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1.
Niger J Clin Pract ; 23(12): 1767-1771, 2020 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-33355833

RESUMEN

Alveolar bone loss subsequent to long-term edentulism and trauma may be severe and treatment plan is always an esthetic and functional challenge. Implant supported hybrid prosthesis is widely regarded as an effective treatment option for patients with excessive and irregular bone loss. However, implant placement is occasionally impossible without surgical procedures in such cases. This case report presents rehabilitation of 19-year-old maxillary anterior edentulous male patient with maxillary anterior bone defect and excessive cross-bite anterior closure with multidisciplinary approach. The patient was rehabilitated with implant supported hybrid prosthesis with Malo Bridge design following autogeneous iliac bone augmentation, teeth leveling with orthodontic treatment, and surgical placement of three implants. Esthetics, pleasing phonetics and function were achieved as desired with this treatment option and no complications were observed.


Asunto(s)
Pérdida de Hueso Alveolar , Aumento de la Cresta Alveolar , Implantes Dentales , Arcada Edéntula , Procedimientos Quirúrgicos Reconstructivos , Adulto , Pérdida de Hueso Alveolar/cirugía , Trasplante Óseo , Prótesis Dental de Soporte Implantado , Humanos , Arcada Edéntula/cirugía , Masculino , Maxilar/cirugía , Resultado del Tratamiento , Adulto Joven
2.
Niger J Clin Pract ; 23(9): 1328-1331, 2020 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-32913176

RESUMEN

It is possible to rehabilitate fully edentulous patients with implantsupported fixed or removable prostheses; however, implantsupported fixed prostheses are the gold standard for patients who not prefer to use removable dentures. This case report, prosthetic rehabilitation of a completely edentulous young patient with an implantsupported fixed hybrid prosthesis using the "Malo Bridge" technique is described. A 18 years old male patient was referred to the clinic with complaints of tooth loss, aesthetics, function, and phonetic. A total of 5 implants were placed in both the jaws. Considering that screw holes may cause aesthetic problems due to the Class III occlusion, these problems have been solved with the implant-supported hybrid prosthesis called Malo bridge. With the Malo Bridge design, the patient's aesthetic, functional and phonetic loss was eliminated, patient comfort and quality of life were improved, and patient expectations were met. It is a viable treatment option to rehabilitate completely edentulous jaws with a cross relationship and increase interarch distance using Malo Bridge to support a fixed prosthesis.


Asunto(s)
Implantes Dentales , Prótesis Dental de Soporte Implantado , Arcada Edéntula/rehabilitación , Maxilar/cirugía , Calidad de Vida , Pérdida de Diente/psicología , Adolescente , Diseño de Prótesis Dental , Retención de Dentadura/instrumentación , Humanos , Arcada Edéntula/cirugía , Masculino , Fonética , Radiografía Panorámica , Resultado del Tratamiento
3.
J. pediatr. (Rio J.) ; 83(4): 335-342, July-Aug. 2007. tab
Artículo en Portugués | LILACS | ID: lil-459889

RESUMEN

OBJETIVO: Investigar os fatores de risco associados à hipertensão arterial primária em adolescentes. MÉTODOS: Estudo caso-controle de base ambulatorial com adolescentes, de 12 a 20 anos incompletos, todos provenientes do Núcleo de Estudos da Saúde do Adolescente da Universidade Estadual do Rio de Janeiro. O estado nutricional foi avaliado através do índice de massa corporal. Obteve-se ainda a medida da circunferência abdominal, estatura, história familiar de hipertensão arterial, peso ao nascer e desenvolvimento puberal. A análise foi elaborada através de regressão logística não condicional. RESULTADOS: Participaram 91 casos e 182 controles. O índice de massa corporal mostrou-se associado à hipertensão. A estatura mostrou associação positiva com hipertensão apenas em meninas. Não se evidenciou associação entre desenvolvimento puberal e peso ao nascer com hipertensão arterial na adolescência. Por outro lado, a história familiar, principalmente quando ambos os pais são hipertensos, apresentou forte associação, tanto em meninos (OR = 13,32; IC95 por cento 2,25-78,94), como em meninas (OR = 11,35; IC95 por cento 1,42-90,21). CONCLUSÕES: Em nosso estudo, sobrepeso, obesidade e história familiar de hipertensão (pai e mãe hipertensos) foram os principais fatores de risco para o desenvolvimento de hipertensão arterial em adolescentes.


