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1.
Int J Prosthodont ; 2021 Feb 12.
Artículo en Inglés | MEDLINE | ID: mdl-33616555

RESUMEN

PURPOSE: To evaluate the effects of 0.2% sodium hypochlorite, Efferdent (Prestige Consumer Healthcare), and 6.25% Ricinus communis on biofilm removal and antimicrobial action on dentures and brushes using nonimmersion or immersion protocols for the brushes. MATERIALS AND METHODS: A total of 45 denture wearers were randomly assigned to a denture immersion protocol for 7 days: 0.85% saline solution for 20 minutes (control); 0.2% sodium hypochlorite for 20 minutes (SH); Efferdent for 3 minutes; or 6.25% Ricinus communis for 20 minutes (RC). The participants were also randomized to immersion (n = 23) or no immersion (n = 22) of their brushes with their dentures in the same solutions. For biofilm evaluation, the dentures were stained and photographed, and the area of the biofilm was measured using Image Tool 3.0 (University of Texas Health Science Center). To evaluate microbial load on dentures and brushes, the biofilm was collected, and the Candida spp and Streptococcus mutans colonies were counted. RESULTS: The SH, Efferdent, and RC groups showed reduced biofilm and Candida spp on dentures regardless of the immersion protocol for the brushes. However, no difference was found in the Candida spp counts collected from the brushes immersed compared to the brushes not immersed in the solutions. The SH and Efferdent groups showed reduced S mutans on both dentures and brushes, except for in the nonimmersion subgroups. CONCLUSION: All solutions reduced denture biofilm and microbial load. However, immersion of brushes in the solutions did not contribute to reducing the microbial load.

2.
J Prosthodont ; 2021 Jan 19.
Artículo en Inglés | MEDLINE | ID: mdl-33464687

RESUMEN

PURPOSE: This prospective study evaluated and correlated the impact of ocular prostheses on quality of life and stress with socioeconomic level and clinical characteristics. The clinical difficulties and perceptions of patients after ocular rehabilitation were evaluated. METHODS: Anophthalmic patients (at least 18 years of age) who were not users of ocular prostheses were recruited. The Medical Outcomes Short-Form Health Survey (SF-36) and Perceived Stress Scale (PSS-10) questionnaires were administered before and after 3 and 6 months of prosthesis installation. Clinical characteristics, difficulties, and perceptions were evaluated by quantitative and descriptive analysis (7 days, 3 months, 6 months). Data were analyzed by the Friedman test and Pearson Correlation test (α = 0.05). RESULTS: The final sample consisted of 26 patients. Quality of life showed improvement in the "Bodily Pain" and "General Health" domains. Wearing the prosthesis did not influence perceived stress. The clinical evaluation showed clinical discharge over 6 months and presence of pain only at 7 days. A weak correlation occurred between sociodemographic characteristics and the categories "Role-Physical" (r = 0.423) and "General Health" (r = 0.494); cause of anophthalmia and "Role-Physical" (r = -0.471); and type of surgery and "General Health" (r = -0.432). CONCLUSIONS: According to the results of this study, the provision of ocular prostheses showed positive influence in 2 domains of quality of life and weak correlations with socioeconomic level, type of surgery, and cause of loss. Ocular rehabilitation did not influence stress. The use and care of the prostheses did not affect tissue inflammation, but the discharge was continuous. This article is protected by copyright. All rights reserved.

3.
Rev. SPAGESP ; 21(2): 97-110, jul.-dez. 2020. tab
Artículo en Portugués | LILACS, Index Psicología - Revistas técnico-científicas | ID: biblio-1125734

RESUMEN

A literatura menciona a importância do lazer na vida em família, ressaltando as interações significativas que promove e suas contribuições ao bem-estar da família. Buscou-se compreender a vivência do lazer a partir da perspectiva do grupo familiar, descrevendo as possíveis influências da experiência do lazer na dinâmica das mesmas. Participaram três famílias, que responderam a um questionário sociodemográfico e a uma entrevista do grupo familiar, além de terem produzido registros fotográficos de momentos de lazer. Para análise das entrevistas, incluindo os relatos acerca das fotografias, utilizou-se a Análise de Conteúdo. Verificou-se que as famílias descreveram atividades e concepções de lazer diversas e que todas mencionaram os efeitos positivos que a vivência coletiva do lazer gera às suas dinâmicas, favorecendo a convivência, o diálogo e a alegria. No entanto, as limitações de tempo, dinheiro, de acesso a opções de lazer e de conciliação das demandas de gerações diferentes foram descritos como empecilhos para a vivência familiar do lazer. Conclui-se refletindo acerca das implicações dos achados para políticas públicas de lazer e para uma educação para o lazer.


