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To address high HIV prevalence rates in Haiti, disseminating information about HIV transmission has been emphasized. Yet, after several decades, we do not know how effective HIV information dissemination has been in reducing HIV misconceptions. Using the 2005-06, 2012, and 2016-17 Haiti Demographic and Health Surveys and applying logistic regression, we found nuanced gender dynamics in endorsing HIV misconceptions over time. Among females at the bivariate level, the odds of endorsement of HIV misconceptions in 2012 (OR = 0.87, p < 0.05) and 2016-17 (OR = 0.68, p < 0.001) had declined compared to 2005-06. At the multivariate level, however, we observed that demographic factors suppressed the difference between 2005-06 and 2012, although those in 2016-17 (OR = 0.71, p < 0.001) were still less likely to endorse HIV misconceptions. However, this relationship disappeared once we added behavioral factors (OR = 0.93, p > 0.05). Among males, after controlling for demographic, socioeconomic, and behavioral factors at the multivariate level, those in 2012 (OR = 1.55, p < 0.001) and 2016-17 (OR = 1.24, p < 0.01) were more likely to endorse HIV misconceptions compared to men in 2005-06. We recommend that while improving women's access to HIV services, it is important to incorporate the HIV needs of males into the National HIV policy priority areas.
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Infecciones por VIH , Masculino , Humanos , Femenino , Haití/epidemiología , Infecciones por VIH/epidemiología , Infecciones por VIH/prevención & control , Conocimientos, Actitudes y Práctica en SaludRESUMEN
ABSTRACT Background: Low bone mass density (BMD) is an extraintestinal finding in celiac disease (CD). This may result in bone fractures leading to loss in quality of life. Objective: To assess BMD in male CD patients at diagnosis according to the patient's age. Methods: Descriptive retrospective carried out during the period between 2013 and 2023 in a single office that studied dual-energy X-ray absorptiometry (DXA) results in 28 male patients with a recent diagnosis of CD, divided into three groups: group 1 (age up to 18 years); group 2 (from 19 to 49 years of age) and group 3 (over 50 years of age). Were studied demographic and anthropometric parameters, time delay between symptoms onset and CD diagnosis and fracture occurrence. Results: Celiac patients studied had median age 36.0 years (IQR=16.5-50.7). Among them, 39.3% had osteopenia and 14.3% had osteoporosis. Only 36% of the sample had normal DXA values (group 1 with 37.5%; group 2 with 46% and group 3 with 14.2%). No pathological fracture was observed in this sample. CD diagnosis delay observed had median 1.0 year (IQR=1.0-4.7). When the number of individuals with normal and abnormal DXA results were compared, there was no difference in body mass index, time of diagnosis delay or Marsh classification (P=0.18). Conclusion: Male patients at the time of CD diagnosis showed a high prevalence of low BMD, which was particularly evident in individuals over 50 years of age.
RESUMO Contexto: A baixa densidade de massa óssea (DMO) é um achado extraintestinal na doença celíaca (DC). Isso pode resultar em fraturas ósseas levando à perda de qualidade de vida. Objetivo: Avaliar a DMO em pacientes masculinos com DC no momento do diagnóstico de acordo com a idade do paciente. Métodos: Estudo retrospectivo descritivo realizado no período entre 2013 e 2023 em um único consultório que estudou resultados de "dual-energy X-ray absorptiometry" (DEXA) em 28 pacientes do sexo masculino com diagnóstico recente de DC, divididos em três grupos: grupo 1 (idade até 18 anos); grupo 2 (de 19 a 49 anos) e grupo 3 (acima de 50 anos). Foram estudados parâmetros demográficos e antropométricos, tempo decorrido entre o início dos sintomas e o diagnóstico da DC e ocorrência de fraturas. Resultados: Os pacientes celíacos estudados tinham mediana de idade de 36,0 anos (IIQ=16,5-50,7). Dentre eles, 39,3% apresentavam osteopenia e 14,3% apresentavam osteoporose. Apenas 36% da amostra apresentou valores normais de DEXA (grupo 1 com 37,5%; grupo 2 com 46% e grupo 3 com 14,2%). Nenhuma fratura patológica foi observada nesta amostra. O atraso no diagnóstico da DC observado teve mediana de 1,0 ano (IQR=1,0-4,7). Quando comparado o número de indivíduos com resultados de DEXA normais e alterados, não houve diferença no índice de massa corporal, tempo de atraso no diagnóstico ou classificação de Marsh (P=0,18). Conclusão: Pacientes do sexo masculino no momento do diagnóstico da DC apresentaram alta prevalência de baixa DMO, o que foi particularmente evidente em indivíduos com mais de 50 anos de idade.
