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4.
Case Rep Cardiol ; 2019: 9027029, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31885934

RESUMEN

Brugada syndrome (BrS) is a genetic condition that accentuates the risk of potentially lethal ventricular arrhythmias and sudden cardiac death (SCD) in a structurally normal heart. The Brugada electrocardiographic pattern may manifest separately from the syndrome-this clinical scenario has been described as Brugada phenocopy (BrP). Many etiologies of BrP have been reported, but it has not yet been reported as a result of coronary slow flow (CSF) phenomenon. This case report highlights a suspected coronary slow flow-associated Brugada type 1 electrocardiographic pattern, which subsequently normalized following the institution of guideline-directed medical therapy for acute coronary syndrome.

5.
Clin Med (Lond) ; 19(6): 528-529, 2019 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-31732600

RESUMEN

QRS electrical alternans is characterised by alternating amplitude of the QRS complexes, and is well-documented in cardiac conditions such as pericardial effusion. We describe a case of QRS alternans in a patient with gastric volvulus.


Asunto(s)
Vólvulo Gástrico , Dolor Abdominal/etiología , Anciano de 80 o más Años , Electrocardiografía , Femenino , Hernia Hiatal/complicaciones , Humanos , Vólvulo Gástrico/complicaciones , Vólvulo Gástrico/diagnóstico , Vólvulo Gástrico/fisiopatología , Taquicardia/complicaciones , Tórax/diagnóstico por imagen
6.
9.
Ann Intern Med ; 169(10): 737-738, 2018 11 20.
Artículo en Inglés | MEDLINE | ID: mdl-30452567
14.
Am J Cardiol ; 121(6): 715-717, 2018 03 15.
Artículo en Inglés | MEDLINE | ID: mdl-29397883

RESUMEN

Brugada phenocopies (BrPs) are clinical entities that differ in etiology from true congenital Brugada syndrome but have identical electrocardiographic (ECG) patterns. Hyperkalemia is known to be one of the causes of BrP. The aim of this study was to determine the clinical characteristics and evolution of hyperkalemia-induced BrP. Data from 27 cases of hyperkalemia-induced BrP were collected from the International Registry at www.brugadaphenocopy.com. Data were extracted from publications. Of the 27 patients included in the analysis, 18 (67%) were male; mean age was 53 ± 15 years (range 31 to 89). Mean serum potassium concentration was 7.45 ± 0.89 mmol/L. Type-1 Brugada ECG pattern was observed in 21 cases (78%), whereas 6 cases (22%) showed a type-2 Brugada ECG pattern. The Brugada ECG pattern resolved once the hyperkalemia was corrected, with no arrhythmic events. Estimated time to resolution was 7 ± 3 hours. In 4 cases (16%), a concurrent metabolic abnormality was detected: 3 (11%) presented with acidosis, 2 (7%) with hyponatremia, 1 (4%) with hypocalcaemia, 1 (4%) with hyperphosphatemia, and 1 (4%) with hyperglycemia. In 7 cases (26%), provocative testing using sodium channel blockers was performed, and all failed to reproduce a BrS ECG pattern (BrP class A). Additionally, no sudden cardiac death or malignant ventricular arrhythmias were detected. Hyperkalemia was found a common cause of BrP in our International Registry. The Brugada ECG pattern appears to occur at high serum potassium concentrations (>6.5 mmol/L). The ECG normalizes within hours of correcting the electrolyte imbalance. Importantly, hyperkalemia-induced BrP has not been associated with sudden cardiac death or ventricular arrhythmia.


Asunto(s)
Síndrome de Brugada/etiología , Síndrome de Brugada/fisiopatología , Electrocardiografía , Hiperpotasemia/complicaciones , Hiperpotasemia/fisiopatología , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Hiperpotasemia/tratamiento farmacológico , Masculino , Persona de Mediana Edad , Fenotipo , Sistema de Registros
15.
Clin Dermatol ; 36(1): 14-20, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-29241747

RESUMEN

The metabolic syndrome-otherwise called syndrome X, insulin resistance syndrome, Reaven syndrome, and "the deadly quartet"-is the name given to the aggregate of clinical conditions comprising central and abdominal obesity, systemic hypertension, insulin resistance (or type 2 diabetes mellitus), and atherogenic dyslipidemia. It is a prothrombotic and proinflammatory state characterized by increased inflammatory cytokine activity. In addition to inflammatory dermatoses such as psoriasis, lichen planus, and hidradenitis suppurativa, metabolic syndrome is also commonly associated with accelerated atherosclerotic cardiovascular disease, hyperuricemia/gout, chronic kidney disease, and obstructive sleep apnea. Current therapeutic options for metabolic syndrome are limited to individual treatments for hypertension, hyperglycemia, and hypertriglyceridemia, as well as dietary control measures and regular exercise.


Asunto(s)
Inflamación/metabolismo , Resistencia a la Insulina , Síndrome Metabólico/epidemiología , Síndrome Metabólico/fisiopatología , Citocinas/metabolismo , Humanos , Inflamación/complicaciones , Síndrome Metabólico/etiología , Obesidad Abdominal/complicaciones , Estrés Oxidativo
19.
Am J Emerg Med ; 32(1): 111.e1, 2014 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-24054851

RESUMEN

We discuss a 72-year-old woman admitted with acute shortness of breath and severe sharp chest pain several hours after receiving acupuncture therapy. She was subsequently diagnosed as having an iatrogenic pneumothorax secondary to acupuncture. We discuss the complications of acupuncture and why patients should be informed of the risks of such procedures.


Asunto(s)
Analgesia por Acupuntura/efectos adversos , Neumotórax/etiología , Anciano , Dolor en el Pecho/etiología , Disnea/etiología , Servicio de Urgencia en Hospital , Femenino , Humanos , Neumotórax/diagnóstico , Neumotórax/diagnóstico por imagen , Radiografía
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