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1.
BMC Oral Health ; 24(1): 436, 2024 Apr 10.
Artículo en Inglés | MEDLINE | ID: mdl-38600486

RESUMEN

The anatomy of furcation favours the bacterial retention and makes periodontal debridement as well as oral hygiene procedures difficult. Teeth that have lost attachment to a level of the furcation are said to have a furcal invasion or furcation involved.Involvement of furcation in a multi-rooted tooth poses a very different type of clinical situation in terms of establishment of diagnosis, determination of prognosis and of course planning the treatment modality.The present study was carried out on 200 selected extracted human first and second permanent molar teeth based on a predefined criteria. Teeth with prosthetic crowns, fused or fractured roots, those not fully developed, grossly carious or heavily restored at the cementoenamel junction (CEJ) were excluded from the study. The morphology of the root trunk was recorded by measuring various dimensions of the root trunk,including furcal angle and root trunk volume was calculated by using a custom made special apparatus. The furcation areas were debrided with different types of curettes in the market in order to see how best the instrument could be maneuvered in the furcation area. The data so obtained was statistically analysed using SPSS version 22. The highest root trunk volume and the longest root trunk length were found to be in the maxillary second molar. 48.60% furcations didn't allow instrument engagementof furcation area with standard area specific curettes. The proposal of inclusion of root trunk length (mm) is suggested in addition to classification of FI to have assess prognosis and appropriate treatment for of the involved tooth.


Asunto(s)
Defectos de Furcación , Raíz del Diente , Humanos , Raíz del Diente/anatomía & histología , Diente Molar/cirugía , Diente Molar/anatomía & histología , Cuello del Diente , Pronóstico , Biometría , Defectos de Furcación/cirugía , Defectos de Furcación/diagnóstico
2.
J Contemp Dent Pract ; 25(2): 160-167, 2024 Feb 01.
Artículo en Inglés | MEDLINE | ID: mdl-38514414

RESUMEN

AIM: Amnion and chorion membranes possess unique inherited biological properties that enhance wound healing and may accelerate periodontal regeneration. The present study aims to evaluate and compare the efficacy of amnion and chorion membranes in the treatment of furcation defects. MATERIALS AND METHODS: A total of 20 patients were selected and were randomly allocated to group I and group II with 10 subjects in each group. Amnion and chorion membranes are placental-derived membranes that accelerate regeneration by having natural growth factors with their antimicrobial and inflammation reduction properties. Group I was treated using bone grafting with decalcified freeze-dried bone allograft (DFDBA) and placement of amnion as a membrane for guided tissue regeneration (GTR) whereas group II was treated using bone grafting with DFDBA and placement of chorion as a membrane for GTR. The patients were followed for clinical and radiographic parameters and were evaluated between 3 and 6 months after surgery. RESULT: In intragroup comparison, a significant difference was evident in both the groups for all the clinical and radiographic parameters within the groups. (p = 0.01) This means both amnion and chorion membranes showed statistically significant regenerative efficacy. In intergroup comparison, the results show that all the clinical parameters and radiographic parameters show no significant difference between the groups. CONCLUSION: The amnion and chorion membranes had similar regenerative efficacy in combination with DFDBA in patients with buccal degree II furcation defects in mandibular molars. CLINICAL SIGNIFICANCE: The amnion and chorion membranes have shown significant improvement in clinical and radiographic parameters when used for the treatment of buccal degree II furcation defects in mandibular molars. How to cite this article: Mallapragda S, Gupta R, Gupta S, et al. Evaluation of Regenerative Efficacy of Amnion and Chorion Membrane in Treatment of Mandibular Molar Furcation Defects: A Clinico-radiographic Study. J Contemp Dent Pract 2024;25(2):160-167.


Asunto(s)
Defectos de Furcación , Embarazo , Humanos , Femenino , Defectos de Furcación/cirugía , Amnios/trasplante , Regeneración Tisular Guiada Periodontal/métodos , Placenta/cirugía , Diente Molar/cirugía , Trasplante Óseo/métodos , Corion/cirugía , Membranas Artificiales
3.
Int Endod J ; 57(5): 617-628, 2024 May.
Artículo en Inglés | MEDLINE | ID: mdl-38306111

