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1.
HERD ; : 19375867241271435, 2024 Aug 16.
Artículo en Inglés | MEDLINE | ID: mdl-39150293

RESUMEN

Purpose: To present the social network analysis-based approach used to create a new workspace layout for three hospital services as part of a campus expansion at a large tertiary care public hospital. Objective: To analyze the relationships among service members across four healthcare resilience abilities (monitor, anticipate, respond, and learn) and utilize network metrics to indicate the suitability of a shared workspace layout for the services. Background: The hospital expanded by 70%, providing space for relocating key services-the rapid response team, medical on-call team, and nursing supervision. Initial observations suggested a shared workspace layout based on anecdotal evidence. Method: Stakeholders have reached a consensus on a three-stage process to assess the suitability of a shared workspace layout for these services: first, collecting data on social interactions with a focus on resilience abilities; second, presenting layout alternatives based on sociograms; and third, evaluating these alternatives and devising a strategy for allocating personnel to shifts based on a resilience score derived from social network metrics. Case Study: The examination of social network metrics allowed identifying key individuals contributing to the overall resilience of the three services. Sociograms provided visual representations of how these individuals were spatially distributed within the shared layout. Discussion: The process was designed to shape a resilient layout and incorporated initial data, preferences, and constraints into layout proposals. Additionally, it utilized a resilience score from existing literature to formulate a strategy for staff allocation to shifts, ensuring consistent collective resilience ability across all shifts.

2.
Int J Equity Health ; 23(1): 173, 2024 Aug 28.
Artículo en Inglés | MEDLINE | ID: mdl-39192277

RESUMEN

BACKGROUND: In China, retail pharmacies are critical sources for obtaining medications and play a vital role in residents' daily access to drugs and treatment of common illnesses. Effectively guiding the placement of these pharmacies in areas of need through government regulation is crucial for enhancing medication access. In this study, we used population and retail pharmacy spatial distribution data from Shanghai to design guidance and supplementary methods for optimizing the spatial layout of retail pharmacies and medical insurance designated pharmacies based on regional characteristics. METHODS: Population distribution, road traffic network, administrative division and retail pharmacy data from Shanghai in 2018 were collected from relevant government departments. ArcGIS 10.3 was used to map the retail pharmacies and population distribution. Based on the spatial distribution of population and the service standards of pharmacies, service circles with insufficient pharmacies were identified, and supplementary methods for retail pharmacies and medical insurance designated pharmacies were developed. RESULTS: In 2018, Shanghai had 3009 retail pharmacies, each serving an average of 6412 residents. The city was divided into 2188 basic pharmaceutical service circles, each within a 15-minute walking distance. The results indicated that there were 1387 service circles without any pharmacies, 151 of which had populations exceeding 5000. Additionally, 356 service circles had pharmacies but lacked medical insurance designated ones. After supplementation, 841 retail pharmacies were planned to be added in residential areas. Compared with before, the coverage area and population served of the pharmacies increased significantly. CONCLUSIONS: This study mapped the spatial distribution of population and retail pharmacies in Shanghai, and designed government guidance and supplementary methods for optimizing the layout of retail pharmacies. The findings offer valuable insights for government agencies in low- and middle-income countries to improve the spatial distribution of retail pharmacies.


Asunto(s)
Farmacias , China , Humanos , Farmacias/estadística & datos numéricos , Farmacias/normas , Regulación Gubernamental , Accesibilidad a los Servicios de Salud/estadística & datos numéricos , Accesibilidad a los Servicios de Salud/normas , Análisis Espacial
3.
Biomimetics (Basel) ; 9(8)2024 Jul 31.
Artículo en Inglés | MEDLINE | ID: mdl-39194441

RESUMEN

We propose a memory-enhanced multi-stage goal-driven network (ME-MGNet) for egocentric trajectory prediction in dynamic scenes. Our key idea is to build a scene layout memory inspired by human perception in order to transfer knowledge from prior experiences to the current scenario in a top-down manner. Specifically, given a test scene, we first perform scene-level matching based on our scene layout memory to retrieve trajectories from visually similar scenes in the training data. This is followed by trajectory-level matching and memory filtering to obtain a set of goal features. In addition, a multi-stage goal generator takes these goal features and uses a backward decoder to produce several stage goals. Finally, we integrate the above steps into a conditional autoencoder and a forward decoder to produce trajectory prediction results. Experiments on three public datasets, JAAD, PIE, and KITTI, and a new egocentric trajectory prediction dataset, Fuzhou DashCam (FZDC), validate the efficacy of the proposed method.

