RESUMEN
BACKGROUND: Retraining programs in vocational rehabilitation are often characterized by a low level of physical activity, even when targeting jobs with primarily physical demands. They might therefore be accompanied by a decline in functional capacity if the lack of physical activity is not compensated by increased activity during leisure time. The implementation of a work-related exercise app might be a promising approach to promoting a return to work in vocational rehabilitation. We developed the "WORKout-app" which provides exercise plans based on a comparison of the physical demands of the retraining profession and the current functional capacity. OBJECTIVE: The aim of this study is to examine the effects of app-based exercise during vocational rehabilitation on perceived work ability (primary outcome), occupational self-efficacy, days of sick leave, and return to work (secondary outcomes). METHODS: We conducted a cluster-randomized controlled trial with 2 arms (intervention: WORKout-app vs control: treatment as usual) in 4 cohorts of 5 vocational rehabilitation centers in Germany. Participants are nested within retraining classes per vocational rehabilitation center and per cohort assigned to either the intervention condition or the control condition. The target sample size at the participant level is 598. Measurement time points include baseline, the end of rehabilitation, 3 months after the end of rehabilitation, and 6 months after the end of rehabilitation. Linear and generalized linear mixed-effects models are performed to test for treatment differences in outcomes. RESULTS: This study is funded by the German Federal Pension Insurance. The trial is registered with the German Clinical Trials Register (DRKS00030775) and approved by the Ethics Committee of the German Sport University Cologne (145/2022). CONCLUSIONS: The findings of the study will inform researchers and practitioners about the effectiveness of an exercise app developed to counteract the effects of physical inactivity during vocational rehabilitation. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/50200.
RESUMEN
Several Orobanche medicinal plants sometimes served as alternative sources of Cistanches Herba, attributing to the benefits such as tonifying kidney, strengthening tendons and bones. Among them, O. coerulescens, O. cernua and O. pycnostachya have been widely utilized in northern China for treatments of pains in the loins and knees, impotence, and spermatorrhea. However, their chemical profiles haven't been elucidated. In the present study, UHPLC-IT-TOF-MS was implemented to conduct in-depth chemome profiling of O. coerulescens, O. cernua and O. pycnostachya, aiming to achieve a comprehensive chemical characterization and to provide pronounced information for the quality control and clinical applications. An ACE Ultra-Core 2.5 Super C_(18)(3.0 mm×150 mm, 2.5 μm) column was deployed for chromatographic separations, and high-resolution MS~n spectra were recorded by IT-TOF-MS. Forty-eight components, in total, were observed, and thirty-eight ones were structurally annotated according to proposing mass fragmentation patterns, matching with relevant databases. Particularly, nine ones were confirmed by reference compounds. Overall, the chemical compositions of O. coerulescens and O. cernua are quite similar, and differences occur between O. pycnostachya and the prior two ones; primary chemical family is phenylethanoid glycosides, and several lignan glycosides as well as iridoid glycosides are also observed; the primary components include acteoside, isoacteoside, crenatoside and 2'-acetylacteoside, etc.
Asunto(s)
Masculino , China , Cistanche , Glicósidos , Orobanche , Plantas MedicinalesRESUMEN
O texto descreve o projeto IMBA: Integração de Pessoas com Deficiência no Mercado de trabalho e suas diversas aplicações bem sucedidas em diferentes organizações européias e sua iminente introdução no Brasil. IMBA é um procedimento de comparação de perfis de trabalho e de documentação para a capacitação justa da força de trabalho. Com o IMBA as exigências de trabalho e as capacidades humanas podem ser descritas, definidas e comparadas entre si consistentemente. O IMBA considera, desta forma, de maneira especial as necessidades dos mais velhos, de pessoas com necessidades especiais numa visão nova e mais eficiente. O IMBA foi desenvolvido e testado pelo iqpr, Instituto para a Segurança de Qualidade na Prevenção e Reabilitação, e as organizações parceiras Universidade de Siegen e Munda GmbH, Essen, com o apoio financeiro do Ministério Alemão do Trabalho e Assuntos Sociais. A equipe de desenvolvimento é interdisciplinar, formada por cientistas do trabalho, médicos, psicólogos e cientistas do esporte. O IMBA tem atualmente uma versão impressa e outra em software chamada MARIE. O IMBA pode também ser aplicado no contexto da educação profissional e da prevenção, da reabilitação e da integração além de fornecer uma ferramenta adequada para a elaboração do status e da documentação de intervenção. Dependendo do problema pode ser introduzido no âmbito de medidas médicas para colocação inicial de pessoas no trabalho, quando há exigências específicas de habilidades e dimensões. Em suma, o IMBA é uma ferramenta que pode ser utilizada de modo a ajudar o indivíduo dentro de um processo de reabilitação e de integração no trabalho.
The text describes the Project IMBA: Integration of people with disabilities into the workplace and its several successful applications in different European organizations and its imminent introduction in Brazil. IMBA is a profile comparison and documentation procedures for the equitable workforce capacity. With IMBA can job requirements and human capabilities through consistent, defined characteristics be described and compared directly with each other. IMBA considers in this special way the needs of elderly, disabled people a new and more efficient vision. IMBA has been developed and tested by iqpr, Institute for Quality Security in the Prevention and Rehabilitation, and partner organizations University of Siegen and Munda GmbH, Essen, with financial support of the German Ministry of Labour and Social Affairs. The development team consisted of an interdisciplinary team made up of work scientists, physicians, psychologists and sports scientists. IMBA has currently a paper version and a software version called MARIE. Otherwise IMBA can be used in the context of professional education and prevention, rehabilitation and integration and provides an appropriate tool to status and documentation course of intervention. Depending on the problem it may also integrate within the scope of medical measures for early implementation when job-specific skill requirements and dimensions e.g. to reintegrate into the workplace, in the medical rehabilitation process. IMBA is to be applied in a way to help the individual within a necessary rehabilitation and integration process.