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1.
Artículo en Inglés | MEDLINE | ID: mdl-32367376

RESUMEN

INTRODUCTION: The reverse homodigital dorsoradial flap remains a useful alternative for covering thumb defects. However, the description of pedicle width of dorsoradial flap is not clear. The aim of this study was to compare the results of narrow pedicle with wide pedicle in dorsoradial flaps and describe our experience with the thumb reconstruction. MATERIALS AND METHODS: From July 2014 to February 2019, 42 patients were treated with the reverse dorsoradial flap for thumb reconstruction. The patients were divided as Group A (pedicle width ≤ 0.8 cm) and Group B (pedicle width > 0.8 cm). Flap survival, time to return to work, flap sensibility, the range of motion (ROM) of the joints, and final aesthetic outcomes were evaluated. RESULTS: Respectively in the Group A (17 cases) and Group B (25 cases), 14-19 flaps survived uneventfully, whereas 3-6 flaps experienced venous congestion with no or partial flap loss. No significant difference was identified between the two groups for the incidence of venous congestion, static 2-point discrimination and ROM of the injured thumbs. Time to return to work was significantly shorter in Group A. The aesthetic satisfaction of the patients in Group A was significantly better comparing with that in Group B. CONCLUSIONS: The reverse homodigital dorsoradial flap with narrow pedicle width is associated with more favorable outcomes in terms of time lost from work and aesthetic satisfaction of the patients.

2.
Methods Mol Biol ; 2117: 293-303, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-31960388

RESUMEN

Arsenic is a well-known human carcinogen. However, the mechanisms underlying arsenic-induced carcinogenesis remain elusive. Here we show that chronic and low level of arsenic stress induces transformation of the human bronchial epithelial cells, BEAS-2B, and that some of the transformed cells show characteristics of cancer stem-like cells (CSCs). Meanwhile, we demonstrate that arsenic stress dedifferentiates CD61+ BEAS-2B cells into CSC-like CD61- cells featured with noncanonical epithelial-mesenchymal transition (EMT), enhanced chemoresistance, and metastasis. Finally, we show that oncogene c-Myc expression is associated with arsenic-induced tumor initiation and progression. Altogether, our findings highlight a unique mechanism of arsenic-induced transformation of human bronchial epithelial cells and provide a novel therapeutic target for arsenic-initiated lung cancer.

3.
Colloids Surf B Biointerfaces ; 185: 110590, 2020 Jan 01.
Artículo en Inglés | MEDLINE | ID: mdl-31670002

RESUMEN

Since low pH value is widely observed in most of solid tumors, pH-responsive drug delivery system (DDS) can provide a general strategy for tumor-targeting therapy. In this work, a traceable and pH-responsive DDS (MoS2-PEG-DOX) based on MoS2 quantum dots (MoS2 QDs) is successfully developed by covalently grafting MoS2 QDs with diamine-terminated oligomeric polyethylene glycol (PEG) and then loading with a fluorescent antineoplastic anthracycline drug, doxorubicin (DOX). The functionalization of MoS2 QDs with PEG imparts the nanocomposite with strong blue photoluminescence, low cytotoxicity, and excellent physiological stability. The MoS2-PEG-DOX nano-assembly can be effectively taken up by U251 cells, and an accelerated DOX release is then triggered by intracellular acid condition, which in turn diminishing unwanted side effects derived by the incorporation of DOX into healthy cells. Meanwhile, the cellular uptake of the MoS2-PEG-DOX nano-assembly, consequent DOX release and the localization of nanocarrier can be real-time monitored due to the inherent stable fluorescence of MoS2-PEG and DOX. These findings demonstrate that MoS2-PEG-DOX will be promising for high treatment efficacy with minimal side effects in future therapy.