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INTRODUCTION: Diagnosing and treating human immunodeficiency virus carriers has led to the identification of a higher prevalence of said infection and, therefore, of a higher risk of transmission of the virus. OBJECTIVE: To find out the trend of new cases of human immunodeficiency virus infection carriers at the Instituto Mexicano del Seguro Social (IMSS) in Mexico within the 2003-2017 period. METHODS: Patients affiliated to the IMSS were analyzed. Data from 42,181 newly-diagnosed cases were collected, with variations related to gender and age being observed. Age-standardized rates per 100,000 population were obtained. RESULTS: The highest mean annual percentage change in males was documented in adolescents (13.0, 95% CI = 9.9, 16.1). Heterogeneous trends were recorded for women, with a significant overall decrease (-2.2, 95% CI = -3.4, -1.0), but growing trends were also observed in some groups. CONCLUSIONS: Our results suggest that the human immunodeficiency epidemic in patients cared for at the Instituto Mexicano del Seguro Social is concentrated in males, with a growing trend particularly in adolescents.
INTRODUCCIÓN: Hacer el diagnóstico y tratar a portadores del virus de la inmunodeficiencia humana ha llevado a identificar mayor prevalencia de esa infección y, por lo tanto, de un mayor riesgo de transmisión de este virus. OBJETIVO: Conocer la tendencia en México de los nuevos casos de portadores de infección por el virus de la inmunodeficiencia humana en el Instituto Mexicano del Seguro Social (IMSS) en el periodo 2003-2017. MÉTODOS: Se analizaron pacientes asegurados en el IMSS. Se obtuvieron datos de 42 181 casos recién diagnosticados y se analizaron las variaciones relacionadas con el sexo y la edad. Se obtuvieron las tasas estandarizadas por edad por 100 000 personas. RESULTADOS: El cambio porcentual anual promedio más alto en hombres se documentó en adolescentes varones (13.0, IC 95 % = 9.9, 16.1). Se registraron tendencias heterogéneas en las mujeres, con una disminución total significativa (2.2, IC 95 % = 3.4, 1.0), pero también se observaron tendencias crecientes en algunos grupos. CONCLUSIONES: Los resultados sugieren que en el IMSS, la epidemia de la inmunodeficiencia humana adquirida se concentra en hombres, con tendencia creciente particularmente en adolescentes.
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Infecciones por VIH , Seguridad Social , Masculino , Adolescente , Humanos , Femenino , México/epidemiología , Infecciones por VIH/epidemiología , Academias e Institutos , PrevalenciaRESUMEN
Vector-borne pathogens (VBPs) are primarily transmitted by arthropod vectors, but secondary ways of transmission have been described, including via venereal route. Nonetheless, there is still limited research on possible sexual transmission of VBPs in dogs. We molecularly investigated the presence of vector-borne pathogens in semen from dogs living in an area where these agents are endemic. Upon PCR testing, seven out of 22 (31.8%) semen samples tested positive for at least one VBP, whereas simultaneous positivity to two or more pathogens was detected in three (13.6%) dogs. Among pathogens detected in semen, Trypanosoma cruzi (n = 1) and Leishmania infantum (n = 3) were identified to species level by restriction fragment length polymorphism analysis. Attempts to sequence PCR products from other pathogens were unsuccessful, but coupled epidemiological and molecular data suggest the presence of Anaplasma platys (n = 5), Babesia vogeli (n = 1) and Ehrlichia canis (n = 1) in semen from dogs. Further experimental studies would be needed to confirm the sexual transmission hypothesis for these VBPs and also the possible implications of these findings for canine reproduction.