4.
Sensors (Basel) ; 24(16)2024 Aug 21.
Artículo en Inglés | MEDLINE | ID: mdl-39205086

RESUMEN

With the increasing aging of the global population, the efficiency and accuracy of the elderly monitoring system become crucial. In this paper, a sensor layout optimization method, the Fusion Genetic Gray Wolf Optimization (FGGWO) algorithm, is proposed which utilizes the global search capability of Genetic Algorithm (GA) and the local search capability of Gray Wolf Optimization algorithm (GWO) to improve the efficiency and accuracy of the sensor layout in elderly monitoring systems. It does so by optimizing the indoor infrared sensor layout in the elderly monitoring system to improve the efficiency and coverage of the sensor layout in the elderly monitoring system. Test results show that the FGGWO algorithm is superior to the single optimization algorithm in monitoring coverage, accuracy, and system efficiency. In addition, the algorithm is able to effectively avoid the local optimum problem commonly found in traditional methods and to reduce the number of sensors used, while maintaining high monitoring accuracy. The flexibility and adaptability of the algorithm bode well for its potential application in a wide range of intelligent surveillance scenarios. Future research will explore how deep learning techniques can be integrated into the FGGWO algorithm to further enhance the system's adaptive and real-time response capabilities.


Asunto(s)
Algoritmos , Rayos Infrarrojos , Humanos , Anciano , Monitoreo Fisiológico/métodos , Monitoreo Fisiológico/instrumentación
5.
Healthcare (Basel) ; 12(16)2024 Aug 21.
Artículo en Inglés | MEDLINE | ID: mdl-39201227

RESUMEN

Reasonably allocating medical resources can effsectively optimize the utilization efficiency of such resources. This paper took Taiyuan City as an example and established a model to evaluate the rationality of medical resource spatial allocation, incorporating two key dimensions: the spatial layout and the supply and demand of medical resources. In terms of the spatial layout, three indexes were included: Firstly, the service coverage rates of different levels of medical institutions, based on residents' medical orientations, were calculated using network analysis methods. Secondly, the Huff-2SFCA method was improved to calculate the accessibility of medical resources for four different modes of transportation. Then, the Health Resource Agglomeration Degree (HRAD) and Population Agglomeration Degree (PAD) were used to quantify the equity of medical resources. In terms of the supply and demand of medical resources, one index was included: the supply-demand ratio of medical resources during sudden public health events, which was calculated using the number of beds per thousand people as an indicator. These four indexes were weighted using the entropy weight method to obtain the rationality grade of medical resource spatial allocation in Taiyuan City. The study found that the rationality evaluation level of medical resource allocation in the central urban area of Taiyuan City followed a "concentrically decreasing" pattern. The rating ranged from "very reasonable" to "less reasonable", with the area of each level expanding gradually. The areas rated within the top two categories only accounted for 19.92% of the study area, while the area rated as "less reasonable" occupied 38.73% of the total area. These results indicate that the model accounted for residents' travel for various medical orientations and the availability of resources during public health emergencies. It considered both the spatial layout and supply and demand of medical resources, offering recommendations for the precise allocation of urban medical resources.

6.
Sci Rep ; 14(1): 19557, 2024 Aug 22.
Artículo en Inglés | MEDLINE | ID: mdl-39174626

RESUMEN

The lockbolt structure is essential in railway wagons, and a scientific lockbolt layout can ensure uniform load distribution, thereby preventing failure. However, current engineering lacks layout optimization methods that address multidimensional failure modes. This paper presents a new lockbolt structure layout optimization method based on submodel, parametric models, and a multi-strategy integrated NSGA-III (MSNSGA-III), adhering to the DVS EFB 3435-2 standard. This method simultaneously optimizes the number and spacing of lockbolts to prevent tensile, bearing, shear, and other static failure modes under specified load conditions. The proposed method was applied during the design phase of a container flatcar. Optimization results indicate that, compared to NSGA-III, this method achieves the best IGD and HV values across multiple complex test functions, demonstrating superior performance in solving complex Pareto front optimization problems. Additionally, the optimized lockbolt structure's safety margins increased by a maximum of 59.81%, passing the full vehicle strength test and significantly enhancing resistance to multidimensional failure modes. These results highlight the method's significant practical application value in addressing the optimization of railway wagon lockbolt structures under complex multidimensional failure modes.

