1.
J Pediatr
; 184: 227-229.e1, 2017 05.
Artículo
en Inglés
| MEDLINE
| ID: mdl-28284481
RESUMEN
In all surviving girls with Leigh syndrome, French Canadian variety, a mitochondrial disease, we detected premature ovarian failure, manifested as absent or arrested breast development, lack of menarche, high follicle-stimulating hormone, a prepubertal uterus, and small ovaries. Pubertal onset and progression should be evaluated in girls with mitochondrial diseases.