Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 33
Filtrar
Más filtros










Base de datos
Intervalo de año de publicación
1.
HLA ; 2020 Sep 14.
Artículo en Inglés | MEDLINE | ID: mdl-32926547

RESUMEN

Characterization of two novel HLA-DQA1*03:03:01 variants, HLA-DQA1*03:03:01:13 and -DQA1*03:03:01:14.

2.
HLA ; 2020 Jun 30.
Artículo en Inglés | MEDLINE | ID: mdl-32602620

RESUMEN

Characterization of two novel HLA-DPA1*02:01:01 variants, HLA-DPA1*02:01:01:18 and -DPA1*02:01:01:19.

3.
HLA ; 2020 Jul 05.
Artículo en Inglés | MEDLINE | ID: mdl-32627390

RESUMEN

Characterization of three novel HLA-DQB1*05 variants, HLA-DQB1*05:01:01:08, -DQB1*05:02:01:07 and -DQB1*05:03:01:05.

4.
HLA ; 2020 Jul 02.
Artículo en Inglés | MEDLINE | ID: mdl-32614137

RESUMEN

Identification of the HLA-DQB1*02:02:13 that differs from HLA-DQB1*02:02:01:01 by a synonymous substitution in exon 2. This article is protected by copyright. All rights reserved.

5.
HLA ; 2020 Jun 14.
Artículo en Inglés | MEDLINE | ID: mdl-32536005

RESUMEN

Identification of the first HLA-DQB1*03:04:01 variant, called HLA-DQB1*03:04:01:02.

6.
HLA ; 96(3): 361-362, 2020 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-32584514

RESUMEN

Characterization of five novel HLA-DQA1*01 variants, HLA-DQA1*01:01:01:08, -DQA1*01:02:01:14, -DQA1*01:02:02:05, -DQA1*01:03:01:10 and -DQA1*01:05:01:03.

7.
HLA ; 96(3): 268-276, 2020 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-32424903

RESUMEN

HLA genes can exhibit extensive variations in frequency, especially in highly admixed populations, such as that of Brazil. In this study, we demonstrated NGS-based HLA typing in our laboratory using an Illumina HiSeq 2500 sequencing platform and downstream analysis. We herein describe and compare the allele and haplotype frequencies of the populations in Barra Mansa (BM) and Rio de Janeiro (RJ), using the acquired genetic data. Sequences encompassing 7 HLA loci (HLA-A, HLA-B, HLA-C, HLA-DRB1, HLA-DQB1, HLA-DPA1, and HLA-DPB1) were amplified from a total of 1435 bone marrow samples donated by volunteers recruited in BM (37.56%) and RJ (62.44%) using polymerase chain reactions, and were sequenced using five distinct HiSeq 2500 runs. Alleles were analyzed to generate 2-locus haplotypes and extended haplotypes encompassing more than two loci. The most frequent haplotype was A*01:01:01~C*07:01:01~B*08:01:01~DRB1*03:01:01~DQB1*02:01:01~DPA1*01:03:01~DPB1*04:01:01 in both populations. The populations of BM and RJ exhibited a significant difference in genetic composition (P = .03) but not in genetic variance (P = .45). However, some groups of subjects, classified based on self-declared ethnicity, particularly Branca and Preta, displayed significant genetic variance (P < .05). In conclusion, these genetic data indicate no differences in HLA loci between the populations of these two cities, but were informative with respect to variations in ancestry composition.

8.
HLA ; 96(1): 115-116, 2020 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-32248663

RESUMEN

Identification of the first HLA-DQA1*01:01:02 variant, called HLA-DQA1*01:01:02:02.

9.
HLA ; 96(3): 355-356, 2020 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-32246525

RESUMEN

Identification of the HLA-C*17:51:02 that differs from HLA-C*17:51:01:01 by a synonymous substitution in exon 5.

10.
HLA ; 96(1): 89-90, 2020 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-32026608

RESUMEN

Identification of the novel HLA-A*02:916 allele that differs from HLA-A*02:01:01:01 in exon 5.

11.
HLA ; 96(1): 90-91, 2020 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-32034896

RESUMEN

Identification of the novel HLA-A*31:177 allele that differs from HLA-A*31:01:02:04 in exon 5.

12.
HLA ; 95(6): 587-588, 2020 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-31981322

RESUMEN

Characterization of two novel HLA-DQB1*06:02:01 variants, HLA-DQB1*06:02:01:05 and -DQB1*06:02:01:06.

13.
HLA ; 95(3): 228-229, 2020 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-31758852

RESUMEN

Identification of the novel HLA-DQA1*02:11 allele that differs from HLA-DQA1*02:01:01:01 in exon 2.

14.
HLA ; 95(3): 208-209, 2020 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-31749306

RESUMEN

Identification of the novel HLA-A*30:162 allele that differs from HLA-A*30:02:01:01 in exon 3.

15.
HLA ; 95(2): 141-142, 2020 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-31628782

RESUMEN

Characterization of an HLA-C*04:01:01 variant, HLA-C*04:01:01:76.

16.
HLA ; 95(6): 586-587, 2020 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-31837118

RESUMEN

Characterization of two novel HLA-DQB1*05:01:01 variants, HLA-DQB1*05:01:01:06 and DQB1*05:01:01:07.

17.
HLA ; 95(2): 153-154, 2020 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-31664783

RESUMEN

Characterization and confirmation of an HLA-DQA1*04:01:01 variant, HLA-DQA1*04:01:01:09.

18.
HLA ; 95(1): 75-76, 2020 01.
Artículo en Inglés | MEDLINE | ID: mdl-31587516

RESUMEN

Characterization of two novel HLA-DQA1*05:05:01 variants, HLA-DQA1*05:05:01:22 and -DQA1*05:05:01:23.

19.
HLA ; 95(1): 84-85, 2020 01.
Artículo en Inglés | MEDLINE | ID: mdl-31589362

RESUMEN

Characterization of three novel HLA-DPA1*02:01:01 variants: HLA-DPA1*02:01:01:14, -DPA1*02:01:01:15, and -DPA1*02:01:01:16.

20.
HLA ; 95(1): 55-56, 2020 01.
Artículo en Inglés | MEDLINE | ID: mdl-31596039

RESUMEN

Characterization of an HLA-C*03:04:01 variant, HLA-C*03:04:01:39.

SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA