Complications and clinical outcomes with minimally invasive plate osteosynthesis (MIPO) technique for midshaft clavicle fractures: a systematic review and meta-analysis.

Background: Clavicle fractures are among the most common upper limb fractures in adults, with the midshaft region being the most frequently affected site. Minimally invasive plate osteosynthesis (MIPO) has emerged as an alternative to the traditional open reduction and internal fixation (ORIF) technique, offering potential advantages. The purpose of this study was to conduct a systematic review to explore the results of this technique in the existing literature, with emphasis on the occurrence of surgical complications and functional outcomes and also to provide a comprehensive comparison of MIPO and ORIF in the management of midshaft clavicle fractures. Methods: We conducted a systematic review to evaluate the complication incidence and clinical outcomes of MIPO for midshaft clavicle fractures. We searched PubMed/Medical Literature Analysis and Retrieval System Online (MEDLINE), Scopus, the Cochrane Database of Controlled Trials, and the Cochrane Database of Systematic Reviews databases without language or date restrictions. Studies focusing on midshaft clavicle fractures treated with MIPO were included, while other clavicle fractures and nonclinical studies were excluded. The risk of bias was assessed using the Methodological Index for Nonrandomized Studies criteria and the Risk of Bias Tool 2 Cochrane tool. Data synthesis included qualitative analysis, and if applicable, quantitative analysis and meta-analysis. Adherence to Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines ensured reporting quality. Results: A total of 107 studies were initially identified, after applying inclusion and exclusion criteria, 22 studies were included for data extraction. These studies involved the evaluation of 714 clavicles treated with the MIPO technique. Of the 714 MIPO cases, 11 cases of implant failure, 5 nonunions, 2 infections, and 28 cases with neurological impairment were observed. Quantitative analysis comparing MIPO with ORIF revealed that MIPO had significantly shorter surgery time (mean difference -12.95, 95% confidence interval [-25.27 to -0.63], P = .04) and lower occurrence of numbness (odds ratio 0.29, 95% CI [0.15-0.56], P = .0002) compared to ORIF. Time to bone union, functional outcomes, and other complications were similar between MIPO and ORIF at the final follow-up. An overall moderate risk of bias was found across the studies. Conclusion: The MIPO technique yields good and comparable results to ORIF for midshaft clavicle fractures. Additionally, the MIPO technique may offer advantages such as reduced surgical time and lower chances of neurological impairment.

Surgical fixation of displaced midshaft clavicular fractures with precontoured plates in adolescents. / Tratamiento de fracturas mediodiafisarias de clavícula con placas precontorneadas en adolescentes.

BACKGROUND: The use of plate fixation to treat displaced midshaft clavicular fractures in adults reduces complications and residual shoulder disability. New features of the precontoured locking plates have been shown to reduce the need for hardware removal in adults. There is a lack of studies evaluating surgical fixation of displaced clavicular fractures with precontoured plates in adolescents. We evaluate outcomes and complications of adolescents with displaced midshaft clavicular fractures treated with precontoured locking plates. MATERIALS AND METHODS: 40 adolescents with displaced midshaft clavicular fractures were surgically treated from January 2010 to May 2017. Outcomes were evaluated using the Constant score, the 11- item version of the Disabilities of Arm, Shoulder and Hand (QuickDASH) questionnaires, and radiographs, and a visual analog scale. Return-to-sport rate, level achieved, and complications were recorded. RESULTS: Mean follow-up was 50 months (18 - 108 months). Constant, Quick-DASH, and visual analog scale scores were 95.6, 2.8 and 0.5 points, respectively. 100% of adolescents returned to sports at the same level they had before injury. Mean time to return was 69 days and 95% of patients were able to return before 12 weeks. Complication rate was 12.5%, 3 patients (7.5%) required hardware removal. CONCLUSIONS: Adolescents with displaced midshaft clavicular fractures treated with precontoured locking plates exhibited satisfactory outcomes and low complication rate. Compared to other reports, this study had lower rates, anatomic plates might reduce hardware-related complications.

TREATMENT OF MIDSHAFT CLAVICLE FRACTURE WITH SUPERIOR PLATE PLACEMENT.

