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1.
J Oral Sci ; 63(1): 92-97, 2020 Dec 23.
Artículo en Inglés | MEDLINE | ID: mdl-33311012

RESUMEN

PURPOSE: Implant component fractures are one of the most serious complications in implant treatment. With a better understanding of the risk factors for fracture in the preoperative, surgery, superstructure, and post-loading phases of implant treatment, low-risk treatment could reduce implant component fractures, leading to a better prognosis. The aim of this study was to clarify the risk factors for abutment and implant fractures that occur after loading, and to perform a retrospective, approximately 10-year follow-up study to explore the risk factors in each treatment phase. METHODS: Subjects were fitted with an implant prosthesis between January 2008 and December 2009. In total, 1,126 Ankylos implants in 430 patients were included for analysis. Binary logistic regression analysis was performed to extract factors related to non-fracture and fracture of the abutment or implant as a dependent variable. RESULTS: Gender (OR = 3.466, 95% CI 1.296-9.268, P = 0.013), gonial angle (OR = 3.420, 95% CI 1.308-8.945, P = 0.012), and splinting status of the superstructure (OR = 4.456, 95% CI 1.861-10.669, P = 0.001) were identified as significant risk factors. CONCLUSION: The risk of fracture is increased in males, especially those with a mandibular angle of less than 120° on panoramic radiographs, and those with a non-splinted superstructure.


Asunto(s)
Implantes Dentales , Implantes Dentales/efectos adversos , Prótesis Dental de Soporte Implantado , Fracaso de la Restauración Dental , Estudios de Seguimiento , Humanos , Masculino , Mandíbula , Estudios Retrospectivos , Factores de Riesgo
2.
J Prosthodont Res ; 2020 Oct 29.
Artículo en Inglés | MEDLINE | ID: mdl-33116029

RESUMEN

PURPOSE: To investigate the difference in improvement of oral health-related quality of life (OHR-QoL) depending on the oral and denture conditions of a complete denture wearer when using a cream or powder type denture adhesive in a 10-center parallel randomized clinical trial. METHODS: Two hundred edentulous subjects who wore complete dentures were allocated to each of the three groups according to denture adhesive type: cream, powder, and control (saline solution). The materials were applied to the mucosal surface of the dentures for 4 days, and baseline data and data after the intervention were collected. OHR-QoL was assessed using the Japanese version of the modified Oral Health Impact Profile for Edentulous Patients (OHIP-EDENT-J) scale for outcome. Multivariate analysis was used to investigate improvements in OHR-QoL according to participant characteristics among complete denture wearers using these materials. RESULTS: OHIP-EDENT-J scores were significantly decreased in all groups after the intervention (p < 0.05); however, there were no statistically significant differences among the groups. Multiple logistic regression analysis revealed a significant association between the vertical height of the maxillary and mandibular alveolar ridge and OHIP-EDENT-J scores in the cream-type denture adhesive group. In contrast, there were no significant association between participant characteristics and OHIP-EDENT-J scores in the powder-type adhesive and control groups. CONCLUSIONS: The use of denture adhesives could improve OHR-QoL for complete denture wearers. The cream-type denture adhesives may be expected to improve OHR-QoL in patients with poor residual ridge conditions compared with patients with good residual ridge conditions.

3.
Geriatr Gerontol Int ; 20(6): 607-614, 2020 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-32227400

RESUMEN

AIM: Previous studies on the association between intraoral conditions and mortality in community-dwelling older individuals reported that fewer present teeth (PT) are significant risk factors for mortality. However, how the number of PT relative to the number of functional teeth (FT), including both present and rehabilitated teeth, influences mortality has not been investigated fully. This study examined the impact of the number of FT on mortality among community-dwelling Japanese older adults. METHODS: This study was a retrospective, observational and population-based follow-up study, which examined 1188 older individuals who participated in an annual geriatric health examination from 2009 to 2015. The average follow-up period was 1697.0 ± 774.5 days. The primary outcome was all-cause mortality at follow-up. The numbers of PT and FT of each participant were counted during an oral examination. In addition, demographics, clinical variables, blood nutrient markers, physical functions and perceived masticatory function were measured. RESULTS: Kaplan-Meier analysis, followed by a log-rank test, revealed that fewer PT (P < 0.001) and FT (P = 0.002) were significantly associated with a reduced survival rate. Cox's proportional hazard analysis indicated that the number of FT, but not the number of PT, was a significant independent mortality risk factor after adjusting for demographics, clinical variables, nutrient markers and physical functioning (P = 0.036, hazard ratio: 2.089). CONCLUSIONS: Current results suggest that the number of FT more strongly predicts all-cause mortality than the number of PT among community-dwelling older adults. Further studies are necessary to consider the confounding of socioeconomic status and disability status. Geriatr Gerontol Int 2020; ••: ••-••.


