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1.
Clin Nutr ; 40(11): 5500-5510, 2021 11.
Artículo en Inglés | MEDLINE | ID: mdl-34656032

RESUMEN

BACKGROUND: Many older hospitalized patients are at nutritional risk or malnourished and the nutritional condition is often further impaired during hospitalization. When discharged to own home, a "Nutrition Gap" often occurs, causing inadequate dietary intake, and potentially impeded recovery. Previously, cross-sectorial studies of single component nutritional intervention have shown a limited effect on clinically relevant outcomes. We hypothesized that a multimodal nutritional intervention is necessary to elicit a beneficial effect on clinically relevant outcomes. METHODS: A randomized controlled trial was performed for a period of 16 weeks. At discharge, the intervention group (IG) received dietetic counselling including a recommendation of daily training, an individual nutrition plan and a package containing foods and drinks covering dietary requirements for the next 24 h. Further, a goodie-bag containing samples of protein-rich milk-based drinks were provided. Information regarding recommendations of nutritional therapy after discharge was systematically and electronically communicated to the municipality. The dietician performed telephone follow-ups on day 4 and 30 and a home visit at 16 weeks. The control group (CG) received standard treatment. The primary outcome was readmissions within 6 month, secondary outcomes were Length of Stay (LOS), Health Related Quality of Life (EQ-5D-3L), nutritional status, physical function (30s-CST) and mortality. This trial was registered under ClinicalTrials.gov Identifier no. NCT03488329. RESULTS: We included 191 patients (IG: n = 93). No significant difference was seen in readmissions within 6 month (IG: 45% vs. CG: 45%, Risk Ratio (RR): 0.96 0.71-1.31, p = 0.885). At the 16-weeks follow-up more patients in the IG reached at least 75% of energy and protein requirements (82% vs. CG: 61%, p = 0,007). The energy (kcal) and protein intake (g) per kg was significantly higher in the IG (26.4 kcal/kg (±7.4) vs. 22.6 (±7.4), p = 0.0248) (1.1 g/kg (±0.3) vs. 0.9 g/kg (±0.3). Furthermore, significant lower weight loss was seen in IG (0.7 (±4.3) vs. -1.4 (±3.6), p = 0.002). A significant and clinically relevant difference was found in the EQ-5D-3L VAS-score (IG: mean 61.6 ± 16.2 vs. CG: 53.3 ± 19.3, p = 0.011) (Δ14.3 (±15.5) vs. Δ5.6 (±17.2), p = 0.002). A significant difference in mean 30s-CST in IG was also found (7.2 (±4.3) vs. 5.3 (±4.1), p = 0.010). The improvements in physical function were of clinical relevance in both groups, but significantly higher in the IG (Δ4.2 (±4.4) vs. Δ2.2 (±2.5), p = 0.008). In fact, 86% in IG experienced improvements in the 30s-CST compared with 68% in the CG (p = 0.022). LOS was found to be lower at all time points, however not significant (30 days: -3 (-8.5 to 2.5), p = 0.276, 16 weeks: -4 (-10.2 to 2.2, p = 0.204), 6 months: -3 (-9.3 to 3.3, p = 0346)). All-cause mortality was not different between groups, however RR showed a non-significantly 47% reduction at day 30 (0.53 (0.14-2.05, p = 0.499)) and a 17% reduction at 16 weeks (0.83 (0.40-1.73, p = 1.000)) in IG. Per protocol (PP) analysis revealed a non-significant decrease of 32% in readmission at 6 months (RR: 0.68 (0.42-1.08), p = 0.105). CONCLUSION: The present study, using a multimodal nutritional approach, revealed no significant effect on readmissions however a significant positive effect on nutritional status, quality of life and physical function was found. The improvements in quality of life and physical function were of clinical relevance. No significant effect was found on LOS and mortality.


Asunto(s)
Consejo/métodos , Desnutrición/rehabilitación , Terapia Nutricional/métodos , Calidad de Vida , Atención Subaguda/métodos , Anciano , Femenino , Estado Funcional , Evaluación Geriátrica , Humanos , Tiempo de Internación/estadística & datos numéricos , Masculino , Estado Nutricional , Alta del Paciente , Readmisión del Paciente/estadística & datos numéricos , Método Simple Ciego , Resultado del Tratamiento , Pérdida de Peso
2.
Mech Ageing Dev ; 197: 111500, 2021 07.
Artículo en Inglés | MEDLINE | ID: mdl-34010632