RESUMEN

AIM: Conventional root resection in periodontally compromised furcation-involved maxillary molars requires preceding endodontic treatment and is therefore associated with loss of tooth vitality, higher invasiveness, treatment time and costs, and the risk of endodontic complications. Vital root resection (VRR) could overcome these disadvantages while establishing stable periodontal and endodontic conditions. This case series aimed to introduce the concept of one-stage VRR with radicular retrograde partial pulpotomy (VRRretro). SUMMARY: Seven vital maxillary molars with residual probing pocket depths (PPD) ≥ 6 mm and furcation ≥ class 2 of five patients with stage III/IV periodontitis were treated with VRRretro using mineral trioxide aggregate. Teeth with residual through-and-through furcations were additionally tunnelled. Follow-up up to 2.5 years postoperatively during supportive periodontal care included full periodontal status, percussion and thermal sensitivity testing. Periapical radiographs were obtained to rule out possible periradicular radiolucencies. All seven treated molars were in-situ at an average of 26.84 ± 5.37 months postoperatively and were clinically and radiographically inconspicuous independent of tooth position, the resected root, the need for tunnelling and the restorative status. The mean PPD on the seven treated molars was 4.02 ± 0.85 mm (6-10 mm) preoperatively and 2.62 ± 0.42 mm (3-4 mm) at the last follow-up. Clinical attachment level and bleeding on probing could also be decreased. The teeth showed no mobility over time and furcations class 2 were reduced to class 1 while the tunnelled furcations were accessible with interdental brushes. All molars reacted negatively to percussion and positively to thermal sensitivity testing. KEY LEARNING POINTS: In carefully selected cases considering patient- and tooth-related factors, VRRretro could be a promising treatment option to establish stable periodontal and endodontic conditions in furcation-involved maxillary molars while preserving tooth vitality.


Asunto(s)
Defectos de Furcación , Periodontitis , Humanos , Pulpotomía , Defectos de Furcación/cirugía , Periodontitis/complicaciones , Periodontitis/cirugía , Diente Molar/cirugía
4.
Clin Anat ; 37(3): 353-365, 2024 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-38348736

RESUMEN

Cervical enamel projections (CEPs) represent a unique developmental and anatomical anomaly wherein the enamel structure extends apically beyond the cemento-enamel junction of the tooth. In this scoping review, the existing literature on CEPs was evaluated to delineate their characteristics, prevalence, predilection for specific teeth and surfaces, clinical significance, and management approaches. Searches were conducted on MEDLINE (PubMed), Cochrane Library, and Embase databases using the keywords "enamel projection(s)" or "ectopic enamel." In total, 24 studies meeting inclusion criteria were included in the review. The prevalence of CEPs varied widely (8.3%-85.1%), predominantly manifesting as grade I or grade III. Mandibular first and second molars exhibited a higher incidence of CEPs, with a notable predilection for buccal surfaces. The consensus in most studies was that CEPs are associated with localized periodontal diseases. Recommendations inclined toward the removal of ectopic enamel during periodontal surgery to enhance periodontal attachment formation. However, decision-making should involve careful consideration of the benefits and drawbacks based on individual circumstances.


Asunto(s)
Defectos de Furcación , Humanos , Defectos de Furcación/complicaciones , Defectos de Furcación/cirugía , Diente Molar , Cuello del Diente/anomalías , Cuello , Esmalte Dental
5.
Cell Tissue Bank ; 25(1): 295-303, 2024 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-36627541

RESUMEN

Managing furcation defects constitutes a problem in successful periodontal therapy. Guided tissue regeneration (GTR) is the mainstay for the management of such defects but is expensive. This study makes use of indigenously prepared demineralized freeze-dried bone allograft (DFDBA) and amniotic membrane (AM) as a cost-effective alternative. The purpose of the study was to compare the clinical outcome of grade II and III furcation defects with and without using indigenous DFDBA and AM prepared at Central Tissue Bank, MAIDS. 18 systemically healthy patients with chronic periodontitis displaying either grade II or III furcation defects were treated with open flap debridement (OFD) + intramarrow penetration (IMP) (control group) and OFD + IMP + DFDBA + AM (test group). The clinical and radiographic parameters were recorded at 3 and 6 months postoperatively. All parameters were statistically analyzed. Both treatment modalities resulted in improvement in all clinical variables evaluated. Radiographic dimensions evaluating bone fill showed a statistically significant difference in the test group compared to the control group. Within the limitations of this study, data suggest GTR using indigenously prepared DFDBA and amniotic membrane to be an economical and viable option for treating furcation defects.