4.
Phys Rev Lett ; 123(7): 073001, 2019 Aug 16.
Artículo en Inglés | MEDLINE | ID: mdl-31491105

RESUMEN

We generate high-fidelity massively entangled states in an antiferromagnetic spin-1 Bose-Einstein condensate (BEC) by utilizing multilevel oscillations. Combining the multilevel oscillations with additional adiabatic drives, we greatly shorten the necessary evolution time and relax the requirement on the control accuracy of quadratic Zeeman splitting, from microgauss to milligauss, for a ^{23}Na spinor BEC. The achieved high fidelities over 96% show that two kinds of massively entangled states, the many-body singlet state and the twin-Fock state, are almost perfectly generated. The generalized spin squeezing parameter drops to a value far below the standard quantum limit even with the presence of atom number fluctuations and stray magnetic fields, illustrating the robustness of our protocol under real experimental conditions. The generated many-body entangled states can be employed to achieve the Heisenberg-limit quantum precision measurement and to attack nonclassical problems in quantum information science.

5.
Environ Sci Technol ; 53(13): 7306-7315, 2019 07 02.
Artículo en Inglés | MEDLINE | ID: mdl-31244060

RESUMEN

Atmospheric chemical transport models (CTMs) have been widely used to simulate spatiotemporally resolved PM2.5 concentrations. However, CTM results are usually prone to bias and errors. In this study, we improved the accuracy of PM2.5 predictions by developing an ensemble deep learning framework to fuse model simulations with ground-level observations. The framework encompasses four machine-learning models, i.e., general linear model, fully connected neural network, random forest, and gradient boosting machine, and combines them by stacking approach. This framework is applied to PM2.5 concentrations simulated by the Community Multiscale Air Quality (CMAQ) model for China from 2014 to 2017, which has complete spatial coverage over the entirety of China at a 12-km resolution, with no sampling biases. The fused PM2.5 concentration fields were evaluated by comparing with an independent network of observations. The R2 values increased from 0.39 to 0.64, and the RMSE values decreased from 33.7 µg/m3 to 24.8 µg/m3. According to the fused data, the percentage of Chinese population residing under the level II National Ambient Air Quality Standards of 35 µg/m3 for PM2.5 has increased from 46.5% in 2014 to 61.7% in 2017. The method is readily adapted to utilize near-real-time observations for operational analyses and forecasting of pollutant concentrations and can be extended to provide source apportionment forecasts as well.


Asunto(s)
Contaminantes Atmosféricos , Contaminación del Aire , China , Aprendizaje Profundo , Monitoreo del Ambiente , Material Particulado
6.
Phys Rev Lett ; 122(1): 010408, 2019 Jan 11.
Artículo en Inglés | MEDLINE | ID: mdl-31012664

RESUMEN

Dynamical decoupling (DD) is an active and effective method for suppressing decoherence of a quantum system from its environment. In contrast to the nominal biaxial DD, this work presents a uniaxial decoupling protocol that requires a significantly reduced number of pulses and a much lower bias field satisfying the "magic" condition. We show this uniaxial DD protocol works effectively in a number of model systems of practical interest, e.g., a spinor atomic Bose-Einstein condensate in stray magnetic fields (classical noise), or an electron spin coupled to nuclear spins (quantum noise) in a semiconductor quantum dot. It requires only half the number of control pulses and a 10-100 times lower bias field for decoupling as normally employed in the above mentioned illustrative examples, and the overall efficacy is robust against rotation errors of the control pulses. The uniaxial DD protocol we propose shines new light on coherent controls in quantum computing and quantum information processing, quantum metrology, and low field nuclear magnetic resonance.