The literature mentions the importance of leisure in family life, highlighting the significant interactions it promotes and its contributions to family well-being. It sought to understand the experience of leisure from the perspective of the family group, describing the possible influences of the experience of leisure on their dynamics. Three families participated, who answered a sociodemographic questionnaire and an interview of the family group, besides having produced photographic records of leisure moments. For the analysis of the interviews, including the reports about the photographs, the Content Analysis was used. It was verified that the families described various leisure activities and conceptions and that all mentioned the positive effects that the collective experience of leisure generates to their dynamics, favoring the coexistence, the dialogue, and the joy. However, the limitations of time, money, access to leisure options, and the conciliation of the demands of different generations were described as impediments to the family experience of leisure. We conclude by reflecting on the implications of the findings for leisure public policies and leisure education.


En la literatura se menciona la importancia de la recreación en la vida familiar, destacando las importantes interacciones que promueve y sus contribuciones al bienestar de la familia. Trató de comprender la experiencia de recreación desde la perspectiva del grupo familiar, describiendo las posibles influencias de la experiencia de recreación en su dinámica. Participaron tres familias que respondieron a un cuestionario sociodemográfico y a una entrevista del grupo familiar, además de haber producido registros fotográficos de los momentos de recreación. Para el análisis de las entrevistas, incluyendo los informes sobre las fotografías, se utilizó el Análisis de Contenido. Se comprobó que las familias describían diversas actividades y concepciones de recreación y que todas mencionaban los efectos positivos que la experiencia colectiva de recreación genera a sus dinámicas, favoreciendo la convivencia, el diálogo y la alegría. Sin embargo, las limitaciones de tiempo, dinero, acceso a opciones de recreación y la conciliación de las demandas en las diferentes generaciones se describieron como impedimentos para la experiencia familiar de recreación. Concluimos reflexionando sobre las implicaciones de los hallazgos para las políticas públicas de recreación y para la educación del recreación.


Asunto(s)
Humanos , Masculino , Femenino , Calidad de Vida , Recreación , Familia , Composición Familiar , Relaciones Familiares , Fertilización , Actividades Recreativas
4.
Braz Dent J ; 31(6): 657-663, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-33237238

RESUMEN

The aim of this study was to evaluate the effect of cleaning solutions on the retention force of o-ring-type overdenture attachments. The effect of four solutions on nitrile rings were evaluated: Cepacol (C), Cepacol with fluoride (CF), Listerine (L) and 0.05% sodium hypochlorite (SH); deionized water (DW) was used as a control. Matrices containing two implants and abutments and acrylic specimens with the metal capsules were obtained and divided into the groups. A simulation of 90 overnight immersions (8 h) was performed, and the tensile strength value was obtained at the beginning (T0) and in every 30 days (T1, T2 and T3) (n=6). In order to analyze o-ring surface damage after the immersions, a scanning electron microscopy (SEM) was used (n=1). For statistical analysis of the results, analysis of variance (ANOVA) and multiple comparisons with Bonferroni adjustment (test power=1.000; a=0.05) were used. There was a significant difference for the factors time (p<0.001), solution (p<0.001) and for the interaction time × solution (p<0.001). Considering the times of each solution, only for DW there was no significant loss of retention over time. Comparing the solutions in each moment, there was no difference among the solutions in T0. From T1, CF and SH provided less retention than DW (p<0.005). Through SEM it was possible to observe changes in the surface of the CF and SH nitrile o-rings. CF and SH should be avoided due to deleterious action in o-rings.


Asunto(s)
Prótesis de Recubrimiento , Hipoclorito de Sodio , Prótesis Dental de Soporte Implantado , Análisis del Estrés Dental , Retención de Dentadura , Ensayo de Materiales , Resistencia a la Tracción
5.
Braz. dent. j ; 31(6): 657-663, Nov.-Dec. 2020. tab, graf
Artículo en Inglés | LILACS-Express | LILACS, BBO - Odontología | ID: biblio-1132344