Asunto(s)
Pérdida de Diente/mortalidad , Anciano , Anciano de 80 o más Años , Diagnóstico Bucal , Femenino , Estudios de Seguimiento , Evaluación Geriátrica , Humanos , Vida Independiente , Japón , Estimación de Kaplan-Meier , Masculino , Modelos de Riesgos Proporcionales , Estudios Retrospectivos , Factores de Riesgo
4.
J Prosthodont Res ; 64(4): 417-423, 2020 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-32061571

RESUMEN

PURPOSE: This randomized controlled trial aimed to study the effects of lining mandibular complete dentures with silicone-based resilient denture liners, especially with respect to sensation. METHODS: The trial included completely edentulous patients who were willing to fabricate new set of complete denture. A random permuted block method (block size: 4) was used to assign participants to one of the following groups: mandibular conventional denture (CD) group or mandibular denture with resilient denture liner (RD) group. The outcomes were evaluated using both, objective measures (current perception threshold (CPT) and pain threshold (PT)) for external stimuli measured using the Neurometer CPT® and subjective measures (physical pain and psychological discomfort measured using the Japanese version of Oral Health Impact Profile for Edentulous patients-OHIP-EDENT-J). The outcomes were measured twice, at immediately after completion of denture adjustments (first measurement), and 3 months after the completion of denture adjustments (second measurement). All outcomes were analyzed using the Student t-test. A p-value of <0.05 was considered statistically significant. RESULTS: CPT was significantly higher with RD than CD only at second measurement with frequency level of 2000 Hz and 5 Hz. The pain thresholds were significantly higher in the RD group than the CD group. The physical pain and psychological discomfort scores were significantly lower in the RD group than in the CD group. CONCLUSION: This study concludes that edentulous patients wearing mandibular complete dentures with silicone-based resilient denture liners dull perception mandibular ridge mucosa and felt less pain than those without the liners.


Asunto(s)
Alineadores Dentales , Resinas Acrílicas , Dentadura Completa , Dentadura Completa Inferior , Humanos , Dolor , Siliconas
5.
J Prosthodont Res ; 64(3): 281-288, 2020 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-31501069

RESUMEN

PURPOSE: The purpose of this study was to investigate the effect of denture adhesives on oral moisture in a 10-center parallel randomized clinical trial. METHODS: Two hundred edentulous subjects wearing complete dentures were allocated into three groups: cream-type adhesive, powder-type adhesive and control groups. The adhesives (and saline solution in the control group) were applied to the mucosal surface of the dentures for 4 days, and baseline data and data after the intervention for eight meals over 4 days were obtained. For the main outcome, oral moisture was measured with a moisture checking device. Secondary outcomes were denture satisfaction, masticatory performance, denture retention, and occlusal force. In addition to between-group and within-group comparisons of oral moisture, investigations for secondary outcomes were undertaken in subgroups classified according to the degree of oral moisture at baseline (normal subgroup and dry mouth subgroup). Intention-to-treat analysis was also performed. RESULTS: Between-group and within-group comparisons of oral moisture showed no significant differences. The cream-type and powder-type denture adhesives were significantly effective in the dry mouth group for denture satisfaction ratings of ability to masticate, stability, retention, and comfort of mandibular dentures (p<0.05). The masticatory performance and retentive force of the dry mouth denture adhesive using groups were significantly improved after intervention (p<0.05). CONCLUSIONS: The oral moisture of complete denture wearers was not influenced by the use of denture adhesives. Our findings showed that denture adhesives improved subjective denture satisfaction, masticatory performance, and retention for complete denture patients with oral dryness.