7.
3 Biotech ; 8(7): 313, 2018 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-30023145

RESUMEN

Phosphate (PO43-) accumulation associated with bacteria contributes to efficient remediation of eutrophic waters and has attracted attention due to its low cost, high removal efficiency and environmental friendliness. In the present study, we isolated six strains from sludge with high concentrations of chemical oxygen demand, total nitrogen and total phosphorus levels. Among them, strain LH4 exhibited the greatest PO43- removal ability. Strain LH4 is typical of Acinetobacter junii based on physiological, biochemical, and molecular analyses and is a PO43--accumulating organism (PAO) based on toluidine blue staining. The strain grew quickly when subjected to aerobic medium after pre-incubation under anaerobic condition, with a maximum OD600 of 1.429 after 8 h and PO43- removal efficiency of 99%. Our data also indicated that this strain preferred utilizing the carbon (C) sources sodium formate and sodium acetate and the nitrogen (N) sources NH4Cl and (NH4)2SO4 over other compounds. To achieve optimal PO43- removal efficiency, a C:N ratio of 5:1, inoculation concentration of 3%, solution pH of 6, incubation temperature of 30 °C, and shaking speed of 100 rpm were recommended for A. junii strain LH4. By incubating this strain with different concentrations of PO43-, we calculated that its relative PO43- removal capacity ranged from 0.67 to 3.84 mg L-1 h-1, ranking in the top three among reported PAOs. Our study provided a new PO43--accumulating bacterial strain that holds promise for remediating eutrophic waters, and its potential for large-scale use warrants further investigation.

8.
Sci Rep ; 7(1): 14102, 2017 10 26.
Artículo en Inglés | MEDLINE | ID: mdl-29074937

RESUMEN

We investigate the process of spin squeezing in a ferromagnetic dipolar spin-1 Bose-Einstein condensate under the driven one-axis twisting scheme, with emphasis on the detrimental effect of noisy environments (stray magnetic fields) which completely destroy the spin squeezing. By applying concatenated dynamical decoupling pulse sequences with a moderate bias magnetic field to suppress the effect of the noisy environments, we faithfully reconstruct the spin squeezing process under realistic experimental conditions. Our noise-resistant method is ready to be employed to generate the spin squeezed state in a dipolar spin-1 Bose-Einstein condensate and paves a feasible way to the Heisenberg-limit quantum metrology.

9.
J Bone Miner Metab ; 35(3): 289-297, 2017 May.
Artículo en Inglés | MEDLINE | ID: mdl-27023332

RESUMEN

The relationship between hip fracture risk and opioid use remains controversial. Thus, we performed a meta-analysis to assess the risk of hip fracture among opioid users. PubMed and EMBASE were searched for studies published from the inception of the databases until June 2015. The information was extracted independently by two teams of authors. When the heterogeneity was significant, the random-effects model was used to calculate the overall pooled risk estimates. Ten studies with 697,011 patients were included in the final meta-analysis. The overall combined relative risk for the use of opioids and hip fracture was 1.54 [95 % confidence interval (CI) 1.34-1.77]. Subgroup analyses revealed sources of heterogeneity, and sensitivity analysis indicated stable results, and no publication bias was observed. This meta-analysis demonstrates that opioids significantly increase the risk of hip fracture.


Asunto(s)
Analgésicos Opioides/efectos adversos , Fracturas de Cadera/inducido químicamente , Fracturas de Cadera/epidemiología , Trastornos Relacionados con Opioides/epidemiología , Anciano , Estudios de Cohortes , Humanos , Persona de Mediana Edad , Sesgo de Publicación , Factores de Riesgo
11.
J Cosmet Laser Ther ; 18(7): 389-392, 2016 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-27331875

RESUMEN

BACKGROUND: Pulsed dye laser (PDL) treatment remains the standard of care for infantile hemangiomas (IHs). However, the use of PDL to treat IHs in neonates has been hardly reported. In this study, the PDL treatments of IHs between neonatal and non-neonatal patients were retrospectively investigated. METHODS: All patients diagnosed with hemangiomas were treated by PDL. Their clinical data were collected, and the treatment outcomes and PDL parameters in neonates and non-neonates were analyzed using the Mann-Whitney U-rank test. RESULTS: All patients reached good or excellent scale in the treatment efficiency assessment. Laser energy used per treatment session was significantly lower in neonatal group than in non-neonatal group (Z = -8.980, P < 0.001). Total laser energy used in neonates was also markedly lower than that in non-neonatal patients (Z = -3.065, P = 0.002). However, treatment session numbers in these two groups were not significantly different (Z = -1.725, P = 0.085). Additionally, we observed that after each treatment, the purpura disappeared faster in neonates (2-4 weeks) than in non-neonatal patients (4-6 weeks), indicating neonates might have greater recovery ability. CONCLUSIONS: PDL, with distinct parameters, was effective in the treatment of IHs in neonates. After each laser treatment, neonates recovered faster than non-neonatal patients.


