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1.
J Environ Manage ; 319: 115647, 2022 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-35803069

RESUMEN

Olive mill wastewater (OMW) resulting from the olive oil extraction process is usually disposed of in evaporation ponds where it concentrates generating a sludge that pollutes the ponds nearby area. In this study, four bio-treatments were applied for the in-situ bioremediation and valorization of OMW sludge: Landfarming, phytoremediation, composting and vermicomposting. In all cases, the OMW sludge was added with organic residues (mushroom compost, rabbit manure, and chicken manure). The bio-treatments were carried out in duplicate, inoculated and non-inoculated, to determine the effect of a specialized fungal consortium (Aspergillus ochraceus H2 and Scedosporium apiospermum H16) on the efficacy of the bio-treatments. The evaluation of chemical parameters, toxicity, and functional microbial biodiversity revealed that the four techniques depleted the toxicity and favored the stimulation of functional microbiota. Landfarming and phytoremediation allowed the decontamination and improvement of soils. Composting and vermicomposting also offered high-quality products of agronomic interest. Inoculation improved the bioremediation effectiveness. Biological treatments are effective for the safe recovery of contaminated OMW sludge into high-quality services and products.


Asunto(s)
Olea , Aguas del Alcantarillado , Animales , Residuos Industriales/análisis , Estiércol , Olea/química , Aceite de Oliva , Estanques , Conejos , Aguas del Alcantarillado/microbiología , Eliminación de Residuos Líquidos/métodos , Aguas Residuales
2.
Nanotechnology ; 32(9): 095202, 2021 Feb 26.
Artículo en Inglés | MEDLINE | ID: mdl-33126229

RESUMEN

Solution-processed photodetectors have emerged as the next generation of sensing technology owing to their ease of integration with electron devices and of tuning photodetector performance. Currently, novel self-powered photodetectors without an external power source, for use in sensing, imaging and communication, are in high demand. Herein, we successfully developed a self-powered photodetector based on a novel solution-processed p-NiO/n-CdS:Al heterojunction, which shows an excellent current rectification characteristic ratio of up to three orders in the dark and distinctive photovoltaic behavior under light illumination. The complete solution synthesis route followed the development of CdS:Al thin films on ITO substrates by chemical bath deposition and NiO thin films by the sol-gel route. Optical absorption data revealed that NiO is more active in the UV region and CdS:Al has a majority of absorption in the visible region; so, upon light illumination, the effective separation of photogenerated carriers produces fast photodetection in the UV-visible region. The photoresponsivity values of the fabricated device were calculated to be 55 mA W-1 and 30 mA W-1 for UV and visible illumination, respectively. Also, the device has a fast rise and decay photoresponse speed at zero bias voltage, due to the self-driven photovoltaic effect which makes this heterojunction a self-powered device. This complete solution and new method of fabrication make it possible to combine different materials and flexible substrates, enhancing its potential applications in photodetectors, optoelectronic devices and sensors.

3.
Neuropathol Appl Neurobiol ; 47(1): 96-107, 2021 02.
Artículo en Inglés | MEDLINE | ID: mdl-32603552

RESUMEN

AIMS: Neurofibromatosis 1 (NF1) is an autosomal-dominant cancer predisposition syndrome caused by loss of function alterations involving the NF1 locus on chromosome 17. The most common brain tumours encountered in affected patients are low-grade gliomas (pilocytic astrocytomas), although high-grade gliomas are also observed at increased frequency. While bi-allelic NF1 loss characterizes these tumours, previous studies have suggested noncoding RNA molecules (microRNA, miR) may have important roles in dictating glioma biology. METHODS: To explore the contributions of miRs in NF1-associated gliomas, we analysed five high-grade gliomas (NF1-HGG) and five PAs (NF1-PA) using global microRNA profiling with NanoString-based microarrays followed by functional experiments with glioma cell lines. RESULTS: miR-10b-5p, miR-135b-5p, miR-196a-5p, miR-196b-5p, miR-1247-5p and miR-320a (adjusted P < 0.05) were increased> 3-fold in NF1-HGG relative to NF1-PA tumours. In addition, miR-378b and miR-1305 were decreased 6.8- and 6-fold, respectively, whereas miR-451a was increased 2.7-fold (adjusted P < 0.05) in NF1-PAs compared to non-neoplastic NF1 patient brain specimens (n = 2). As miR-10b-5p was the microRNA overexpressed the most in NF1-high-grade glioma compared to NF1-low-grade glioma (5.76 fold), we examined its levels in glioma cell lines. miR-10b-5p levels were highest in adult glioma cell lines and lowest in paediatric low-grade glioma lines (P = 0.02). miR-10b-5p knockdown resulted in decreased invasion in NF1-deficient LN229 high-grade glioma line, whereas its overexpression in the NF1-PA derived line (JHH-NF1-PA1) led to increased invasion. There was no change in cell growth (viability and proliferation). CONCLUSIONS: These proof-of-concept experiments support a role for microRNA regulation in NF1-glioma biology.