7.
J Sci Food Agric ; 2024 Jul 10.
Artículo en Inglés | MEDLINE | ID: mdl-38984444

RESUMEN

BACKGROUND: Reserved arable lands in China is of great significance for rationally allocating crop planting structures, alleviating the pressure of grain imports, and protecting food security. Owing to data acquisition limitations, obtaining the spatial distribution of reserved arable lands at large spatial scales is relatively rare, and there is little information on predicting the suitability, production capacity, and ecological effects of crop cultivation in reserved arable lands. This study obtained the distribution of reserved arable lands in China by applying restrictive factors, and used the Food and Agriculture Organisation of the United Nations (FAO) suitability index for eight crops to obtain a spatial distribution map of suitable crops, proposed a cropland ecological efficiency index (CEEI) to analyse the ecological impact of crop cultivation in reserved arable lands. RESULTS: China possesses approximately 3.93 million hectares of viable reserved arable lands comprising primarily grasslands (67.68%), sandy land (8.11%), saline-alkali land (20.68%), and bare land (3.53%). The average CEEI for the eight crops under irrigation conditions ranges from 0.844 to 0.865, and that under rain-fed conditions (excluding rice) ranges from 0.609 to 0.779. CONCLUSION: We proposed the development of rain-fed agriculture with sorghum as the primary crop in the central part of Shanxi and Inner Mongolia, while promoting the cultivation of rapeseed and soybeans in the eastern parts of Heilongjiang, Jilin, and Inner Mongolia. Overall, the development of irrigation agriculture focusing on wheat and barley should be pursued only when water resources are guaranteed, particularly in north-western regions such as Gansu, Ningxia, Xinjiang, Qinghai, and Shaanxi. © 2024 Society of Chemical Industry.

8.
Micromachines (Basel) ; 15(7)2024 Jul 05.
Artículo en Inglés | MEDLINE | ID: mdl-39064396

RESUMEN

The problem that the conventional double-exponential transient current model (DE model) can overdrive the circuit, which leads to the overestimation of the soft error rate of the logic cell, is solved. Our work uses a new and accurate model for predicting the soft error rate that brings the soft error rate closer to the actual. The piecewise double-exponential transient current model (PDE model) is chosen, and the accuracy of the model is reflected using the Layout Awareness Single Event Multi Transients Soft Error Rate Calculation tool (LA-SEMT-SER tool). The model can characterize transient current pulses piecewise and limit the peak current magnitude to not exceed the conduction current. TCAD models are constructed from 28 nm process library and cell layouts. The transfer characteristic curves of devices are calibrated, and functional timing verification is performed to ensure the accuracy of the TCAD model. The experimental results show that the PDE model is not only more consistent with TCAD simulation than the DE model in modeling the single event transient currents of the device, but also that the SER calculated by the LA-SEMT-SER tool based on the PDE model has a smaller error than the SER calculated by the LA-SEMT-SER tool based on the DE model.

9.
J Integr Bioinform ; 2024 Jul 12.
Artículo en Inglés | MEDLINE | ID: mdl-38996084

RESUMEN

We present a method for the layout of anatomical structures and blood vessels based on information from the Foundational Model of Anatomy (FMA). Our approach integrates a novel vascular layout into the hierarchical treemap representation of anatomy as used in ApiNATOMY. Our method aims to improve the comprehension of complex anatomical and vascular data by providing readable visual representations. The effectiveness of our method is demonstrated through a prototype developed in VANTED, showing potential for application in research, education, and clinical settings.