Asunto(s)
Hemangioma Capilar/cirugía , Hemangioma/cirugía , Láseres de Colorantes/uso terapéutico , Síndromes Neoplásicos Hereditarios/cirugía , Humanos , Lactante , Recién Nacido , Estudios Retrospectivos , Resultado del Tratamiento
12.
Intern Med ; 55(12): 1525-8, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-27301500

RESUMEN

Methods To investigate the safety and clinical significance of the method described in this study, we focused on 16 peritoneal dialysis patients with peritoneal dialysis (PD) catheter malposition and blockage in whom nonsurgical reposition was ineffective, who received a local incision about 5 cm below hypogastrium PD catheter insertions under local anesthesia. Tissues were separated layer by layer, 1-cm incisions were performed on the peritoneum vertically and conventionally, and then the PD catheters were pulled. Adherent mesentery was separated and the PD catheters were freed and removed sufficiently. PD catheters were introduced into the Dow cavity using large introducing forceps, were loop-ligated and fixed using 3# silk thread, and then the ligation line was sutured to the peritoneum. The tissues were managed layer by layer and the skin was sutured. All patients were followed up for half a year. Results Sixteen cases of refractory PD catheter malposition and blockage were managed successfully, with an operative incision of 3 cm and an operation time of 40±13 minutes. The localized anesthesia was well tolerated, and there were five cases in which lidocaine at 5 mg was added during the operation; postoperative pain was slight and only three patients used analgesics at night. All patients were treated with coagulation hemostasis, and there was no transfusion. No malposition, leakage or blockage was found at follow-up at more than six months. Conclusion It is safe, simple, inexpensive and associated with fewer complications to correct refractory PD catheter malposition and blockage by loop ligature and fixation through a minilaparotomy of inserted hypogastrium PD catheters promptly.


Asunto(s)
Catéteres de Permanencia/efectos adversos , Migración de Cuerpo Extraño/cirugía , Diálisis Peritoneal/efectos adversos , Adulto , Anciano , Cateterismo/efectos adversos , Cateterismo/métodos , Falla de Equipo , Femenino , Migración de Cuerpo Extraño/etiología , Humanos , Fallo Renal Crónico/terapia , Laparotomía/métodos , Masculino , Persona de Mediana Edad , Diálisis Peritoneal/instrumentación , Peritoneo/cirugía , Adulto Joven
13.
Asian Pac J Trop Med ; 9(3): 261-4, 2016 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-26972398

RESUMEN

OBJECTIVE: To discuss the effect of dimethyl fumarate (DMF) on rats with l-arginine induced chronic pancreatitis (CP). METHODS: Male Wistar rats were given DMF treatment (25 mg/kg) by oral lavage method; then Wistar rats were given the intraperitoneal injection of l-arginine for 5 times (250 mg/100 kg, twice per time, each interval of 1 h) for building of CP model. Rats were divided into control group, CP group, DMF group and CP + DMF group. Rats in CP + DMF group were given the oral intragastric administration of DMF (25 mg/kg), while rats in control group and CP group were given the equal volume of normal saline. The weight of rats was evaluated and the intraperitoneal glucose tolerance test was performed (IPGTT, 2 g/kg). The islet of rats was isolated and then flow cytometry was employed to evaluate the quality and activity of islets. Meanwhile, the histology of non-endocrine tissues and levels of myeloperoxidase (MPO) and malondialdehyde (MDA) were detected. RESULTS: Compared with control group, the weight of rats in CP group was significantly reduced at week 2, 4 and 6; the blood glucose significantly increased, AUC increased, the histopathological scores of pancreatic atrophy, acinar injury, edema and cellular infiltration increased, levels of MDA and MPO increased, the islet equivalent and islet activity decreased at 0, 30, 60, 120 and 180 min. Compared with CP group, the weight of rats in CP + DMF group significantly increased at week 2, 4 and 6; the blood glucose significantly decreased, AUC decreased, the histopathological scores of pancreatic atrophy, acinar injury, edema and cellular infiltration decreased, levels of MDA and MPO decreased, the islet equivalent and islet activity increased at 0, 30, 60, 120 and 180 min. CONCLUSIONS: DMF treatment can improve CP induced by l-arginine and islet function in rats.