Asunto(s)
Cementos Dentales , Boca Edéntula , Retención de Dentadura , Dentadura Completa , Humanos , Masticación
7.
J Oral Sci ; 61(4): 508-511, 2019 Nov 27.
Artículo en Inglés | MEDLINE | ID: mdl-31631094

RESUMEN

The relation between occlusal force and general motor ability induced by lower-limb musculature is unclear. To identify indicators of oral and lower-limb muscle weakness, this study examined the relation between masticatory muscle strength and lower limb muscle force in 742 community-dwelling elderly adults (315 men and 427 women, mean age 73.3 ± 5.5 years) living in Itabashi ward, Tokyo. Multiple regression analysis of the relation between occlusal force and knee extension torque, in relation to age and sex, showed a significant correlation between the two variables (r = 0.348, P < 0.001), which indicates that occlusal force is a determinant of knee extension torque. Occlusal force remained significantly correlated with knee extension torque after adjustment for factors known to be related to the latter. In conclusion, chewing function and lower-limb motor function were significantly correlated and thus might be indicators of muscle weakness in elderly adults.


Asunto(s)
Fuerza de la Mordida , Vida Independiente , Adulto , Anciano , Femenino , Humanos , Rodilla , Masculino , Fuerza Muscular , Torque
8.
J Oral Rehabil ; 46(6): 556-562, 2019 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-30762250

RESUMEN

BACKGROUND: There is little evidence regarding the reliability of CPT and PT measurements to gauge mandibular perception. Thus, this study aimed to evaluate the test-retest reliability of CPT and PT values obtained from the mandibular oral mucosa and to test the bilateral differences in CPT and PT values obtained from the mental foramen region and buccal shelf region by a single operator. METHODS: CPT and PT values were obtained from the mental foramen and buccal shelf regions of 20 volunteers (10 males and 10 females; average age: 26.4 ± 2.6 years) by using the Neurometer CPT/C® device to deliver electrical stimulation. RESULTS: Relative and absolute reliabilities were confirmed over two measurements of CPT and PT over a 7- to 10-day measurement interval. Intra-class correlation coefficients (ICCs) for CPT and PT table obtained from the mental foramen region were >0.8, while most ICC for the buccal shelf region were <0.8. Standard error of measurement, minimal detectable change and Bland-Altman analyses showed that the CPT and PT measurements had no systematic error and could serve as useful methods. At all frequencies, the bilateral difference in CPT and PT values at the mental foramen and buccal shelf region was not significant. CONCLUSION: CPT and PT measurements using a custom-made device that applied an electrical current to the mental foramen region have appropriate reliability to assess intra-oral sensitivity to electrical stimulation in young adults.


Asunto(s)
Mucosa Bucal , Umbral del Dolor , Adulto , Mentón , Estimulación Eléctrica , Femenino , Humanos , Masculino , Reproducibilidad de los Resultados , Adulto Joven
9.
J Prosthodont Res ; 63(3): 299-302, 2019 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-30755360

RESUMEN

PURPOSE: This study aimed to investigate whether the mandible is more receptive to external stimuli than the maxilla in patients with complete dentures by comparing regional current perception thresholds (CPTs) and pain threshold (PTs). METHODS: A single operator obtained measurements from maxillae at the incisor foramen and the left side of the greater palatine foramen region and the mandible at the left side of the mental foramen region, using the Neurometer CPT/C device, CPT and PT values from the oral mucosa of 20 edentulous individuals wearing complete dentures were analyzed. Participant characteristics such as mucosal thickness, occlusal force, age, and sex. Mucosal thickness over target regions and occlusal force were measured by the same operator using Krupp SDM and Occlusal Force-Meter GM10s devices. Differences in CPT and PT among the three measurement regions were tested with an analysis of covariance, and post hoc t-tests with the Bonferroni correction. RESULTS: There were no significant differences between the mental foramen, incisor papilla, and greater palatine regions CPT values. PTs obtained at all current frequencies (2000Hz, 250Hz, and 5Hz) were lowest in the mental foramen region and highest in the greater palatine region. Covariates including sex, mucosal thickness, and occlusal force had no significant influence on CPT or PT values at all frequencies. CONCLUSIONS: The mandible exhibits higher receptivity to external pain stimuli than the maxilla.


