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J Craniofac Surg ; 2020 Jul 14.
Artículo en Inglés | MEDLINE | ID: mdl-32675770


BACKGROUND: Surgical resection of maxillary tumors can result in defects that can be difficult to reconstruct by conventional means due to the complex functional and anatomic nature of the midface and lack of regional bone flap options in the head and neck. Many reconstructive methods have been used to repair maxillary defects, but the ideal technique for the reconstruction of hemi-maxillectomy defects in growing pediatric patients has yet to be determined. METHODS: The authors present a rare pediatric patient with melanotic neuroectodermal tumor of infancy resulting in a hemi-maxillectomy defect after resection that was reconstructed using a pedicled vascularized composite flap consisting of temporalis muscle, pericranium, and parietal bone. RESULTS: The patient achieved successful long-term bony reconstruction of his right maxilla with this flap. Stable skeletal fixation with adequate orbital support was maintained over a >3-year follow-up period. CONCLUSION: A vascularized composite parietal bone flap is a reliable reconstructive option for reconstruction of large maxillectomy defects providing low donor-site morbidity, adequate globe support, excellent long-term skeletal stability, and malar symmetry in rapidly growing pediatric patients. Successful reconstruction for a rare patient with maxillary melanotic neuroectodermal tumor of infancy requiring hemi-maxillectomy was demonstrated with >3-year follow-up.

Plast Reconstr Surg ; 2020 Jun 23.
Artículo en Inglés | MEDLINE | ID: mdl-32590515


BACKGROUND: Facial asymmetry due to unilateral condylar hyperplasia (UCH) requires treatment to address facial and occlusal imbalances. There is no definitive evidence to suggest that a single intervention strategy (during either active condylar overgrowth or the burnt-out phase) results in better / more symmetric correction. This study sought to quantify pre- and post-operative facial asymmetry in UCH patients comparing treatment for active versus burnt out disease. METHODS: Pre- and post-operative three-dimensional (3D) photographs were obtained. Images were compared to unaffected controls as a standard for normal facial symmetry. Facial asymmetry was assessed using root mean squared deviation (RMSD). Paired student's t-tests were performed to compare the RMSDs of pre- and post-operative images between the UCH groups and against controls. RESULTS: Forty patients were included (11 active, 9 burnt-out, and 20 controls) and 60 3D images were evaluated. Pre-operatively, patients in the burnt-out group had worse asymmetry than those with active UCH (p = 0.011). Both groups demonstrated significantly improved symmetry post-operatively (active; p = 0.0069 and burnt out; p = 1.74E-4). However, burnt out patients remained with some residual asymmetry (p = 4.75E-4), while their active counterparts showed no significant difference compared to unaffected controls (p = 0.089). CONCLUSION: Patients with end-stage UCH have more severe facial asymmetry that is more difficult to normalize, compared to earlier intervention during active UCH. These findings suggest that, if possible, corrective intervention is preferable during active UCH.

Plast Reconstr Surg ; 145(4): 944-946, 2020 04.
Artículo en Inglés | MEDLINE | ID: mdl-32221210


Treatment of nasal deformity and obstruction requires analysis, planning, and precise execution of rhinoplasty techniques. When performed well, rhinoplasty is a powerful tool for achieving appealing nasal morphology and optimizing function. This article aims to highlight an open approach to septorhinoplasty using a number of techniques that are preferred by the senior author (D.M.S.) to successfully correct a congenital nasal deformity and deviated septum.

Tabique Nasal/cirugía , Nariz/anomalías , Rinoplastia/métodos , Insatisfacción Corporal/psicología , Técnicas Cosméticas , Estética , Femenino , Humanos , Cuidados Intraoperatorios , Modelos Anatómicos , Adulto Joven
J Craniofac Surg ; 30(8): 2601-2603, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31449227


Correction of facial asymmetry caused by active unilateral condylar hyperplasia (CH) requires proper diagnosis, arrested ongoing condylar growth, and ultimately orthognathic surgery. Traditionally, prior to performing orthognathic surgery, active CH is addressed either by: awaiting natural cessation of condylar overgrowth, or performing an interval high condylectomy (to stop growth). However, these strategies both add to the total treatment time, by either waiting and confirming no active growth, or performing a first stage growth-arresting procedure. In this report, the authors describe concurrent high condylectomy, and 3-jaw orthognathic surgery, to address the root of the problem and provide aesthetic correction in the same setting. This clinical series illustrates a detailed description of this approach, highlighting operative order, and an analysis of outcomes.

Asimetría Facial/cirugía , Mandíbula/cirugía , Procedimientos Quirúrgicos Ortognáticos , Adolescente , Adulto , Femenino , Humanos , Cóndilo Mandibular/cirugía , Persona de Mediana Edad , Procedimientos Quirúrgicos Ortognáticos/métodos , Adulto Joven
J Craniofac Surg ; 29(3): 584-593, 2018 May.
Artículo en Inglés | MEDLINE | ID: mdl-29461365


Alveolar cleft reconstruction has historically relied on autologous iliac crest bone grafting (ICBG), but donor site morbidity, pain, and prolonged hospitalization have prompted the search for bone graft substitutes. The authors evaluated bone graft substitutes with the highest levels of evidence, and highlight the products that show promise in alveolar cleft repair and in maxillary augmentation. This comprehensive review guides the craniofacial surgeon toward safe and informed utilization of biomaterials in the alveolar cleft.A literature search was performed to identify in vitro human studies that fulfilled the following criteria: Level I or Level II of evidence, ≥30 subjects, and a direct comparison between a autologous bone graft and a bone graft substitute. A second literature search was performed that captured all studies, regardless of level of evidence, which evaluated bone graft substitutes for alveolar cleft repair or alveolar augmentation for dental implants. Adverse events for each of these products were tabulated as well.Sixteen studies featuring 6 bone graft substitutes: hydroxyapatite, demineralized bone matrix (DBM), ß-tricalcium phosphate (TCP), calcium phosphate, recombinant human bone morphogenic protein-2 (rhBMP-2), and rhBMP7 fit the inclusion criteria for the first search. Through our second search, the authors found that DBM, TCP, rhBMP-2, and rhBMP7 have been studied most extensively in the alveolar cleft literature, though frequently in studies using less rigorous methodology (Level III evidence or below). rhBMP-2 was the best studied and showed comparable efficacy to ICBG in terms of volume of bone regeneration, bone density, and capacity to accommodate tooth eruption within the graft site. Pricing for products ranged from $290 to $3110 per 5 mL.The balance between innovation and safety is a complex process requiring constant vigilance and evaluation. Here, the authors profile several bone graft substitutes that demonstrate the most promise in alveolar cleft reconstruction.

Proceso Alveolar/cirugía , Materiales Biocompatibles/uso terapéutico , Fisura del Paladar/cirugía , Procedimientos Quirúrgicos Reconstructivos/métodos , Ingeniería de Tejidos/métodos , Proceso Alveolar/anomalías , Autoinjertos , Proteína Morfogenética Ósea 2/uso terapéutico , Proteína Morfogenética Ósea 7/uso terapéutico , Regeneración Ósea , Sustitutos de Huesos/uso terapéutico , Trasplante Óseo , Fosfatos de Calcio/uso terapéutico , Durapatita/uso terapéutico , Humanos , Maxilar , Proteínas Recombinantes/uso terapéutico , Factor de Crecimiento Transformador beta/uso terapéutico , Trasplante Autólogo