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1.
Eur J Gastroenterol Hepatol ; 34(1): 104-111, 2022 01 01.
Artículo en Inglés | MEDLINE | ID: mdl-33852508

RESUMEN

OBJECTIVE: Diabetes is the fifth leading cause of death in the People's Republic of China. The aim of the article is to compare the effects of nursing care on the laboratory findings and ultrasound results of diabetic patients with chronic liver diseases (CLD) who were treated with antiglycemic drugs. METHODS: Diabetic were patients treated with metformin hydrochloride in combination with gliclazide, pioglitazone hydrochloride, sitagliptin, exenatide or liraglutide. Non-alcoholic fatty liver disease (NAFLD) was evaluated by abdominal ultrasound, and fibrosis stages were evaluated at baseline and 8 months. All the patients were equally divided into two groups depending on the therapeutic approach. RESULTS: The first group of patients additionally received nursing care, and the second group adhered to the prescribed therapy on their own. In total 90 patients, or 55.6%, had NAFLD at baseline, and its course was dependent upon changes in the weight (P = 0.009) and waist circumference (P = 0.012). The proportions of patients who demonstrated an ultrasonographic improvement in the control group were: 24 (56.8%) with gliclazide, 15 (41.3%) with pioglitazone hydrochloride, 28 (66.1%) with sitagliptin, 16 (79%) with exenatide and 15 (66.7%) with liraglutide (P = 0.2). For the group that received nursing care an ultrasonographic improvement was in: 29 (68.16%) with gliclazide, 18 (49.56%) with pioglitazone hydrochloride, 33 (79.32%) with sitagliptin, 19 (94.8%) with exenatide and 21 80.04% with liraglutide (P = 0.2). CONCLUSIONS: Outcomes from the type 2 diabetes treatment paralleling of CLD were presented. Treatment of type 2 diabetes with pioglitazone hydrochloride, gliclazide, sitagliptin, liraglutide and exenatide was proven effective.


Asunto(s)
Diabetes Mellitus Tipo 2 , Hipoglucemiantes , Enfermedad del Hígado Graso no Alcohólico , Diabetes Mellitus Tipo 2/tratamiento farmacológico , Diabetes Mellitus Tipo 2/enfermería , Exenatida/efectos adversos , Gliclazida/efectos adversos , Humanos , Hipoglucemiantes/efectos adversos , Liraglutida/efectos adversos , Metformina/efectos adversos , Enfermedad del Hígado Graso no Alcohólico/diagnóstico por imagen , Enfermedad del Hígado Graso no Alcohólico/tratamiento farmacológico , Enfermedad del Hígado Graso no Alcohólico/enfermería , Pioglitazona/efectos adversos , Fosfato de Sitagliptina/efectos adversos
2.
Nursing ; 50(3): 32-39, 2020 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-32068703

RESUMEN

Nonalcoholic fatty liver disease (NAFLD) is defined as storage of excess fat in the liver not caused by heavy alcohol consumption. Nonalcoholic steatohepatitis is the severe form of NAFLD. This article discusses causes, diagnosis, and nursing interventions for patients with either disorder.


Asunto(s)
Enfermedad del Hígado Graso no Alcohólico/enfermería , Humanos , Síndrome Metabólico , Enfermedad del Hígado Graso no Alcohólico/etiología , Evaluación en Enfermería , Diagnóstico de Enfermería , Educación del Paciente como Asunto , Factores de Riesgo , Índice de Severidad de la Enfermedad
3.
Clin Gastroenterol Hepatol ; 17(10): 2132-2133, 2019 09.
Artículo en Inglés | MEDLINE | ID: mdl-30448600

RESUMEN

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, affecting nearly 1 in 3 Americans.1 Nonalcoholic steatohepatitis (NASH), the clinically aggressive variant of NAFLD, has a propensity of fibrosis progression and increased risk of cirrhosis and hepatocellular carcinoma. NASH-related cirrhosis is now the most rapidly growing indication for liver transplantation (LT).2 Disease recurrence and progression to advanced fibrosis after LT are high3; however, the key contributors of these are unknown. We hypothesized that patients with NASH cirrhosis reside in a microenvironment conducive to not only development of NASH but also fibrosis progression, which likely persist after LT and contribute to disease recurrence. The hypothesis was tested by performing vibration-controlled transient elastography (VCTE) in primary caregivers and cohabitants of patients with decompensated cirrhosis awaiting LT.