Asunto(s)
Mandíbula , Maxilar , Dentadura Completa , Humanos , Umbral del Dolor , Paladar (Hueso)
10.
J Oral Rehabil ; 46(5): 409-416, 2019 May.
Artículo en Inglés | MEDLINE | ID: mdl-30588657

RESUMEN

BACKGROUND: Several methods exist for objectively evaluating chewing efficiency by using gummy jelly. However, the validity of the subjective visual evaluation of chewing efficiency has not been assessed. OBJECTIVE: To verify with an epidemiological study, the validity of a visual scoring method using gummy jelly by testing the relationship between masticatory performance (MP) using a fully automatic measuring system and visual score (VS) using a visual scoring method. METHODS: Community-dwelling elderly individuals (n = 1234) ≥70 years old participated. One evaluator measured VS consecutively after participants chewed the gummy jelly (ie, actual-VS). The chewed jelly was photographed. Two evaluators used the photograph to measure the gummy jelly (ie, photo-VS). To test the validity of both methods, the correlation between actual-VS and MP and between photo-VS and MP were analysed. Inter-rater reliability between the evaluators of photo-VS was analysed. RESULTS: Significant correlations existed between actual-VS and MP and between photo-VS and MP (r = 0.86-0.87; P < 0.001). The intra-class correlation coefficient of the inter-rater reliability for photo-VS was very high (0.93; P < 0.001; 95% confidence interval: 0.877-0.953); however, the distribution of photo-VS deviated slightly from the actual-VS. A large coefficient of variation in the MP for low VSs suggested the influence of incomplete comminution, which was not reflected by the VS, and the accidental swallowing of small pieces during chewing. CONCLUSION: The VS deviated slightly from the MP calculated using a fully automated method; however, the VS can be utilised for epidemiological surveys with numerous participants.


Asunto(s)
Geles/química , Masticación/fisiología , Percepción Visual/fisiología , Anciano , Fuerza de la Mordida , Femenino , Humanos , Japón/epidemiología , Estudios Longitudinales , Masculino , Tamaño de la Partícula , Fotograbar , Reproducibilidad de los Resultados , Propiedades de Superficie
11.
J Oral Sci ; 60(3): 399-404, 2018 Sep 23.
Artículo en Inglés | MEDLINE | ID: mdl-30146535

RESUMEN

Clear magnetic resonance imaging (MRI) is required to diagnose tongue cancer. However, the absence of occlusal support may cause tongue movements which are known to introduce artifacts on the MR image. This pilot study compared the manifest of artifacts from the tongue at rest and during motion using luminance standard deviation (LSD) to quantify the artifacts, in dentulous subjects. Participants were ten dentulous participants (5 males, 5 females; age 31.50 ± 8.38 years) with occlusal support. MRI was conducted with the tongue at rest and during lateral movement. The LSD was measured in the regions of interest (ROI) in the axial and sagittal planes. Tongue movement evoked unclear MR images, compared with the images taken at rest. Statistical analysis revealed that the LSD significantly differed between the tongue at rest and in motion in the axial (P = 0.004) and sagittal planes (ROI-A: P = 0.002, ROI-P: P = 0.006). These findings suggest that tongue movement introduces motion artifact and the LSD responds quantitatively to the magnitude of artifacts. Future studies will evaluate whether a prosthetic device used to provide occlusive support can decrease these artifacts when analyzed using LSD.