10.
Sci Rep ; 14(1): 16676, 2024 Jul 19.
Artículo en Inglés | MEDLINE | ID: mdl-39030242

RESUMEN

To address the issue of roadway support failure in narrow coal pillars under dual-lane layout, this study takes the 4309 working face of Changping Coal Mine as the engineering background and employs theoretical calculations, numerical simulations, and on-site monitoring to investigate the instability mechanisms of narrow coal pillars under dual-lane conditions and to optimize technical solutions. The results indicate that the internal stress distribution within the coal pillar is influenced by the advanced support stress, and as the working face advances, the gradually increasing advanced support pressure causes the vertical stress peak within the coal pillar to shift away from the goaf area. Computational analysis reveals that the vertical stress in the top region of a 6 m narrow coal pillar is 38% higher than that in the bottom region, with an average stress of 16 MPa in the coal pillar. The asymmetric high-level stress concentration within the coal pillar significantly affects its stability. A UDEC (Universal Distinct Element Code) model was established to compare four simulation schemes with cut-off angles of 0°, 5°, 10°, and 15°. Based on the analysis of damage parameters and fracture distribution in the narrow coal pillar roadway, it was concluded that the stability is best when the cut-off angle is 10°. The dense drilling cut-off unloading technology was applied to the 4309 working face of the Changping Mine based on the aforementioned research. On-site monitoring results show that the relative deformation of the roof and bottom plates and the two sides of the test section were controlled within 267 mm and 198 mm, respectively, effectively resolving the deformation and instability issues of the narrow coal pillars.

11.
Sci Total Environ ; 948: 174851, 2024 Oct 20.
Artículo en Inglés | MEDLINE | ID: mdl-39029751

RESUMEN

Green infrastructure (GI) plays a significant role in alleviating urban flooding risk caused by urbanization and climate change. Due to space and financial limitations, the successful implementation of GI relies heavily on its layout design, and there is an increasing trend in using multi-objective optimization to support decision-making in GI planning. However, little is known about the hydrological effects of synchronously optimizing the size, location, and connection of GI under climate change. This study proposed a framework to optimize the size, location, and connection of typical GI facilities under climate change by combining the modified non-dominated sorting genetic algorithm-II (NSGA-II) and storm water management model (SWMM). The results showed that optimizing the size, location, and connection of GI facilities significantly increases the maximum reduction rate of runoff and peak flow by 13.4 %-24.5 % and 3.3 %-18 %, respectively, compared to optimizing only the size and location of GI. In the optimized results, most of the runoff from building roofs flew toward green space. Permeable pavement accounted for the highest average proportion of GI implementation area in optimal layouts, accounting for 29.8 %-54.2 % of road area. The average cost-effectiveness (C/E) values decreased from 16 %/105 Yuan under the historical period scenario to 14.3 %/105 Yuan and 14 %/105 Yuan under the two shared socioeconomic pathways (SSPs), SSP2-4.5 and SSP5-8.5, respectively. These results can help in understanding the optimization layout and cost-effectiveness of GI under climate change, and the proposed framework can enhance the adaptability of cities to climate change by providing specific cost-effective GI layout design.

12.
J Environ Manage ; 366: 121767, 2024 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-38986369

RESUMEN

Optimizing the layout of urban stormwater management systems is an effective method for mitigating the risk of urban flooding under extreme storms. However, traditional approaches that consider only economic costs or annual runoff control rates cannot dynamically respond to the uncertainties of extreme weather, making it difficult to completely avoid large accumulations of water and flooding in a short period. This study proposes an integrated method combining system layout optimization and Model Predictive Control(MPC)to enhance the system's resilience and effectiveness in flood control. An optimization framework was initially built to identify optimal system layouts, balancing annual average life cycle cost (AALCC) and resilience index. The MPC was then applied to the optimal layout selected using the Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) method, aiming to alleviate inundation cost-effectively. The adaptability of MPC to varying sets of control horizons and its efficacy in managing the hydrograph and flood dynamics of urban drainage system were examined. Conducted in Yubei, Chongqing, this study revealed patterns in optimal layout fronts among various extreme design rainfalls, showing that peak position rate and return period significantly influence system resilience. The contribution of MPC to the optimal system layout was particularly notable, resulting in improved instantaneous and overall flood mitigation. The application of MPC increased the resilience index by an average of 0.0485 and offered cost savings of 0.0514 million yuan in AALCC. Besides, our findings highlighted the importance of selecting an optimal set of control horizons for MPC, which could reduce maximum flood depth from 0.43m to 0.19m and decrease conduit peak flow by up to 14% at a flood-prone downstream location.