RESUMEN

Malnutrition is associated with poor functional performance in geriatric rehabilitation inpatients. However, it is unclear if malnourished patients have poor functional trajectories over time. This study aimed to determine the association between (the risk of) malnutrition at admission and trajectories of Activities of Daily Living (ADL) and Instrumental ADL (IADL) from pre-admission to post-discharge in geriatric rehabilitation inpatients. An observational, longitudinal study was conducted in the REStORing health of acutely unwell adulTs (RESORT) cohort of geriatric rehabilitation inpatients. A total of 618 patients (mean age 82.1 ± 7.8 years, 57.4 % females) were included. The prevalence of the risk of malnutrition, by Malnutrition Screening Tool (MST) was 41.3 % (n = 255) and malnutrition by the Global Leadership Initiative on Malnutrition (GLIM) and European Society for Clinical Nutrition and Metabolism (ESPEN) criteria were 53.5 % (n = 331) and 13.1 % (n = 81) respectively. Malnutrition by the GLIM criteria but not the ESPEN criteria nor the risk of malnutrition, was associated with ADL trajectories of 'remained poor' (OR: 3.33, 95 %CI: 1.21-9.19) and 'deteriorated' (OR: 1.68, 95 %CI: 1.13-2.52) compared to the 'recovered' trajectory. The risk of malnutrition and malnutrition were not associated with IADL trajectories. Malnutrition at admission was associated with poor ADL trajectories but not IADL trajectories in geriatric rehabilitation inpatients.


Asunto(s)
Actividades Cotidianas , Hospitalización , Desnutrición , Anciano , Anciano de 80 o más Años , Femenino , Evaluación Geriátrica , Humanos , Estudios Longitudinales , Masculino , Desnutrición/fisiopatología , Desnutrición/rehabilitación
3.
Nutrients ; 13(2)2021 Jan 26.
Artículo en Inglés | MEDLINE | ID: mdl-33530364

RESUMEN

Malnutrition has a negative impact on patients with chronic pulmonary obstructive disease (COPD). The purpose of this study was to assess the prevalence of malnutrition, defined by the Global Leadership Initiative for Malnutrition (GLIM), in stable COPD patients referred to pulmonary rehabilitation, and to explore potential associations of malnutrition according to GLIM, and its components, with increased risk of mortality and hospitalizations in 2 years. In a post-hoc analysis of a prospective cohort of 200 rehabilitation patients with stable COPD, main outcome variables were hospital admissions, length of stay, and mortality during a 2-year follow-up. Covariates were malnutrition according to GLIM and its phenotypic criteria: unintentional weight loss, low body mass index (BMI), and low fat-free mass (FFM). Univariate and multivariate analysis were performed using logistic and proportional hazard Cox regression. Malnutrition according to GLIM showed 45% prevalence and was associated with increased mortality risk. Low age-related BMI and FFM were independently associated with mortality, which persisted after adjustment for age and lung function. Malnutrition and low BMI were also associated with increased risk of hospitalization. Malnutrition according to GLIM criteria was highly prevalent in rehabilitation patients with COPD and was associated with nearly 3 times greater mortality and hospitalization risk.


Asunto(s)
Hospitalización , Desnutrición/mortalidad , Desnutrición/rehabilitación , Enfermedad Pulmonar Obstructiva Crónica/complicaciones , Anciano , Índice de Masa Corporal , Femenino , Humanos , Liderazgo , Masculino , Persona de Mediana Edad , Análisis Multivariante , Prevalencia , Estudios Prospectivos , Pérdida de Peso
4.
Int J Rehabil Res ; 44(1): 57-64, 2021 Mar 01.
Artículo en Inglés | MEDLINE | ID: mdl-32909990

RESUMEN

Patients with Guillain-Barré syndrome (GBS) are at high risk for inadequate nutrition throughout their illness, yet the wider impact of malnutrition in this population remains unknown. Thus, the purpose of our study was to investigate the associations between nutritional status and functional status at admission to inpatient rehabilitation for GBS and to determine whether the admission phase angle, a biological marker of cellular health, is a prognostic indicator of functional improvement at the end of rehabilitation. The study included 27 participants recovering from GBS who screened positive for nutritional risk upon admission to rehabilitation. According to the Global Leadership Initiative on Malnutrition criteria, the majority of participants were classified as malnourished. A decreased phase angle was found in 93% (mean 3.7°, SD 1.3°). Lower phase angle was moderately associated with lower motor Functional Independence Measure (mFIM) at admission (r = 0.53, P = 0.005), suggesting that phase angle may be an indicator of functional status. By the end of rehabilitation, all participants improved functional independence and muscle strength, and the majority improved walking abilities. However, the correlation between admission phase angle and mFIM efficiency was not statistically significant (P = 0.3867). We conclude that malnutrition is significantly associated with low functional independence and muscle strength at admission. The inability of admission phase angle to predict functional improvement is probably due to the complex interactions between recovery from GBS and interventions provided during a comprehensive multidisciplinary rehabilitation for GBS, and also relatively small sample size.