Asunto(s)
Cuidadores/estadística & datos numéricos , Cirrosis Hepática/enfermería , Hígado/diagnóstico por imagen , Enfermedad del Hígado Graso no Alcohólico/epidemiología , Hijos Adultos/estadística & datos numéricos , Anciano , Alanina Transaminasa/metabolismo , Aspartato Aminotransferasas/metabolismo , Diabetes Mellitus/epidemiología , Dieta/estadística & datos numéricos , Carbohidratos de la Dieta , Grasas de la Dieta , Dislipidemias/epidemiología , Diagnóstico por Imagen de Elasticidad , Ingestión de Energía , Ácidos Grasos , Femenino , Humanos , Hipertensión/epidemiología , Cirrosis Hepática/etiología , Trasplante de Hígado , Masculino , Persona de Mediana Edad , Enfermedad del Hígado Graso no Alcohólico/complicaciones , Enfermedad del Hígado Graso no Alcohólico/diagnóstico por imagen , Enfermedad del Hígado Graso no Alcohólico/enfermería , Padres , Prevalencia , Índice de Severidad de la Enfermedad , Sodio en la Dieta , Esposos/estadística & datos numéricos
4.
Gastroenterol Nurs ; 41(5): 424-426, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-30272604

RESUMEN

The incidence of nonalcoholic fatty liver disease (NAFLD) has increased over the past few decades because of the obesity epidemic and is also strongly associated with diabetes Type 2. Patients often present asymptomatically until the liver disease becomes advanced. Alternatively, persons with NAFLD can present with various stages of inflammation, hepatosis, or fibrosis, which can eventually result in cirrhosis and lead to hepatocellular carcinoma. Lifestyle modifications are the most important aspects of cirrhosis prevention. These changes are crucial because cirrhosis is a known cause of long-term liver disease. Nurse practitioners play an important role in the early detection of NAFLD and prevention of its potentially life-threatening complications.


Asunto(s)
Estilo de Vida Saludable , Enfermedad del Hígado Graso no Alcohólico/diagnóstico , Enfermedad del Hígado Graso no Alcohólico/enfermería , Enfermeras Practicantes , Rol de la Enfermera , Educación del Paciente como Asunto/métodos , Carcinoma Hepatocelular/etiología , Carcinoma Hepatocelular/prevención & control , Manejo de la Enfermedad , Progresión de la Enfermedad , Femenino , Humanos , Cirrosis Hepática/etiología , Cirrosis Hepática/prevención & control , Neoplasias Hepáticas/etiología , Neoplasias Hepáticas/prevención & control , Masculino , Enfermedad del Hígado Graso no Alcohólico/complicaciones , Pronóstico , Medición de Riesgo , Resultado del Tratamiento
7.
Nurse Pract ; 42(7): 14-20, 2017 07 15.
Artículo en Inglés | MEDLINE | ID: mdl-28562448

RESUMEN

Nonalcoholic fatty liver disease (NAFLD) is the leading cause of liver disease in the United States and will soon be the leading indication for liver transplantation. NAFLD can lead to cirrhosis of the liver and is usually asymptomatic. Prompt referral to a hepatologist may halt the morbidity and mortality associated with NAFLD.