RESUMEN

Abstract The aim of this study was to evaluate the effect of cleaning solutions on the retention force of o-ring-type overdenture attachments. The effect of four solutions on nitrile rings were evaluated: Cepacol (C), Cepacol with fluoride (CF), Listerine (L) and 0.05% sodium hypochlorite (SH); deionized water (DW) was used as a control. Matrices containing two implants and abutments and acrylic specimens with the metal capsules were obtained and divided into the groups. A simulation of 90 overnight immersions (8 h) was performed, and the tensile strength value was obtained at the beginning (T0) and in every 30 days (T1, T2 and T3) (n=6). In order to analyze o-ring surface damage after the immersions, a scanning electron microscopy (SEM) was used (n=1). For statistical analysis of the results, analysis of variance (ANOVA) and multiple comparisons with Bonferroni adjustment (test power=1.000; a=0.05) were used. There was a significant difference for the factors time (p<0.001), solution (p<0.001) and for the interaction time × solution (p<0.001). Considering the times of each solution, only for DW there was no significant loss of retention over time. Comparing the solutions in each moment, there was no difference among the solutions in T0. From T1, CF and SH provided less retention than DW (p<0.005). Through SEM it was possible to observe changes in the surface of the CF and SH nitrile o-rings. CF and SH should be avoided due to deleterious action in o-rings.


Resumo O objetivo do estudo foi avaliar o efeito de soluções higienizadoras sobre a força de retenção de encaixes do tipo o-ring. Foram avaliadas quatro soluções: Cepacol (C); Cepacol com flúor (CF), Listerine (L), hipoclorito de sódio 0,05% (HS) e água deionizada (controle/AD) em o-rings de nitrilo. Matrizes contendo dois implantes e pilares e espécimes em acrílico com as cápsulas metálicas foram obtidas e divididas entre os grupos. Foi realizada a simulação de 90 imersões noturnas (8 h), sendo obtido o valor da resistência à tração no início e a cada 30 dias (T0, T1, T2 e T3) por meio da máquina de ensaios mecânicos (n=6). Microscopia eletrônica de varredura (MEV) foi utilizada para análise de danos na superfície do o´ring após a imersão (n=1). Para análise estatística dos resultados foi utilizada análise de variância (ANOVA) e múltiplas comparações com ajuste de Bonferroni (poder do teste=1,000; a=0,05). Houve diferença significante para os fatores tempo (p<0,001), solução (p<0,001) e para interação de tempo × solução (p<0,001). Considerando-se os tempos de cada solução, apenas AD não apresentou perda significativa de retenção ao longo do tempo. Comparando as soluções em cada momento, não houve diferença entre as soluções em T0. A partir de T1, CF e HS propiciaram menor retenção quando comparados à AD (p <0,005). Através do MEV foi possível observar alterações nas superfícies dos o-rings de nitrilo imersos em CF e HS. O Cepacol com flúor e hipoclorito de sódio devem ser evitados devido à ação deletéria nos o-rings.

6.
Gerodontology ; 2020 Sep 30.
Artículo en Inglés | MEDLINE | ID: mdl-33000876

RESUMEN

PURPOSE: To investigate the impact of peroxide-based solutions in reducing viability and metabolic activity of multispecies biofilms on denture base acrylic resin surfaces and for removing them from these surfaces. BACKGROUND: Denture cleansers are effective in reducing monospecies biofilm; however, studies evaluating their action on multispecies biofilms are scarce. MATERIALS AND METHODS: Sixty-nine denture base acrylic resin specimens (Ø 15 × 3 mm) were sterilised then contaminated with Candida albicans, Staphylococcus aureus and Pseudomonas aeruginosa to form multispecies biofilms. Biofilms were grown for 24 hours; subsequently, specimens were immersed in three different cleansing solutions (n = 9): nitradine (NI), fixodent (FX) and phosphate-buffered saline (Control), according to the respective manufacturer's instructions. After applying the hygiene protocols, viability of microorganisms was evaluated by counting colony-forming units and assessing metabolic activity. Moreover, biofilm removal capacity was estimated based on extension of cell-covered areas visualised in fluorescent microscopy micrographics. RESULTS: Microbial counts were solution-dependent; NI was effective against all microorganisms (P < .05). FX exhibited moderate antimicrobial action, reducing P aeruginosa (P < .05) and S aureus (P < .05) viability by approximately 2 logs. Both peroxide-based solutions reduced metabolic activity (P < .001) and biofilm-covered areas on specimen surfaces (P < .001). CONCLUSION: Under the experimental conditions tested, these results demonstrated that peroxide-based solutions had favourable antimicrobial activity but promoted no broad elimination of aggregated multispecies biofilm. NI might be more suitable as complementary chemical agent for controlling multispecies denture biofilm.