Asunto(s)
Periodontitis Crónica , Defectos de Furcación , Humanos , Defectos de Furcación/diagnóstico por imagen , Defectos de Furcación/cirugía , Amnios/trasplante , Periodontitis Crónica/cirugía , Regeneración Tisular Guiada Periodontal/métodos , Trasplante Óseo/métodos , Resultado del Tratamiento , Pérdida de la Inserción Periodontal/cirugía
6.
Hua Xi Kou Qiang Yi Xue Za Zhi ; 41(5): 582-591, 2023 Oct 01.
Artículo en Inglés, Chino | MEDLINE | ID: mdl-37805683

RESUMEN

Conventional periodontal regenerative surgery has limited effect on tooth with severe periodontitis-related alveolar bone defects. This article reported a case of regenerative treatment in severe distal-bone defect of mandibular first molar. The treatment involved applying 3D printing, advanced/injectable platelet-rich fibrin, and guided tissue-regeneration technology. After the operation, the periodontal clinical index significantly improved and the alveolar bone was well reconstructed.


Asunto(s)
Defectos de Furcación , Periodontitis , Fibrina Rica en Plaquetas , Humanos , Estudios de Seguimiento , Tecnología Digital , Defectos de Furcación/cirugía , Defectos de Furcación/tratamiento farmacológico , Regeneración Tisular Guiada Periodontal
7.
Adv Med Sci ; 68(2): 366-371, 2023 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-37757664

RESUMEN

Periodontitis is an infectious disease characterized by the inflammatory destruction of the tooth supporting tissues. In multi-rooted teeth, this process leads to periodontal destruction within furcations creating defects demanding in terms of treatment. Regeneration of class II furcation involvement, although possible, is considered an unpredictable procedure, especially in terms of the bone fill. The interest in wound healing improvement by additional use of autologous concentrates of growth factors remains high in many fields of dentistry. Platelet-rich fibrin (PRF) is a second-generation platelet concentrate and biomaterial. PRF forms a solid fibrin matrix, which is slowly remodeled comparable to the natural blood clot. Its utilization is associated with release of growth factors and glycoproteins over a long period of time. PRF activates alkaline phosphates, which show osteoblastic activity and this activation influences the bone formation. The aim of this review of randomized controlled trials (RCTs) was to evaluate the adjunctive use of platelet-rich fibrin in surgical treatment of furcation defects.


Asunto(s)
Defectos de Furcación , Fibrina Rica en Plaquetas , Humanos , Defectos de Furcación/cirugía , Cicatrización de Heridas
8.
Periodontol 2000 ; 92(1): 120-134, 2023 06.
Artículo en Inglés | MEDLINE | ID: mdl-37435999

RESUMEN

Regenerative periodontal surgical procedures are an important component in the treatment of advanced periodontitis. They aim to improve the long-term prognosis of teeth that are periodontally compromised by the presence of intrabony and/or furcation defects, resulting biologically in formation of root cementum, periodontal ligament, and alveolar bone and evidenced clinically by reduction of deep pockets to maintainable probing depths and/or improvements of vertical and horizontal furcation depth. Over the last 25 years, substantial clinical evidence has been accumulated to support the value of regenerative procedures in periodontally compromised dentitions. However, treatment success requires close attention to certain factors on the level of the patient, the tooth/defect, and the operator. Ignoring these factors in case selection, treatment planning, and treatment execution will increase the risk of complications that may jeopardize clinical success and may even be considered as treatment errors. Based on the currently available evidence from clinical practice guidelines, treatment algorithms, and on expert opinion, the present article provides an overview on the main factors, which influence the outcomes of regenerative periodontal surgery and gives recommendations on how to prevent complications and treatment errors.


Asunto(s)
Pérdida de Hueso Alveolar , Defectos de Furcación , Procedimientos Quirúrgicos Orales , Periodontitis , Humanos , Regeneración Tisular Guiada Periodontal/métodos , Resultado del Tratamiento , Periodontitis/cirugía , Pronóstico , Pérdida de Hueso Alveolar/cirugía , Defectos de Furcación/cirugía
9.
Clin Oral Investig ; 27(7): 3779-3786, 2023 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-37052671

