RESUMEN
INTRODUCTION: Vitamin D deficiency during pregnancy may lead to many health problems by negatively affecting the metabolism of the newborn and the mother, such as infantile rickets, poor fetal and neonatal growth and development, gestational diabetes, and preeclampsia. We aimed to investigate the levels and clinical results of vitamin D in preeclamptic mothers and their babies. METHODS: The study group consisted of 42 preeclamptic mothers, and their babies diagnosed with preeclampsia according to the International Society for the Study of Hypertension in Pregnancy (ISSHP) criteria, while the control group consisted of 49 healthy mothers and babies with similar gestational age and birth weight. All pregnant women participating in the study were routinely taking 1200 IU of vitamin D3 daily supplements. The cord blood vitamin D level of both groups of newborns was measured and the results were statistically compared. RESULTS: The birth week, weight, and height averages and APGAR score averages measured at the first minutes of the babies in the study group (preeclamptic mother babies) were statistically significantly lower than those of the babies in the control group (babies of healthy mothers) (p=0.001, p=0.001, p<0.001, p=0.004, respectively). Vitamin D and calcium levels of the mothers in the study group were lower than those of the mothers in the control group. When the infants were examined, only the level of vitamin D was statistically significantly lower in infants in the patient group (p<0.001, p<0.001, p=0.001, respectively). CONCLUSION: There is consistent evidence of an association between low vitamin D concentrations and adverse preeclampsia outcomes. Since vitamin D deficiency is more common in preeclamptic mothers and their infants, higher-dose vitamin D supplementation than routine may be recommended to the patients.
RESUMEN
A depressão que se inicia no puerpério é denominada como depressão pós-parto materna (DPP-M). A Síndrome de Down (SD) é uma cromossomopatia de alta incidência que ocasiona manifestações físicas, clínicas e intelectuais específicas. Objetivou-se descrever e comparar a frequência da DPP-M e de características sociodemográficas em mães de bebês com e sem SD e identificar possíveis preditores da DPP-M entre as variáveis sociodemográficas maternas, do bebê e familiares. Participaram 60 díades. Utilizou-se um questionário sociodemográfico e a Edinburgh Postpartum Depression Scale (EPDS). Os resultados não indicaram diferença significativa nos índices de DPP-M dos grupos, sendo esses mais elevados em mães de bebês sem SD. Comparando as variáveis sociodemográficas, o número de filhos e a idade do bebê foram maiores entre mães de bebês com SD e mais mães de bebês sem SD trabalham fora. A escolaridade, o tipo de família e a idade do bebê foram preditores para DPP-M.
Depression that initiates at puerperium is denominated maternal depressive post-partum disorder (M-DPPD). Down Syndrome (DS) is a chromosopathy of high incidence that occasionates specific physical, clinical and intellectual manifestations. This study aimed to describe and compare the frequency of M-DPPD and sociodemographic characteristics in mothers of babies with and without DS and identify possible predictors of M-DPPD among maternal, baby and family sociodemographic variables. Participants were 60 dyads. A sociodemographic questionnaire and the Edinburgh Postpartum Depression Scale (EPDS) were used. The results did not showed a significant difference in the M-DPPD indices of the groups, being these higher in mothers of infants without SD. Comparing the sociodemographic variables, the number of children and the age of the baby were higher among mothers of babies with SD and more mothers of babies without SD working outside. Schooling, family type, and baby's age were predictors for DPP-M.
La depresión que se inicia en el puerperio es denominada depresión posparto materna (DPP-M). El síndrome de Down es una cromosomopatía de alta incidencia que ocasiona un conjunto de manifestaciones físicas, clínicas y intelectuales específicas. Se objetivó describir y comparar la frecuencia de la DPP-M y de características sociodemográficas en madres de bebés con y sin SD e identificar posibles predictores de la DPP-M entre las variables sociodemográficas maternas, del bebé y familiares. Participaron 60 diadas. Se utilizó un cuestionario sociodemográfico y la Edinburgh Postpartum Depression Scale (EPDS). Los resultados señalaron que no hubo diferencia significativa en el índice de DPP-M de los grupos, siendo este índice más elevado en madres de bebés sin SD. Comparando las variables sociodemográficas, el número de hijos y la edad del bebé fueron mayores entre madres de bebés con SD y más madres de bebés sin SD trabajan fuera. La escolaridad, el tipo de familia y la edad del bebé fueron predictores para DPP-M.