OBJECTIVE: To investigate the risk factors associated with essential arterial hypertension in adolescents. METHODS: A case-control, outpatients-based study of adolescents, aged 11 to 19 years, all treated at the Center for Studies into Adolescent Health (Núcleo de Estudos da Saúde do Adolescente) at Universidade Estadual do Rio de Janeiro. Nutritional status was assessed by means of body mass index. Data were also obtained on waist circumference, height, family history of arterial hypertension, birth weight and pubertal development. The analysis was performed using unconditional logistic regression. RESULTS: The study investigated 91 cases and 182 controls. Body mass index was associated with hypertension. Height had a positive association with hypertension only among the girls. There was no evidence of an association between pubertal development or birth weight with arterial hypertension in adolescence. In contrast, family history, particularly when both parents had hypertension, exhibited a robust association, both among the boys (OR = 13.32; 95 percentCI 2.25-78.94), and the girls (OR = 11.35; 95 percentCI 1.42-90.21). CONCLUSIONS: In our study, overweight, obesity and family history of hypertension (father and mother with hypertension) were the principal risk factors for arterial hypertension in adolescents.


Asunto(s)
Adolescente , Adulto , Niño , Femenino , Humanos , Masculino , Hipertensión/epidemiología , Obesidad/epidemiología , Índice de Masa Corporal , Brasil/epidemiología , Estudios de Casos y Controles , Estudios Transversales , Hipertensión/diagnóstico , Hipertensión/etiología , Obesidad/complicaciones , Obesidad/diagnóstico , Padres , Factores de Riesgo , Factores Socioeconómicos
4.
J Pediatr (Rio J) ; 83(4): 335-42, 2007.
Artículo en Inglés | MEDLINE | ID: mdl-17627321

RESUMEN

OBJECTIVE: To investigate the risk factors associated with essential arterial hypertension in adolescents. METHOD: A case-control, outpatient-based study of adolescents aged 11 to 19 years treated at the Center for Studies into Adolescent Health (Núcleo de Estudos da Saúde do Adolescente) at the Universidade Estadual do Rio de Janeiro. Nutritional status was assessed by means of body mass index. Data were also obtained on waist circumference, height, family history of arterial hypertension, birth weight and pubertal development. The analysis was performed using unconditional logistic regression. RESULTS: The study investigated 91 cases and 182 controls. Body mass index was associated with hypertension. Height had a positive association with hypertension only among the girls. There was no evidence of an association between pubertal development or birth weight with arterial hypertension in adolescence. In contrast, family history, particularly when both parents had hypertension, exhibited a robust association, both among the boys (OR = 13.32; 95%CI 2.25-78.94), and the girls (OR = 11.35; 95%CI 1.42-90.21). CONCLUSIONS: In our study, overweight, obesity and family history of hypertension (father and mother with hypertension) were the principal risk factors for arterial hypertension in adolescents.


Asunto(s)
Hipertensión/epidemiología , Obesidad/epidemiología , Adolescente , Adulto , Índice de Masa Corporal , Brasil/epidemiología , Estudios de Casos y Controles , Niño , Estudios Transversales , Femenino , Humanos , Hipertensión/diagnóstico , Hipertensión/etiología , Masculino , Obesidad/complicaciones , Obesidad/diagnóstico , Padres , Factores de Riesgo , Factores Socioeconómicos
5.
J Neurol Sci ; 214(1-2): 49-56, 2003 Oct 15.
Artículo en Inglés | MEDLINE | ID: mdl-12972388