Asunto(s)
Artefactos , Imagen por Resonancia Magnética/métodos , Movimiento , Descanso , Lengua/fisiología , Adulto , Femenino , Humanos , Masculino , Proyectos Piloto , Neoplasias de la Lengua/diagnóstico por imagen
12.
Arch Gerontol Geriatr ; 78: 18-22, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-29883805

RESUMEN

PURPOSE OF THE STUDY: Sarcopenia has been identified as a health hazard in elderly people. Although the association between sarcopenia and a decrease in masticatory function has been reported, the mechanism underlying this association has not been widely reported. Therefore, in order to elucidate the relationship between sarcopenia and masticatory function, we examined whether the masseter muscle thickness (MMT), which is a factor influencing masticatory function, in community-dwelling elders is associated with the appendicular skeletal muscle index (SMI), a diagnostic criterion for sarcopenia. MATERIALS AND METHODS: MMT was measured in 774 community-dwelling elders aged 65 years or older at resting state via ultrasonography, and SMI was measured with the bioelectrical impedance method. The relationships were investigated by calculating Pearson's correlation coefficients. Multiple regression analyses adjusted for age and sex, SMI, and oral-related items were performed to determine the association between these factors. RESULTS: There was a significant correlation between the MMT and the SMI. The multiple regression analysis indicated that SMI was significantly associated with a decrease in MMT. CONCLUSIONS: The reduction in whole-body skeletal muscle mass in sarcopenia may be involved in the reduction in MMT. Prevention of sarcopenia may be an important factor for maintaining masticatory function in the elderly.


Asunto(s)
Músculo Masetero/anatomía & histología , Músculo Esquelético/anatomía & histología , Anciano , Anciano de 80 o más Años , Estudios Transversales , Femenino , Humanos , Vida Independiente , Masculino , Sarcopenia/diagnóstico
13.
J Dent ; 74: 30-36, 2018 07.
Artículo en Inglés | MEDLINE | ID: mdl-29758255

RESUMEN

OBJECTIVES: The use of a simplified method (S) of fabricating complete dentures has been shown to be more cost-efficient than the traditional method (T), and there are no negative consequences that detract from the cost savings in the short term. However, it is not clear whether this remains constant over a decade. The objective of this study was to clarify patients' perspectives and determine any differences between the dentures fabricated with these two different techniques after a decade of use. MATERIAL AND METHODS: Edentate individuals participated in a randomized controlled clinical trial and completed a 6-month follow-up from 2001 to 2003 (T group n = 50; S group n = 54). For this 10-year follow-up, they were interviewed by telephone. The assessment included whether the denture was still in use or replaced, the condition of the dentures, patient satisfaction and oral health-related quality of life (OHRQoL). Between and within-group differences and the factors that cause deterioration of oral health-related quality of life (OHRQoL) were determined. RESULTS: Among 54 responders (25 T and 29 S), 14T and 21S kept the original dentures. Both groups were similar in ratings of satisfaction and OHRQoL (maxilla T: 80.0 S: 86.0, p = 0.36; mandibular; T: 66.1 S: 72.3, p = 0.48; OHRQoL T: 111.1 S: 108.5, p = 0.46). Irrespective of fabrication method, discomfort, chewing difficulty and esthetics were the factors that deteriorate OHRQoL (adjusted r = 0.76, p < 0.001). CONCLUSION: The results indicate that the simplified method remains more cost-efficient than the traditional method over a 10-year period. (IRB approval: A09-E71-12 B McGill University, trial registry: ClinicalTrial.org; NCT02289443).


Asunto(s)
Diseño de Dentadura/métodos , Dentadura Completa/psicología , Satisfacción del Paciente , Calidad de Vida , Anciano , Diseño de Dentadura/economía , Retención de Dentadura , Dentadura Completa/efectos adversos , Estética Dental , Femenino , Estudios de Seguimiento , Humanos , Entrevistas como Asunto , Masculino , Masticación , Persona de Mediana Edad , Boca Edéntula , Encuestas y Cuestionarios , Resultado del Tratamiento
14.
J Prosthodont Res ; 62(3): 303-308, 2018 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-29361502