15.
Proc Natl Acad Sci U S A ; 112(35): 10884-9, 2015 Sep 01.
Artículo en Inglés | MEDLINE | ID: mdl-26283358

RESUMEN

Integrating accurate air quality modeling with decision making is hampered by complex atmospheric physics and chemistry and its coupling with atmospheric transport. Existing approaches to model the physics and chemistry accurately lead to significant computational burdens in computing the response of atmospheric concentrations to changes in emissions profiles. By integrating a reduced form of a fully coupled atmospheric model within a unit commitment optimization model, we allow, for the first time to our knowledge, a fully dynamical approach toward electricity planning that accurately and rapidly minimizes both cost and health impacts. The reduced-form model captures the response of spatially resolved air pollutant concentrations to changes in electricity-generating plant emissions on an hourly basis with accuracy comparable to a comprehensive air quality model. The integrated model allows for the inclusion of human health impacts into cost-based decisions for power plant operation. We use the new capability in a case study of the state of Georgia over the years of 2004-2011, and show that a shift in utilization among existing power plants during selected hourly periods could have provided a health cost savings of $175.9 million dollars for an additional electricity generation cost of $83.6 million in 2007 US dollars (USD2007). The case study illustrates how air pollutant health impacts can be cost-effectively minimized by intelligently modulating power plant operations over multihour periods, without implementing additional emissions control technologies.


Asunto(s)
Contaminantes Ocupacionales del Aire/análisis , Electricidad , Salud Laboral , Técnicas de Planificación , Centrales Eléctricas , Contaminantes Ocupacionales del Aire/toxicidad , Georgia , Humanos
16.
PLoS One ; 10(6): e0129064, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-26053951

RESUMEN

OBJECTIVES: This study aimed to determine the HBV infection status of 135 patients with DLBCL (diffuse large B cell lymphoma), to analyze the overall survival (OS) and progression-free survival (PFS) of the different HBV infection status groups, and to discuss the relationship between HBV serological test results and the prognosis of DLBCL patients. METHODS: A retrospective analysis was performed of the clinical data, HBV serological test results, and PFS/OS of 135 DLBCL patients who were initially diagnosed and treated with more than 3 cycles of an R-CHOP/CHOP/CHOP-like regimen at our center from January 1, 2008 to December 31, 2012. RESULTS: The patients in the HBV infection group were older at disease onset (≥60 years old) and were more likely to present with stage 3-4 disease compared with the HBV-free group (P = 0.030 and P = 0.025, respectively). Approximately 50% of the patients with an active HBV infection required a reduction in the chemotherapy dose, and 66.7% of the patients in this group received more than 1 line of therapy; these rates were significantly higher than those in the no infection group (P = 0.003 and P = 0.011, respectively). Although HBV infection had no obvious influence on the outcome of first-line therapy, patients with an inactive infection had a higher relapse/progression rate within 3 months after a CR/PR than patients with an active infection (14/20 vs. 1/12, P = 0.001). The PFS at 1 year, 3 years and OS rates at 1 year, 3 years were significantly lower in the active HBV infection group than in the HBV-free group (P = 0.008, P = 0.002, P = 0.004, and P = 0.002, respectively). The PFS rates at 1 year and 3 year in HBV-free group were higher than those in the HBV infection group (80.5% and 52.9% P = 0.001, 78.1% and 44.4% P = 0.002). The lymphoma-related mortality rates were 2.7% in the no infection group, 19.2% in the HBV infection group (P = 0.004), and 28.6% in the active HBV infection group (P = 0.001). Among the patients treated with MabThera, the PFS in the HBV infection group was 11 months in the HBV infection group and 67 months in the infection-free group (P = 0.000). A Cox regression model of PFS revealed that age ≥60 years and HBV infection were independent prognostic factors (age: P = 0.019, HR = 2.002, 95% CI 1.123-3.567; HBV infection: P = 0.026, HR = 0.494, 95% CI 0.265-0.919). CONCLUSION: Compared with the patients in HBV-free group, those in the HBV infection group were older at disease onset, and the active infection patients presented with more advanced disease and had a lower PFS at 1, 3 years as well as a lower OS at 3 years. The patients in the inactive infection group had a higher progression/relapse rate within 3 months after a CR/PR than those in the active infection group. HBV infection was an unfavorable factor for PFS in the MabThera group. An age ≥60 years and HBV infection were independent unfavorable prognostic factors for PFS.