RESUMEN

The human T-cell lymphotropic virus type 1 (HTLV-I) causes a neurological disease known as HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in a minority of infected individuals. Although other neurological outcomes have been described their prevalence is presently unknown. To evaluate the frequency and characteristics of neurological involvement in a population of HTLV-I-infected blood donors we investigated 196 HTLV-I positive and 196 negative blood donors from a blood center of Rio de Janeiro, Brazil. Individuals with abnormalities at the neurological examination were examined by three neurologists, and when pertinent, additional neurological investigations were performed. Descriptive analysis, Student's t-test and chi2 test were employed for statistical analysis. Neurological abnormalities were found in 71 (36.2%) of the HTLV-I positive blood donors and in only 29 (14.8%) of the HTLV-I negative donors (OR = 2.54, 95% CI = 1.67-3.59, p = 0.000002). Cases of myelopathy, motor neuron disease and myopathy were only found in the HTLV-I positive group. In addition, peripheral neuropathy (PN) was significantly more frequent in the positive group (p = 0.015). In summary, our data suggest that HTLV-I-infected individuals exhibit a wide variety of neurological manifestations apart from the classical picture of HAM/TSP.


Asunto(s)
Donantes de Sangre , Sistema Nervioso/fisiopatología , Paraparesia Espástica Tropical/fisiopatología , Adulto , Brasil , Femenino , Virus Linfotrópico T Tipo 1 Humano/aislamiento & purificación , Humanos , Masculino , Persona de Mediana Edad , Enfermedad de la Neurona Motora/epidemiología , Enfermedad de la Neurona Motora/fisiopatología , Enfermedades Musculares/epidemiología , Enfermedades Musculares/fisiopatología , Sistema Nervioso/patología , Sistema Nervioso/virología , Examen Neurológico , Paraparesia Espástica Tropical/sangre , Paraparesia Espástica Tropical/epidemiología , Nervios Periféricos/patología , Nervios Periféricos/fisiopatología , Enfermedades del Sistema Nervioso Periférico/epidemiología , Enfermedades del Sistema Nervioso Periférico/fisiopatología , Prevalencia
6.
Int J Cancer ; 101(1): 69-73, 2002 Sep 01.
Artículo en Inglés | MEDLINE | ID: mdl-12209590

RESUMEN

Somatic mutations in the TP53 gene are the most frequently observed genetic alterations in human malignancies, including breast cancer, which is one of the leading causes of death among women in Brazil. In our study, we determined the frequency and the pattern of TP53 mutations in malignant breast tumors from 120 patients living in Rio de Janeiro, Brazil. TP53 mutations were found in 20% of the tumors, which contained a diversity of mutation types: missense (62.5%), nonsense (8.3%), silent (4.2%), intronic (12.5%), insertion (4.2%) and deletion (8.3%). Of a total of 15 missense mutations, 4 were observed at Arg248 and 2 at Cys242, which are directly involved in DNA binding and in zinc binding, respectively. A subgroup of 51 patients was analyzed with respect to the relation between the presence of TP53 mutations and classical risk factors and with tumor and patient characteristics. For this analysis, we used logistic regression and, in order to obtain more precise confidence intervals, they were recalculated using a bootstrap resampling technique. Our results demonstrate that these mutations are not statistically associated with the risk factors or the patients' characteristics. However, the presence of TP53 mutations is strongly associated with the aggressiveness of the tumors, measured by Elston classification (OR = 11.97 and 95% CI of 2.24-307.05). This finding is in agreement with previous studies, which report the presence of TP53 mutations in tumors with poor prognosis. This correlation between tumor aggressiveness and TP53 mutations could be a crucial variable for the treatment and prognosis of breast cancer.


Asunto(s)
Neoplasias de la Mama/genética , Neoplasias de la Mama/patología , Predisposición Genética a la Enfermedad/genética , Mutación/genética , Proteína p53 Supresora de Tumor/genética , Adulto , Anciano , Consumo de Bebidas Alcohólicas , Brasil/epidemiología , Neoplasias de la Mama/epidemiología , ADN de Neoplasias/genética , Femenino , Humanos , Persona de Mediana Edad , Oportunidad Relativa , Reacción en Cadena de la Polimerasa , Polimorfismo Conformacional Retorcido-Simple , Fumar
7.
Artículo en Portugués | PAHO | ID: pah-22501

