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1.
Kardiologiia ; 59(10S): 31-40, 2019 Jul 23.
Artículo en Ruso | MEDLINE | ID: mdl-31876460

RESUMEN

Purpos. To assess the effectiveness of preventive counseling with focus on diet modification followed by remote support via telephone on awareness of cardiovascular (CV) risk factors (RFs) in patients (pts) with high/very high CV risk. Material and methods. This is a prospective randomized controlled study of 100 pts with high/very high CV risk (5-9% and ≥10% according to the SCORE scale) and any 2 criteria for metabolic syndrome.  Pts were randomized into 2 groups in 1:1 ratio - the intervention group (n=50) and the control group (n=50). The intervention group received comprehensive preventive counseling with focus on diet modification followed by remote preventive counseling by phone every two weeks for the first 3 months after enrollment (a total of 6 sessions). The control group received usual care in Health centers which also included basic preventive counseling. A specially designed questionnaire was used to evaluate the awareness of the basic CV RFs, including open questions. The awareness was assessed at baseline, 6 and 12 months. Results. The groups were well balanced according to demographic and clinical features. The results of the study revealed an extremely low awareness of major CV RFs of pts in both groups at baseline: practically none of them indicated as RFs for cardiovascular disease elevated cholesterol (8,0% and 4,0%, respectively) and blood pressure (14.0% and 4.0%). At 6 month the level of awareness of CV RFs has increased significantly. Moreover, pts of the intervention group were more informed about elevated cholesterol (58,0% vs. 28,0%; p<0,01) and unhealthy diet (76,0% vs. 52,0%; p<0,05). At 12 month the level of awareness of CV RFs was significantly higher in both groups  to compare from baseline. Conclusion. Preventive counseling with focus on diet modification followed by 3 months  remote support via phone provided a significant improvement of awareness of CV RFs in pts with high/very high CV risk.


Asunto(s)
Enfermedades Cardiovasculares , Presión Sanguínea , Consejo , Humanos , Estudios Prospectivos , Factores de Riesgo
2.
Kardiologiia ; 59(7S): 4-14, 2019 Aug 22.
Artículo en Ruso | MEDLINE | ID: mdl-31441736

RESUMEN

The role of nutrition in the development and progression of atherosclerosis is well known. The correction of diet in patients with dyslipidemia is important as an independent intervention (in the group of patients with low and, partially, moderate cardiovascular risk), and as an addition to drug therapy in patients with at higher risk of cardiovascular events. The current review describes the effect of modern methods of diet therapy, as well as the use of a number of nutraceutical agents in terms of evidence-based medicine.


Asunto(s)
Aterosclerosis , Dislipidemias , Dieta , Suplementos Dietéticos , Humanos , Estado Nutricional
3.
Kardiologiia ; (10): 71-79, 2018 Oct.
Artículo en Ruso | MEDLINE | ID: mdl-30359218

RESUMEN

The article describes the definition of dementia, its diagnostic criteria, classification. Differences in the pathogenesis and clinical manifestations of different types of dementia are considered. The issues of interrelation of arterial hypertension and the risk of development of cognitive disorders and dementia in old and very old people are discussed in detail. Data on the effect of antihypertensive drugs of different groups on the risk of dementia and the state of cognitive functions are presented. The evidence base of dihydropyridine calcium antagonist amlodipine and thiazide-like diuretic indapamide-retard is discussed with respect to the prevention of dementia and cognitive decline and their beneficial effect on cognitive function in patients with arterial hypertension.


Asunto(s)
Demencia , Hipertensión , Indapamida , Antihipertensivos , Presión Sanguínea , Cognición , Humanos
4.
Ter Arkh ; 89(8): 88-94, 2017.
Artículo en Ruso | MEDLINE | ID: mdl-28914857

RESUMEN

Glycogen storage disease (GSD) is an inherited metabolic disorder characterized by early childhood lipid metabolic disturbances with potentially proatherogenic effects. The review outlines the characteristics of impaired lipid composition and other changes in the cardiovascular system in GSD types I and III. It analyzes the factors enabling and inhibiting the development of atherosclerosis in patients with GSD. The review describes the paradox of vascular resistance to the development of early atherosclerosis despite the proatherogenic composition of lipids in the patients of this group.