Asunto(s)
Composición Corporal/fisiología , Impedancia Eléctrica , Síndrome de Guillain-Barré/fisiopatología , Síndrome de Guillain-Barré/rehabilitación , Desnutrición/fisiopatología , Adulto , Anciano , Índice de Masa Corporal , Evaluación de la Discapacidad , Femenino , Estado Funcional , Humanos , Masculino , Desnutrición/rehabilitación , Persona de Mediana Edad , Fuerza Muscular/fisiología , Estado Nutricional , Estudios Retrospectivos , Adulto Joven
5.
Nutrients ; 12(7)2020 Jun 29.
Artículo en Inglés | MEDLINE | ID: mdl-32610491

RESUMEN

Previous studies have suggested that the nutritional status after stroke is independently associated with long-term outcomes and that sarcopenia delays poststroke rehabilitation and worsens the prognosis. However, many stroke patients have a deteriorated nutritional status and a decreased muscle mass in the acute phase. This prospective study included 179 patients who were admitted to the stroke rehabilitation unit. We performed bioelectrical impedance analysis and determined the Geriatric Nutritional Risk Index (GNRI) to assess muscle mass and the nutritional status on admission. Furthermore, we analyzed the activities of daily living using the Functional Independence Measure (FIM) at the time of admission and four weeks later. Furthermore, we evaluated the change in motor FIM items and examined the relationship with the data. Multiple regression analysis revealed that a high muscle rate (skeletal muscle mass/body weight) (odds ratio OR = 2.43), high phase angle (OR = 3.32), and high GNRI (OR = 2.57) were significantly associated with motor FIM items at four weeks in male and female patients. Muscle mass maintenance through nutritional management and early rehabilitation in the acute period of stroke is essential for functional recovery in stroke patients.


Asunto(s)
Composición Corporal , Estado Nutricional , Recuperación de la Función/fisiología , Rehabilitación de Accidente Cerebrovascular/estadística & datos numéricos , Accidente Cerebrovascular/fisiopatología , Actividades Cotidianas , Anciano , Anciano de 80 o más Años , Impedancia Eléctrica , Femenino , Evaluación Geriátrica , Hospitalización/estadística & datos numéricos , Humanos , Masculino , Desnutrición/etiología , Desnutrición/rehabilitación , Evaluación Nutricional , Rendimiento Físico Funcional , Estudios Prospectivos , Sarcopenia/etiología , Sarcopenia/rehabilitación , Accidente Cerebrovascular/complicaciones , Resultado del Tratamiento
6.
Clin Nutr ; 39(8): 2557-2563, 2020 08.
Artículo en Inglés | MEDLINE | ID: mdl-31796229

RESUMEN

BACKGROUND & AIMS: Malnutrition, frailty, physical frailty, and disability are common conditions in patients with chronic obstructive pulmonary disease (COPD). Insight in the coexistence and relations between these conditions may provide information on the nature of the relationship between malnutrition and frailty. Such information may help to identify required interventions to improve the patient's health status. We therefore aimed to explore whether malnutrition, frailty, physical frailty, and disability coexist in patients with COPD at the start of pulmonary rehabilitation. METHODS: For this cross-sectional study, from March 2015 to May 2017, patients with COPD were assessed at the start of a pulmonary rehabilitation program. Nutritional status was assessed with the Scored Patient-Generated Subjective Global Assessment (PG-SGA) based Pt-Global app. Frailty was assessed by the Evaluative Frailty Index for Physical activity (EFIP), physical frailty by Fried's criteria, and disability by the Dutch version of World Health Organization Disability Assessment Schedule 2.0 (WHODAS). These variables were dichotomized to determine coexistence of malnutrition, frailty, physical frailty, and disability. Associations between PG-SGA score and respectively EFIP score, Fried's criteria, and WHODAS score were analyzed by Pearson's correlation coefficient. Two tailed P-values were used, and significance was set at P < 0.05. RESULTS: Of the 57 participants included (age 61.2 ± 8.7 years), malnutrition and frailty coexisted in 40%. Malnutrition and physical frailty coexisted in 18%, and malnutrition and disability in 21%. EFIP score and PG-SGA score were significantly correlated (r = 0.43, P = 0.001), as well as Fried's criteria and PG-SGA score (r = 0.37, P = 0.005). CONCLUSIONS: In this population, malnutrition substantially (40%) coexists with frailty. Although the prevalence of each of the four conditions is quite high, the coexistence of all four conditions is limited (11%). The results of our study indicate that nutritional interventions should be delivered by health care professionals across multiple disciplines.


Asunto(s)
Personas con Discapacidad/estadística & datos numéricos , Fragilidad/epidemiología , Desnutrición/epidemiología , Medicina Física y Rehabilitación/estadística & datos numéricos , Enfermedad Pulmonar Obstructiva Crónica/epidemiología , Anciano , Comorbilidad , Estudios Transversales , Evaluación de la Discapacidad , Personas con Discapacidad/rehabilitación , Femenino , Anciano Frágil/estadística & datos numéricos , Fragilidad/rehabilitación , Evaluación Geriátrica , Indicadores de Salud , Humanos , Masculino , Desnutrición/rehabilitación , Persona de Mediana Edad , Evaluación Nutricional , Estado Nutricional , Prevalencia , Enfermedad Pulmonar Obstructiva Crónica/rehabilitación
7.
Nutrition ; 71: 110613, 2020 03.
Artículo en Inglés | MEDLINE | ID: mdl-31837639