Asunto(s)
Glioma/genética , Glioma/patología , MicroARNs/genética , Neurofibromatosis 1/genética , Apoptosis/genética , Neoplasias Encefálicas/genética , Neoplasias Encefálicas/patología , Movimiento Celular/genética , Movimiento Celular/fisiología , Proliferación Celular/genética , Regulación Neoplásica de la Expresión Génica/genética , Humanos , Neurofibromatosis 1/patología
4.
J Hazard Mater ; 402: 123481, 2021 01 15.
Artículo en Inglés | MEDLINE | ID: mdl-32736177

RESUMEN

During the last two decades, the method most widely used to manage olive mill wastewater (OMW) derived from olive oil production has been its disposal in evaporation ponds. Long-term storage of OMW leads to the accumulation of toxic sediments (OMWS) rich in recalcitrant compounds with phytotoxic and antimicrobial properties, which limit their use for agronomic purpose. The aim of this study was to compare the effect of two in situ bioremediation strategies (composting and a combination of composting followed by vermicomposting) to remove the potential toxicity of the sediments derived from long-term stored OMW. The results obtained showed that the composting method assisted with the earthworms enhanced the depletion of phenolic compounds and OMWS ecotoxicity more than composting, especially during the maturation stage. Moreover, vermicomposting was more effective in the reduction of the OMWS salinity. However, a pre-composting process to the OMWS is necessary prior to vermicomposting to provide the suitable conditions for earthworms survival and activity. Furthermore, the final compost showed a phytostimulating effect. Therefore, these in situ bioremediation strategies can be considered potential tools for decontamination and recovery of long-term stored OMWS in evaporation ponds, which currently poses an unsolved environmental problem.


Asunto(s)
Compostaje , Olea , Biodegradación Ambiental , Residuos Industriales/análisis , Aceite de Oliva , Estanques , Eliminación de Residuos Líquidos , Aguas Residuales
5.
Rev Clin Esp ; 2020 Jun 27.
Artículo en Inglés, Español | MEDLINE | ID: mdl-32600570

RESUMEN

Deep vein thrombosis (DVT) is part of the clinical spectrum of venous thromboembolism disease (VTE), whose estimated annual incidence rate is 1-2 episodes per 1000 individuals and represents the third leading cause of cardiovascular mortality in developed countries. Establishing an accurate diagnosis of DVT is essential for preventing acute complications (such as pulmonary embolism) and chronic complications associated with post-thrombotic syndrome. Currently, there are well-established diagnostic algorithms for lower extremity DVT, which include clinical probability models that help establish the risk of experiencing the disease based on the patients' history, clinical findings, D dimer measurements, fibrin degradation product tests with a high negative predictive value and imaging tests to confirm the diagnosis. Venous compression ultrasonography is currently the technique of choice because it is a non-invasive, easy-to-administer test that can make serial evaluations. There is much accumulated evidence that DVT can be safely ruled out in patients with a low or intermediate clinical probability and a negative D dimer (<500 ng/mL) without performing additional examinations. The consensus is not as clear about the need for a proximal or complete examination of the entire extremity. Other techniques may also be employed, such as magnetic resonance venography and venous phase computed axial tomography, although these should not be a substitute for compression ultrasonography as the initial diagnostic test. There are other special circumstances in which the diagnosis is more problematic and there are no diagnostic algorithms as consolidated, such as DVT during pregnancy, diagnosing rethrombosis and DVT that affects the upper extremities.