Asunto(s)
Hepatitis B/complicaciones , Hepatitis B/virología , Linfoma de Células B Grandes Difuso/complicaciones , Adulto , Anciano , Anciano de 80 o más Años , Anticuerpos Monoclonales de Origen Murino , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Ciclofosfamida , Doxorrubicina , Femenino , Humanos , Linfoma de Células B Grandes Difuso/diagnóstico , Linfoma de Células B Grandes Difuso/tratamiento farmacológico , Linfoma de Células B Grandes Difuso/mortalidad , Masculino , Persona de Mediana Edad , Estadificación de Neoplasias , Prednisona , Estudios Retrospectivos , Rituximab , Análisis de Supervivencia , Vincristina
17.
Environ Technol ; 35(21-24): 2813-20, 2014.
Artículo en Inglés | MEDLINE | ID: mdl-25176485

RESUMEN

Nitrogen (N) and phosphorus (P) are the two main factors causing water eutrophication. Immobilized micro-organisms have been widely studied in N and P removal. However, the effects of various immobilizing conditions on the removal efficiency of N and P using immobilized micro-organism beads (IMOBs) remain unclear. Polyvinyl alcohol (PVA) and alginate, as the two frequently immobilizing-used matrixes, were used for co-immobilizing Pseudomonas stutzeri YHA-13 and Alcaligenes sp. ZGED-12. PVA, alginate and CaCl2contents, immobilization time and different wet biomass ratios of P. stutzeri to Alcaligenes sp. were conducted to elucidate their roles in and influences on the removal efficiency of N and P from synthetic wastewater. The application potential of IMOBs was estimated as well. Results showed that IMOBs prepared by cross-link of 4% PVA and 2-3% alginate with 5% CaCl2and saturated boric acid solution for 10-15 min are the best ones in removal of N and P. Though IMOBs containing P. stutzeri and/or Alcaligenes sp. were capable of removal of the two nutrients, the highest removal efficiency was observed when the wet biomass ratio of P. stutzeri to Alcaligenes sp. was adjusted to 2:2. In addition, the IMOBs were of good ability to remove chemical oxygen demand (COD), NO(3)(-), NO(2)(-), NH(4)(+)- N, total nitrogen (TN) and total phosphorus (TP) from artificial wastewater. Of which, micro-organisms immobilized in matrixes were mainly responsible for NO(3)(-) and TP removal. Therefore, P. stutzeri YHA-13 and Alcaligenes sp. ZGED-12 are reliable bioresources to remove N and P from wastewater.


