for-women-with-heavy-menstrual-bleeding.


Asunto(s)
Técnicas de Ablación Endometrial , Laparoscopía , Menorragia/cirugía , Femenino , Humanos , Histerectomía , Evaluación de la Tecnología Biomédica
10.
BMJ ; 367: l4962, 2019 11 04.
Artículo en Inglés | MEDLINE | ID: mdl-31685480

RESUMEN

The studyEveritt H, Landau G, Little P. Therapist telephone-delivered CBT and web-based CBT compared with treatment as usual in refractory irritable bowel syndrome: the ACTIB three-arm RCT. Health Technol Assess 2019;23:1-154.This project was funded by the NIHR Health Technology Assessment Programme (project number 11/69/02).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000784/irritable-bowel-syndrome-helped-by-telephone-or-internet-cbt.


Asunto(s)
Síndrome del Colon Irritable , Humanos , Internet , Logoterapia , Evaluación de la Tecnología Biomédica , Teléfono
11.
BMJ ; 367: l4993, 2019 11 04.
Artículo en Inglés | MEDLINE | ID: mdl-31685481

RESUMEN

The studyGilbert R, Brown M, Rainford N et al. Antimicrobial-impregnated central venous catheters for prevention of neonatal bloodstream infection (PREVAIL): an open-label, parallel-group, pragmatic, randomised controlled trial. Lancet Child Adolesc Health 2019;3:381-90.The study was funded by the NIHR Health Technology Assessment programme (project number 12/167/02).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000782/antimicrobial-central-venous-catheters-for-pre-term-babies-do-not-reduce-infections.


Asunto(s)
Antiinfecciosos , Bacteriemia , Catéteres Venosos Centrales , Antibacterianos , Niño , Humanos , Lactante , Recién Nacido , Evaluación de la Tecnología Biomédica
12.
BMJ ; 367: l5721, 2019 11 08.
Artículo en Inglés | MEDLINE | ID: mdl-31704711

RESUMEN

The studyCoomarasamy A, Devall AJ, Cheed V, et al. A randomised trial of progesterone in women with bleeding in early pregnancy N Engl J Med 2019;380:1815-24.This project was funded by the NIHR Health Technology Assessment Programme (project number 12/167/26).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000792/miscarriage-not-prevented-by-routine-use-of-progesterone.


Asunto(s)
Aborto Espontáneo , Femenino , Humanos , Embarazo , Progesterona , Evaluación de la Tecnología Biomédica
13.
BMJ ; 367: l5464, 2019 11 11.
Artículo en Inglés | MEDLINE | ID: mdl-31712247

RESUMEN

The studyLyttle MD, Rainford NEA, Gamble C, et al. Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial. Lancet 2019;393:2125-34.This trial was funded by the NIHR Health Technology Assessment Programme (project number 12/127/134).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000790/levetiracetam-vs-phenytoin-in-stopping-childrens-prolonged-epileptic-seizures.


Asunto(s)
Epilepsia , Estado Epiléptico , Niño , Humanos , Levetiracetam , Fenitoína , Convulsiones
14.
BMJ ; 367: l5456, 2019 10 01.
Artículo en Inglés | MEDLINE | ID: mdl-31575520

RESUMEN

The studyTaylor RS, Walker S, Ciani O, et al. Exercise-based cardiac rehabilitation for chronic heart failure: the EXTRAMATCH II individual participant data meta-analysis. Health Technol Assess 2019;23:1-98.This project was funded by the NIHR Health Technology Assessment Programme (project number 15/80/30).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000803/cardiac-rehabilitation-for-heart-failure-can-improve-quality-of-life-and-fitness.


Asunto(s)
Rehabilitación Cardiaca , Insuficiencia Cardíaca , Ejercicio , Terapia por Ejercicio , Humanos , Calidad de Vida
15.
BMJ ; 367: l5462, 2019 10 09.
Artículo en Inglés | MEDLINE | ID: mdl-31597637

RESUMEN

The studyPeden CJ, Stephens T, Martin G et al. Effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery (EPOCH): a stepped-wedge cluster-randomised trial. Lancet 2019;393:2213-21.This project was funded by the NIHR Health Services and Delivery Research Programme (project number 12/5005/10).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000789/national-quality-improvement-programmes-need-time-and-resources-to-have-impact.


