RESUMEN
OBJECTIVES: An unexpectedly low word recognition (WR) score may be taken as evidence of increased risk for retrocochlear tumor. We sought to develop evidence for or against using a standardized WR (sWR) score in detecting retrocochlear tumors. The sWR is a z score expressing the difference between an observed WR score and a Speech Intelligibility Index-based predicted WR score. We retrospectively compared the sensitivity and specificity of pure-tone asymmetry-based logistic regression models that incorporated either the sWR or the raw WR scores in detecting tumor cases. Two pure-tone asymmetry calculations were used: the 4-frequency pure-tone asymmetry (AAO) calculation of the American Academy of Otolaryngology-Head and Neck Surgery and a 6-frequency pure-tone asymmetry (6-FPTA) calculation previously optimized to detect retrocochlear tumors. We hypothesized that a regression model incorporating the 6-FPTA calculation and the sWR would more accurately detect retrocochlear tumors. DESIGN: Retrospective data from all patients seen in the audiology clinic at Mayo Clinic in Florida in 2016 were reviewed. Cases with retrocochlear tumors were compared with a reference group with noise- or age-related hearing loss or idiopathic sensorineural hearing loss. Two pure-tone-based logistic regression models were created (6-FPTA and AAO). Into these base models, WR variables (WR, sWR, WR asymmetry [WRΔ], and sWR asymmetry [sWRΔ]) were added. Tumor detection performance for each regression model was compared twice: first, using all qualifying cases (61 tumor cases; 2332 reference group cases), and second, using a data set filtered to exclude hearing asymmetries greater than would be expected from noise-related or age-related hearing loss (25 tumor cases; 2208 reference group cases). The area under the curve and the DeLong test for significant receiver operating curve differences were used as outcome measures. RESULTS: The 6-FPTA model significantly outperformed the AAO model-with or without the addition of WR or WRΔ variables. Including sWR into the AAO base regression model significantly improved disease detection performance. Including sWR into the 6-FPTA model significantly improved disease detection performance when large hearing asymmetries were excluded. In the data set that included large pure-tone asymmetries, area under the curve values for the 6-FPTA + sWR and AAO + sWR models were not significantly better than the base 6-FPTA model. CONCLUSIONS: The results favor the superiority of the sWR computational method in identifying reduced WR scores in retrocochlear cases. The utility would be greatest where undetected tumor cases are embedded in a population heavily representing age- or noise-related hearing loss. The results also demonstrate the superiority of the 6-FPTA model in identifying tumor cases. The 2 computational methods may be combined (ie, the 6-FPTA + sWR model) into an automated tool for detecting retrocochlear disease in audiology and community otolaryngology clinics. The 4-frequency AAO-based regression model was the weakest detection method considered. Including raw WR scores into the model did not improve performance, whereas including sWR into the model did improve tumor detection performance. This further supports the contribution of the sWR computational method for recognizing low WR scores in retrocochlear disease cases.
Asunto(s)
Pérdida Auditiva Sensorineural , Neoplasias , Presbiacusia , Enfermedades Retrococleares , Humanos , Estudios Retrospectivos , Pérdida Auditiva Sensorineural/diagnóstico , Presbiacusia/diagnóstico , Audiometría de Tonos Puros/métodosRESUMEN
RESUMO Objetivo Caracterizar as avaliações seqüenciais do potencial evocado auditivo de tronco encefálico em recém-nascidos infectados pelo Zika vírus, correlacionando com a presença de microcefalia e com os sintomas de Zika nas mães durante a gestação. Métodos Estudo descritivo, longitudinal e quantitativo, do qual participaram 20 recém-nascidos, filhos de mães infectadas pelo Zika vírus no período gestacional. Foram analisados os prontuários desses bebês, que passaram por duas avaliações eletrofisiológicas, uma no primeiro mês de vida e outra, após 6 meses. Os dados comparativos foram tabulados e analisados por meio de estatística descritiva e inferencial. Resultados Setenta por cento dos bebês apresentaram microcefalia e 55% das mães tiveram os sintomas da infecção pelo Zika no primeiro trimestre de gestação. Não houve alteração significativa dos limiares eletrofisiológicos em nenhum dos momentos. Houve mudança estatisticamente significativa, principalmente das latências das ondas III e V, entre os exames, caracterizando maturação da via auditiva nos bebês. Não foi encontrada correlação entre a microcefalia e alterações nas latências do PEATE. Conclusão Bebês portadores de Zika apresentaram limiares eletrofisiológicos dentro da normalidade e diminuição das latências absolutas das ondas III e V e interpicos, confirmando a ação citotóxica do Zika. Houve dois casos de piora significativa do limiar eletrofisiológico. Não foi observada correlação entre resultados do PEATE e época de aparecimento dos sintomas durante a gestação, ou a presença de microcefalia.