RESUMEN

BACKGROUND: The relationship between the anatomy of the interradicular space and success in regenerative therapy of furcation defects is discussed in this paper. The goal of this retrospective, multicenter clinical study is to clinically evaluate the relationship between the interradicular conformation and regenerative therapy success with the use of a novel measurement method. METHODS: One hundred thirty-eight radiographs of mandibular molars with furcation defects that had been treated with regenerative therapy were collected from six clinical centers. Data on the type of therapy and clinical parameters before and after treatment (follow-up of at least 12 months) were collected. The radiographs (before surgery and at least 12 months postoperatively) were measured with a visual evaluation method by a blind operator using graphics software. RESULTS: Success, defined as a reduction in horizontal and vertical furcation involvement, decrease in probing depths, and increase in clinical attachment level, was statistically assessed on 138 regenerated molars sites and were related to clinical variables such as age, sex, center, and treatment. No correlation was found between success in regenerative therapy and the conformation of the interradicular space, measured with a visual ratio method and a standard linear measurement. At the univariate analysis, the parameters that had a correlation with success were center, extent of furcation involvement, treatment, and sex. The use of enamel matrix derivative (EMD) seemed to be the most favorable therapy, with increase in CAL gain and reduction of vertical or horizontal furcation involvement. CONCLUSIONS: The regenerative outcome was not significantly influenced by the anatomy of furcation. The center, the degree of furcation involvement, sex, and treatment (EMD) were significantly associated with higher success of periodontal regeneration.


Asunto(s)
Defectos de Furcación , Regeneración Tisular Guiada Periodontal , Humanos , Resultado del Tratamiento , Regeneración Tisular Guiada Periodontal/métodos , Defectos de Furcación/diagnóstico por imagen , Defectos de Furcación/cirugía , Estudios Retrospectivos , Pérdida de la Inserción Periodontal
10.
Medicina (Kaunas) ; 59(3)2023 Mar 15.
Artículo en Inglés | MEDLINE | ID: mdl-36984573

RESUMEN

Background and Objectives: Guided tissue regeneration, with or without a bone graft, is a modality for the treatment of furcation involvement. Because the direct application of a bone graft into the periodontal defect has drawbacks, such as the risk of microbial contamination and/or graft containment, a new modality of directly loading bone graft particles over the barrier membrane is now used. This study aimed to evaluate clinically and radiographically the effects of a two-layered membrane consisting of a layer of nanohydroxyapatite particles on a pericardium membrane in the treatment of stage III periodontitis, compared with direct application of a nanohydroxyapatite bone graft. Materials and Methods: Forty individuals with grade II furcation involvement were divided into two groups. Group I was treated with a two-layered membrane consisting of a pericardium membrane with nanohydroxy particles loaded onto its surface; group II was treated with direct application of a nano bone graft covered with pericardium membrane. Clinical and cone beam computed tomography (CBCT) radiographic assessments of the two groups were carried out after a 6-month follow-up period. Results: Clinically, the results showed a significant reduction in furcation involvement (F). The CBCT assessment also revealed reductions in depth (D), height (H), width (W), and 3D radiographic volume of furcation involvement in all study groups at baseline and at 6 months postoperative (p < 0.05) with no significant differences between groups. Conclusions: According to the results of the current study, a two-layer membrane formed by direct loading of bone graft particles onto a pericardium membrane can be used as an effective, reliable, and easy-to-use substitute for direct bone graft application into periodontal defects.


Asunto(s)
Defectos de Furcación , Periodontitis , Humanos , Defectos de Furcación/diagnóstico por imagen , Defectos de Furcación/cirugía , Pericardio/diagnóstico por imagen , Pericardio/cirugía
11.
Sci Rep ; 13(1): 4198, 2023 03 14.
Artículo en Inglés | MEDLINE | ID: mdl-36918622

RESUMEN

Aloe vera has antimicrobial activity and enhances the osseointegration process, thus it may have the potential in treating periodontal defects. This study aimed to evaluate the effect of Aloe vera as an adjunction to Beta-tricalcium phosphate (ß-TCP) bone graft in Grade II furcation defects. A randomized study was conducted on six healthy mongrel dogs' premolars. A total of twenty-four Grade II furcation critical-sized defects were surgically created after reflecting a full-thickness flap, twelve defects were filled with ß-TCP while the other twelve defects were filled with Aloe vera mixed with ß-TCP and both covered by collagen membrane. Animals were euthanized at the end of the fourth and eighth week and defects were analyzed histologically and histomorphometrically. Histologically, Aloe vera mixed with ß-TCP resulted in more bone formation and new PDL fibers compared to ß-TCP alone. After 2 and 4 weeks, the experimental group had significantly higher newly formed interradicular bone height (p < 0.0001, and p < 0.0001, respectively), bone thickness (p < 0.0001, and p < 0.0001, respectively), and percentage of the surface area (p = 0.009, and p = 0.023, respectively). Aloe vera gel adjunctive to ß-TCP is an effective bioactive agent that enhances periodontal tissue regeneration and bone formation in critically sized defects.