Asunto(s)
Alcaligenes/metabolismo , Alginatos , Alcohol Polivinílico , Pseudomonas stutzeri/metabolismo , Eliminación de Residuos Líquidos/métodos , Cloruro de Calcio , Ácido Glucurónico , Ácidos Hexurónicos , Nitrógeno/metabolismo , Fósforo/metabolismo , Contaminantes Químicos del Agua/metabolismo
18.
Nanoscale ; 6(17): 10134-9, 2014 Sep 07.
Artículo en Inglés | MEDLINE | ID: mdl-25042514

RESUMEN

We experimentally investigate the protection of electron spin coherence of a nitrogen-vacancy (NV) centre in diamond by dynamic nuclear spin polarization (DNP). The electron spin decoherence of an NV centre is caused by the magnetic field fluctuation of the (13)C nuclear spin bath, which contributes large thermal fluctuation to the centre electron spin when it is in an equilibrium state at room temperature. To address this issue, we continuously transfer the angular momentum from electron spin to nuclear spins, and pump the nuclear spin bath to a polarized state under the Hartmann-Hahn condition. The bath polarization effect is verified by the observation of prolongation of the electron spin coherence time (T). Optimal conditions for the DNP process, including the pumping pulse duration and repeat numbers, are proposed by numerical simulation and confirmed by experiment. We also studied the depolarization effect of laser pulses. Our results provide a new route for quantum information processing and quantum simulation using the polarized nuclear spin bath.

19.
Sci Rep ; 4: 5535, 2014 Jul 02.
Artículo en Inglés | MEDLINE | ID: mdl-24985708

RESUMEN

Majorana fermions are long-sought exotic particles that are their own antiparticles. Here we propose to utilize superconducting circuits to construct two superconducting-qubit arrays where Majorana modes can occur. A so-called Majorana qubit is encoded by using the unpaired Majorana modes, which emerge at the left and right ends of the chain in the Majorana-fermion representation. We also show this Majorana qubit in the spin representation and its advantage, over a single superconducting qubit, regarding quantum coherence. Moreover, we propose to use four superconducting qubits as the smallest system to demonstrate the braiding of Majorana modes and show how the states before and after braiding Majoranas can be discriminated.

20.
Wei Sheng Wu Xue Bao ; 53(1): 47-58, 2013 Jan 04.
Artículo en Chino | MEDLINE | ID: mdl-23614240

RESUMEN

OBJECTIVE: This study is aimed to isolate and identify an aerobic denitrifying bacterium with high ability for nitrogen removing, and optimize its growing and denitrifying conditions to obtain the theory basis for controlling the eutrophic artificial lake. METHODS: Aerobic denitrifying bacterium strain A-13 was screened by denitrifying medium. Strain identification was carried out through morphological, biochemical and physiological characteristics, 16S rRNA gene and periplasm nitrate reductase gene analysis. The optimal pH, temperature, carbon source, dissolved oxygen (DO), inoculum ratio were tested as well. RESULTS: Strain A-13 isolated from a drain outlet located in Gaoqi village, Shangjie town, Minhou county, Fuzhou, China, was a member of Pseudomonas stutzeri and its DNA sequence was most closely related to Pseudomonas stutzeri DSM 50283. The optimal conditions for its growth and denitrification were followed as: pH 6.5, 33 degrees C, 150 r/min, 5% inoculum rate and the best carbon source was sodium succinate. Under these conditions, the maximum removal capacity for NO3- was approximately 1900 mg/L. The strain could grow well in the medium with high salinity (10%) and could also use NO2- and NH(4+)-H as the sole nitrogen source. CONCLUSION: The isolated P. stutzeri, A-13 is a potential strain to treat wastewater with high salinity and/or eutrophication.


Asunto(s)
Bacterias Aerobias/aislamiento & purificación , Bacterias Aerobias/metabolismo , Aguas del Alcantarillado/microbiología , Cloruro de Sodio/metabolismo , Bacterias Aerobias/clasificación , Bacterias Aerobias/genética , China , Desnitrificación , Datos de Secuencia Molecular , Filogenia
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