Asunto(s)
Inundaciones , Modelos Teóricos , Lluvia , Movimientos del Agua
13.
Heliyon ; 10(11): e32401, 2024 Jun 15.
Artículo en Inglés | MEDLINE | ID: mdl-38961924

RESUMEN

Urban guide signs, a fundamental component of traffic sign systems, convey both directional and locational information. Previous studies mainly focused on the font or volume of information, while little attention was paid to the layout of text-based Chinese guide signs, which is an unregulated area but crucial in practical applications and related to people's travel safety. This study investigates the impact of text layout and information volume on the spatial representation of road networks through two experimental studies, examining the effects of different designs on path determination and global road network knowledge. The results indicate that the text layout of urban road guide signs significantly influences the formation of spatial representation of the road network. Specifically, vertical guide signs displaying road names on both sides proved more effective than horizontal ones. While the volume of road name information does not markedly affect the formation of spatial representation, the arrangement of road names does influence the determination of information volume, with vertical layouts facilitating the presentation of more information. It is anticipated that these design recommendations for road signs can effectively mitigate the incidence of road traffic accidents.

14.
ACS Sens ; 9(7): 3671-3679, 2024 Jul 26.
Artículo en Inglés | MEDLINE | ID: mdl-38937945

RESUMEN

Flexible sensors have developed rapidly due to their great application potential in the intelligent era. However, the frequent bending work requirements pose a serious challenge to the mechanical reliability of flexible sensors. Herein, a strategy of using a new multielectrode layout to achieve multiple sensing signals based on one external signal is proposed for the first time to improve the reliability of flexible piezoresistive sensors. The multielectrode layout consists of a pair of interdigital electrodes and a bottom electrode. The interdigitated electrodes are used to sense the change in the surface resistance of the sensor, and the interdigital electrodes and the bottom electrode are used to sense the change in the bulk resistance of the sensor. As a result, without increasing the sensing unit area, the electrode layout allows the sensor to generate three response electrical signals when sensing an external pressure, thus improving the reliability of the sensor. Based on the electrode layout, a highly reliable flexible piezoresistive sensor with a multilevel porous structure is obtained by a microwave foaming method with a template. In the working state of sensing surface resistance, the sensor has a 22.12 kPa-1 sensitivity. Meanwhile, in the working state of sensing bulk resistance, the sensor shows a 55.17 kPa-1 sensitivity. Furthermore, the sensor is applied to monitor human pulse and speech signals, demonstrating its multisignal output characteristics and potential applications in flexible electronics. In conclusion, the new strategy of using the proposed electrode layout to improve the reliability of flexible sensors is expected to greatly promote the practical application of flexible electronics.


Asunto(s)
Electrodos , Humanos , Dispositivos Electrónicos Vestibles , Pulso Arterial , Diseño de Equipo
15.
Sci Rep ; 14(1): 13947, 2024 06 17.
Artículo en Inglés | MEDLINE | ID: mdl-38886544

RESUMEN

The arrangement of Chinese characters has a significant impact on the visual effect and information dissemination in graphic design. In traditional Chinese layout, vertical arrangement of characters is predominant, but in recent times, there has been a gradual transition towards horizontal arrangement. To compare the influence of different character arrangement forms on visual meaning generation and information dissemination, This study employed an eye-tracking experiment to investigate two common Chinese character layouts in posters-horizontal and vertical, and collected data such as eye-tracking heatmap, pupil diameter and eye-tracking trajectory map. Based on objective eye-tracking data, combined with post-test interviews and questionnaire surveys, it was found that vertical character arrangement in Chinese typography is more effective in attracting visual attention and facilitating the expression and stimulating interest in viewing/reading under the premise of meeting formal requirements, which may provide guidance and inspiration for the practical application of Chinese characters in layout design, advertising design, packaging design, exhibition design, UI design, and other related fields.