Asunto(s)
Aloe , Defectos de Furcación , Animales , Perros , Regeneración Ósea , Defectos de Furcación/tratamiento farmacológico , Defectos de Furcación/cirugía , Fosfatos de Calcio/farmacología , Fosfatos de Calcio/uso terapéutico
12.
Clin Oral Investig ; 27(4): 1541-1546, 2023 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-36781478

RESUMEN

OBJECTIVES: Even if it seems to be an important anatomical parameter for tissue regeneration, few studies in literature evaluate the "mean measure" of root divergence. Most of them are linear measurements, which hardly describe the dental furcation conformation in its entirety. It is left to the subjectivity of the operator deciding whether a furcation is convergent or divergent. The goal of this study is to create a visual evaluation method using specific measurements applied on endo-oral X-rays to overcome these problems, giving a conformation of the entire interradicular space and its divergence. MATERIAL AND METHODS: A user-friendly software (Paint®, Windows10®) was used to take three different measurements on endo-oral radiographs of upper and lower molars. Three blind operators measured 20 radiographs, to analyze the intra- and inter-operator reproducibility of the measurements. Then, the technique was repeated on 250 radiographic images to identify an average value and define a main conformation of the interradicular space. The ratio of these three measurements allowed to develop a new visual evaluation method of the interradicular space. RESULTS: Intra and inter-operator reproducibility was statistically confirmed on a sample of 20 anonymous endo-oral radiographs measured by 3 blind operators, indicating that the measurement technique was not operator dependent. Measurement made on 250 X-rays obtained with this technique permitted to subdivide in five groups the conformation of the interradicular space and define a mean value of the interradicular space. CONCLUSIONS: A new anatomical evaluation of the interradicular space in its entirety, which could help the clinicians in diagnostic and decisional phase in the therapy of furcated molars, can be obtained. CLINICAL RELEVANCE: A pre-operative evaluation of interradicular space conformation could affect therapy treatment choice.


Asunto(s)
Defectos de Furcación , Diente Molar , Humanos , Reproducibilidad de los Resultados , Radiografía , Diente Molar/diagnóstico por imagen , Diagnóstico Bucal , Defectos de Furcación/diagnóstico por imagen , Defectos de Furcación/cirugía
13.
Artículo en Inglés | MEDLINE | ID: mdl-36661872

RESUMEN

The aim of the present study was to evaluate, clinically and via CBCT, the long-term efficacy of a bioresorbable polylactic acid membrane combined with deproteinized bovine bone graft (DBBM) and compare it to enamel matrix derivative (EMD) combined with DBBM graft in the treatment of class II furcation defects. Sites were randomly assigned to the test group (Guidor Matrix Barrier + Bio-Oss) or the control group (Emdogain + Bio-Oss). Probing pocket depth (PPD), clinical attachment level (CAL), gingival recession (REC), and keratinized tissue (KT) width were assessed at 12 and 24 months, and radiographic bone gain was investigated at 24 months via CBCT. Both groups showed a significant radiographic bone fill and clinical gain. The combination of Emdogain + Bio-Oss showed better clinical outcomes and less complications, though this difference was not statistically significant.


Asunto(s)
Pérdida de Hueso Alveolar , Proteínas del Esmalte Dental , Defectos de Furcación , Recesión Gingival , Tomografía Computarizada de Haz Cónico Espiral , Animales , Bovinos , Humanos , Pérdida de Hueso Alveolar/cirugía , Proteínas del Esmalte Dental/uso terapéutico , Estudios de Seguimiento , Defectos de Furcación/diagnóstico por imagen , Defectos de Furcación/cirugía , Recesión Gingival/diagnóstico por imagen , Recesión Gingival/cirugía , Regeneración Tisular Guiada Periodontal/métodos , Pérdida de la Inserción Periodontal/cirugía , Resultado del Tratamiento
14.
Quintessence Int ; 54(2): 112-124, 2023 Feb 10.
Artículo en Inglés | MEDLINE | ID: mdl-36445774