Asunto(s)
Dolor Abdominal/cirugía , Procedimientos Quirúrgicos del Sistema Digestivo , Tratamiento de Urgencia , Mejoramiento de la Calidad/organización & administración , Enfermedad Aguda , Análisis por Conglomerados , Vías Clínicas , Procedimientos Quirúrgicos del Sistema Digestivo/normas , Tratamiento de Urgencia/normas , Humanos , Evaluación de Programas y Proyectos de Salud , Mejoramiento de la Calidad/normas
16.
BMJ ; 366: l5453, 2019 09 27.
Artículo en Inglés | MEDLINE | ID: mdl-31562125

RESUMEN

The studyTaylor S, Mallett S, Beare S et al. Diagnostic accuracy of whole-body MRI versus standard imaging pathways for metastatic disease in newly diagnosed colorectal cancer: the prospective Streamline C trial. Lancet Gastroenterol Hepatol 2019;4:529-37.This project was funded by the NIHR Health Technology Assessment Programme (project number 10/68/01).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000797/identifying-metastatic-disease-in-colorectal-cancer-with-whole-body-mri.


Asunto(s)
Neoplasias Colorrectales , Neoplasias Primarias Secundarias , Humanos , Imagen por Resonancia Magnética , Estudios Prospectivos , Evaluación de la Tecnología Biomédica
17.
BMJ ; 366: l4912, 2019 08 23.
Artículo en Inglés | MEDLINE | ID: mdl-31444168

RESUMEN

The studyFeatherstone K, Northcott A, Harden J, et al. Refusal and resistance to care by people living with dementia being cared for within acute hospital wards: an ethnographic study. Health Serv Deliv Res 2019;7.This study was funded by the National Institute for Health Research Health Services and Delivery Research Programme (project number 13/10/80).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000779/understanding-dementia-care-in-hospitals.


Asunto(s)
Demencia/enfermería , Demencia/psicología , Hospitalización , Cooperación del Paciente , Inglaterra , Humanos , Relaciones Profesional-Paciente , Medicina Estatal/normas , Gales
18.
BMJ ; 366: l4915, 2019 08 27.
Artículo en Inglés | MEDLINE | ID: mdl-31455630

RESUMEN

The studyA Rodger, V Cambiano, T Bruun, et al. Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study. Lancet 2019;393:2428-38.This project was funded by the NIHR Research for Patient Benefit Programme (project number PB-PG-1013-32069).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000785/antiretroviral-treatment-can-reduce-the-risk-of-hiv-transmission-between-male-partners-to-zero.


Asunto(s)
Infecciones por VIH , Minorías Sexuales y de Género , VIH , Humanos , Masculino , Estudios Prospectivos , Parejas Sexuales
19.
BMJ ; 366: l4920, 2019 08 29.
Artículo en Inglés | MEDLINE | ID: mdl-31466942

RESUMEN

The studyStory A, Aldridge R, Smith C, et al. Smartphone-enabled video-observed versus directly observed treatment for tuberculosis: a multicentre, analyst-blinded, randomised, controlled superiority trial. Lancet 2019;393:1216-24.The study was funded by the NIHR Programme Grants for Applied Research programme (project number RP-PG-0407-10340).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000777/smartphones-for-tb-treatment-observation.


Asunto(s)
Teléfono Inteligente , Tuberculosis , Humanos
20.
BMJ ; 366: l4230, 2019 07 02.
Artículo en Inglés | MEDLINE | ID: mdl-31266745

RESUMEN

The studyFawsitt C, Thom H, Hunt L. Choice of prosthetic implant combinations in total hip replacement: cost-effectiveness analysis using UK and Swedish hip joint registries data. Value Health 2019;22:303-12.This study was funded by the NIHR Research for Patient Benefit Programme (project number PB-PG-0613-31032).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000771/a-traditional-hip-implant-is-as-effective-as-more-expensive-newer-types-for-older-people.


Asunto(s)
Artroplastia de Reemplazo de Cadera , Diseño de Equipo , Prótesis de Cadera , Complicaciones Posoperatorias , Reoperación , Anciano , Artroplastia de Reemplazo de Cadera/efectos adversos , Artroplastia de Reemplazo de Cadera/instrumentación , Artroplastia de Reemplazo de Cadera/métodos , Cerámica/uso terapéutico , Análisis Costo-Beneficio , Diseño de Equipo/métodos , Diseño de Equipo/normas , Femenino , Prótesis de Cadera/clasificación , Prótesis de Cadera/normas , Humanos , Masculino , Prótesis Articulares de Metal sobre Metal , Osteoartritis de la Cadera/cirugía , Polietileno/uso terapéutico , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/cirugía , Falla de Prótesis/efectos adversos , Reoperación/métodos , Reoperación/estadística & datos numéricos , Reino Unido
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