RESUMEN

PURPOSE: Tongue movement with unstable swallowing cause artifacts on magnetic resonance imaging (MRI). This may be associated with loss of occlusal support. This study aimed to clarify whether motion artifacts can be mitigated by denture wearing during MRI examination in patients without occlusal support, and whether denture wearing affect tongue stability, form, and position were also evaluated. METHODS: Ten subjects without occlusal support (6 male, 4 female; mean age 73.20±10.12 years) participated in the study. MRI was performed with dentures worn (DW), followed with removal of dentures (NDW). Luminance standard deviation (LSD) was measured in regions of interest in the axial and sagittal planes. The position of the base of the tongue (TB), tip of the tongue apex (TA), and tongue's long diameter (TLD) were compared between DW and NDW. RESULTS: NDW evoked ambiguous MR images in the axial and sagittal planes compared with DW. There were significant differences in LSD between DW and NDW in both the axial (p=0.047) and sagittal planes (p=0.02). No significant difference in the position of TB were observed (p=0.78). The position of TA was significantly more protruded with DW (p=0.007). Also, TLD was significantly longer with DW (p=0.001). CONCLUSIONS: Results of this study suggest that wearing the dentures during MRI examination reduces motion artifacts in edentulous patients without occlusal support, and maintained the normal form of the tongue during imaging.


Asunto(s)
Artefactos , Dentaduras , Imagen por Resonancia Magnética , Movimiento (Física) , Boca Edéntula/diagnóstico por imagen , Boca Edéntula/fisiopatología , Movimiento , Lengua/fisiología , Anciano , Anciano de 80 o más Años , Deglución/fisiología , Oclusión Dental , Femenino , Humanos , Masculino , Persona de Mediana Edad
15.
J Prosthodont Res ; 61(2): 113-122, 2017 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-27474364

RESUMEN

PURPOSE: A lingualized occlusion (LO) for complete dentures reduces lateral inferences and occlusal force contacts and direction; thus, LO is theorized to be more suitable for patients with compromised ridges than fully bilateral balanced articulation (FBBA). However, no studies have yet provided evidence to support LO in edentate patients with compromised alveolar ridges. The purpose of this study was to compare LO and FBBA in edentulous individuals with compromised ridges. METHODS: Sixty edentulous individuals were randomly allocated into groups and received dentures with either LO or FBBA. Following delivery, several denture-related satisfaction variables were measured using 100mm visual analogue scales; oral health-related quality of life (OHRQoL) was also assessed using the Oral Health Impact Profile (OHIP). Sub-group analyses of the effect of moderate and severe mandibular bone loss were also carried out. RESULTS: No significant differences were detected between LO and FBBA with the primary outcome. At 6 months, participants with severely atrophied mandibles and FBBA rated their satisfaction with retention of mandibular dentures significantly lower than those with LO (median LO: 86, FBBA: 58.5, p=0.03). They also had significantly lower OHRQoL for the domain of Pain (median LO: 4, FBBA: 5, p=0.02). General satisfaction and total OHIP scores significantly improved between baseline and 6 months only for the LO subjects with severely atrophied mandibles (satisfaction: p=0.003, OHIP total score: p=0.0007). CONCLUSIONS: The results indicate that the LO occlusal scheme with hard resin artificial teeth is more efficient for patients with severely resorbed mandibular ridges.


Asunto(s)
Oclusión Dental Balanceada , Oclusión Dental , Dentadura Completa/psicología , Boca Edéntula/psicología , Satisfacción del Paciente , Anciano , Anciano de 80 o más Años , Proceso Alveolar/patología , Fuerza de la Mordida , Método Doble Ciego , Femenino , Humanos , Masculino , Persona de Mediana Edad , Salud Bucal , Calidad de la Atención de Salud , Resinas Sintéticas , Diente Artificial
16.
Clin Exp Dent Res ; 3(4): 154-159, 2017 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-29744194

RESUMEN

The irritation and pain associated with oral blood sampling necessary to monitor glycemic control can alter oral sensation, but no studies have measured the reliability of oral sensation testing when performed concurrently with blood sampling. The primary and secondary aims of this study were to verify the measurement reliability of current perception threshold (CPT) and pain threshold (PT) tests performed before and after blood sampling and to investigate the differences in CPTs/PTs obtained from the oral cavity, hand, and foot, respectively. CPT/PT measurements were obtained from the oral mucosa and the tips of fingers and toes of 18 volunteers (10 males and 8 females, average age = 26.3 years) using electrical stimulation at frequencies of 5, 250, and 2,000 Hz. Participants also provided blood samples by pricking their own index fingers with a small needle. All subjects completed the following 3 conditions at once-weekly intervals as follows: (a) sensory measurements followed by blood sampling (SB block); (b) blood sampling followed by sensory measurements (BS block); (c) sensory measurements without blood sampling (CO control block). Cronbach's α coefficients were over 0.78 for the SB, BS, and CO blocks, and are considered to be acceptable for assuring measurement reliability. The oral cavity had significantly lower CPT/PTs than both hands and feet, such that the threshold increased in the order oral cavity < hand < foot. CPT and PT measurements performed concurrently with blood sampling are both reliable and region specific, and for which the oral cavity is the most sensitive testing region.