RESUMEN

OBJECTIVES: In preparation of a definitive randomized clinical trial (RCT), the current parallel-grouped triple-blind pilot RCT assessed the efficacy of recombinant human bone morphogenetic protein-2 (rhBMP-2) with polylactic acid/polyglycolic acid (PLA/PGA) membrane for improvement of periodontal tissue regeneration in Class II furcation type defects. METHOD AND MATERIALS: With the present single-center investigation, 24 patients/24 mandibular molars revealing Class II furcation lesions with involved buccal surfaces were randomly allocated and treated surgically, using either a PLA/PGA membrane alone (control, n = 12) or in combination with rhBMP-2 (n = 12). Assessors, participants, and the statistician were blinded to the treatment groups. Clinical parameters including Plaque Index (PI), Papillary Bleeding Index (PBI), clinical attachment level, vertical probing depth, horizontal probing depth, and gingival recession were assessed at baseline and 6 months postsurgery. RESULTS: Baseline values concerning the investigated parameters were comparable between both groups (P > .05). After 6 months, clinical attachment level gain was similar (P = .76), while greater reductions in vertical probing depth (P = .01) and horizontal probing depth (P = .05), along with less gingival recession (P = .03) were observed in the PLA/PGA + rhBMP-2 group (compared to the controls). An increased number of completely closed furcation type defects was observed in the PLA/PGA + rhBMP-2 group (with no adverse effects). CONCLUSIONS: When treating Class II furcation lesions, the use of rhBMP-2 (combined with PLA/PGA membranes) seems advantageous. The presented set-up seems feasible with regards to recruitment, randomization, acceptance, retention, and adherence to the study protocol. (Quintessence Int 2023;54:112-124; doi: 10.3290/j.qi.b3631815).


Asunto(s)
Defectos de Furcación , Recesión Gingival , Humanos , Recesión Gingival/cirugía , Defectos de Furcación/cirugía , Implantes Absorbibles , Proyectos Piloto , Pérdida de la Inserción Periodontal/cirugía , Poliésteres , Diente Molar/cirugía , Regeneración Tisular Guiada Periodontal/métodos , Membranas Artificiales , Resultado del Tratamiento
15.
Quintessence Int ; 54(3): 210-219, 2023 Mar 17.
Artículo en Inglés | MEDLINE | ID: mdl-36472512

RESUMEN

OBJECTIVE: The aim of this systematic review and meta-analysis was to evaluate the clinical efficacy of the use of systemic antibiotics in regenerative periodontal surgery for treating teeth affected by periodontitis. DATA SOURCES: Electronic (MEDLINE, EMBASE, LILACS, Scopus, and Cochrane) and manual literature searches for human randomized controlled trial studies published up to November 2022 were conducted by two reviewers. Meta-analysis was performed to assess probing pocket depth (PPD) reduction and clinical attachment level (CAL) gain in groups receiving systemic antibiotics compared to those not receiving systemic antibiotics. A total of eight studies were included. While treated sites were intrabony defects in six papers, two studies focused on furcation defects. For intrabony defects, the weighted mean difference (WMD) of 0.30 mm (95% CI -0.18 to 0.78) and 0.27 mm (95% CI -0.13 to 0.66) was calculated for PPD reduction and CAL gain, respectively. The differences between antibiotics and non-antibiotics groups for PPD and CAL were not statistically significant. Quantitative analysis could not be performed for furcation defects due to the limited number of studies. However, regardless of the membrane type selection, the existing evidence indicated that antibiotics did not lead to superior clinical outcomes for furcation defects at 9 to 12 months after the regenerative procedures. CONCLUSION: Based on this meta-analysis study's findings, the use of adjunct systemic antibiotics in regenerative periodontal surgery did not appear to achieve more favorable clinical outcomes. Thus, the use of adjunct systemic antibiotics as part of the regenerative periodontal therapy might not be justifiable and should be reconsidered. (Quintessence Int 2023;54:210-219; doi: 10.3290/j.qi.b3648957).


Asunto(s)
Pérdida de Hueso Alveolar , Defectos de Furcación , Periodontitis , Humanos , Defectos de Furcación/tratamiento farmacológico , Defectos de Furcación/cirugía , Ensayos Clínicos Controlados Aleatorios como Asunto , Periodontitis/cirugía , Resultado del Tratamiento , Regeneración , Regeneración Tisular Guiada Periodontal , Pérdida de Hueso Alveolar/cirugía
16.
Oral Dis ; 29(8): 3583-3598, 2023 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-35839150