6.
Materials (Basel) ; 13(3)2020 Feb 05.
Artículo en Inglés | MEDLINE | ID: mdl-32033379

RESUMEN

The effect of α-Al2O3 nanoparticles (up to 5 wt.%) on the physical, mechanical, and thermal properties, as well as on the microstructural evolution of a dense magnesia refractory is studied. Sintering temperatures at 1300, 1500, and 1600 °C are used. The physical properties of interest were bulk density and apparent porosity, which were evaluated by the Archimedes method. Thermal properties were examined by differential scanning calorimetry. The mechanical behavior was studied by cold crushing strength and microhardness tests. Finally, the microstructure and mineralogical qualitative characteristics were studied by scanning electron microscopy and X-ray diffraction, respectively. Increasing the sintering temperature resulted in improved density and reduced apparent porosity. However, as the α-Al2O3 nanoparticle content increased, the density and microhardness decreased. Microstructural observations showed that the presence of α-Al2O3 nanoparticles in the magnesia matrix induced the magnesium-aluminate spinel formation (MgAl2O4), which improved the mechanical resistance most significantly at 1500 °C.

7.
Appl Ergon ; 82: 102981, 2020 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-31670156

RESUMEN

In the present research, models based on multivariate adaptive regression splines (MARS) are proposed to study the influence of gender in the factors affecting the development of shoulders, neck and upper limb MSD. Two different MARS models, corresponding to men and women, are constructed to identify variables with the strongest effect on the target MSD. Both models are capable to predict successfully the occurrence of the studied disorders. Men seem to be more vulnerable to physical risk factors and some other working conditions, whereas women appear to be more affected by psychosocial risk factors and activities carried out outside their working hours. According to the results, gender needs to be considered to ensure the success and effectiveness of ergonomic interventions on the whole working population.


Asunto(s)
Enfermedades Musculoesqueléticas/fisiopatología , Cuello/fisiopatología , Enfermedades Profesionales/fisiopatología , Hombro/fisiopatología , Extremidad Superior/fisiopatología , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Persona de Mediana Edad , Análisis Multivariante , Factores de Riesgo , Factores Sexuales , Encuestas y Cuestionarios
8.
Sci Rep ; 9(1): 17772, 2019 Nov 28.
Artículo en Inglés | MEDLINE | ID: mdl-31780693

RESUMEN

We identify different schemes to enhance the violation of Leggett-Garg inequalities in open many-body systems. Considering a nonequilibrium archetypical setup of quantum transport, we show that particle interactions control the direction and amplitude of maximal violation, and that in the strongly-interacting and strongly-driven regime bulk dephasing enhances the violation. Through an analytical study of a minimal model we unravel the basic ingredients to explain this decoherence-enhanced quantumness, illustrating that such an effect emerges in a wide variety of systems.

9.
Acta Ortop Mex ; 33(4): 256-260, 2019.
Artículo en Español | MEDLINE | ID: mdl-32246598

RESUMEN

BACKGROUNDS: The isolated fracture/dislocation of the cuneiform bones is a not very frequent event and only a few cases have been reported in the literature. This type of event is presented as a variation of the Lisfranc injuries. The present report shows a rare clinical case of a patient with dislocation of the first and second cuneiform bones and fracture in situ of the third cuneiform bone of the left foot. CASE REPORT: A 49-year-old female patient presented severe traumatism of the dorsum of the foot with bony and soft tissue exposure as a result of a car accident. The patient underwent surgery in the emergency department consisting of surgical cleaning, debridement, reduction of dislocation of the first and second cuneiform bones and percutaneous fixation with 2.0 mm Kirschner wires. RESULTS: After the surgery, the patient was found to be in good general condition, oriented without pain, stable, conscious, without traces of active bleeding from the wound and with the presence of Kirschner wires in an appropriate position. DISCUSSION: An exhaustive inspection of the injury is recommended through the analysis of X-ray images, CT scans or magnetic resonance imaging, especially in unexposed lesions in order to apply the appropriate treatment and be able to achieve a prompt recovery of the patient.