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Vectores de Enfermedades , Semen , Perros , Animales , Brasil/epidemiología , Vectores Artrópodos , Ehrlichia canis/genéticaRESUMEN
Resumen Introducción: Hacer el diagnóstico y tratar a portadores del virus de la inmunodeficiencia humana ha llevado a identificar mayor prevalencia de esa infección y, por lo tanto, de un mayor riesgo de transmisión de este virus. Objetivo: Conocer la tendencia en México de los nuevos casos de portadores de infección por el virus de la inmunodeficiencia humana en el Instituto Mexicano del Seguro Social (IMSS) en el periodo 2003-2017. Métodos: Se analizaron pacientes asegurados en el IMSS. Se obtuvieron datos de 42 181 casos recién diagnosticados y se analizaron las variaciones relacionadas con el sexo y la edad. Se obtuvieron las tasas estandarizadas por edad por 100 000 personas. Resultados: El cambio porcentual anual promedio más alto en hombres se documentó en adolescentes varones (13.0, IC 95 % = 9.9, 16.1). Se registraron tendencias heterogéneas en las mujeres, con una disminución total significativa (-2.2, IC 95 % = -3.4, -1.0), pero también se observaron tendencias crecientes en algunos grupos. Conclusiones: Los resultados sugieren que en el IMSS, la epidemia de la inmunodeficiencia humana adquirida se concentra en hombres, con tendencia creciente particularmente en adolescentes.
Abstract Introduction: Diagnosing and treating human immunodeficiency virus carriers has led to the identification of a higher prevalence of said infection and, therefore, of a higher risk of transmission of the virus. Objective: To find out the trend of new cases of human immunodeficiency virus infection carriers at the Instituto Mexicano del Seguro Social (IMSS) in Mexico within the 2003-2017 period. Methods: Patients affiliated to the IMSS were analyzed. Data from 42,181 newly-diagnosed cases were collected, with variations related to gender and age being observed. Age-standardized rates per 100,000 population were obtained. Results: The highest mean annual percentage change in males was documented in adolescents (13.0, 95% CI = 9.9, 16.1). Heterogeneous trends were recorded for women, with a significant overall decrease (-2.2, 95% CI = -3.4,-1.0), but growing trends were also observed in some groups. Conclusions: Our results suggest that the human immunodeficiency epidemic in patients cared for at the Instituto Mexicano del Seguro Social is concentrated in males, with a growing trend particularly in adolescents.
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Zika virus (ZIKV) is a positive-sense single-stranded RNA flavivirus and is mainly transmitted by Aedes mosquitoes. This arbovirus has had a significant impact on health in recent years by causing malformations, such as microcephaly in babies and Guillain-Barré syndrome in adults. Some evidence indicates that ZIKV can be sexually transmitted and may persist in the male reproductive tract for an extended period in humans. Knockout and vasectomized mice have been used as models to reveal ZIKV infection in the male reproductive tract as a virus source. ZIKV presence in male and female mosquito reproductive tracts and eggs point to venereal and vertical/transovarian transmission, again demonstrating that the reproductive tract can be involved in the spread of ZIKV. Moreover, eggs protected by eggshells have the potential to be a ZIKV reservoir. Given the +-lack of vaccines and therapies for Zika fever and the underestimated prevalence rate, an understanding of ZIKV infection and its spread from the reproductive tract, which is protected from the immune system and potentially active for virus transmission, is imperative. We must also develop cheaper, more efficient techniques for virological surveillance inside vectors and humans, control vectors with ecofriendly insecticides, and promote condom use to avoid ZIKV contamination during sexual intercourse, as recommended by the World Health Organization.
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Aedes , Insecticidas , Infección por el Virus Zika , Virus Zika , Animales , Femenino , Humanos , Masculino , Ratones , Ratones Noqueados , Mosquitos Vectores , ARN , Virus Zika/genéticaRESUMEN
Phytoestrogens are considered to be endocrine disruptors, since they can alter the endocrine system, thus disturbing many reproductive events. The intake of diets containing a high content of phytoestrogens has increased worldwide in human populations and in domestic animals. Phytoestrogens in maternal blood can pass through the placenta to the fetus in high amounts and can have long-term organizational effects. Mesquite (Prosopis sp) is a leguminous plant widely used to feed several livestock species, and is also used in the human diet. In this study we assessed the effects of exposure to mesquite pod extract during the periconception and pregnancy periods on the reproduction of male and female descendants. The females of three experimental groups received one of the following treatments: 1) vehicle injection; 2) mesquite pod extract or 3) the isoflavone daidzein during the periconception and pregnancy periods. Estrous cyclicity, sexual behavior and hormones, as well as uterine and vaginal epithelia were evaluated in the female descendants. In the males, sexual behavior and hormones, apoptosis in testicular cells and sperm quality were evaluated. In females the following was observed: alterations in estrous cycles, decreased sexual behavior, estradiol and progesterone levels, increased uterine and vaginal epithelia. In males, we observed a decrease in sexual behavior, testosterone and sperm quality, and apoptosis increased in testicular cells. All these effects were similar to those caused by daidzein. These results indicate that prenatal exposure to mesquite pod extract or daidzein, administered to females before and during pregnancy, can disrupt normal organizational-activational programming of reproductive physiology in female and male descendants.