Asunto(s)
Tecnología de Seguimiento Ocular , Difusión de la Información , Humanos , Femenino , Masculino , Difusión de la Información/métodos , Adulto , Adulto Joven , China , Lectura , Atención/fisiología , Movimientos Oculares/fisiología , Encuestas y Cuestionarios
16.
Sensors (Basel) ; 24(11)2024 Jun 04.
Artículo en Inglés | MEDLINE | ID: mdl-38894432

RESUMEN

The rocket sled, as a ground dynamic test system, combines the characteristics of the wind tunnel test and the flight test. However, some practical factors, such as shock wave interference, ground effect, and high-intensity aerodynamic noise will cause serious interference and even failure of the uniformly distributed sensors during horizontal sliding in a wide speed range. The AGARD HB-2 standard model is employed as the payload to simulate the aerodynamic and aeroacoustic characteristics during the variable acceleration period, aiming to optimize the test sensors layout. It is observed that in the high Mach number flow fields, strong coupling behaviors among complex waves will occur. The peak of wake vortex strength will appear at 1.5 s and gradually diminish over time. In addition, when the vortex between the load and the booster is monitored, its position shifts forward in the subsonic stage, then gradually moves backward and expands in the supersonic stage. Acoustic directivity is pronounced at subsonic and transonic speeds, pointing towards 75° and 135° relative to the sliding speed, respectively. These results can provide technical support for sensor layout and high-precision testing in rocket sled tests.

17.
HERD ; : 19375867241248593, 2024 May 06.
Artículo en Inglés | MEDLINE | ID: mdl-38711302

RESUMEN

OBJECTIVES: This research aims to propose a novel methodology for analyzing and optimizing wayfinding in complex environments by examining their spatial configurations. BACKGROUND: Wayfinding difficulties often lead to disorientation and hinder users' ability to locate destinations. Although architectural design can aid in simplifying user access, existing approaches lack a specific focus on wayfinding optimization despite its significant impact on users' navigational abilities. METHODS: In this study, an agent-based model was employed to assess the efficacy of wayfinding in a multistory hospital. Subsequently, the layouts were optimized, leading to the creation of a new space distribution diagram. The simulation was then repeated to examine the potential improvement in wayfinding. Data collection encompassed user types, workflow scenarios, population distribution, and user speed. RESULTS: Comparative analysis of the agent-based simulation findings before and after layout optimization revealed a decrease in total distance and time spent on the modified floor plans for all users when compared to the existing layout. This suggests that the optimized layout holds significant potential for enhancing wayfinding performance. Given the positive outcomes observed for users, this approach is particularly well suited for preliminary design stages of complex environments, where designations among user groups are less crucial or flexibility is desired. Additional advantages include the ability to generate a comprehensive simulation of users' daily workflow, which is integrated into the optimization process and considers specific requirements regarding spatial adjacency.

18.
Sci Rep ; 14(1): 11258, 2024 05 17.
Artículo en Inglés | MEDLINE | ID: mdl-38755199

RESUMEN

Improving access to HIV/AIDS healthcare services is of great concern to government and policymakers striving to strengthen overall public health. How to reasonably allocate HIV/AIDS healthcare resources and maximize the equality of access to healthcare services across subdistrict areas has become an urgent problem to be solved. However, there is limited research on this topic in China. It is necessary to evaluate spatial accessibility to improve the accessibility and equity of HIV/AIDS healthcare services. In this study, the improved multi-modal two-step floating catchment area (2SFCA) and inverted 2SFCA (i2SFCA) methods are used to measure the spatial accessibility of HIV/AIDS healthcare services and the crowdedness of the healthcare sites in Shandong Province, China. Then, the theoretical supply and the optimal spatial distribution of resources are calculated and visualized by minimizing the accessibility gaps between demand locations. This study showed that the spatial accessibility of HIV/AIDS service resources in Shandong Province was concentrated and unevenly distributed, and the accessibility scores in the marginal areas of prefecture-level cities were significantly lower than those in other areas. Regions with a large number of doctors had significantly higher levels of spatial accessibility. The ART accessibility scores in the southwest of Shandong Province were higher than those in other regions. As the travel friction coefficient increased, the accessibility scores formed an approximately circular cluster distribution centered on the healthcare sites in geographical distribution. More ART drugs needed to be supplied in marginal areas and more doctors were needed to work on HIV/AIDS in urban areas to address the spatial distribution imbalance of HIV/AIDS healthcare services. This study profoundly analyzed the spatial accessibility of HIV/AIDS healthcare services and provided essential references for decision-makers. In addition, it gives a significant exploration for achieving the goal of equal access to HIV/AIDS healthcare services in the future.


