RESUMEN
We describe a group of 3 cases of invasive meningococcal disease that occurred in a military training camp in April 2011. All three patients were hospitalized. Ultimately, two patients recovered and one died. One patient had meningitis, one patient had septicemia and meningitis, and the other had no definite septicemia or meningitis. Neisseria meningitidis serogroup W-135 was detected in the serum and cerebrospinal fluid (CSF) of all patients by real-time polymerase chain reaction. In the one case of mortality, two strains were isolated from the patient's blood and CSF. Using multilocus sequence typing analysis, these strains were identified as a novel sequence type, ST-8912. Special attention is required for the meningococcal disease in military camp because the military personnels are in high risk of contact transmission.
Asunto(s)
Meningitis/diagnóstico , Neisseria meningitidis Serogrupo W-135/aislamiento & purificación , Sepsis/diagnóstico , ADN Bacteriano/sangre , ADN Bacteriano/líquido cefalorraquídeo , Electroforesis en Gel de Campo Pulsado , Humanos , Masculino , Meningitis/complicaciones , Meningitis/microbiología , Personal Militar , Tipificación de Secuencias Multilocus , Neisseria meningitidis Serogrupo W-135/genética , Reacción en Cadena en Tiempo Real de la Polimerasa , Sepsis/complicaciones , Sepsis/microbiología , Adulto JovenRESUMEN
We describe a group of 3 cases of invasive meningococcal disease that occurred in a military training camp in April 2011. All three patients were hospitalized. Ultimately, two patients recovered and one died. One patient had meningitis, one patient had septicemia and meningitis, and the other had no definite septicemia or meningitis. Neisseria meningitidis serogroup W-135 was detected in the serum and cerebrospinal fluid (CSF) of all patients by real-time polymerase chain reaction. In the one case of mortality, two strains were isolated from the patient's blood and CSF. Using multilocus sequence typing analysis, these strains were identified as a novel sequence type, ST-8912. Special attention is required for the meningococcal disease in military camp because the military personnels are in high risk of contact transmission.