RESUMEN

OBJECTIVE: The aim of this study was to examine the effect of improved nutritional status on activities of daily living (ADLs) and dysphagia in elderly patients with pneumonia who were admitted to acute care hospitals. METHODS: A retrospective cohort study was conducted using registry data from the Japan Rehabilitation Nutrition Database of patients with pneumonia who were admitted to acute care hospitals. Patients were divided into two groups based on the Mini Nutritional Assessment Short-Form (MNA-SF) status at discharge: Patients with no status change or with decreased status were allocated to the unimproved nutritional status (UN) group and those with increased status were assigned to the improved nutritional status (IN) group. The primary outcome was ADLs as assessed by Barthel Index (BI) score at hospital discharge. Secondary outcomes included dysphagia as assessed by the Food Intake Level Scale (FILS) at discharge. RESULTS: The study included 143 patients with a mean age of 84.7 ± 7.8 y. Based on the MNA-SF categories at discharge, 127 (88.8%) patients were assigned to the UN group and 16 (11.2%) to the IN group. Patients in the IN group had significantly higher BI and FILS scores than those in the UN group. Multiple regression analysis indicated that improvement in nutritional status was independently associated with BI gain (B = 9.916; ß = 0.153; 95% confidence interval [CI], 1.929-11.761; P = 0.017) and FILS gain (B = 1.259; ß = 0.167; 95% CI, 1.224-2.814; P = 0.044). CONCLUSIONS: Nutritional improvement is associated with improvements in ADL and dysphagia in patients with pneumonia and malnutrition.


Asunto(s)
Actividades Cotidianas , Estado Nutricional , Admisión del Paciente/estadística & datos numéricos , Alta del Paciente/estadística & datos numéricos , Neumonía/fisiopatología , Anciano de 80 o más Años , Bases de Datos Factuales , Trastornos de Deglución/complicaciones , Trastornos de Deglución/fisiopatología , Trastornos de Deglución/rehabilitación , Femenino , Evaluación Geriátrica , Hospitales , Humanos , Japón , Masculino , Desnutrición/complicaciones , Desnutrición/fisiopatología , Desnutrición/rehabilitación , Evaluación Nutricional , Neumonía/complicaciones , Neumonía/rehabilitación , Análisis de Regresión , Estudios Retrospectivos , Resultado del Tratamiento
8.
Nutrients ; 11(12)2019 Dec 04.
Artículo en Inglés | MEDLINE | ID: mdl-31817074

RESUMEN

BACKGROUND: Crohn's disease (CD) is a chronic inflammatory bowel disease frequently associated with malabsorption and secondary protein-energy malnutrition (PEM). METHODS: Biochemical and clinical data of 63 (34 females, 29 males) patients with PEM due to CD sent to our outpatient unit for nutritional evaluation were retrospectively analyzed. Patients were divided into two groups, according to disease activity. Thirty-eight patients (group A) had the active disease, and 25 patients (group B) suffered from malabsorption resulting from past intestinal resections due to CD. After a physical and hemato-biochemical evaluation at the first visit, all patients received disease-specific personalized dietetic indications. When indicated, oral nutritional supplements, oral/parenteral vitamins, micronutrients, and electrolytes, up to parenteral nutrition, were prescribed. RESULTS: After 1, 3, and 6 months of nutritional therapy, body weight, body mass index (BMI), and serum butyryl-cholinesterase significantly improved in both groups. In 8 out of 13 (61.5%) patients with a cutaneous stoma, intestinal continuity was restored. CONCLUSIONS: This study confirms the effectiveness of nutritional rehabilitation and provides information on the time required for nutritional treatment in patients with CD, both during the acute phase and after malabsorption due to intestinal resection.


Asunto(s)
Enfermedad de Crohn , Desnutrición , Adolescente , Adulto , Anciano , Peso Corporal/fisiología , Enfermedad de Crohn/complicaciones , Enfermedad de Crohn/dietoterapia , Enfermedad de Crohn/rehabilitación , Femenino , Humanos , Masculino , Desnutrición/dietoterapia , Desnutrición/etiología , Desnutrición/rehabilitación , Persona de Mediana Edad , Apoyo Nutricional , Estudios Retrospectivos , Adulto Joven
10.
Nutrients ; 11(9)2019 Sep 06.
Artículo en Inglés | MEDLINE | ID: mdl-31500109

