RESUMEN
OBJECTIVE: The perform pre-clinical testing using optical design tools to simulate the optical quality of a smart artificial iris platform encapsulated in a scleral contact lens. These tools allow us to generate aniridia eye models and evaluate different metrics of visual quality and retinal illumination based on the aperture of the artificial iris based on liquid crystals. METHOD: The OCT imaging technique was used to measure the geometry of the anterior segment in a patient with aniridia and, from these data, the eye model was generated with the Zemax optical design program and specific programs developed in Matlab. Ocular aberrations were calculated and the visual function of the anirida eye model was evaluated in three scenarios: (i) without optical correction, (ii) with correction with a commercial scleral contact lens, and (iii) with correction with an optical lens. Intelligent contact based on artificial iris. RESULTS: Optical quality in patients with aniridia is limited by the magnitude of high-order aberrations. Conventional scleral contact lens design accurately corrects for blur but is unable to compensate for high-order ocular aberrations, especially spherical aberrations. The artificial iris-based smart contact lens design enables virtually all high-order aberrations to be compensated with active control of the pupillary diameter (activation of liquid crystal cells based on ambient lighting). In addition to minimizing high-order aberrations, reducing the pupil size would increase the depth of focus. CONCLUSIONS: This article demonstrates by means of optical simulations the concept of an intelligent artificial iris platform encapsulated in a scleral contact lens and its possible application in patients with aniridia. Furthermore, it allows us to anticipate possible visual results in clinical trials with healthy patients (after application of mydriatic agents) and in patients with aniridia. The results demonstrate a better visual quality and a decrease in retinal illumination.
Asunto(s)
Aniridia , Lentes de Contacto , Lentes Intraoculares , Aniridia/terapia , Humanos , Iris , Agudeza VisualRESUMEN
OBJECTIVE: To perform pre-clinical testing using optical design tools to simulate the optical quality of a smart artificial iris platform encapsulated in a scleral contact lens. These tools allow us to generate aniridia eye models and evaluate different metrics of visual quality and retinal illumination based on the aperture of the artificial iris based on liquid crystals. METHOD: The OCT imaging technique was used to measure the geometry of the anterior segment in a patient with aniridia and, from these data, the eye model was generated with the Zemax optical design program and specific programs developed in Matlab. Ocular aberrations were calculated and the visual function of the anirida eye model was evaluated in three scenarios: (i) without optical correction, (ii) with correction with a commercial scleral contact lens, and (iii) with correction with an optical lens. intelligent contact based on artificial iris. RESULTS: Optical quality in patients with aniridia is limited by the magnitude of high-order aberrations. Conventional scleral contact lens design accurately corrects for blur but is unable to compensate for high-order ocular aberrations, especially spherical aberrations. The artificial iris-based smart contact lens design enables virtually all high-order aberrations to be compensated with active control of the pupillary diameter (activation of liquid crystal cells based on ambient lighting). In addition to minimizing high-order aberrations, reducing the pupil size would increase the depth of focus. CONCLUSIONS: This article demonstrates by means of optical simulations the concept of an intelligent artificial iris platform encapsulated in a scleral contact lens and its possible application in patients with aniridia. Furthermore, it allows us to anticipate possible visual results in clinical trials with healthy patients (after application of mydriatic agents) and in patients with aniridia. The results demonstrate a better visual quality and a decrease in retinal illumination.
RESUMEN
a adaptación de lentes esclerales en el manejo del queratocono puede ser una buena alternativa. Objetivo: comparar la adaptación de lentes rígidos gas permeables esclerales en pacientes con queratocono, calculados matemáticamente con base en datos del visante oct (optical tomography coherence) y el método tradicional (ensayo y error). Materiales y métodos: se realizó investigación observacional descriptiva. A ocho pacientes (16 ojos) con diagnóstico de queratocono se les adaptaron lentes de contacto rígidos esclerales, usando dos métodos de cálculo: el tradicional, de ensayo y error, y calculando los parámetros de los lentes mediante un modelo matemático, a partir de los datos de la topografía y la tomografía de alta resolución con visante oct. Con cada método se evaluó la agudeza visual, el número de pruebas necesarias para la adaptación final, el confort y la superficie ocular. Resultados: la agudeza visual dio igual en los métodos y la valoración de la superficie ocular presentó diferencias estadística (p < 0,05 según la prueba de rangos de Wilcoxon) y clínicamente significativas, siendo mejor el método del modelo matemático; igualmente, con el método de modelo matemático se logró mejor confort y menor número de pruebas que con el tradicional. Conclusiones: la utilización de la tecnología actual puede contribuir a mejorar las adaptaciones en lentes esclerales y optimizar tiempo y recursos.
itting scleral lens in management of keratoconus can be a good alternative. Objectives: To compare the adaptation of rigid gas permeable scleral lens in patients with keratoconus, mathematically calculated based on data from visante oct (optical tomography coherence) and the traditional method (trial and error). Materials and methods: Descriptive observational research was carried out. Rigid scleral contact lenses were adapted to eight patients (16 eyes) diagnosed with keratoconus, using two calculation methods: the traditional trial and error and calculating the parameters of the lens using a mathematical model, based on the topography data and the high-resolution ct with visante oct. With each method, the visual acuity was evaluated, as well as the number of tests needed for the final adaptation, the comfort and the ocular surface. Results: Visual acuity was the same in both methods and the assessment of the ocular surface presented statistical differences (p < 0.05 according to the Wilcoxon rank test) and clinically significant, where the method of mathematical modeling was better; likewise, the method of mathematical modeling achieved better comfort and a lower number of tests than the traditional. Conclusions: Using current technology can contribute to improve scleral lenses adaptation and to optimize time and resources.