Asunto(s)
Enfermedad del Hígado Graso no Alcohólico/epidemiología , Humanos , Incidencia , Enfermedad del Hígado Graso no Alcohólico/enfermería , Enfermedad del Hígado Graso no Alcohólico/fisiopatología , Diagnóstico de Enfermería , Estados Unidos/epidemiología
8.
Nurs Stand ; 30(52): 15, 2016 Aug 24.
Artículo en Inglés | MEDLINE | ID: mdl-27641564

RESUMEN

Essential facts Non-alcoholic fatty liver disease (NAFLD) is an excess of fat in the liver that is not the result of excessive alcohol consumption or other secondary causes, such as hepatitis C. According to the National Institute for Health and Care Excellence, fatty liver - steatosis - affects between 20% and 30% of the population and its prevalence is increasing.


Asunto(s)
Enfermedad del Hígado Graso no Alcohólico/diagnóstico , Enfermedad del Hígado Graso no Alcohólico/terapia , Humanos , Enfermedad del Hígado Graso no Alcohólico/enfermería , Enfermedad del Hígado Graso no Alcohólico/fisiopatología , Relaciones Enfermero-Paciente , Factores de Riesgo
9.
Nurs N Z ; 22(11): 20-24, 2016 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-30556967

RESUMEN

IMPAIRED LIVER function affects every aspect of the body's physiology. Diseases of the liver have more widespread and life-threatening impacts than malfunctioning of any of the body's other conditions. accessory organs. Non-alcoholic fatty Liver disease rates are soaring, concurrent with the obesity epidemic and increasing rates of type 2 diabetes. Alcoholic liver disease and viral hepatitis also contribute to high rates of liver damage in the population, making liver disease one of the commonest causes premature death. Liver transplants, hepatocellular carcinomas, and deaths from Liver disease are increasingly due to preventable or treatable liver conditions. Understanding normal liver function allows nurses to predict the impact of Liver disease on their patients' health and well-being. Knowledge of underlying causes of impaired liver function enhances our ability to support and counsel those who are at risk of, or have been diagnosed with liver disease.


Asunto(s)
Hepatopatías/enfermería , Hígado/fisiología , Carcinoma Hepatocelular/metabolismo , Carcinoma Hepatocelular/enfermería , Carcinoma Hepatocelular/fisiopatología , Hepatitis Viral Humana/metabolismo , Hepatitis Viral Humana/enfermería , Hepatitis Viral Humana/fisiopatología , Humanos , Hígado/citología , Hígado/metabolismo , Hepatopatías/metabolismo , Hepatopatías/fisiopatología , Hepatopatías Alcohólicas/metabolismo , Hepatopatías Alcohólicas/enfermería , Hepatopatías Alcohólicas/fisiopatología , Pruebas de Función Hepática , Neoplasias Hepáticas/metabolismo , Neoplasias Hepáticas/enfermería , Neoplasias Hepáticas/fisiopatología , Trasplante de Hígado/enfermería , Enfermedad del Hígado Graso no Alcohólico/metabolismo , Enfermedad del Hígado Graso no Alcohólico/enfermería , Enfermedad del Hígado Graso no Alcohólico/fisiopatología
10.
Nurse Pract ; 40(11): 36-42; quiz 42-3, 2015 Nov 15.
Artículo en Inglés | MEDLINE | ID: mdl-26474202

RESUMEN

Nonalcoholic fatty liver disease (NAFLD) is becoming a worldwide health crisis. It is important for NPs to understand the spectrum of NAFLD. Although lifestyle modifications are the first-line treatment, the NP should be aware of current and future medication management to help the patient live a healthy life.


Asunto(s)
Enfermedad del Hígado Graso no Alcohólico/enfermería , Enfermeras Practicantes , Guías de Práctica Clínica como Asunto , Competencia Clínica , Humanos , Estilo de Vida , Enfermedad del Hígado Graso no Alcohólico/tratamiento farmacológico , Enfermedad del Hígado Graso no Alcohólico/epidemiología , Enfermedad del Hígado Graso no Alcohólico/fisiopatología , Diagnóstico de Enfermería , Factores de Riesgo
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