ANTECEDENTES: La fractura y la luxación aislada de los huesos cuneiformes son un evento no muy frecuente y sólo pocos casos han sido reportados en la literatura. Este tipo de eventos se presenta como una variación de las lesiones de Lisfranc. El presente reporte muestra un caso clínico poco frecuente de un paciente con luxación de la primera y segunda cuña y fractura in situ de la tercera cuña del pie izquierdo. CASO CLÍNICO: Mujer de 49 años de edad, que presentó traumatismo severo del dorso del pie con exposición de tejido óseo y blando como consecuencia de atropellamiento. La paciente fue sometida a cirugía en el Servicio de Urgencias, donde se realizó aseo quirúrgico, desbridamiento, reducción de la luxación de la primera y segunda cuña y fijación percutánea con clavillos Kirschner de 2.0 mm. RESULTADOS: Posterior a la cirugía, la paciente se reportó con buen estado en general, orientada, sin facie de dolor, estable, consciente, sin huellas de sangrado activo por la herida y con presencia de clavillos Kirschner en adecuada posición. DISCUSIÓN: Se recomienda una inspección exhaustiva de la lesión a través del análisis de las imágenes de rayos X, tomografía computarizada o imágenes de resonancia magnética, especialmente en lesiones no expuestas, pues con ello se puede aplicar el tratamiento adecuado y lograr una pronta recuperación del paciente.


Asunto(s)
Fracturas Óseas , Luxaciones Articulares , Huesos Tarsianos , Hilos Ortopédicos , Femenino , Pie , Fracturas Óseas/cirugía , Humanos , Luxaciones Articulares/cirugía , Persona de Mediana Edad , Huesos Tarsianos/lesiones
12.
Opt Express ; 25(9): 10255-10260, 2017 May 01.
Artículo en Inglés | MEDLINE | ID: mdl-28468398

RESUMEN

We demonstrate a graphene-based electro-absorption modulator with extremely small modulation volume that can be controlled by low gating voltages 1-3 V and shows light modulation at wavelengths as short as 900 nm. Our choice of hafnium oxide dielectric separator gives the possibility to obtain significant electro-optical effect in a simple optical heterostructure. Having low power consumption, our devices could find a wide range of applications in telecom industry.

13.
Rev. mex. ing. bioméd ; 38(1): 13-24, ene.-abr. 2017. tab, graf
Artículo en Español | LILACS-Express | LILACS | ID: biblio-902325

RESUMEN

Resumen: La existencia de una correlación entre la frecuencia cardíaca (FC), la frecuencia respiratoria (FR) y las respuestas electrodérmicas de la piel (Skin Conductance Response, SCR) ha sido reportada en la literatura, así como también el uso de estos parámetros como medida del nivel de activación del sistema nervioso autónomo. Objetivo: Este trabajo presenta una herramienta (SCRATER) para el análisis conjunto de SCR, FC y FR, las dos últimas, calculadas a partir del análisis del registro de electrocardiograma (ECG). Metodología: En esta investigación, se realizó una descripción detallada de cada algoritmo desarrollado, asi como una una descripción de la interfaz para utilizarlos. En la validación de los algoritmos empleados, se analizaron 192 registros de ECG y 231 registros de actividad electrodérmica (Electro-Dermal Activity, EDA) de 40 participantes masculinos sanos, de los cuales se calculó el número de complejos QRS y FC en cada registro de ECG y el número de SCRs de cada registro de EDA. Resultados: Los datos obtenidos fueron comparados con otras herramientas que analizan SCR y FC pero de manera independiente, obteniendo resultados equiparables mediante coeficientes de correlación. Limitaciones: El ruido y los artefactos presentes en los registros no permiten una correcta estimación de los parámetros y afectan los resultados de todas las herramientas empleadas en el desarrollo de este trabajo. Valor: SCRATER ofrece tres ventajas principales sobre las otras herramientas: 1) libre acceso, 2) código abierto y no utiliza formatos codificados o exclusivos. Conclusión: Este trabajo proporciona una herramienta computacional gratuita que permite analizar simultáneamente SCRs, FC y FR.