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Isoflavonas , Prosopis , Animales , Estradiol , Femenino , Humanos , Masculino , Fitoestrógenos , Extractos Vegetales , Embarazo , Ratas , Reproducción , SemillasRESUMEN
OBJECTIVE: Human sperm parameters varies widely among men and even between consecutive samples in the same individual with respect to their concentration, motility, morphology, and DNA fragmentation. Less is known about the characteristics of sperm in short abstinence periods. Hence, the current study was conducted to determine the influence of consecutive ejaculate on above parameters after short abstinence period in oligospermic males. METHODS: This observational study was conducted from January 2018 to February 2019 and included 67 men undergoing primary infertility treatment at the SDM Fertility Centre, Dharwad, India. The first semen sample was provided after an abstinence period of 2-7 days, while the second sample was collected 1-3 h after the first. The two consecutive semen samples were analyzed according to the 2010 WHO criteria for semen analysis and their parameters were compared. Sperm DNA fragmentation was also measured. RESULTS: Most of the participants were aged of 31 to 40 years (68.6%). The majority of them had the second sample collected after a 1-hour interval (88%); 10.4% of the subjects had the second sample collected after a 2-hour interval; the remaining 1.4% had the second sample collected after a 3-hour interval. Mean concentration (mill/ml), total motility, and progressive motility (%) were significantly higher in the second sample (p<0.05). The second sample also showed lower DNA fragmentation than the first ejaculate sample. CONCLUSIONS: Our study inferred that consecutive semen samples collected 1-3 hours apart might have a role in managing subfertility in oligospermic males. Further research, possibly a randomized clinical trial, is needed to explore this association.
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Eyaculación , Motilidad Espermática , Anciano , Humanos , Masculino , Análisis de Semen , Recuento de Espermatozoides , EspermatozoidesRESUMEN
Waste oil from olive oil extraction industry was used, instead of soybean oil, in heavy roosters diet in order to evaluate birds reproductive parameters. Atotal of forty roosters were housed individually in boxes with 1.2 m². Two experimental diets were used: control diet, based on corn, soybean meal, and soybean oil; and test diet, where soybean oil was totally replaced by waste oil. In order to verify weight gain and feed intake, animals were individually weighed weekly. Seven semen collections were performed with fifteen-day interval. Reproductive variables analyzed sperm volume, motility, concentration, and morphology. No statistical difference (p >0.05) was observed between treatments at the different collection periods for the variables sperm volume, motility, and concentration. There was a statistically significant difference between treatments for body weight in periods three (p =0.04), and seven (p=0.04). Statistical differences (p =0.01) were also observed between treatments for abnormal sperm morphology. Among collection periods, statistical difference was observed for motility (p =0.00), and sperm concentration (p =0.01). Total replacement of soybean oil by waste oil from olive oil extraction in young heavy roosters diets does not affect sperm volume, motility, and concentration; reduces defects in sperm tail, and promotes better weight gain control.(AU)
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Animales , Masculino , Pollos/anatomía & histología , Pollos/fisiología , Aumento de Peso , Alimentación Animal/análisis , OleaRESUMEN
Waste oil from olive oil extraction industry was used, instead of soybean oil, in heavy roosters' diet in order to evaluate birds' reproductive parameters. A total of forty roosters were housed individually in boxes with 1.2 m². Two experimental diets were used: control diet, based on corn, soybean meal, and soybean oil; and test diet, where soybean oil was totally replaced by waste oil. In order to verify weight gain and feed intake, animals were individually weighed weekly. Seven semen collections were performed with fifteen-day interval. Reproductive variables analyzed sperm volume, motility, concentration, and morphology. No statistical difference (p > 0.05) was observed between treatments at the different collection periods for the variables sperm volume, motility, and concentration. There was a statistically significant difference between treatments for body weight in periods three (p = 0.04), and seven (p = 0.04). Statistical differences (p = 0.01) were also observed between treatments for abnormal sperm morphology. Among collection periods, statistical difference was observed for motility (p = 0.00), and sperm concentration (p = 0.01). Total replacement of soybean oil by waste oil from olive oil extraction in young heavy roosters' diets does not affect sperm volume, motility, and concentration; reduces defects in sperm tail, and promotes better weight gain control.(AU)