Asunto(s)
Sistema Cardiovascular , Enfermedad del Almacenamiento de Glucógeno Tipo III , Enfermedad del Almacenamiento de Glucógeno Tipo I , Metabolismo de los Lípidos , Aterosclerosis/etiología , Aterosclerosis/metabolismo , Sistema Cardiovascular/metabolismo , Sistema Cardiovascular/fisiopatología , Enfermedad del Almacenamiento de Glucógeno Tipo I/complicaciones , Enfermedad del Almacenamiento de Glucógeno Tipo I/metabolismo , Enfermedad del Almacenamiento de Glucógeno Tipo I/fisiopatología , Enfermedad del Almacenamiento de Glucógeno Tipo III/complicaciones , Enfermedad del Almacenamiento de Glucógeno Tipo III/metabolismo , Enfermedad del Almacenamiento de Glucógeno Tipo III/fisiopatología , Humanos , Resistencia Vascular
5.
Stomatologiia (Mosk) ; 96(2): 75-78, 2017.
Artículo en Ruso | MEDLINE | ID: mdl-28514353

RESUMEN

The article describes a structural element of natural teeth - mantle dentin. It has been shown that the presence of this element in the structure of a natural tooth largely ensures its strength under the influence of repeated loads in a functional oral environment and arrests crack growth at the enamel/dentine interface. This later effect is explained by the influence of a thin layer of mantle dentine, which has physical and mechanical characteristics different from that of the main dentin.


Asunto(s)
Esmalte Dental/lesiones , Esmalte Dental/ultraestructura , Materiales Dentales , Restauración Dental Permanente/métodos , Dentina/ultraestructura , Modelos Biológicos , Módulo de Elasticidad , Dureza , Humanos
6.
Kardiologiia ; 54(5): 34-8, 2014.
Artículo en Ruso | MEDLINE | ID: mdl-25177885

RESUMEN

The article is devoted to assessment of pulse pressure (PP) in female postmenopausal patients and patients with arterial hypertension (AH) older than 55 years. It is shown that in postmenopausal women even aged 55 years or less PP is one of most important parameters associated with target organ damage. Conclusion about presence of elevated vascular wall stiffness in these women as in elderly patients can be made at PP more or equal 60 mm Hg. In elderly patients both with isolated systolic AP and 1-2 degree systolic-diastolic monotherapy with indapamide 1,5 mg retard allows not only to achieve clear-cut hypotensive effect but in both variants of AH to lower PP. This can substantially decrease degree of cardiovascular risk without crossing bottom borders of diastolic AP lowering. The latter is especially important for elderly patients with isolated systolic AH.


Asunto(s)
Presión Sanguínea/efectos de los fármacos , Hipertensión , Indapamida/administración & dosificación , Análisis de la Onda del Pulso/métodos , Rigidez Vascular/efectos de los fármacos , Factores de Edad , Anciano , Antihipertensivos/administración & dosificación , Femenino , Humanos , Hipertensión/tratamiento farmacológico , Hipertensión/epidemiología , Hipertensión/fisiopatología , Masculino , Persona de Mediana Edad , Pronóstico , Factores de Riesgo , Factores Sexuales , Resultado del Tratamiento
7.
Vopr Pitan ; 80(3): 18-24, 2011.
Artículo en Ruso | MEDLINE | ID: mdl-21842749

RESUMEN

The role of dietary and hereditary factors in the development of metabolic syndrome is discussed in this review.


Asunto(s)
Dieta/efectos adversos , Síndrome Metabólico/genética , Síndrome Metabólico/fisiopatología , Humanos
8.
Vopr Pitan ; 80(3): 53-6, 2011.
Artículo en Ruso | MEDLINE | ID: mdl-21842756

RESUMEN

Determine what in women in early age exceptionally on artificial nutrition risk beginning insulin resistance and breach carbohydrate metabolism more high than in women receive in pectoral age naturally nutrition. This relation especially distinctly reveals in women with obesity.


Asunto(s)
Lactancia Materna , Metabolismo de los Hidratos de Carbono , Resistencia a la Insulina , Adolescente , Adulto , Femenino , Humanos , Fórmulas Infantiles , Recién Nacido , Obesidad/etiología , Obesidad/metabolismo
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