ABSTRACT Purpose To characterize sequential assessments of auditory brainstem responses in newborns infected by zika virus, correlating with presence of microcephaly and with Zika virus symptoms in mothers during pregnancy. Methods A descriptive, longitudinal and quantitative study, in which 20 newborns, children of mothers infected by Zika virus during pregnancy, participated. Medical records of these babies were analyzed, and they underwent two electrophysiological assessments, one in the first month of life and the other, after 6 months. Comparative data were tabulated and analyzed using descriptive and inferential statistics. Results Seventy percent of babies had microcephaly and 55% of mothers had symptoms of Zika infection in the first trimester of pregnancy. There was no significant alteration in electrophysiological thresholds at any moments. There was a statistically significant change, mainly in the latencies of waves III and V, between the tests, characterizing maturation of the auditory pathway in babies. No correlation was found between microcephaly and changes in ABR latencies. Conclusion Babies with Zika had normal electrophysiological thresholds and decreased absolute latencies of waves III and V and interpeaks, confirming the cytotoxic action of Zika. There were two cases of significant worsening of the electrophysiological threshold. There was no correlation between ABR results and time of onset of the symptoms during pregnancy, or presence of microcephaly.
Asunto(s)
Humanos , Femenino , Embarazo , Recién Nacido , Lactante , Enfermedades Retrococleares/diagnóstico , Potenciales Evocados Auditivos del Tronco Encefálico/fisiología , Infección por el Virus Zika/complicaciones , Microcefalia/fisiopatología , Primer Trimestre del Embarazo , Estimulación Acústica , Brasil , Tamizaje Neonatal , Electrofisiología , Pérdida Auditiva SensorineuralRESUMEN
OBJECTIVES: To describe the occurrence of both peripheral and central auditory system dysfunction in sickle cell anaemia (SCA) patients and discuss the different mechanisms hypothesised to be responsible for these alterations. METHODS: An electronic search was conducted using PubMed Central® (MEDLINE), LILACS® and Scopus® databases. This systematic review was performed in accordance with the PRISMA statement. Original observational studies that utilised audiological tests for auditory system evaluations in SCA were included. RESULTS: A total of 183 records were found in the databases searched. Twenty-one of these studies met the inclusion criteria. Pooled prevalence of sensorineural hearing loss (SNHL) was 20.5% (CI: 10.3-33%). Retrocochlear involvement was detected with the auditory brainstem response, which assesses integrity of the cochlea, 8th cranial nerve and brainstem structures. In addition, the increase in otoacoustic emission amplitudes in SCA patients indicates changes in cochlear micromechanics and precedes the expression of a detectable cochlear pathology. CONCLUSION: The prevalence of the SNHL is higher than in the general population. Dysfunction of the auditory system may be present in SCA patients, with the most probable mechanism being the presence of circulatory disturbances resulting from the chronic inflammatory state of the disease.
DYSFONCTIONNEMENT DU SYSTÈME AUDITIF DANS L'ANÉMIE FALCIFORME: REVUE SYSTÉMATIQUE ET MÉTA-ANALYSE: OBJECTIFS: Décrire l'apparition de dysfonctionnements du système auditif périphérique et central chez les patients atteints d'anémie falciforme (AF) et discuter des différents mécanismes supposés responsables de ces altérations. MÉTHODES: Une recherche électronique a été effectuée dans les bases de données PubMed Central® (MEDLINE), LILACS® et Scopus® . Cette revue systématique a été réalisée conformément au PRISMA Statement. Des études observationnelles originales utilisant des tests audiologiques pour évaluer le système auditif dans l'AF ont été incluses. RÉSULTATS: Un total de 183 enregistrements ont été trouvés dans les bases de données consultées. Vingt et une de ces études répondaient aux critères d'inclusion. La prévalence poolée de la perte auditive neurosensorielle (SNHL) était de 20,5% (IC: 10,3% à 33%). L'atteinte rétrocochléaire a été détectée avec la réponse du tronc cérébral auditif, qui évalue l'intégrité de la cochlée, du huitième nerf crânien et de la structure du tronc cérébral. De plus, l'augmentation des amplitudes des émissions otoacoustiques chez les patients atteints de l'AF indique des modifications de la micromécanique cochléaire et précède l'expression d'une pathologie cochléaire détectable. CONCLUSION: La prévalence de la SNHL est plus élevée que dans la population générale. Un dysfonctionnement du système auditif peut être présent chez les patients AF, le mécanisme le plus probable étant la présence de troubles circulatoires résultant de l'état inflammatoire chronique de la maladie.
Asunto(s)
Anemia de Células Falciformes/epidemiología , Pérdida Auditiva Sensorineural/epidemiología , Adolescente , Niño , Potenciales Evocados Auditivos del Tronco Encefálico/fisiología , Femenino , Humanos , Masculino , Emisiones Otoacústicas Espontáneas/fisiología , Enfermedades Retrococleares/epidemiologíaAsunto(s)
Enfermedades Cocleares/diagnóstico por imagen , Pérdida Auditiva Sensorineural/diagnóstico , Imagen por Resonancia Magnética/métodos , Enfermedades Retrococleares/diagnóstico por imagen , Tomografía Computarizada por Rayos X/métodos , Cóclea/diagnóstico por imagen , Enfermedades Cocleares/complicaciones , Pérdida Auditiva Sensorineural/etiología , Humanos , Enfermedades Retrococleares/complicaciones , Nervio Vestibulococlear/diagnóstico por imagenRESUMEN
Diagnosis of retrocochlear lesions is a relatively frequent issue of otolaryngological practice, the omission of which may have serious consequences for the patient. Properly set clinical guidelines and diagnostic protocols are thus one of the key aspects of good clinical practice. There are two methods available: the first is an audiological diagnosis with ABR as the primary tool to determine a group of patients with a possible tumour with subsequent MRI; the second is to examine the MRI in each patient with a clinical suspicion of a CPA tumour. The sensitivity of both diagnostic methods in relation to cost-effectiveness is discussed.