RESUMEN

BACKGROUND: Lack of evidence on the burden and risk factors for malnutrition among children with cerebral palsy (CP) in Vietnam limits evidence-based interventions. We aimed to define the nutritional status of children with CP in Vietnam. MATERIALS AND METHODS: The study utilized data from active prospective hospital-based surveillance modelled on the Pediatric Active Enhanced Disease Surveillance system. Children (0-18 years) with CP attending the National Children's Hospital Hanoi, Vietnam between June-November 2017 were included. Data on demographic, clinical and rehabilitation status were collected following detailed neurodevelopmental assessment. Anthropometric measurements were taken. Nutritional status was determined using the World Health Organization guideline. RESULTS: Of 765 children (the mean (SD) age was 2.6 (2.5) years; 35.8% were female), 28.9% (n = 213) were underweight and 29.0% (n = 214) stunted. The odds of underweight were significantly higher among children aged >5 years and/or having a monthly family income of <50 USD. Underweight and/or stunting was high among children with quadriplegia (81%, n = 60 and 84.5%, n = 87) and/or Gross Motor Functional Classification System (GMFCS) level IV-V (62.5%, n = 45 and 67.0%, n = 67). Nearly one-third of intellectually impaired and more than half of hearing-impaired children were underweight and/or stunted. CONCLUSIONS: Poor economic status and increased motor severity increased vulnerability to malnutrition. Our findings will inform nutritional rehabilitation programs among these vulnerable children.


Asunto(s)
Parálisis Cerebral/epidemiología , Trastornos de la Nutrición del Niño/epidemiología , Fenómenos Fisiológicos Nutricionales Infantiles , Niños con Discapacidad , Trastornos de la Nutrición del Lactante/epidemiología , Desnutrición/epidemiología , Estado Nutricional , Adolescente , Desarrollo del Adolescente , Fenómenos Fisiológicos Nutricionales de los Adolescentes , Factores de Edad , Parálisis Cerebral/fisiopatología , Parálisis Cerebral/psicología , Parálisis Cerebral/rehabilitación , Niño , Desarrollo Infantil , Trastornos de la Nutrición del Niño/fisiopatología , Trastornos de la Nutrición del Niño/rehabilitación , Preescolar , Femenino , Trastornos del Crecimiento/epidemiología , Trastornos del Crecimiento/fisiopatología , Humanos , Lactante , Trastornos de la Nutrición del Lactante/fisiopatología , Trastornos de la Nutrición del Lactante/rehabilitación , Fenómenos Fisiológicos Nutricionales del Lactante , Recién Nacido , Masculino , Desnutrición/fisiopatología , Desnutrición/rehabilitación , Actividad Motora , Encuestas Nutricionales , Estudios Prospectivos , Delgadez/epidemiología , Delgadez/fisiopatología , Vietnam/epidemiología
12.
Gut Liver ; 13(5): 576-581, 2019 09 15.
Artículo en Inglés | MEDLINE | ID: mdl-30970437

RESUMEN

Background/Aims: Refeeding syndrome (RFS) is a fatal clinical complication that can occur as a result of fluid and electrolyte shifts during early nutritional rehabilitation for malnourished patients. This study was conducted to determine the clinical implications of RFS in patients with acute pancreatitis (AP). Methods: Between 2006 and 2016, AP patients with very early mortality were retrospectively enrolled from three university hospitals. Results: Among 3,206 patients with AP, 44 patients died within 3 days after diagnosis. The median age was 52.5 years (range, 27 to 92 years), male-to-female ratio was 3:1, and median duration from admission to death was 33 hours (range, 5 to 72 hours). The etiology of AP was alcohol abuse in 32 patients, gallstones in five patients, and hypertriglyceridemia in two patients. Ranson score, bedside index for severity of AP, and acute physiology and chronic health evaluation-II were valuable for predicting very early mortality (median, [range]; 5 [1 to 8], 3 [0 to 5], and 19 [4 to 45]). RFS was diagnosed in nine patients who died of septic shock (n=5), cardiogenic shock (n=2), or cardiac arrhythmia (n=2). In addition, patients with RFS had significant hypophosphatemia compared to non-RFS patients (2.6 mg/dL [1.3 to 5.1] vs 5.8 mg/dL [0.8 to 15.5]; p=0.001). The early AP-related mortality rate within 3 days was approximately 1.4%, and RFS occurred in 20.5% of these patients following sudden nutritional support. Conclusions: The findings of current study emphasize that clinicians should be aware of the possibility of RFS in malnourished AP patients with electrolyte imbalances.


Asunto(s)
Pancreatitis/mortalidad , Síndrome de Realimentación/mortalidad , Enfermedad Aguda , Adulto , Anciano , Anciano de 80 o más Años , Hospitalización , Hospitales de Enseñanza , Humanos , Masculino , Desnutrición/mortalidad , Desnutrición/rehabilitación , Persona de Mediana Edad , Apoyo Nutricional/efectos adversos , Pancreatitis/etiología , República de Corea/epidemiología , Estudios Retrospectivos
14.
J Acad Nutr Diet ; 118(7): 1270-1276, 2018 07.
Artículo en Inglés | MEDLINE | ID: mdl-29752190