Abstract: The existence of a correlation between heart rate (HR), respiratory rate (RR) and skin conductance response (SCR) has been reported in the literature, as well as the use of these parameters as a measure of the activation level of the autonomous nervous system. Objective: This paper introduces a computational tool (SCRATER) developed with the aim to analyze simultaneous recordings of SCR, and heart and respiratory rates, which were calculated from the electrocardiogram recording (ECG) analysis. Methodology: In this research, a detailed description of each developed algorithm was made, as well as a description of the interface to be used. In the validation of the algorithms used, 192 ECG records and 231 Electro-Dermal Activity (EDA) registers of 40 healthy male participants were analyzed, from which the number of QRS complexes and HR in each ECG record and the number of SCRs of each EDA record are calculated. Results: The data obtained were compared with other tools that analyze SCR and HR separately, obtaining comparable results using correlation coefficients. Limitations: The noise and artifacts present in the records do not allow a correct estimation of the parameters and affect the results of all the tools used in the development of this work. Value: SCRATER offers three main advantages over other tools: 1) free access, 2) open source and 3) does not use coded or exclusive formats. Conclusion: This work provides a free computational tool that allows simultaneous analysis of SCRs, FC and FR.

14.
Pharmacopsychiatry ; 50(1): 38-40, 2017 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-27414740

RESUMEN

Introduction: Paliperidone palmitate treatment of schizophrenia or schizoaffective disorder is effective and well tolerated, but there is almost no data on its safety during pregnancy. Case report: An analysis is made of the safety and tolerability of paliperidone palmitate treatment throughout the gestation period in a 34-year-old patient diagnosed with schizoaffective disorder. Discussion: Paliperidone palmitate treatment throughout the gestation period was safe and well tolerated by both mother and foetus, there being no malformations or other perinatal complications in the newborn to date.


Asunto(s)
Antipsicóticos/efectos adversos , Palmitato de Paliperidona/efectos adversos , Efectos Tardíos de la Exposición Prenatal/inducido químicamente , Trastornos Psicóticos/tratamiento farmacológico , Adulto , Femenino , Humanos , Embarazo , Resultado del Tratamiento
15.
Nat Commun ; 7: 13590, 2016 11 22.
Artículo en Inglés | MEDLINE | ID: mdl-27874003

RESUMEN

Two-dimensional atomic heterostructures combined with metallic nanostructures allow one to realize strong light-matter interactions. Metallic nanostructures possess plasmonic resonances that can be modulated by graphene gating. In particular, spectrally narrow plasmon resonances potentially allow for very high graphene-enabled modulation depth. However, the modulation depths achieved with this approach have so far been low and the modulation wavelength range limited. Here we demonstrate a device in which a graphene/hexagonal boron nitride heterostructure is suspended over a gold nanostripe array. A gate voltage across these devices alters the location of the two-dimensional crystals, creating strong optical modulation of its reflection spectra at multiple wavelengths: in ultraviolet Fabry-Perot resonances, in visible and near-infrared diffraction-coupled plasmonic resonances and in the mid-infrared range of hexagonal boron nitride's upper Reststrahlen band. Devices can be extremely subwavelength in thickness and exhibit compact and truly broadband modulation of optical signals using heterostructures of two-dimensional materials.

18.
Nat Commun ; 6: 8846, 2015 Nov 10.
Artículo en Inglés | MEDLINE | ID: mdl-26554944

RESUMEN

The unique optical and electronic properties of graphene make possible the fabrication of novel optoelectronic devices. One of the most exciting graphene characteristics is the tunability by gating which allows one to realize active optical devices. While several types of graphene-based photonic modulators have already been demonstrated, the potential of combining the versatility of graphene with subwavelength field confinement of plasmonic waveguides remains largely unexplored. Here we report fabrication and study of hybrid graphene-plasmonic waveguide modulators. We consider several types of modulators and identify the most promising one for telecom applications. The modulator working at the telecom range is demonstrated, showing a modulation depth of >0.03 dB µm(-1) at low gating voltages for an active device area of just 10 µm(2), characteristics which are already comparable to those of silicon-based waveguide modulators while retaining the benefit of further device miniaturization. Our proof-of-concept results pave the way towards on-chip realization of efficient graphene-based active plasmonic waveguide devices for optical communications.