RESUMEN

Atualmente o perfil epidemiologico do Brasil acha-se representado pelo das doencas do subdesenvolvimento versus as da modernidade. Consequentemente, o pais enfrenta dificuldades no direcionamento simultaneo de acoes para a promocao da saude que contemplem controle, tanto das doencas transmissiveis quanto das doencas cronicas naotransmissiveis (DCNT). O presente trabalho objetivou descrever a situacao epidemiologica da saude do adulto brasileiro no que tange as DCNT e apresentar dados disponiveis sobre a qualidade assistencial e o impacto social destas doencas. Para isto realizou-se uma revisao da literatura desde que foi iniciada a producao e a divulgacao de dados sobre doencas cardiovasculares, cancer e diabetes (1964-1995). Foram leventadas 153 referencias bibliograficas e usadas 97. As autoras apontam as investigacoes basicas que poderiam ser realizadas em todas as regioes do pais para subsidiar o planejamento e a administracao de estrategias populacionais para fatores de risco e para tratamento e controle das doencas cronicas naotransmissiveis no Brasil (AU)


Asunto(s)
Enfermedad Crónica , Factores de Riesgo , Obesidad/epidemiología , Hipertensión , Escolaridad , Estudios Transversales , Diabetes Mellitus/mortalidad , Neoplasias/mortalidad , Brasil/epidemiología
8.
Cad. saúde pública ; 12(1): 53-9, jan.-mar. 1996. tab
Artículo en Inglés | LILACS | ID: lil-173602

RESUMEN

Realizou-se um estudo ecológico com base em dados de 10 capitais brasileiras e, através de análise de regressäo linear, examinou-se a associaçäo entre dieta e as taxas de mortalidade para as principais localizaçöes de câncer, entre adultos com 30 anos ou mais. As taxas de mortalidade ajustadas por idade variavam de 2,4 a 3,3 vezes entre as capitais. Consumo de energia associou-se positivamente com câncer de colon, pulmäo e esôfago (p menor ou igual 0,02 em cada associaçäo). Mortalidade por câncer de colon associou-se positivamente com o consumo de gordura, ovos, álcool, mate, cereais e vegetais (p menor ou igual 0,01); câncer de pulmäo associou-se ao consumo de mate e cereias (p menor ou igual 0,05); câncer de estômago associou-se positivamente com ovos (p=0,04) e, negativamente , com o consumo de fibras, frutas e vitaminas A e C (p menor ou igual 0,05). Câncer de esôfago foi positivamente associado com consumo de gordura e mate (p menor ou igual 0,05) e, negativamente, com vitamina A (p=0,02); câncer de próstata associou-se negativamente com vitamina C (p=0,007). Câncer de mama näo se associou a nenhum dos fatores estudados. A importante variaçäo nas taxas de mortalidade por câncer no Brasil podem ser parcialmente associadas as variaçöes em componentes da dietas ou a fatores a ale associados.


Asunto(s)
Encuestas sobre Dietas , Neoplasias/mortalidad , Ecología , Neoplasias/epidemiología
9.
Artículo | PAHO-IRIS | ID: phr-15472

RESUMEN

Atualmente o perfil epidemiologico do Brasil acha-se representado pelo das doencas do subdesenvolvimento versus as da modernidade. Consequentemente, o pais enfrenta dificuldades no direcionamento simultaneo de acoes para a promocao da saude que contemplem controle, tanto das doencas transmissiveis quanto das doencas cronicas naotransmissiveis (DCNT). O presente trabalho objetivou descrever a situacao epidemiologica da saude do adulto brasileiro no que tange as DCNT e apresentar dados disponiveis sobre a qualidade assistencial e o impacto social destas doencas. Para isto realizou-se uma revisao da literatura desde que foi iniciada a producao e a divulgacao de dados sobre doencas cardiovasculares, cancer e diabetes (1964-1995). Foram leventadas 153 referencias bibliograficas e usadas 97. As autoras apontam as investigacoes basicas que poderiam ser realizadas em todas as regioes do pais para subsidiar o planejamento e a administracao de estrategias populacionais para fatores de risco e para tratamento e controle das doencas cronicas naotransmissiveis no Brasil (AU)


Asunto(s)
Enfermedad Crónica , Factores de Riesgo , Obesidad , Hipertensión , Escolaridad , Estudios Transversales , Brasil , Diabetes Mellitus , Neoplasias
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