Asunto(s)
Síndrome de Inmunodeficiencia Adquirida , Infecciones por VIH , Accesibilidad a los Servicios de Salud , China/epidemiología , Humanos , Infecciones por VIH/epidemiología , Infecciones por VIH/terapia , Síndrome de Inmunodeficiencia Adquirida/epidemiología , Síndrome de Inmunodeficiencia Adquirida/terapia , Análisis Espacial , Áreas de Influencia de Salud
19.
Water Res ; 257: 121640, 2024 Jun 15.
Artículo en Inglés | MEDLINE | ID: mdl-38776755

RESUMEN

We present a new modular model called TURN-Sewers for exploring different adaptations of centralised wastewater infrastructure towards more decentralised wastewater systems under different urban development scenarios. The modular model is flexible and computationally efficient in exploring transitions at the city scale, allowing for the comparison of different policies and management strategies for sanitary wastewater infrastructure. TURN-Sewers includes independent modules that simulate the generation, dimensioning, deterioration, management, and calculation of performance indicators for different wastewater systems. This model can use readily available spatial information to support infrastructure planners and other stakeholders in exploring different transition pathways from centralised to decentralised wastewater infrastructure. An illustrative example demonstrates how TURN-Sewers can generate multiple future alternatives, define different infrastructure management strategies regarding system expansion, rehabilitation and transition, and assess the economic, hydraulic and structural impacts.


Asunto(s)
Modelos Teóricos , Aguas del Alcantarillado , Eliminación de Residuos Líquidos , Aguas Residuales , Eliminación de Residuos Líquidos/métodos , Ciudades
20.
Animals (Basel) ; 14(10)2024 May 16.
Artículo en Inglés | MEDLINE | ID: mdl-38791697

RESUMEN

The analysis of the genetic diversity and historical dynamics of endemic endangered goose breeds structure has attracted great interest. Although various aspects of the goose breed structure have been elucidated, there is still insufficient research on the genetic basis of endemic endangered Chinese goose breeds. In this study, we collected blood samples from Lingxiang White (LX), Yan (YE), Yangjiang (YJ), Wuzong (WZ), Xupu (XP), and Baizi (BZ) geese (Anser cygnoides) and used Sanger sequencing to determine the partial sequence of the cytochrome b (CYTB) gene in a total of 180 geese. A total of 117 polymorphic sites were detected in the 707 bp sequence of the mtDNA CYTB gene after shearing and correction, accounting for approximately 16.55% of the entire sequence. The AT content (51.03%) of the processed sequence was slightly higher than the GC content (48.97%), indicating a preference for purine bases. The YJ, YE, and WZ breeds had the highest population genetic diversity, with a haplotype diversity greater than 0.9 (Hd > 0.9) and average population nucleotide difference of 8.01 (K > 8.01). A total of 81 haplotypes were detected and divided into six major branches. Among the six goose breeds, there were frequent genetic exchanges among LX, YJ, YE, and WZ geese (Nm > 15.00). We analyzed the distribution of base-mismatch differences in goose breeds and tested their historical dynamics for neutrality in Tajima's D and Fu's Fs. For YJ and WZ geese, Tajima's D > 0, but the difference was not significant (p > 0.05). The actual values for the two breeds exhibited multimodal Poisson distributions. The population patterns of the WZ and YJ geese are purportedly relatively stable, and the breeds have not experienced population expansions or bottleneck effects, which is consistent with the neutrality test results. This study provides new insights into the diverse genetic origins and historical dynamics that sustain endemic endangered goose breeds.

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