OBJECTIVE: To evaluate the late clinical and radiological results of patients had locking plate anatomically compatible from superior surface and muscle cover on plate due to clavicle mid-region. MATERIALS AND METHODS: Forty patients were included retrospectively. Patients had a routine right shoulder anterior posterior graph after examination. The results were assessed by returning to the patient's daily activities, Constant score, the Disability of the Arm, and Shoulder and Hand scoring, followed by radiological and clinical examination. RESULTS: Fourteen (35%) patients were female and 26 (65%) were male. The mean age was 36.2 years. Twenty-six patients had right clavicle fracture and 14 patients had left. Twenty-three fractures were type 2B1 and 17 fractures were type 2B2. Mean follow-up time was 36.4 months. Radiologic union was at a mean of 9.1 ± 1.3 weeks. All patients had excellent results. The mean Constant score was 97.2 ± 1.8, the mean Disability of the Arm, and Shoulder and Hand score was 3.8 ± 2.4. CONCLUSION: It is possible to obtain complete union with high patient satisfaction by avoiding the complications and difficulties of the conservative treatment with the use of the anatomically compatible locking plates in superior fixation and our surgical dissection. Level of Evidence III, Retrospective Case controlled study.

OBJETIVO: Avaliar os resultados clínicos e radiológicos tardios dos pacientes com placa óssea de trava anatomicamente compatível com a superfície superior e a cobertura muscular na placa devido à região média da clavícula. MATERIAIS E MÉTODOS: Quarenta pacientes foram incluídos retrospectivamente. Os pacientes apresentaram um gráfico ântero-posterior de rotina do ombro direito após o exame. Os resultados foram avaliados retornando às atividades diárias do paciente, escore de Constant, incapacidade do braço e escores de ombro e mão, seguidos de exame clínico e radiológico. RESULTADOS: Quatorze (35%) pacientes eram do sexo feminino e 26 (65%) do sexo masculino. A idade média foi de 36,2 anos. Vinte e seis pacientes tiveram fratura da clavícula direita e 14 pacientes saíram. Vinte e três fraturas foram do tipo 2B1 e 17 fraturas do tipo 2B2. O tempo médio de acompanhamento foi de 36,4 meses. A união radiológica foi em média de 9,1 ± 1,3 semanas. Todos os pacientes tiveram excelentes resultados. A pontuação média constante foi de 97,2 ± 1,8, a média de incapacidade do braço e a pontuação do ombro e da mão foi de 3,8 ± 2,4. CONCLUSÃO: É possível obter união completa com alta satisfação do paciente, evitando as complicações e dificuldades do tratamento conservador com o uso das placas ósseas de trava anatomicamente compatíveis na fixação superior e na nossa dissecção cirúrgica. Nível de evidência III, Estudo retrospectivo controlado por caso.

Treatment of midshaft clavicle fracture with superior plate placement / Tratamento para fratura da diáfise da clavícula com inserção de placa óssea superior

ABSTRACT Objective: To evaluate the late clinical and radiological results of patients had locking plate anatomically compatible from superior surface and muscle cover on plate due to clavicle mid-region. Materials and Methods: Forty patients were included retrospectively. Patients had a routine right shoulder anterior posterior graph after examination. The results were assessed by returning to the patient's daily activities, Constant score, the Disability of the Arm, and Shoulder and Hand scoring, followed by radiological and clinical examination. Results: Fourteen (35%) patients were female and 26 (65%) were male. The mean age was 36.2 years. Twenty-six patients had right clavicle fracture and 14 patients had left. Twenty-three fractures were type 2B1 and 17 fractures were type 2B2. Mean follow-up time was 36.4 months. Radiologic union was at a mean of 9.1 ± 1.3 weeks. All patients had excellent results. The mean Constant score was 97.2 ± 1.8, the mean Disability of the Arm, and Shoulder and Hand score was 3.8 ± 2.4. Conclusion: It is possible to obtain complete union with high patient satisfaction by avoiding the complications and difficulties of the conservative treatment with the use of the anatomically compatible locking plates in superior fixation and our surgical dissection. Level of Evidence III, Retrospective Case controlled study.