RESUMEN

BACKGROUND: Several studies have suggested that malnutrition impedes functional recovery in patients with hip fracture, but there are few reports on improvement in nutritional status and return to activities of daily living (ADL) in these patients. OBJECTIVE: This study was conducted to evaluate the relationship between change in nutritional status and recovery of ADL in malnourished patients after hip fracture and to identify predictors of functional recovery among the characteristic features of undernutrition. DESIGN: This was a retrospective observational cohort study. PARTICIPANTS/SETTING: Data for patients aged ≥65 years with hip fracture and malnutrition (Mini Nutritional Assessment-Short Form [MNA-SF] score ≤7) at the time of admission to convalescent rehabilitation units were obtained from the Japan Rehabilitation Nutrition Database between November 2015 and August 2017. MAIN OUTCOME MEASURES: The main outcome measures were Functional Independence Measure (FIM) at discharge and the proportion of patients discharged home. STATISTICAL ANALYSES PERFORMED: Patients were divided into two groups based on MNA-SF scores at discharge: improvement in nutritional status (>7, IN group) and non-improvement in nutritional status (≤7, NN group). Clinical characteristics and outcomes were compared between the groups. Multivariable regression analysis was performed to adjust for confounders including age, sex, comorbidity, pre-fracture ADL level, and FIM score on admission. RESULTS: Of 876 patients, 110 met the eligibility criteria (mean age, 85 years; 78.2% female); 77 of the patients were assigned to the IN group and 33 to the NN group. The patients in the IN group were younger and had higher FIM and MNA-SF scores on admission than those in the NN group. At discharge, the median FIM score was significantly higher in the IN group than in the NN group (110 vs 83, P<0.001). Multivariable analysis revealed a significant association between improvement in nutritional status and higher FIM score at discharge (B=7.377 [B=partial regression coefficient], P=0.036) but no association with discharge to home. Mobility, neuropsychological impairment, and weight loss subscores of MNA-SF were independently associated with discharge FIM score (R2=0.659). CONCLUSIONS: In older patients with hip fracture and malnutrition, improvement in nutritional status was independently associated with improved performance of ADL during inpatient rehabilitation. Weight loss may be an important nutritional indicator for these patients.


Asunto(s)
Actividades Cotidianas , Fracturas de Cadera/rehabilitación , Desnutrición/rehabilitación , Estado Nutricional/fisiología , Recuperación de la Función/fisiología , Anciano , Anciano de 80 o más Años , Bases de Datos Factuales , Femenino , Evaluación Geriátrica , Fracturas de Cadera/complicaciones , Humanos , Pacientes Internos , Japón , Masculino , Desnutrición/complicaciones , Evaluación Nutricional , Rendimiento Físico Funcional , Estudios Retrospectivos , Pérdida de Peso
15.
Asia Pac J Clin Nutr ; 27(3): 728-734, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-29737823

RESUMEN

BACKGROUND AND OBJECTIVES: Severe infection, inadequate food intake, and pressure ulcers in patients with type 2 diabetes can result in malnutrition. We describe a case in which rehabilitation nutrition was effective for treat-ing a pressure ulcer in a malnourished patient with type 2 diabetes. METHODS AND RESULTS: A 58-year-old man with type 2 diabetes was diagnosed with hidradenitis suppurativa on the left buttock and thigh and a severe pres-sure ulcer on his left kneecap. Malnutrition was related to hypermetabolism caused by chronic hidradenitis suppu-rativa and inadequate protein-energy intake before admission. We initiated a rehabilitation nutrition intervention to improve physical function and to treat a pressure ulcer by prescribing 2,000 kcal/day of food, including 80 g of protein, and physical rehabilitation for 40 minutes/day. The patient showed good progress in terms of his physical function and healing of the pressure ulcer. After prescribing 2,250 kcal/day of food, including 85 g of protein, and physical rehabilitation for 60 minutes/day, HbA1c levels increased to 7.4%. The energy prescription was de-creased to 2,000 kcal/day to improve glycemic levels. Then, the patient's weight decreased and his hand grip strength became weaker. On day 134 and discharge the patient could walk independently with a t-cane and ankle supporter. By day 14 after discharge, the pressure ulcer had epithelialized. CONCLUSION: Rehabilitation nutrition management improved physical function and facilitated pressure ulcer healing in a malnourished patient with type 2 diabetes. Close conjoint management of hyperglycemia was also necessary.