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Animales , Masculino , Aumento de Peso/fisiología , Pollos/fisiología , Fenómenos Fisiológicos Reproductivos , Aceite de Oliva/efectos adversos , Alimentación Animal/análisisRESUMEN
RESUMEN Introducción: Estudios recientes han demostrado diferencias entre el sexo femenino y el masculino y su influencia en aspectos básicos de la biología, los cuales podrían influir a su vez, en la etiología y fisiopatología de enfermedades en la etapa neonatal. Es conocido que los cambios en la regulación epigenética por factores que afectan la exposición del cortisol fetal muestra efectos específicos según el tipo de sexo. Objetivo: Determinar la posible relación entre los cambios epigenéticos, el sexo masculino y las enfermedades neonatales. Métodos: Se realizó una búsqueda bibliográfica en Pubmed, Scielo, LILACS y en la plataforma Clínica Key entre los años 2017-2020, en idioma inglés y español. Se utilizaron diferentes palabras clave como diferencias sexuales, sexo masculino, epigenética y enfermedades neonatales. Análisis e integración de la información: En esta revisión se abordan aspectos como la epigenética en el desarrollo humano y su relación con el sexo, el papel de la placenta y su relación con el sexo fetal, las complicaciones perinatales y su relación con el sexo masculino. Además, se abordan las afecciones respiratorias, las afecciones neurológicas y otras de la etapa neonatal vinculadas con el sexo y la posible relación con los mecanismos epigenéticos. Conclusiones: El sexo masculino es un factor predisponente en la prevalencia de determinadas enfermedades neonatales. La epigenética puede estar involucrada en la aparición de muchas enfermedades neonatales moduladas por el sexo por mecanismos aun no bien esclarecidos. Investigaciones futuras pudieran arrojar mayor conocimiento sobre la etiopatogenia de estas enfermedades y su forma de abordarlas.
ABSTRACT Introduction: Recent studies have confirmed differences among the female and male sex and their influence in basic aspects of biology, which can also impact in the etiology and physiopathology of diseases in the neonatal stage. It is known that changes in the epigenetic regulation due to factors that affect the exposition to fetal cortisol show specific effects according to the type of sex. Objective: Determine the possible relation among the epigenetic changes, male sex and the neonatal diseases. Methods: It was carried out a bibliographic search in Pubmed, Scielo, LILACS and in the platform called Clínica Key, in the period 2017-2020, in English and Spanish languages. The following key words were used: sexual differences, male sex, epignetic and neonatal diseases. Analysis and Integration of the information: This review deals with aspects as epigenetic in human development and its relation with sex, the role of placenta and its relation with fetal sex, perinatal complications and their relation with male sex. In addition, the review also mentions respiratory conditions, neurologic conditions and others of the neonatal stage related with sex and the possible relation with epigenetic mechanisms. Conclusions: Male sex is a predisposing factor in the prevalence of certain neonatal diseases. Epigenetic can be involved in the onset of many neonatal diseases modulated by the sex due to mechanisms that are not clear yet. Future researches might show more knowledge on the etiopathogenesis of these disease and the way to approach them.
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Estrogens, particularly 17ß-estradiol (estradiol, E2), regulate memory formation. E2 acts through its intracellular receptors, estrogen receptors (ER) ERα and ERß, as well as a recently identified G protein-coupled estrogen receptor (GPER). Although the effects of E2 on memory have been investigated, studies examining the effects of GPER stimulation are scarce. Selective GPER agonism improves memory in ovariectomized female rats, but little information is available regarding the effects of GPER stimulation in male rodents. The aim of the present study was to investigate the effects of the GPER agonist, G1, on consolidation and reconsolidation of inhibitory avoidance (IA) and object recognition (OR) memory in male rats. Animals received vehicle, G1 (15, 75, 150 µg/kg; i.p.), or the GPER antagonist G15 (100 µg/kg; i.p.) immediately after training, or G1 (150 µg/kg; i.p.) 3 or 6 h after training. To investigate reconsolidation, G1 was administered immediately after IA retention Test 1. Results indicated that G1 administered immediately after training at the highest dose enhanced both OR and IA memory consolidation, while GPER blockade immediately after training impaired OR. No effects of GPER stimulation were observed when G1 was given 3 or 6 h after training or after Test 1. The present findings provide evidence that GPER is involved in the early stages of memory consolidation in both neutral and emotional memory tasks in male adult rats.