7.
Front Microbiol ; 11: 580779, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-33123112

RESUMEN

Studies involving antimicrobial-coated endotracheal tubes are scarce, and new approaches to control multidrug-resistant Pseudomonas aeruginosa biofilm on these devices should be investigated. In this study, five new P. aeruginosa bacteriophages from domestic sewage were isolated. All of them belong to the order Caudovirales, Myoviridae family. They are pH and heat stable and produce 27 to 46 particles after a latent period of 30 min at 37°C. Their dsDNA genome (ranging from ∼62 to ∼65 kb) encodes 65 to 89 different putative proteins. They exhibit a broad lytic spectrum and infect 69.7% of the P. aeruginosa strains tested. All the bacteriophages were able to reduce the growth of P. aeruginosa strains in planktonic form. The bacteriophages were also able to reduce the biofilm viability rates and the metabolic activity of P. aeruginosa strains in a model of biofilms associated with endotracheal tubes. In addition, scanning electron microscopy micrographs showed disrupted biofilms and cell debris after treatment of bacteriophages, revealing remarkable biofilm reduction. The lytic activity on multidrug-resistant P. aeruginosa biofilm indicates that the isolated bacteriophages might be considered as good candidates for therapeutic studies and for the application of bacteriophage-encoded products.

8.
Arch Oral Biol ; 119: 104906, 2020 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-32947164

RESUMEN

OBJECTIVE: This study determined the prevalence of Candida spp. in the saliva of cancer patients. Furthermore, we assessed the antimicrobial activity of mouthwashes against the isolated strains and its susceptibility to amphotericin B and fluconazole. METHODS: Thirty-four cancer patients undergoing radiotherapy, chemotherapy alone or combined treatment were investigated for oral Candida spp. colonization and compared in regard to mucositis presence. The maximum inhibitory dilution was used to assess the antimicrobial activity of Periogard®, Cepacol® Cool Ice and 0.12 % Chlorhexidine Digluconate mouthwashes against the isolates. In parallel, susceptibility to amphotericin B and fluconazole was determined by agar-based E-test. Data did not adhere to normal distribution as inferred by the Shapiro-Wilk test and statistical analysis was conducted by non-parametric McNemar test (α0.05). RESULTS: Twenty-seven participants (79.4 %) were male, 19 (55.9 %) had mucositis and 9 (26.5 %) were colonized by Candida spp. 12 different strains of Candida spp. were isolated, being Candida albicans the most prevalent strain. Risk of Candida spp. colonization was increased by almost twofold among the participants with mucositis (odds ratio: 1.84; 95 % confidence interval: 0.37-9.07). Mouthwash Cepacol® Cool Ice presented better antimicrobial activity against Candida spp. while 0.12 % Chlorhexidine exhibited the worst activity. All strains were sensitive to amphotericin B, and 2 non-albicans strains were dose-dependent sensitive to fluconazole. CONCLUSION: Considering the increased risk of colonization byCandida spp. in patients with mucositis, and the emergence of antifungal drug resistance, the antiseptics use could benefit the maintenance of cancer patient's oral health.

9.
Int J Oral Maxillofac Implants ; 35(5): 888-899, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32991638

RESUMEN

PURPOSE: The aim of this study was to evaluate the formed biofilm on two types of implant surfaces (hydrophilic or hydrophobic) associated with titanium (Ti) or zirconia (Zn) abutments. MATERIALS AND METHODS: Samples were separated into four groups according to type of surface and abutment used (n = 10): (1) hydrophobic/Ti abutment, (2) hydrophilic/Ti abutment, (3) hydrophobic/Zn abutment, and (4) hydrophilic/Zn abutment. Implant-abutment assemblies were incubated with human saliva and supragingival biofilm. Samples of biofilm were evaluated by DNA Checkerboard hybridization, identifying up to 41 species. Scanning electron microscopy (SEM) images were obtained from the implants and abutments. RESULTS: The microbial count was higher for samples from groups with the hydrophilic/Ti abutment, followed by hydrophobic/Zn abutment, hydrophilic/Ti abutment, and hydrophobic/Zn abutment (P < .05). Hydrophilic surfaces and Zn abutments showed the highest counts of microorganisms. Individual bacterial counts were variable between groups; the hydrophilic/Zn abutment group had the highest microbial diversity, including T forsythia, P nigrescens, S oralis, S sanguinis, L casei, M orale, P aeruginosa, P endodontalis, S aureus, S gallolyticus, S mutans, S parasanguinis, S pneumoniae, and C albicans. The hydrophilic/Ti abutment group had the highest count of T forsythia and T denticola, microorganisms of Socransky red complex. The SEM images showed the bacterial colonization in both surfaces of the implant and abutment. CONCLUSION: Different surfaces of implants and abutments showed significant differences in the count and diversity of species. The hydrophilic/Zn abutment group presented the highest count and diversity of target species.