Asunto(s)
Diabetes Mellitus Tipo 2/complicaciones , Terapia Nutricional , Úlcera por Presión/dietoterapia , Úlcera por Presión/rehabilitación , Peso Corporal , Ingestión de Energía , Humanos , Masculino , Desnutrición/complicaciones , Desnutrición/dietoterapia , Desnutrición/rehabilitación , Persona de Mediana Edad , Estado Nutricional , Cicatrización de Heridas
16.
Ann Oncol ; 29(suppl_2): ii27-ii34, 2018 02 01.
Artículo en Inglés | MEDLINE | ID: mdl-29741571

RESUMEN

Patients with advanced cancer are at high risk of losing vital body resources resulting in malnutrition, immunodeficiency, impaired quality of life and worse clinical outcome. Prominent among the diverse factors contributing to this complex condition are metabolic derangements characterized by systemic inflammation, catabolism and accumulating changes in body composition. Because cure in advanced cancer still remains elusive, optimal supportive and integrated palliative care are required to allow patients to tolerate aggressive or long-term anticancer treatments, to maintain an adequate quality of life or to stay the course of advancing disease. Support needs to address and focus on all physical, psychological and social problems interfering with food intake, digestion and anabolism to maintaining adequate body resources and functions. Reliable screening for malnutrition, adequate assessment of the nutritional and metabolic status, and individualized multimodal care require the establishment of dedicated operating procedures involving experts and standardized pathways for communication among all participants involved in clinical cancer care. Therapeutic options include counseling, enriching foods, oral nutritional supplements, enteral and parenteral nutrition, metabolic modulation, exercise training, supportive care to enable and improve the intake of adequate amounts of food, as well as psycho-oncology and social support. Finally, to enable this new level of nutritional and metabolic patient care it appears necessary to establish common definitions and grading systems allowing not only for efficient treatment but allocating adequate medical resources to reach this goal.


Asunto(s)
Desnutrición/rehabilitación , Neoplasias/terapia , Apoyo Nutricional/métodos , Cuidados Paliativos/métodos , Calidad de Vida , Supervivientes de Cáncer/psicología , Terapia Combinada , Consejo/métodos , Suplementos Dietéticos , Ingestión de Alimentos/fisiología , Ejercicio Físico/fisiología , Humanos , Cuidados a Largo Plazo/métodos , Desnutrición/diagnóstico , Desnutrición/etiología , Desnutrición/metabolismo , Estadificación de Neoplasias , Neoplasias/complicaciones , Neoplasias/metabolismo , Neoplasias/patología , Estado Nutricional/fisiología , Grupo de Atención al Paciente , Apoyo Social
17.
Nutr Diet ; 75(1): 117-122, 2018 02.
Artículo en Inglés | MEDLINE | ID: mdl-29411490

RESUMEN

AIM: The aim of the present study was to determine if the Malnutrition Screening Tool (MST) is valid for use within the Community Rehabilitation Program (CRP) setting. Secondary outcome measures were to assess malnutrition prevalence in the CRP population and to determine trends between malnutrition and age, body mass index (BMI) and falls history. METHODS: This study used a cross-sectional design. All clients admitted to a Melbourne metropolitan CRP during the study period had the MST completed at intake. A total of 160 participants were then selected at random and a Subjective Global Assessment (SGA) was completed by an experienced dietitian. Participants were classified as well nourished or malnourished, and this result was compared to their MST score. Data analysis was completed to determine the predictive value of the MST compared to SGA, which was expressed using sensitivity, specificity, positive and negative predictive values. RESULTS: Out of the 160 participants, 34.0% were identified as malnourished. The MST achieved a sensitivity of 72.2% and a specificity of 83.8% with positive predictive value of 69.6% and negative predictive value of 85.4% compared to the SGA. Participants in the malnourished group were older and had a lower BMI (P < 0.05). CONCLUSIONS: Considering the demographics and needs of the CRP population group and the predictive value of the MST compared to SGA, it can be concluded that the MST is a valid screening tool for use in this population and has relatively low burden to complete. Consequently, the MST could be included in the client initial needs identification to be completed when admitted to the program.


Asunto(s)
Desnutrición/rehabilitación , Tamizaje Masivo , Evaluación Nutricional , Anciano , Australia , Estudios Transversales , Femenino , Humanos , Masculino , Desnutrición/epidemiología , Persona de Mediana Edad , Factores de Riesgo
18.
Nutr Diet ; 75(3): 283-290, 2018 07.
Artículo en Inglés | MEDLINE | ID: mdl-29392865

RESUMEN

AIM: Nutritional decline during and after acute hospitalisation is common amongst older people. This quality improvement initiative aimed to introduce a dietitian-led discharge planning and follow-up program (Hospital to Home Outreach for Malnourished Elders, HHOME) at two hospitals within usual resources to improve nutritional and functional recovery. METHODS: Prospective pre-post evaluation design was used. Medical patients aged 65+ years at-risk of malnutrition and discharged to independent living were eligible. Participants receiving nutrition discharge planning and dietetic telephone follow up for four weeks post-discharge ('HHOME') were compared to usual care ('pre-HHOME'). Nutritional (weight and mini nutritional assessment (MNA)), functional (gait speed, handgrip strength and modified Barthel index) and assessment of quality of life-6D (AQoL-6D) outcomes were measured on discharge and six weeks later. RESULTS: At six weeks, no significant difference in nutritional status was observed between pre-HHOME (n = 39) and HHOME cohorts, although the HHOME cohort on average maintained weight while pre-HHOME cohort lost weight (0.4 ± 2.9 kg vs -1.0 ± 3.7 kg, P = 0.060). Greater improvement in gait speed was seen in HHOME group (+0.24 ± 0.27 vs +0.11 ± 0.22, P = 0.046) with no other significant outcome improvements. Across both cohorts, half were readmitted to hospital and 10% died within 12 weeks post-discharge. CONCLUSIONS: The nutritional discharge planning and dietetic follow up provided to older community-living malnourished patients made a small impact on nutritional and functional parameters but clinical outcomes remained poor.