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Memoria/fisiología , Receptores Acoplados a Proteínas G/fisiología , Reconocimiento en Psicología/fisiología , Animales , Reacción de Prevención/efectos de los fármacos , Reacción de Prevención/fisiología , Antagonistas del Receptor de Estrógeno/farmacología , Estrógenos/farmacología , Masculino , Memoria/efectos de los fármacos , Motivación/fisiología , Ratas , Ratas Wistar , Receptores Acoplados a Proteínas G/efectos de los fármacos , Reconocimiento en Psicología/efectos de los fármacosRESUMEN
Este artigo aborda os sentidos produzidos por homens acerca das relações de gênero e da violência contra as mulheres. Tais considerações foram possibilitadas por uma pesquisa realizada no município de Maceió, sobre violência contra as mulheres e Atenção Básica em Saúde. Foram entrevistados três homens usuários de uma Unidade Básica de Saúde (UBS), convidados a partir de observações no cotidiano. As entrevistas foram transcritas, divididas em categorias e analisadas a partir do referencial teórico da perspectiva feminista de gênero em interface com as Práticas Discursivas e Produção de Sentidos. Aqui, são trazidas duas categorias que discutem como os homens reconhecem (ou não) as relações desiguais de poder que estruturam a sociedade e o reflexo nas práticas de violência contra as mulheres. A partir disto, percebemos a necessidade da inclusão de homens nas discussões sobre violência contra mulheres, sob um olhar crítico, situado e analítico sobre a categoria gênero.(AU)
This article debates meanings produced by men about gender relations and violence against women. Such reflections were generated from one research about violence against women and primary health care performed at Maceió city. In the research, three men, invited after daily observations, were interviewed at a primary health care centre at Maceió city. The interviews were transcribed, divided in categories and analyzed from the theoretical framework of the feminist perspective of gender in interface with the Discursive Practices and Production of Senses. From the interviews' speech, we discuss about how men recognize (or not) the unequal relations of power that structure society and how this recognition is reflected in discourses about practices of violence against women. From this, we perceive the need to include men in the discussions about violence against women, based on a critical and analitical look at the gender category.(AU)
Este artículo aborda los significados que producen los hombres sobre las relaciones de género y la violencia contra la mujer. Tales consideraciones fueron posibles gracias a una encuesta realizada en la ciudad de Maceió, sobre violencia contra la mujer y Atención Primaria de Salud. Se entrevistó a tres usuarios varones de una Unidad Básica de Salud (UBS), invitados en base a sus observaciones diarias. Las entrevistas fueron transcritas, divididas en categorías y analizadas a partir del marco teórico de la perspectiva de género feminista en interfaz con las Prácticas Discursivas y Producción de Sentidos. Aquí se traen dos categorías que discuten cómo los hombres reconocen (o no) las relaciones desiguales de poder que estructuran la sociedad y el reflejo en las prácticas de violencia contra las mujeres. De aquí se percibe la necesidad de la inclusión de los hombres en las discusiones sobre la violencia contra las mujeres, bajo una mirada crítica, situada y analítica de la categoría de género.(AU)
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Humanos , Masculino , Adulto , Persona de Mediana Edad , Atención Primaria de Salud , Violencia contra la Mujer , Masculinidad , Identidad de GéneroRESUMEN
SUMMARY: This study aimed to consolidate data regarding body height, body weight, body mass index, and nutrition status of the entire young male population from the Municipality of Bijelo Polje in order to estimate trends from 1979 to 1987. The sample of respondents includes 10,954 young males divided into nine groups. The measurement sample includes body height, body weight, and body mass index based on two previous measures. The descriptive statistics were expressed as a mean and standard deviation for each variable, while the analysis of nutrition status was done based on body mass index (underweight, normal weight, pre-obese, obese). The results showed that a secular trend in the observed study period is not visible regarding body height, body weight, and body mass index. The contribution of this study is reflected in the fact that there were no previously published data for this period and this municipality; the data can significantly aid in monitoring the secular trends throughout Montenegro.