17.
Trials ; 17(1): 506, 2016 10 18.
Artículo en Inglés | MEDLINE | ID: mdl-27756441

RESUMEN

BACKGROUND: Denture adhesives, characterized as medical products in 1935 by the American Dental Association, have been considered useful adjuncts for improving denture retention and stability. However, many dentists in Japan are hesitant to acknowledge denture adhesives in daily practice because of the stereotype that dentures should be inherently stable, without the aid of adhesives. The aim of this study is to verify the efficacy of denture adhesives to establish guidelines for Japanese users. The null hypothesis is that the application of denture adhesives, including the cream and powder types, or a control (isotonic sodium chloride solution) would not produce different outcomes nor would they differentially improve the set outcomes between baseline and day 4 post-application. METHODS: This ten-center, randomized controlled trial with parallel groups is ongoing. Three hundred edentulous patients with complete dentures will be allocated to three groups (cream-type adhesive, powder-type adhesive, and control groups). The participants will wear their dentures with the denture adhesive for 4 days, including during eight meals (three breakfasts, two lunches, and three dinners). The baseline measurements and final measurements for the denture adhesives will be performed on the first day and after breakfast on the fourth day. The primary outcome is a general satisfaction rating for the denture. The secondary outcomes are denture satisfaction ratings for various denture functions, occlusal bite force, resistance to dislodgement, masticatory performance, perceived chewing ability, and oral health-related quality of life. Between-subjects comparisons among the three groups and within-subjects comparisons of the pre- and post-intervention measurements will be performed. Furthermore, a multiple regression analysis will be performed. The main analyses will be based on the intention-to-treat principle. A sample size of 100 subjects per group, including an assumed dropout rate of 10 %, will be required to achieve 80 % power with a 5 % alpha level. DISCUSSION: This randomized clinical trial will provide information about denture adhesives to complete denture wearers, prosthodontic educators, and dentists in Japan. We believe this new evidence on denture adhesive use from Japan will aid dentists in their daily practice even in other countries. TRIAL REGISTRATION: ClinicalTrials.gov NCT01712802 . Registered on 17 October 2012.


Asunto(s)
Adhesivos , Protocolos Clínicos , Dentadura Completa , Guías de Práctica Clínica como Asunto , Humanos
18.
J Prosthodont Res ; 60(2): 131-7, 2016 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-26787534

RESUMEN

PURPOSE: Osteoporosis contributes to impaired bone regeneration and remodeling through an imbalance of osteoblastic and osteoclastic activity, and can delay peri-implant bone formation after dental implant surgery, resulting in a prolonged treatment period. It poses several difficulties for individuals with large edentulous areas, and decreases their quality of life. Consequently, prompt postoperative placement of the final prosthesis is very important clinically. Peri-implant bone formation may be enhanced by systemic approaches, such as the use of osteoporosis supplements, to promote bone metabolism. We aimed to confirm whether intake of synthetic bone mineral (SBM), a supplement developed for osteoporosis, could effectively accelerate peri-implant bone formation in a rat model of osteoporosis. METHODS: Thirty-six 7-week-old ovariectomized female Wistar rats were randomly assigned to receive a standardized diet with or without SBM (Diet with SBM group and Diet without SBM group, respectively; n=18 for both). The rats underwent implant surgery at 9 weeks of age under general anesthesia. The main outcome measures, bone mineral density (BMD) and pull-out strength of the implant from the femur, were compared at 2 and 4 weeks after implantation using the Mann-Whitney U test. RESULTS: Pull-out strength and BMD in the Diet with SBM group were significantly greater than those in the Diet without SBM group at 2 and 4 weeks after implantation. CONCLUSIONS: This study demonstrated that SBM could be effective in accelerating peri-implant bone formation in osteoporosis.