RESUMO Objetivo: Avaliar os resultados clínicos e radiológicos tardios dos pacientes com placa óssea de trava anatomicamente compatível com a superfície superior e a cobertura muscular na placa devido à região média da clavícula. Materiais e Métodos: Quarenta pacientes foram incluídos retrospectivamente. Os pacientes apresentaram um gráfico ântero-posterior de rotina do ombro direito após o exame. Os resultados foram avaliados retornando às atividades diárias do paciente, escore de Constant, incapacidade do braço e escores de ombro e mão, seguidos de exame clínico e radiológico. Resultados: Quatorze (35%) pacientes eram do sexo feminino e 26 (65%) do sexo masculino. A idade média foi de 36,2 anos. Vinte e seis pacientes tiveram fratura da clavícula direita e 14 pacientes saíram. Vinte e três fraturas foram do tipo 2B1 e 17 fraturas do tipo 2B2. O tempo médio de acompanhamento foi de 36,4 meses. A união radiológica foi em média de 9,1 ± 1,3 semanas. Todos os pacientes tiveram excelentes resultados. A pontuação média constante foi de 97,2 ± 1,8, a média de incapacidade do braço e a pontuação do ombro e da mão foi de 3,8 ± 2,4. Conclusão: É possível obter união completa com alta satisfação do paciente, evitando as complicações e dificuldades do tratamento conservador com o uso das placas ósseas de trava anatomicamente compatíveis na fixação superior e na nossa dissecção cirúrgica. Nível de evidência III, Estudo retrospectivo controlado por caso.

Sex determination using morphometric and morphological dimensions of the clavicle within the KwaZulu-natal population / Determinación de sexo dentro de la población KwaZulu-natal mediante el uso de dimensiones morfométricas y morfológicas de la clavícula

Sex determination plays an essential role in forensic anthropology in the identification of an individual from skeletal remains. The aim of the study was to determine sex of an individual using the clavicle in a KwaZulu-Natal population. Various morphometric and morphological parameters were measured using 100 clavicles of known sex (66 male and 34 female) and age (range 25­95 years). The mean maximum length, mid-shaft circumference and maximum breadth of the sternal and acromial ends of the male clavicles were greater in females. However, the mean medial curve of the clavicle was greater in females than in males on both sides, and on the right side the female clavicles also had a greater mean lateral curve than the males. The maximum length and mid-shaft circumference alone could be used to predict sex with an accuracy of 89 %. Therefore, the provision of morphometric data pertaining to the clavicle may assist forensic investigators, anthropologists and anatomists to sex the clavicle.

La determinación del sexo juega un papel esencial en la antropología forense e identificación de un individuo con restos óseos. El objetivo fue determinar el sexo de un individuo mediante la clavícula en una población KwaZulu-Natal. Se midieron varios parámetros morfométricos y morfológicos utilizando 100 clavículas (66 hombres y 34 mujeres) con un rango etario entre 25­95 años. La longitud máxima media, circunferencia media del eje y la amplitud máxima de los extremos esternal y acromial de las clavículas de los hombres fueron mayores que en las mujeres. Sin embargo, la curva medial media de la clavícula fue mayor en mujeres que en hombres en ambos lados, y en el lado derecho las mujeres también tenían una curva lateral media de las clavículas mayor que en los hombres. La circunferencia máxima y la circunferencia media del eje por sí solas podrían ser utilizadas para predecir el sexo con una precisión de 89 %. Por tanto, la información de datos morfométricos relativos a la clavícula pueden ayudar a los investigadores forenses, antropólogos y anatomistas en la determinación del sexo.

Tratamiento con placa precontorneada bloqueada de fracturas desplazadas del tercio medio de la clavicula / Precontoured locking plate treatment for displaced midshaft clavicle fractures

Introducción: El objetivo de este trabajo es analizar los resultados de un grupo de pacientes con fracturas mediodiafisarias desplazadas de clavícula tratadas con placa precontorneada bloqueada. Se analizaron la tasa de consolidación ósea, los resultados funcionales y las complicaciones. Materiales y Métodos: Cuarenta y seis fracturas de clavícula desplazadas de tipo 2B de Edimburgo fueron tratadas con placa bloqueada precontorneada. Los pacientes eran 36 hombres (uno con fractura bilateral) y nueve mujeres, con una edad promedio de 33 años (rango 17-56). Los pacientes fueron evaluados con radiología y el puntaje de Constant, el test QuickDASH y la escala analógica visual para dolor. Resultados: El seguimiento promedio fue de 30 meses (rango 12-46). Cuarenta y cinco fracturas consolidaron y una no. El puntaje de Constant promedio fue de 96 (rango 56-100) y el de QuickDASH promedio, 2 (rango 0-32). El dolor en el seguimiento fue de 0,3 puntos (rango 0-6). Se registraron 10 complicaciones en nueve pacientes (21%), aunque solo tres (6,5%) fueron consideradas mayores. En siete pacientes (15%), se retiró la placa por intolerancia (uno de ellos fue el paciente con mala consolidación, se registró como segunda complicación en el mismo paciente). Conclusiones: La reducción y estabilización de las fracturas desplazadas del tercio medio de la clavícula con placas precontorneadas y bloqueadas son un tratamiento eficaz con un bajo índice de complicaciones mayores relacionadas, a veces, con errores técnicos.

