Effectiveness of a Manual Therapy Protocol in Women with Pelvic Pain Due to Endometriosis: A Randomized Clinical Trial.

A randomized controlled trial was carried out to assess the effectiveness of a manual therapy protocol in terms of the clinical characteristics, quality of life, and emotional condition of the women with endometriosis-related pelvic pain. Forty-one women (mean age of 36.10 (6.97) years) with pelvic pain due to endometriosis were randomly divided into (i) a manual therapy group (MTG) (n = 21) and (ii) a placebo group (PG) (n = 20). Both groups received an 8-week intervention. Pain, lumbar mobility, endometriosis health profile, quality of life, depression and anxiety levels, and the patient's perception of change were assessed before (T0) and after (T1) the intervention, as well as at a one-month follow-up (T2) and a six-month follow-up (T3). The MTG significantly improved pain intensity, powerlessness, lumbar mobility, and physical quality of life at T1 (p < 0.05). The results were maintained for pain intensity at T2 and T3. In addition, both the MTG and PG improved emotional wellbeing at T1 (p < 0.05). Neither group improved in terms of social support, self-image, and depression and anxiety levels after the intervention (p > 0.05). In conclusion, manual therapy may be an excellent complement to the gynecological treatment of endometriosis-related pelvic pain by alleviating pain and improving women's endometriosis health profile and physical quality of life.

Can we hit prenatal depression and anxiety through HIIT? The effectiveness of online high intensity interval training in pregnant women during the COVID-19 pandemic: a randomized controlled trial.

BACKGROUND: In recent years high intensity interval training (HIIT) has grown in popularity. However, it rarely represents training interventions in experimental studies in pregnant populations. Therefore, in this study we aimed to assess changes in depressive symptoms, fear of childbirth, fear of Covid-19 and quality of life after an 8-week supervised online HIIT program, compared to an educational (self-performed physical activity) program. METHODS: We conducted a randomized control trial among 54 Caucasian women in uncomplicated, singleton pregnancy (age 32 ± 4 years, 22 ± 4 week of gestation; mean ± SD). There were 34 women in the experimental group, who participated in an 8-week high intensity interval training program (HIIT group). The comparative group was constituted of 20 pregnant women who attended 8-week educational program (EDU group). RESULTS: The most important finding was that mental health improved somewhat in both groups after the intervention, but only the HIIT group improved statistically significantly. The positive trends in lowering the severity of depressive symptoms, fear of childbirth, and fear of Covid-19 were observed in both groups. However, the positive response to the intervention was stronger in the EDU group. As a secondary outcome, there was a significant decrease in cardiorespiratory fitness level in the EDU group, while the HIIT group maintained unchanged level of maximal oxygen uptake. CONCLUSIONS: HIIT seems to be beneficial for women with uncomplicated pregnancies to maintain adequate quality of life and mental health. However, more research is needed to determine the effectiveness of prenatal HIIT in pregnant women in various psychological conditions. TRIAL REGISTRATION: We conducted this study in Poland, in 2021. It was approved by the Bioethics Commission at the District Medical Chamber in Gdansk (KB-8/21). The full study protocol was registered in ClinicalTrials.gov (NCT05009433).

[HOSPITAL EMPLOYEES IN THE COVID-19 PANDEMIC: WORKING CONDITIONS, LOYALTY AND EMOTIONAL STATE].

The spread of the new coronavirus infection (COVID-19) required dramatic changes in the healthcare system, the work of medical workers under extreme stress and an increased threat of infection. In order to formulate general recommendations for preventive work with employees in emergency conditions, a study was carried out of the current nature of work, the emotional state of medical workers and staff loyalty. In a multidisciplinary hospital in Moscow (City Clinical Hospital N 52) in the fall of 2020, a survey of hospital employees (595 people) was carried out according to the author's questionnaire with the additional use of the methodology for measuring the burnout syndrome index (MBI) and loyalty index (eNPS). A number of changes in the nature of work of medical workers were revealed, which had a significant impact on their emotional state, such as changes in the usual functionality, place and mode of work. Despite the negative aspects of working conditions, during the pandemic, the employee loyalty index remained quite high (eNPS = 24), doctors were the most loyal, and junior and middle staff were the least loyal. The assessment of the organizational aspects of the work as a whole was also quite high. The close connection between psychoemotional factors and the loyalty of the organization's employees was confirmed. The study made it possible to offer general recommendations for the development of preventive algorithms for working with employees in case of emergency.

THE OPTIMUM INTENSITY AND MODE OF COOLING DOWN PROCEDURES AFTER POST REPETITIVE INTERMITTENT HIGH-INTENSITY EXERCISE / 体力科学

The purpose of this study was to compare the effects derived from different modes of active cooling down procedures post repetitive intermittent high-intensity exercise. Seven Japanese male swimmers underwent repetitive 3 bouts of Wingate anaerobic tests on the 1^st day and another Wingate on the following 2^nd day. In each 3 intervals and post all the Wingate testing on the 2^nd day, the participants performed a cooling down randomly chosen from 3 different intensities of 10-min bike-riding and a 10-min static stretching. As to muscle power outputs and emotional conditions, the optimum cooling down intensities were observed at 80% ventilatoly threshold (VT) after the 1^st set and 60% VT level after the 2^nd set. Effective intensities of blood lactate removal rate were observed at 60% and 80% VT level. Thus, the optimum cooling down post repetitive intermittent high-intensity exercise could be dynamic bike-riding at 60% or 80% VT level.