RESUMEN: Este estudio tuvo como objetivo consolidar los datos sobre la altura corporal, el peso corporal, índice de masa corporal y el estado nutricional de toda la población masculina joven del Municipio de Bijelo Polje con el fin de estimar las tendencias de 1979 a 1987. La muestra de encuestados incluyó 10.954 hombres jóvenes divididos en nueve grupos. Las mediciones incluyeron la altura corporal, el peso corporal y el índice de masa corporal basado en dos medidas anteriores. Las estadísticas descriptivas se expresaron como media y desviación estándar para cada variable, mientras que el análisis del estado nutricional se realizó con base en el índice de masa corporal (bajo peso, peso normal, pre-obesidad, obesidad). Los resultados mostraron que una tendencia secular en el período de estudio observado no es visible con respecto a la altura corporal, el peso corporal y el índice de masa corporal. La contribución de este estudio está basada en que no existían datos publicados previamente para este período y en este municipio; los datos pueden ayudar significativamente a monitorear las tendencias seculares en todo Montenegro.
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Humanos , Masculino , Adolescente , Estatura , Peso Corporal , Índice de Masa Corporal , Estado Nutricional , Antropometría , Encuestas y Cuestionarios , MontenegroRESUMEN
Introduction: Effective control of Aedes aegypti will reduce the frequency and severity of outbreaks of dengue, chikungunya, and Zika; however, control programs are increasingly threatened by the rapid development of insecticide resistance. Thus, there is an urgent need for novel vector control tools, such as auto-dissemination of the entomopathogenic fungi Metarhizium anisopliae and Beauveria bassiana. The aim of this study was to estimate contact rates of M. anisopliae-exposed males with wild female Ae. aegypti. As a control the contact rates of untreated males with wild females was contrasted. Methods: The study was conducted in Reynosa, Mexico. The treatment and control households (n = 15 per group) were geographically separated by an arid and hot area that naturally prevented the flight of males between arms. In each control household, 40 M. anisopliae-exposed male Ae. aegypti were released per week for 8 weeks (specimens were exposed to a concentration of 5.96 × 107 conidia/cm2 for 24 h; n = 4,800 males). In each control household, 40 untreated males were released per week for 8 weeks (n = 4,800 males). All specimens were dust-marked prior to release. Mosquito abundance was monitored with human landing collections, and captured Ae. aegypti were examined for any dust-marking. Results: In the treatment households, the contact rate of Ae. aegypti females with marked, fungus-treated males was 14% (n = 29 females marked from 197). Where in the control households, the contact rate of females with marked, untreated males was only 6% (n = 22 marked from 365). In the treatment households the recapture rate of released males was at 5% and higher than that for the control households (which was 2%). Auto-dissemination of M. anisopliae from infected males to female Ae. aegypti was demonstrated through the recovery of an infected female from the floor of a household. Conclusions: Overall, the contact rate between M. anisopliae-infected males with the natural female population was 60% higher than for the control group of healthy males. The results provide further support to the release of fungus-exposed males as a potentially useful strategy against Ae. aegypti, though further research is required.
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Aedes , Metarhizium , Infección por el Virus Zika , Virus Zika , Animales , Femenino , Humanos , Masculino , México , Control de Mosquitos , Mosquitos VectoresRESUMEN
OBJECTIVE: The objective of this study is to study association between testosterone and diabetes in Kashmiri males. METHODS: A total of 300 males with Type 2 diabetes visited an outpatient and inpatient clinic at Shri Maharaja Hari Singh (SMHS) hospital, Srinagar, J&K India. The blood sugar and HbA1c, which are the markers of diabetes, and sérum testosterone levels were measured. The blood samples from both the cases and controls were collected. RESULTS: Out of 300 subjects, 42% had a testosterone deficiency. A relationship between type 2 diabetic males and healthy males was observed, and testosterone levels were determined to be significantly lower among diabetic males (p < 0.001) when compared to healthy males. Then, we compared diabetic markers among testosterone deficient and normal testosterone level groups; the mean fasting plasma glucose (p = 0.0019) and glycated haemoglobin (HbA1c; p = 0.0449) levels were significantly higher in the testosterone deficient group than in the control group. To elucidate the relationship between the serum total testosterone level and fasting plasma glucose and HbA1c values, Pearson's correlation test was performed. Fasting plasma glucose levels (r = -0.252, p = 0.001) and HbA1c values (r = -0.697, p = 0.001) showed a significant negative correlation with serum testosterone levels among diabetic males. CONCLUSION: This study shows that diabetes causes low testosterone levels among males, and lower testosterone levels can act as a marker for diabetes. Thus, with timely intervention, mortality and co-morbidity associated with diabetes can be prevented.