19.
J Thromb Haemost ; 13(7): 1274-8, 2015 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-25980766

RESUMEN

BACKGROUND: No studies have identified which patients with upper-extremity deep vein thrombosis (DVT) are at low risk for adverse events within the first week of therapy. METHODS: We used data from Registro Informatizado de la Enfermedad TromboEmbólica to explore in patients with upper-extremity DVT a prognostic score that correctly identified patients with lower limb DVT at low risk for pulmonary embolism, major bleeding, or death within the first week. RESULTS: As of December 2014, 1135 outpatients with upper-extremity DVT were recruited. Of these, 515 (45%) were treated at home. During the first week, three patients (0.26%) experienced pulmonary embolism, two (0.18%) had major bleeding, and four (0.35%) died. We assigned 1 point to patients with chronic heart failure, creatinine clearance levels 30-60 mL min(-1) , recent bleeding, abnormal platelet count, recent immobility, or cancer without metastases; 2 points to those with metastatic cancer; and 3 points to those with creatinine clearance levels < 30 mL min(-1) . Overall, 759 (67%) patients scored ≤ 1 point and were considered to be at low risk. The rate of the composite outcome within the first week was 0.26% (95% confidence interval [CI] 0.004-0.87) in patients at low risk and 1.86% (95% CI 0.81-3.68) in the remaining patients. C-statistics was 0.73 (95% CI 0.57-0.88). Net reclassification improvement was 22%, and integrated discrimination improvement was 0.0055. CONCLUSIONS: Using six easily available variables, we identified outpatients with upper-extremity DVT at low risk for adverse events within the first week. These data may help to safely treat more patients at home.


Asunto(s)
Técnicas de Apoyo para la Decisión , Pacientes Ambulatorios , Embolia Pulmonar/etiología , Trombosis Venosa Profunda de la Extremidad Superior/etiología , Adulto , Anciano , Anticoagulantes/efectos adversos , Canadá , Europa (Continente) , Femenino , Hemorragia/inducido químicamente , Humanos , Israel , Masculino , Persona de Mediana Edad , Valor Predictivo de las Pruebas , Embolia Pulmonar/diagnóstico , Embolia Pulmonar/mortalidad , Embolia Pulmonar/prevención & control , Sistema de Registros , Medición de Riesgo , Factores de Riesgo , América del Sur , Factores de Tiempo , Resultado del Tratamiento , Trombosis Venosa Profunda de la Extremidad Superior/diagnóstico , Trombosis Venosa Profunda de la Extremidad Superior/mortalidad , Trombosis Venosa Profunda de la Extremidad Superior/terapia
20.
Diaeta (B. Aires) ; 33(151): 14-20, abril. 2015. graf
Artículo en Español | LILACS | ID: lil-766759

RESUMEN

El consumo de suplementos nutricionales (SN) se ha investigado generalmente en relación al rendimiento deportivo. Menos información existe en relación a población no deportista pero físicamente activa. Objetivo y metodología: El objetivo fue conocer las características de los consumidores de SN en 412 usuarios (179 mujeres) de gimnasios de cuatro ciudades del sur de Chile. El instrumento utilizado para recolectar datos correspondió a un cuestionario previamente validado (1), estructurado con preguntas cerradas, alternativas y preguntas abiertas en relación al consumo de SN. Para su interpretación se utilizaron estadísticos descriptivos y de comparación (i.e. Chi cuadrado). El nivel de significancia estadística se estableció en p<0,05. Resultados: los resultados revelan que 22% de los usuarios consumen SN. De los hombres consumidores, 37% lo realiza para aumentar masa muscular y 36% para mejorar el rendimiento físico. Entre las mujeres, 32% los consume por motivos relacionados a salud. Los SN más consumidos fueron: proteínas (36%), vitaminas y minerales (11%), creatina (10%), aminoácidos y carbohidratos (8%). En cuanto al perfil del consumidor, está representado por jóvenes de entre 15 a 25 años, dedicados en su mayoría al estudio y al trabajo, con menos de un año de asistencia al gimnasio y una frecuencia de asistencia ≥ 3 sesiones/semana. Conclusión: un relativamente bajo consumo de SN fue observado,en comparación con deportistas, influenciado por la edad,el género y el uso de dieta o alimentación especial. Varones jóvenes (i.e. 15 a 25 años de edad) que trabajan, con una alta frecuencia de asistencia a gimnasios (≥ 3 sesiones/semana) son los principales consumidores de SN...


Asunto(s)
Humanos , Chile , Dieta , Suplementos Dietéticos , Gimnasia
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