Asunto(s)
Suplementos Dietéticos , Minerales/administración & dosificación , Osteogénesis , Osteoporosis/metabolismo , Animales , Densidad Ósea , Implantación Dental , Modelos Animales de Enfermedad , Femenino , Ratas , Ratas Wistar
19.
J Prosthodont Res ; 60(3): 199-205, 2016 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-26778580

RESUMEN

PURPOSE: A major complication associated with the use of resilient denture liners (RDLs) is a change in hardness over time. In vivo studies on the deterioration of RDLs over time are needed. We aimed to investigate the influence of patient characteristics on the hardness of acrylic-based RDLs (ARDLs) embedded in complete maxillary dentures. We hypothesized that 1 month after application of the ARDLs, the hardness would be influenced by age, saliva condition, occlusal force, smoking, drinking, denture wearing during sleeping, denture cleanser usage, and denture type. METHODS: Thirty complete maxillary denture wearers were recruited after obtaining informed consent. One investigator measured the Shore D hardness of the commercially available ARDLs, Soften (SFT), FD Soft (FDS), and Bio Liner (BIO) using a Vesmeter(®). The salivary flow rates and pH values and the occlusal force were measured for all patients before initiation of the study. T-tests and Pearson's correlation coefficients were used for the statistical analyses. A p-value of <0.05 was considered statistically significant. RESULTS: Smoking, wearing dentures while sleeping, use of denture cleansers, and denture type were associated with an increase in the hardness of the RDLs. The resting saliva pH only influenced the hardness of the SFT ARDLs. CONCLUSIONS: Smoking, denture wearing while sleeping, denture cleanser usage, denture type, and resting saliva pH are important predictors of the deterioration of ARDLs over time.


Asunto(s)
Resinas Acrílicas , Materiales Dentales , Alineadores Dentales , Dentadura Completa , Maxilar , Anciano , Anciano de 80 o más Años , Alisadura de la Restauración Dental , Limpiadores de Dentadura/efectos adversos , Femenino , Dureza , Humanos , Concentración de Iones de Hidrógeno , Masculino , Persona de Mediana Edad , Saliva/fisiología , Fumar/efectos adversos , Factores de Tiempo
20.
J Hard Tissue Biol ; 25(3): 257-262, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-28133434

RESUMEN

The present animal study investigated whether oral intake of synthetic bone mineral (SBM) improves peri-implant bone formation and bone micro architecture (BMA). SBM was used as an intervention experimental diet and AIN-93M was used as a control. The SBM was prepared by mixing dicalcium phosphate dihydrate (CaHPO4·2H2O) and magnesium and zinc chlorides (MgCl2 and ZnCl2, respectively), and hydrolyzed in double-distilled water containing dissolved potassium carbonate and sodium fluoride. All rats were randomly allocated into one of two groups: a control group was fed without SBM (n = 18) or an experimental group was fed with SBM (n = 18), at seven weeks old. At 9 weeks old, all rats underwent implant surgery on their femurs under general anesthesia. The implant was inserted into the insertion socket prepared at rats' femur to a depth of 2.5 mm by using a drill at 500 rpm. Nine rats in each group were randomly selected and euthanized at 2 weeks after implantation. The remaining nine rats in each group continued their diets, and were euthanized in the same manner at 4 weeks after implantation. The femur, including the implant, was removed from the body and implant was pulled out by an Instron universal testing machine. After the implant removal, BMA was evaluated by bone surface ratio (BS/BV), bone volume fraction (BV/TV), trabecular thickness (TbTh), trabecular number (TbN), trabecular star volume (Vtr), and micro-CT images. BS/BV, BV/TV, TbTh and Vtr were significantly greater in the rats were fed with SBM than those were fed without SBM at 2 and 4 weeks after implantation (P < 0.05). The present results revealed that SBM improves the peri-implant formation and BMA, prominent with trabecular bone structure. The effect of SBM to improve secondary stability of the implant, and shortening the treatment period should be investigated in the future study.

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