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Diabetes Mellitus Tipo 2 , Glucemia , Hemoglobina Glucada/análisis , Humanos , India , Masculino , TestosteronaRESUMEN
OBJECTIVE: To investigate perspectives of diabetes, nutrition, and health among underrepresented Mexican-origin males and elucidate on contributing factors of type 2 diabetes disparities. RESEARCH DESIGN: Audio-recorded, semi-structured interviews were conducted with 15 native Spanish-speaking, Mexican-origin males. Men were between the ages of 40 and 64 and at risk for type 2 diabetes-defined as > 40 years of age, BMI > 25, and sedentary over the last 3 months. Data collected included clinical measures (height, weight, waist circumference, blood pressure) and demographic characteristics (years living in the U.S., marital status, employment, occupational physical activity, income, educational attainment, and average physical activity levels). The audio recordings, each lasting approximately 60 min, were transcribed verbatim and underwent three-cycle coding with analysis for codebook formation, categorization, and thematic extraction. RESULTS: Barriers to engaging in health behaviors among Mexican-origin males include poor understanding of diabetes and nutrition, unreliable sources of health information, and socioeconomic status. Enablers of health neglect include intense perceptions of diabetes severity and a reactive health culture rooted in medical machismo and valemadrismo. Perspectives of personal responsibility and the desire to learn through culturally specific recommendations detail potential facilitators of health behaviors. CONCLUSION: The data convey a network of sociocultural factors that inhibit health prioritization and promote disease misconceptions among Mexican-origin males. Pragmatic, culturally tailored education represents serviceable strategies for health promotion and diabetes prevention. These findings explicate cultural considerations for educators and clinicians seeking optimization of programs and clinical interactions with Mexican-origin men.
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Diabetes Mellitus Tipo 2/etnología , Conocimientos, Actitudes y Práctica en Salud/etnología , Americanos Mexicanos/psicología , Adulto , Disparidades en el Estado de Salud , Humanos , Masculino , Americanos Mexicanos/estadística & datos numéricos , México/etnología , Persona de Mediana Edad , Investigación Cualitativa , Medición de Riesgo , Factores de RiesgoRESUMEN
PURPOSE: Considering the increased cancer patient survivorship, the focus is now on addressing the impacts of treatment on quality of life. In young people, altered reproductive function is a major issue and its effects in young males are largely neglected by novel research. To improve clinician awareness, we systematically reviewed side effects of chemotherapy for Hodgkin lymphoma (HL) in young males. METHODS: The review was prospectively registered (PROSPERO N. CRD42019122868). Three databases (Medline via PUBMED, SCOPUS, and Cochrane Library) were searched for studies featuring males aged 13-51-years who underwent chemotherapy for HL using ABVD (Adriamycin® (doxorubicin), bleomycin, vinblastine, and dacarbazine) or BEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisolone) regimens. These chemotherapy regimens were compared against each other using sperm characteristics, FSH, and inhibin B levels to measure fertility levels. RESULTS: Data were extracted from five studies featuring 1344 patients. 6 months post-ABVD saw marked deterioration in sperm count, further reduced by more cycles (P = 0.05). Patients treated with BEACOPP rather than ABVD were more prone to oligospermia. Receiving fewer cycles of both regimens increased the likelihood of sperm production recovering. Patients treated with 6-8 cycles of BEACOPP did not recover spermiogenesis. CONCLUSIONS: ABVD and BEACOPP regimens significantly reduce fertility function to varying effects depending on treatment duration. ABVD temporarily causes significant reductions in male fertility, whereas BEACOPP's effects are more permanent. Therefore, clinicians should discuss fertility preservation with male patients receiving infertility-inducing gonadotoxic therapy. Further high-quality studies are required to more adequality describe the risk to fertility by chemotherapy.