RESUMEN

BACKGROUND: Periodontal regenerative therapy using bone-substituting materials has gained favorable clinical significance in enhancing osseous regeneration. These materials should be biocompatible, osteogenic, malleable, and biodegradable. This study assessed the periodontal regenerative capacity of a novel biodegradable bioactive hydrogel template of organic-inorganic composite loaded with melatonin. MATERIALS AND METHODS: A melatonin-loaded alginate-chitosan/beta-tricalcium phosphate composite hydrogel was successfully prepared and characterized. Thirty-six critical-sized bilateral class II furcation defects were created in six Mongrel dogs, and were randomly divided and allocated to three cohorts; sham, unloaded composite, and melatonin-loaded. Periodontal regenerative capacity was evaluated via histologic and histomorphometric analysis. RESULTS: Melatonin-treated group showed accelerated bone formation and advanced maturity, with a significant twofold increase in newly formed inter-radicular bone compared with the unloaded composite. The short-term regenerative efficacy was evident 4 weeks postoperatively as a significant increase in cementum length concurrent with reduction of entrapped epithelium. After 8 weeks, the scaffold produced a quality of newly synthesized bone similar to normal compact bone, with potent periodontal ligament attachment. CONCLUSIONS: Melatonin-loaded hydrogel template accelerated formation and enhanced quality of newly formed bone, allowing complete periodontal regeneration. Furthermore, the scaffold prevented overgrowth and entrapment of epithelial cells in furcation defects.


Asunto(s)
Defectos de Furcación , Melatonina , Animales , Perros , Regeneración Ósea , Cemento Dental , Defectos de Furcación/tratamiento farmacológico , Defectos de Furcación/cirugía , Defectos de Furcación/patología , Regeneración Tisular Guiada Periodontal , Hidrogeles , Melatonina/farmacología , Melatonina/uso terapéutico , Ligamento Periodontal/patología
17.
J Nepal Health Res Counc ; 20(2): 510-516, 2022 Nov 03.
Artículo en Inglés | MEDLINE | ID: mdl-36550737

RESUMEN

BACKGROUND: The management of furcation involvements by regenerative surgery with bone alloplast have been used with varying degrees of success in periodontal therapy. The aim of the study was to clinically and radiographically compare the effectiveness of Hydroxyapatite bone alloplast with combination bone alloplast (Hydroxyapatite and ?-Tricalcium phosphate) for the treatment of Grade II mandibular furcation involvements. METHODS: Thirty patients with bilateral Grade II mandibular furcation involvements were distributed in Group A (Hydroxyapatite) and Group B (Hydroxyapatite and ?-Tricalcium phosphate). Clinical parameters such as Plaque Index, Gingival Index, Probing Pocket Depth, Clinical Attachment Level and Horizontal Probing Depth were recorded at baseline and at one, three and six mths postoperatively. Radiographic bone fill measurements were recorded at baseline and six months post-operatively. RESULTS: Both the groups showed statistically significant (p <0.01) improvement in clinical and radiographic parameters at each recall visits. Inter-group comparison of clinical parameters showed no significant difference in both the groups whereas radiographic measurements following six months post-surgery showed significantly (p <0.05) greater amount of bone fill in Group B compared to Group A. CONCLUSIONS: It can be concluded that at six months post-operative, both the alloplastic materials resulted in significant improvement in clinical parameters and no significant difference was found between both groups. There was a statistically significant radiographic bone fill when a combination of Hydroxyapatite and ?-Tricalcium phosphate was used demontrating its effectiveness in the treatment of Grade II Furcation involvement.


Asunto(s)
Durapatita , Defectos de Furcación , Humanos , Durapatita/uso terapéutico , Resultado del Tratamiento , Defectos de Furcación/tratamiento farmacológico , Defectos de Furcación/cirugía , Nepal
18.
Quintessence Int ; 53(10): 884-891, 2022 Oct 21.
Artículo en Inglés | MEDLINE | ID: mdl-36268948

RESUMEN

The outcome in the treatment of furcation defects is often unsatisfactory. The reasons are morphologic and pathologic peculiarities as well as extensive changes in shape caused by resective treatment of periodontal lesions in multi-rooted teeth. Therefore, augmentative strategies are suggested to improve the prognosis. However, the success rate decreases with increasing severity of the disease. In contrast, if the affected roots are not extracted but are extruded after hemi- or trisection, this leads to a coronal displacement of the disease process and a significantly improved situation for hygiene. At the same time, the resection of inflammatory tissue of the periodontal pockets is accompanied by vertical and horizontal bone apposition. The results are predictable and stable in the long term. The burden for the patient is low. ((Quintessence Int 2022;53: 884-891; Originally published (in German) in Quintessenz Zahnmedizin 2020; 71(9): 1024-1032; doi: 10.3290/j.qi.b3418205).