Asunto(s)
Implantes Dentales , Titanio , Biopelículas , Diseño de Implante Dental-Pilar , Genómica , Humanos , Ensayo de Materiales , Circonio
10.
Odontology ; 2020 Aug 04.
Artículo en Inglés | MEDLINE | ID: mdl-32749561

RESUMEN

Evaluate, through a randomized clinical trial, the efficacy of brushing associated with oral irrigation in maintaining implant and overdenture hygiene. Thirty-eight participants, who had a clinically acceptable conventional maxillary complete denture and mandibular overdenture retained by either implants or mini-implants using an O-ring-retained system, were enrolled to participate in the study. They were instructed to use two different hygiene methods, in a random sequence for a period of 14 days, with a 7-day wash-out interposed period: (I) mechanical brushing (MB); (II) association of mechanical brushing with oral irrigation (WP). Biofilms from both subgingival sulci and overdentures were collected and processed by Checkerboard DNA-DNA hybridization method at baseline and after using the proposed hygiene protocols. Comparisons were performed using Wilcoxon test and Friedman test with Benjamini-Hochberg false discovery rate, followed by Conover post-hoc test (α = 0.05). In the subgingival sulci-related biofilm, a lower number of microbial cells were detected, after WP compared to the MB method (P < 0.001). The findings of overdenture-related biofilm suggest that both methods were similar (P = 0.607) being the identified microbiota qualitatively coincident after each method. Despite the number of microbial counts, it was concluded that the association of mechanical brushing with oral irrigation was more effective in reducing microorganisms in the subgingival sulci biofilm; however, the same outcome was not observed in the overdentures.

11.
J Oral Implantol ; 2020 Jul 14.
Artículo en Inglés | MEDLINE | ID: mdl-32662827

RESUMEN

Implant-supported prostheses hygiene and peri-implant tissues health are considered to be predictive factors for successful prosthetic rehabilitation. Therefore, the purpose of this study was to evaluate the effectiveness of brushing associated with oral irrigation measured as biofilm-removing capacity, maintenance of healthy oral tissues, and patient satisfaction. A randomized, crossover clinical trial was conducted with 38 patients who wore conventional maxillary complete dentures and mandibular overdentures retained by the O-ring system. The patients were instructed to use the following hygiene methods for 14 days: mechanical brushing [MB (brush and dentifrice - Control)]; and MB with oral irrigation [WP (Waterpik - Experimental)]. Biofilm-removing capacity and maintenance of healthy oral tissues were evaluated by the Modified Plaque Index (PI), Gingival Index (GI), Probing Depth (PD), and Bleeding on Probing Index (BP) recorded at baseline and after each method. In parallel, patients answered a specific questionnaire using a Visual Analogue Scale after each hygiene method. Data were analyzed by Friedman and Wilcoxon tests (α=0.05). The results showed significantly lower PI, GI, PD, and BP indices after application of the hygiene methods (P<0.001) than those observed at baseline. However, no significant difference was found between MB and WP. The satisfaction questionnaire responses to both methods showed high mean values for all questions, with no statistically significant difference found between the answers given after the use of MB and WP (P>0.05). The findings suggest that WP was effective in reducing PI, GI, PD, and BP indices and provided a high level of patient satisfaction.

12.
Sci Rep ; 10(1): 9574, 2020 06 12.
Artículo en Inglés | MEDLINE | ID: mdl-32533091

RESUMEN

Cross-infection in contrast injectors is still a subject under discussion with little understanding. This study evaluated the biosafety of non-return valves (NRVs). Initially, the maximum pressure during backflow of intact and disrupted flexible diaphragms (FDs) from NRVs, as well as the functionality of connectors with NRVs were verified. The performance of air columns interposed by water in connectors with NRVs was analyzed, and the diffusion distance of crystal violet through connectors with NRVs was measured. The efficacy of NRVs as a barrier to bacterial contamination from backflow was evaluated. Finally, a clinical study of bacteriological contamination from syringes was conducted. There were differences among the maximum tolerated pressure by intact and disrupted FDs. Disrupted FDs showed no failures in the functionality of connectors with NRVs based on the lack of air bubbles released. Air columns could move through connectors with NRVs with intact and disrupted FDs. The longest diffusion distance of crystal violet was 6 cm of connector length, and NRVs showed efficacy as a barrier to bacterial contamination. In the clinical study, there was no bacterial growth in any of the evaluated samples. In conclusion, biosafety depends on the functionality of NRVs as well as proper practical clinical performance.