Introduction: The aim of this paper is to analyze the results in a group of patients with displaced diaphyseal fractures treated with precontoured clavicle locking plate. The rate of bone healing, functional outcome and complications were analyzed. Methods: Forty-six displaced clavicle fractures (Edinburgh type 2B) were treated with precontoured locking plate. Thirty- six were men (one with bilateral fracture) and 9 were women, with an average age of 33 years (range 17-56). Patients were assessed with radiology and the Constant score, the QuickDASH test, and the visual analogue scale for pain. Results: The average follow-up was 30 months (range 12-46). Forty-five fractures healed and one did not. The Constant score averaged 96 points (range 56-100) and the QuickDASH test averaged 2 points (range 0-32). Pain was 0.3 points (range 0-6). There were 10 complications in 9 patients (21%), but only three (6.5%) were considered major. In 7 patients (15%) the plate had to be removed due to intolerance (one of them was a patient with malunion, registering as a second complication in the same patient). Conclusions: The reduction and stabilization of displaced midshaft fractures of the clavicle with precontoured clavicle locking plate is an effective treatment with a low rate of major complications, sometimes related to technical errors.

Operative versus nonoperative treatment for displaced midshaft clavicle fractures: a meta-analysis based on current evidence

Literature searches of the Cochrane Library, PubMed, EMBASE, Web of Science, LILACS, China National Knowledge Infrastructure, and Wanfang Data databases were performed from 1966 to September 2014. Only randomized and quasi-randomized controlled clinical trials comparing operative and nonoperative treatments for displaced midshaft clavicle fractures were included. Data collection and extraction, quality assessment, and data analyses were performed according to the Cochrane standards. Thirteen studies were considered in the meta-analysis. Constant scores and the Disabilities of the Arm, Shoulder and Hand scores were improved in the operative fixation group at a follow up of one year or more. The nonunion and symptomatic malunion rates were significantly lower in the operative group. Additionally, the nonoperative group had a higher likelihood of neurological symptoms compared with the operative group. A significantly higher risk of complications was found in patients treated conservatively than in those who underwent operative fixation. However, when patients with nonunion and symptomatic malunion were excluded from the analysis, no significant differences in the complication rate were found. We concluded that based on the current clinical reports, operative treatment is superior to nonoperative treatment in the management of displaced midshaft clavicle fractures. However, we do not support the routine use of primary operative fixation for all displaced midshaft clavicle fractures in adults.

Surgical treatment of displaced midshaft clavicular fractures with precontoured plates.

BACKGROUND: Plate fixation of displaced midshaft clavicular fractures has been shown to decrease nonunion, symptomatic malunion, and residual shoulder disability compared with nonoperative treatment. However hardware-related complications are a problem. The new features of the precontoured locking plates may reduce the need for hardware removal, thus maintaining the advantages of plate fixation. This study evaluated the clinical outcomes of patients with displaced midshaft clavicular fractures treated with precontoured locking plates. MATERIALS AND METHODS: From November 2008 to December 2012, we surgically treated 72 patients with displaced midshaft clavicular fractures. We retrospectively evaluated 68 patients who underwent 68 interventions. Postoperative functional outcomes were assessed with the Constant score, the 11-item version of the Disabilities of Arm, Shoulder and Hand (QuickDASH) questionnaire, and radiographs. Pain was subjectively assessed with a visual analog scale. Complications were recorded. Patients were asked if they were able to return to their previous employment level. RESULTS: The mean follow-up period was 23.6 ± 10.7 months. The average values of the Constant, QuickDASH, and visual analog scale scores were 97.8, 1.8, and 0.4 points, respectively. At the last follow-up, 98.5% were able to return to their regular work. Of 15 complications (22.1%) that occurred, only 3 were considered as major: 1 subclavian vein extrinsic compression, 1 nonunion, and 1 hardware loosening. Hardware removal was required in 9 patients (13.2%). CONCLUSIONS: Satisfactory clinical results with a low rate of complications were achieved with precontoured locking plates for displaced midshaft clavicular fractures and a low rate of hardware removal compared with traditional plates.