Asunto(s)
Continuidad de la Atención al Paciente/organización & administración , Dietética/organización & administración , Evaluación Geriátrica/métodos , Desnutrición/diagnóstico , Evaluación Nutricional , Alta del Paciente , Anciano , Femenino , Estudios de Seguimiento , Humanos , Vida Independiente , Masculino , Desnutrición/prevención & control , Desnutrición/rehabilitación , Estado Nutricional , Estudios Prospectivos , Calidad de Vida
19.
Clin. biomed. res ; 38(3): 265-272, 2018.
Artículo en Inglés | LILACS | ID: biblio-1046875

RESUMEN

Introduction: Part of the prognosis of hospitalized patient depends on nutritional status and the safety and efficacy of the feeding administration route. Therefore, the aim of this study was to identify data on the indication of nasoenteric tube (NET) prescription to analyze the profile of these patients. Methods: A retrospective cross-sectional study was carried out with data collection in medical records of patients over 18 years of age, of both sexes, treated at the Emergency Adult Service (EAS), using NET. Results: there was a predominance of females (51.9%); neurological disease was the most prevalent underlying disease, and 57.8% had more than one diagnosed disease. Malnutrition, bronchopneumonia, and dysphagia were present in 23.6%, 27% and 40% of the cases, respectively. There was a request for speech-language evaluation in only 8.7% of the patients. And 80.7% did not use NET prior to emergency care. Regarding the indications for the use of NET by group of underlying disease, low food intake was the most prevalent clinical reason described in the medical records, followed by dysphagia, with a higher prevalence of patients taking NET for nutritional reasons. There was no justification for prescription in 15.2% of the sample. There was an association between the variables bronchopneumonia and dysphagia (p = 0.01). Conclusion: It was verified that in the studied population there are risk factors for dysphagia. The analysis of the population profile in the present study contributed to increased knowledge and information about this population regarding the criteria for indication of the use of the alternative route. (AU)


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Anciano , Anciano de 80 o más Años , Trastornos de Deglución/complicaciones , Nutrición Enteral/efectos adversos , Trastornos de Deglución/terapia , Nutrición Enteral/métodos , Desnutrición/rehabilitación , Servicio de Urgencia en Hospital
20.
J Nutr Health Aging ; 21(7): 811-818, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-28717811

RESUMEN

OBJECTIVES: We examined if individually-adapted nutritional counselling could prevent > 5% weight loss among elderly patients 3 months after discharge from a rehabilitation institution. In addition we assessed quality of life (QoL) and appetite. DESIGN: An open, randomized trial. SETTING: Godthaab Health and Rehabilitation Institution in Bærum, Norway. PARTICIPANTS: Patients identified as being undernourished or at risk of disease-related malnutrition using the Nutritional Risk Screening tool NRS-2002. INTERVENTION: Shortly before discharge, patients in the intervention group received an individually-tailored nutrition plan. During the subsequent 3 months these patients were contacted 3 times via telephone calls and they received one visit at their homes, for nutrition counselling. Focus on this counselling was on optimizing meal environment, improving appetite, increasing food intake, advice on food preparation, and motivation and support. MEASUREMENTS: In addition to weight, QoL and appetite were assessed using the EQ-5D questionnaire and a modified version of the Disease-Related Appetite Questionnaire, respectively. RESULTS: Among 115 considered eligible for the study, 100 were enrolled (72 women and 28 men), with a mean age of 75 years and a mean body mass index of 20 kg/m2. Two in the intervention group (n = 52) and 5 in the control group (n = 48) lost > 5% of their body weight, giving an odds ratio of 0.34 (95% CI: 0.064 - 1.86; p = 0.22). We did not detect any significant differences in the QoL- or appetite scores between the two study groups after three months. CONCLUSION: An individually-adapted nutritional counselling did not improve body mass among elderly patients 3 months after discharge from a rehabilitation institution. Neither quality of life nor appetite measures were improved. Possibly, nutritional counselling should be accompanied with nutritional supplementation to be effective in this vulnerable group of elderly. The trial is registered in Clinical Trials (ID: NCT01632072).


Asunto(s)
Apetito , Peso Corporal , Desnutrición/dietoterapia , Calidad de Vida , Anciano , Índice de Masa Corporal , Consejo , Determinación de Punto Final , Femenino , Hogares para Ancianos , Humanos , Masculino , Desnutrición/rehabilitación , Noruega , Casas de Salud , Alta del Paciente , Encuestas y Cuestionarios
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