Asunto(s)
Defectos de Furcación , Humanos , Defectos de Furcación/cirugía , Raíz del Diente/cirugía , Bolsa Periodontal/cirugía , Regeneración Tisular Guiada Periodontal/métodos
19.
Dentomaxillofac Radiol ; 51(8): 20210529, 2022 Dec 01.
Artículo en Inglés | MEDLINE | ID: mdl-35787071

RESUMEN

OBJECTIVE: Multirooted teeth respond less favorably to non-surgical periodontal treatment and long-term tooth prognosis is influenced by the degree of furcation involvement (FI). Therapeutic strategy for multirooted teeth is essentially based on accurate diagnosis of the FI. The aim of this systematic review is to evaluate the accuracy of the different furcation assessment methods and to determine if radiographic help is needed to determine early stage of FI. METHODS: Electronic databases were searched up to March 2021. Comparative studies describing the reliability of different clinical and/or radiological furcation assessment methods were identified. RESULTS: A total of 22 studies comparing at least 2 furcation assessment methods, among which 15 retrospective studies, 5 prospective studies, 1 randomized controlled trial and 1 case series, were included in this review. The reliability of cone beam CT (CBCT), intraoral radiographs (IOs), orthopantomograms (OPGs) and MRI to identify FI was evaluated. Using OFS as a reference for FI detection and diagnosis, agreement ranged from 43.3 to 63% for OPG, 38.7 to 83.1% for IO and 82.4 to 84% for CBCT. The validity of the measurements was mainly influenced by the location of the furcation entrance. For radiological diagnosis, CBCT displayed the closest agreement with OFS while the accuracy of IO and OPG showed modest agreement and were influenced by the examiner's experience. CONCLUSION: Altogether, it appears that the use of IO, OPG or CBCT allows detection of FI but could not be considered as gold-standard techniques.


Asunto(s)
Defectos de Furcación , Humanos , Defectos de Furcación/diagnóstico por imagen , Defectos de Furcación/cirugía , Diente Molar , Estudios Retrospectivos , Reproducibilidad de los Resultados , Estudios Prospectivos , Tomografía Computarizada de Haz Cónico , Ensayos Clínicos Controlados Aleatorios como Asunto
20.
Bull Tokyo Dent Coll ; 63(2): 85-94, 2022 Jun 15.
Artículo en Inglés | MEDLINE | ID: mdl-35613865

RESUMEN

This report describes a case of generalized chronic periodontitis requiring periodontal treatment including surgery. The patient was a 64-year-old man who visited the Tokyo Dental College Suidobashi Hospital with the chief complaint of pain in tooth #27. An initial examination revealed a probing depth (PD) of ≥4 mm at 38.2% of sites and bleeding on probing at 26.5% of sites. Radiographic examination revealed vertical bone resorption in # 27, 34, and 47, and horizontal resorption in other areas. Based on a clinical diagnosis of severe chronic periodontitis, initial periodontal therapy consisting of plaque control, scaling and root planing was performed. Both #27 and #47 were extracted due to bone resorption extending as far as the root apex. After initial periodontal therapy, sites with a PD of ≥4 mm were observed at 16.7% of sites. Furcation involvement was observed in #16, 17, 36, and 37. The need and options for periodontal surgery based on these findings were explained to the patient. Open flap debridement was implemented for #16, 17, 31, 34, 36, and 37 to reduce periodontal pockets. After reevaluation, the patient was placed on supportive periodontal therapy. The results of the periodontal examination at first visit revealed a periodontal pocket depth of 6 mm and 7 mm in #16 and 17, respectively, and class II furcation involvement in both. Periodontal therapy with open flap debridement resulted in an improvement in horizontal bone resorption where there was class II furcation involvement. This improvement has been adequately maintained over a 4-year period.


Asunto(s)
Pérdida de Hueso Alveolar , Periodontitis Crónica , Defectos de Furcación , Pérdida de Hueso Alveolar/diagnóstico por imagen , Pérdida de Hueso Alveolar/cirugía , Periodontitis Crónica/diagnóstico por imagen , Periodontitis Crónica/cirugía , Estudios de Seguimiento , Defectos de Furcación/diagnóstico por imagen , Defectos de Furcación/cirugía , Humanos , Masculino , Persona de Mediana Edad , Pérdida de la Inserción Periodontal , Bolsa Periodontal/cirugía , Aplanamiento de la Raíz , Resultado del Tratamiento
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