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Diabetes Metab Syndr ; 13(5): 2827-2832, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31425943


AIMS: Determine the correlation of quality of life (QoL) and the impact on the metabolic control of patients with type 2 diabetes mellitus (T2DM). METHODS: An observational study was conducted at the outpatient consulting service in a specialized hospital in Santo Domingo, DR. We used a non-probabilistic, convenience sampling strategy, and the World Health Organization Quality of Life (WHOQOL-BREF) short form questionnaire was applied. RESULTS: The patients presented lower impact in QoL domains was: pain (x¯=29.07, SD = 3.04) and negative feelings (x¯=28.70, SD = 3.33). We found there is a negative correlation between the psychological domains and the fasting glycemia (rho = -0.192, p < 0.05), also between the summary of all domains of QoL and metabolic control, HbA1C (rho = -0.205, p < 0.05), and fasting glycaemia (rho = -0.214, p < 0.05). There was a significant difference in the physical domains F (1, 131) = 9.73, p = 0.002, η2 = 0.069, indicating that men (M = 14.81) have a higher physical QoL than women (M = 13.72). CONCLUSION: Given the evidence of the impact of metabolic control and the different domains to QoL, it is necessary to consider these aspects in the treatment plan of patients with diabetes, to ensure adequate management and control of future complications.

Biomarcadores/análisis , Diabetes Mellitus Tipo 2/tratamiento farmacológico , Índice Glucémico , Indicadores de Salud , Síndrome Metabólico/prevención & control , Calidad de Vida , Adulto , Anciano , Anciano de 80 o más Años , Glucemia/análisis , Diabetes Mellitus Tipo 2/diagnóstico , Diabetes Mellitus Tipo 2/epidemiología , Diabetes Mellitus Tipo 2/metabolismo , Femenino , Estudios de Seguimiento , Hemoglobina A Glucada/análisis , Humanos , Hipoglucemiantes/uso terapéutico , Masculino , Síndrome Metabólico/epidemiología , Persona de Mediana Edad , Pronóstico , Encuestas y Cuestionarios , Organización Mundial de la Salud
Trans R Soc Trop Med Hyg ; 113(6): 293-297, 2019 06 01.
Artículo en Inglés | MEDLINE | ID: mdl-30892643


BACKGROUND: Human immunodeficiency virus (HIV) increases the risk of acquiring human T-cell lymphotropic virus (HTLV) and subsequently HTLV's progression to tropical spastic paraparesis/HTLV-1-associated myelopathy (TSP/HAM). Existing data have exclusively reported generalized rates of HIV and HTLV-1 chronic viral infections in the Dominican Republic. To our knowledge, no published studies have focused on the rates of HTLV-1/2 in transactional sex workers and drug users, both higher risk groups, in the Dominican Republic. METHODS: From December 2012 to April 2013 we conducted a study to estimate the seroprevalence of HTLV-1/2 immunoglobulin G (IgG) and HIV antibodies among transactional sex workers and intravenous drug users in Santo Domingo, Dominican Republic. Serological status was analysed with behaviour and demographic data. RESULTS: We collected and analysed plasma from 200 participants with a mean age of 27.4 y in men and 25.2 y in women. The overall weighted seroprevalence of HTLV-1/2 IgG antibodies was 13.91% (95% CI 7.59 to 20.23) in men and 10.59% (95% CI 4.05 to 17.13) in women. The overall weighted seroprevalence of HIV-1 was 13.91% (95% CI 7.59 to 20.23%) in men and 17.65% (95% CI 9.55 to 25.75) in women. Male intravenous drug users had an exceptionally high rate of HTLV-positive HIV co-infection, at 75% (95% CI 44.99 to 105.01). Although there an association has been found between HTLV/HIV co-infections and sex work, the adjusted odds revealed a confounding role of HIV infection. CONCLUSIONS: The results highlight the urgent need for enhanced public health preventive strategies among high-risk populations in the Dominican Republic and other resource-constrained Caribbean settings, as well as global adoption of routine screening for HTLV-associated infections, particularly in these high-risk, underserved populations.

Diabetes Metab Syndr ; 13(1): 576-580, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-30641769


AIMS: The quality of life (QoL) of patients with diabetes and in hemodialysis is affected by their nutritional status. We aimed to determine the correlation between QoL and nutritional status of patients in hemodialysis. METHODS: We conducted a study with people with diabetes and in hemodialysis. We used Kidney Disease and Quality of Life-Short form (KDQOL-SFTM) scale to evaluate QoL and the Subjective Global Assessment (SGA) questionnaire for nutritional evaluation. RESULTS: The studied patients, 71.43% were over 55 years old and 81% of participants were male. The domain of QoL must impaired were cognitive function (x¯=26.35, SD = 20.81) and interaction of social quality (x¯=19.32, SD = 17.24). The characteristics that most favorably impacted QoL were dialysis equipment support (x¯=83.93, SD = 20.59) and patient satisfaction (x¯=86.51, SD = 17.17). The undernourished patients were 56.6% (n = 14). There was a strong lineal relationship between the Physical and Mental Health Composite and nutritional status, Spearman rank (rho = 0.935, p = <0.001), (rho=0.926, p = <0.001) respectively. CONCLUSION: There is a strong relationship between QoL and nutritional status, ensuring that a good nutritional status could positively influence QoL.

Diabetes Mellitus/psicología , Fallo Renal Crónico/psicología , Estado Nutricional/fisiología , Calidad de Vida/psicología , Diálisis Renal/psicología , Anciano , Diabetes Mellitus/diagnóstico , Diabetes Mellitus/terapia , Femenino , Humanos , Fallo Renal Crónico/diagnóstico , Fallo Renal Crónico/terapia , Masculino , Persona de Mediana Edad , Diálisis Renal/tendencias