13.
J Med Virol ; 2020 May 06.
Artículo en Inglés | MEDLINE | ID: mdl-32374443

RESUMEN

Infections caused by the herpes simplex virus 1 (HSV-1), commonly called herpes simplex labialis (HSL), are a public health problem, reaching around 40% of the world's population. Thus, the search for effective therapeutic alternatives in the control of the limitations caused by this virus during the stages of evolution of the disease, is necessary, since they have a direct impact on the quality of life of the patients. The aim of the present study was to evaluate the efficacy of the in situ film precursor semisolid composition in the treatment of herpes simplex lesions in human HSV-1. Ninety-eight (n = 98) patients with HSV-1 were used for this study. The initial exclusion criteria left 81 patients to be considered in the present study. Three applications were performed, the first at time zero (T0) and the other two at 8 and 16 hours, after initial application (T8 and T16). Photographs were taken in the first appointment and 24 and 72 hours after the last application. After the three periods, each patient received a total amount of 90 mg of anesthetic and the prognosis of the patients was followed for 6 months and 1 year after the application. Frequency analysis showed that 40.3% of patients had remission of symptoms 24 hours after the last application. For the present study, the film presented a positive therapeutic potential and an esthetic benefit that is absent in the current products (ointments and gels). The invent presents dosage convenience (only three applications in a 24-hour period) and a low production cost, with a much shorter healing time than that reported using topical antiretrovirals.

14.
Int J Prosthodont ; 33(3): 315-320, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32320185

RESUMEN

PURPOSE: To evaluate the antimicrobial activity of effervescent tablets on the surfaces of cobalt-chromium (Co-Cr) and heat-polymerized resin. MATERIALS AND METHODS: From a metal matrix, 55 circular wax patterns (Ø 12 × 3 mm) were obtained and cast in Co-Cr alloy. Muffles for acrylic resin were prepared from circular wax patterns (Ø 20 × 5 mm). The metal specimens were positioned in the muffle, and the resin was pressed into its surroundings to simulate the composition of a removable partial denture (RPD). The mixed specimens were sterilized and contaminated with Streptococcus mutans, Staphylococcus aureus, Candida albicans, and Candida glabrata, composing a multispecies biofilm, and subsequently immersed according to the manufacturer's instructions in four cleansing solutions: Polident 3 Minute denture cleanser (P3M), Polident for Partials (PP), Corega Tabs (CT), and NitrAdine (Ni); as well as distilled water (positive control) and no contamination (negative control). After cleansing, viable microorganisms were quantified by counting the number of colony-forming units (CFU/mL). From the CFU values, log10(CFU + 1) values were calculated for statistical analysis. Kruskal-Wallis test with Dunn post hoc test were performed (α = .05). RESULTS: There was a significant reduction (P = .001) of S mutans after immersion in Ni (median [95% CI] 3.27 [2.92; 3.45]) compared to the CT (3.86 [3.75; 4.01]) and control (4.08 (3.73; 4.22]) groups, while the PP (3.63 [3.28; 4.11]) and P3M (3.83 [3.61; 4.04]) groups presented an intermediate action. The effervescent tablets did not present antimicrobial action against S aureus (P = .537), C albicans (P = .795), or C glabrata (P = .519). CONCLUSION: Ni exhibited moderate antimicrobial action. The effervescent tablets did not promote reduction of multispecies biofilm, and their daily use should be carefully considered.


Asunto(s)
Antiinfecciosos , Dentadura Parcial Removible , Biopelículas , Candida albicans , Limpiadores de Dentadura , Dentaduras , Streptococcus mutans , Propiedades de Superficie , Comprimidos
15.
Oral Dis ; 2020 Apr 05.
Artículo en Inglés | MEDLINE | ID: mdl-32248594

RESUMEN

OBJECTIVE: To evaluate a pilocarpine spray as a treatment for xerostomia in patients treated with radiotherapy (RT) for head and neck cancer (HNC). METHODS: This was a placebo-controlled, double-blind, crossover clinical trial of patients complaining of dry mouth after RT for HNC. Forty patients were randomly assigned to either placebo or pilocarpine (1.54%) spray and instructed to use three times a day for 3 months. After 1-month washout period, patients were crossed over to receive placebo or pilocarpine. The assessments were salivary flow (Stimulated Whole Saliva Flow - SWSF), xerostomia (Xerostomia Inventory - XI), and quality of life (QoL/Oral Health Impact Profile - OHIP-14), assessed at baseline, 1 hr (only SWSF), and at 1, 2, and 3 months of treatment. RESULTS: Posttreatment SWFS was not statistically different between pilocarpine and placebo regardless of the treatment sequence (paired T test; p > .05), except for the SWFS rates at 2 months after therapy. When comparing pilocarpine with placebo in the time points, there was no significant difference (p > .05) for QoL or XI. Significant differences in improvement in QoL and xerostomia experience appeared along time for pilocarpine group. CONCLUSION: The topical application of pilocarpine spray tested was similar to placebo on SWSF assessments in patients treated with RT for HNC.

16.
J Oral Implantol ; 46(3): 175-181, 2020 Jun 01.
Artículo en Inglés | MEDLINE | ID: mdl-32030425

RESUMEN

Rehabilitation with implant prostheses in posterior areas requires the maximum number of possible implants due to the greater masticatory load of the region. However, the necessary minimum requirements are not always present in full. This project analyzed the minimum principal stresses (TMiP, representative of the compressive stress) to the friable structures, specifically the vestibular face of the cortical bone and the vestibular and internal/lingual face of the medullary bone. The experimental groups were as follows: the regular splinted group (GR), with a conventional infrastructure on 3 regular-length Morse taper implants (4 × 11 mm); and the regular pontic group (GP), with a pontic infrastructure on 2 regular-length Morse taper implants (4 × 11 mm). The results showed that the TMiP of the cortical and medullary bones were greater for the GP in regions surrounding the implants (especially in the cervical and apical areas of the same region) but they did not reach bone damage levels, at least under the loads applied in this study. It was concluded that greater stress observed in the GP demonstrates greater fragility with this modality of rehabilitation; this should draw the professional's attention to possible biomechanical implications. Whenever possible, professionals should give preference to use of a greater number of implants in the rehabilitation system, with a focus on preserving the supporting tissue with the generation of less intense stresses.


Asunto(s)
Implantes Dentales , Prótesis Dental de Soporte Implantado , Análisis del Estrés Dental , Dentadura Parcial Fija , Análisis de Elementos Finitos , Estrés Mecánico
17.
J Prosthet Dent ; 124(6): 690-698, 2020 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-31955835

RESUMEN

STATEMENT OF PROBLEM: Antifungals are used to treat Candida infections. However, because of increased antifungal resistance and the length of antifungal therapy, Candida spp. infections can be prevented using the prosthesis hygiene method. Therefore, establishing efficient, safe, and low-cost hygiene protocols for complete denture wearers is necessary. PURPOSE: The purpose of this clinical trial was to compare 10% Ricinus communis (RC10%) and 0.5% chloramine-T (CT0.5%) with negative (water) and positive (0.25% sodium hypochlorite [SH0.25%]) controls to establish a protocol to treat denture stomatitis (DS), remove denture biofilm, reduce overall microbiota, and decrease Candida spp. on the palate and denture bases. MATERIAL AND METHODS: This randomized, double blind, controlled clinical trial allocated 60 DS-positive participants in parallel groups: RC10%, CT0.5%, negative control, and SH0.25%. All participants brushed their palate and dentures and applied 1 of the solutions only to the denture. The following outcomes were assessed at baseline and after 7 and 37 days: Candida spp. counts, frequency of species by presumptive identification, DS severity, and photographic quantification of biofilm. The Kruskal-Wallis and Friedman tests with stepwise step-down post hoc test compared the anticandidal effect and the DS score (between groups and time). ANOVA and the Tukey post hoc test were used for biofilm removal comparison (α=.05). RESULTS: Microbial counts were solution- and time-dependent for dentures, with C. albicans, C. tropicalis, and C. glabrata being the most prevalent species. RC10% presented similar results to baseline and control after 7 and 37 days. CT0.5% reduced the CFU/mL compared with the baseline. SH0.25% was the most effective. DS reduced in all groups, independent of the solution. SH0.25% reduced biofilm the most, followed by RC10%. CT0.5% was similar to the control. CONCLUSIONS: SH0.25% demonstrated potential for Candida spp. control in denture wearers with DS. The other protocols showed intermediate activity and might be more suitable for longer immersion periods.

18.
J Prosthodont ; 29(2): 142-150, 2020 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-30381847

RESUMEN

PURPOSE: To compare the effect of solutions of effervescent tablets (ET), cetylpyridinium chloride (CPC), and experimental solutions of Ricinus communis on the surface of cobalt-chromium (Co-Cr) alloys. MATERIALS AND METHODS: Fifty-five specimens of Co-Cr were prepared by the lost-wax casting method using circular patterns (∅12 × 3 mm). The specimens were randomly divided into 5 groups: deionized water (control); 2% R. communis; 10% R. communis; ET, and CPC. The surface roughness of specimens (n = 10) was evaluated before immersion (baseline), and at simulated times of ½, 1, 2, 3, 4, and 5 years, by laser confocal microscope (Sa, µm) and profilometer (Ra, µm). The surface topography and chemical composition (n = 1) was qualitatively analyzed with scanning electron microscopy (SEM), and energy dispersive X-ray spectrometry (EDS). Data were subjected to Kruskal-Wallis followed by Dunn tests, and Friedman followed by Wilcoxon tests (α = 0.05). RESULTS: For Sa, there was no difference for the solution factor. For the time factor a significant difference was found with 2% R. communis solution among baseline and ½, 2, 3, and 5 years (p < 0.001) and with 10% R. communis solution between 1 and 2 years (p = 0.007), with decreasing roughness over time. For Ra, cetylpyridinium chloride exhibited less roughness than 10% R. communis solution in ½ (p = 0.048) and 5 years (p = 0.013). In the SEM and EDS analysis the solutions did not present deleterious effects or changes in the chemical composition on the surfaces. CONCLUSIONS: Although a significant difference was found for the roughness, the results, below 0.2 µm, are clinically acceptable. Thus, all solutions can be used safely in removable partial denture cleaning for a period of 5 years.


Asunto(s)
Limpiadores de Dentadura , Dentadura Parcial Removible , Aleaciones de Cromo , Ensayo de Materiales , Propiedades de Superficie
19.
Microsc Res Tech ; 83(2): 133-139, 2020 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-31663194

RESUMEN

This study aimed to investigate dentin wettability and surface morphology after selective removal of carious lesion by erbium-doped yttrium aluminum garnet (Er:YAG) laser, followed by dentin biomodification with carbodiimide (EDC) and chitosan (CHI). Seventy-eight bovine dentin specimens were submitted to caries induction. Specimens were distributed according to methods of carious removal (n = 39): bur at low-speed (40,000 rpm) or Er:YAG laser (noncontact mode, 250 mJ/pulse and 4Hz). All specimens were etched with 35% phosphoric acid, and subdivided according to dentin biomodification (n = 13): Control (no biomodification), EDC or CHI. The contact angle (n = 10) between adhesive system (3M ESPE) and dentin surface was measured by a goniometer. Eighteen specimens (n = 3) were analyzed by scanning electron microscopy. Data were analyzed by two-way ANOVA and Tukey's test (α = .05). The method used to remove carious lesion did not influence the wettability of dentinal surface (p = .748). The angles produced on the remaining dentin after biomodification were influenced (p = .007). CHI promoted higher contact angles (p = .007) and EDC did not differ from the control group (p = .586). In the bur-treated group, most tubules were open, regardless of which biomodifier was used. Laser modified the organic matrix layer. CHI promoted partially closed tubules in some areas while EDC exposed dentinal tubules. Regardless of which method was used for selective removal of carious lesion, biomodification with EDC did not affect the dentin wettability, whereas CHI changed the wettability of remaining dentin. Both biomodifiers promoted a slight change on dentin morphology.


Asunto(s)
Carbodiimidas/farmacología , Quitosano/farmacología , Caries Dental/radioterapia , Dentina/efectos de los fármacos , Láseres de Estado Sólido/uso terapéutico , Adhesivos , Animales , Bovinos , Erbio/farmacología , Incisivo/efectos de los fármacos , Microscopía Electrónica de Rastreo , Ácidos Fosfóricos/farmacología , Propiedades de Superficie , Humectabilidad
20.
J Mech Behav Biomed Mater ; 103: 103556, 2020 03.
Artículo en Inglés | MEDLINE | ID: mdl-31785542

RESUMEN

PURPOSE: This study used digital image correlation (DIC) to evaluate the strain transferred by splinted and non-splinted screw-retained fixed partial dentures (FPDs) supported by short and conventional implants. MATERIAL AND METHODS: Four polyurethane models were fabricated to simulate half of the mandibular arch with acrylic resin replicas of the first premolar. Short (5 mm) and/or conventional (11 mm) implants replaced the second premolar and the first and second molars. Groups were: G1, two conventional (second premolar and first molar) and one short (second molar) implant; G2, one conventional (second premolar) and two short (first and second molar) implants; G3, three short implants; and G4, three conventional implants. Splinted (S) and non-splinted (NS) FPDs were screwed to the implant abutments. Occlusal load and a single point load on the second premolar, both of 250 N, were applied. Strain in the horizontal direction (Ɛxx) was calculated and compared using the DIC software. RESULTS: Splinted crowns presented the highest strain magnitudes of all tested groups (p < 0.05). The strain was concentrated near the short implants and presented a higher magnitude compared to conventional implants, especially in G2S (-560.13 µS), G3S (-372.97 µS), and G4S (-356.67 µS). CONCLUSIONS: Splinted crowns presented a higher strain concentration around the implants, particularly near the implant replacing the first molar. A combination of short and conventional implants seems to be a viable alternative for the rehabilitation of the posterior edentulous mandible with reduced bone height.

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