Asunto(s)
Pérdida Auditiva Sensorineural , Enfermedades Retrococleares , Humanos , Imagen por Resonancia MagnéticaRESUMEN
OBJECTIVES: Quantify number of MRI scans obtained in a tertiary neurotology practice and identify likelihood of pathologic findings. STUDY DESIGN: Retrospective cohort study. SETTING: Tertiary neurotology center. SUBJECTS AND METHODS: A retrospective analysis of all adult patients over 20â¯months (3/2012-10/2013) where MRI was deemed necessary for evaluation of neurotologic complaints. Demographics, clinical history, physical examination, and audiometric findings were used to categorize new patients into 7 groups: definite Meniere's disease (MD), probable MD, possible MD, vague dizziness, tinnitus only, asymmetric hearing loss (HL), and other symptoms to stratify risk for retrocochlear tumor and other relevant pathology. RESULTS: 1537 MRI scans were performed, 932 of these were for a new diagnosis. Discovering retrocochlear tumors was rare (1.4%). Patients with HL had a 0.3% (1/314) chance of retrocochlear tumor and 3.2% (10/314) chance of relevant pathology. Patients with only unilateral tinnitus had no evidence of retrocochlear tumors, and 3.8% chance of finding relevant pathology. Patients with "definite" or "probable" MD had no evidence of retrocochlear tumor or other relevant findings. All discovered acoustic neuromas were in the "possible MD" category, which had a 9.3% chance of finding all relevant pathology. CONCLUSIONS: In a tertiary neurotology center, the likelihood of finding a retrocochlear tumor on MRI is rare. In the current study, unilateral tinnitus exclusively, "definite MD," and "probable MD" failed to yield a single example of retrocochlear tumor. Patients with "possible MD" had the highest probability of finding retrocochlear tumors and other relevant pathology.
Asunto(s)
Encéfalo/diagnóstico por imagen , Oído Interno/diagnóstico por imagen , Imagen por Resonancia Magnética , Enfermedad de Meniere/diagnóstico por imagen , Enfermedades Retrococleares/diagnóstico por imagen , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Mareo/diagnóstico por imagen , Mareo/etiología , Femenino , Pérdida Auditiva/diagnóstico por imagen , Pérdida Auditiva/etiología , Humanos , Masculino , Enfermedad de Meniere/etiología , Persona de Mediana Edad , Enfermedades Retrococleares/complicaciones , Estudios Retrospectivos , Evaluación de Síntomas , Acúfeno/diagnóstico por imagen , Acúfeno/etiología , Adulto JovenRESUMEN
PURPOSE: To report three cases of patients with Systemic Sclerosis (SSc) and retrocochlear impairments. METHODS: This is a case report of three individuals with SSc and retrocochlear impairments assisted at a rheumatology outpatient clinic. All individuals underwent Brainstem Auditory Evoked Potential (BAEP) and, when necessary, audiometry. RESULTS: All three individuals presented sensorineural hearing loss. Although no retrocochlear impairment was identified in the basic audiologic evaluation, the BAEP results were altered. CONCLUSION: Retrocochlear impairments were present in the individuals under study, both in the absolute latencies and interpeak interval, thereby demanding the attention of rheumatologists and speech-language pathologists to such changes during the monitoring of SSc patients. The results also show a need for epidemiological studies on the theme.
OBJETIVO: Relatar três casos de pacientes portadores de Esclerose Sistêmica e que apresentaram alterações retrococleares. MÉTODO: Trata-se de um estudo de relato de casos de três indivíduos com esclerose sistêmica e alteração retrococlear, acompanhados em um serviço de reumatologia. Todos os pacientes realizaram o Potencial Evocado Auditivo de Tronco Encefálico e, quando necessário, nova audiometria. RESULTADOS: Todos os indivíduos apresentaram perda auditiva do tipo sensorioneural. Não foi identificado na avaliação audiológica básica qualquer resultado que sugerisse alteração retrococlear, porém o PEATE apresentou-se alterado. CONCLUSÃO: Pode-se concluir que o estudo revela alterações retrococleares nesta população, ocorrendo tanto nas latências absolutas quanto no intervalo interpico. E, neste contexto, reumatologistas e fonoaudiólogos, ao acompanharem pacientes com esclerose sistêmica, devem estar atentos para a possibilidade da ocorrência dessa alteração nessa população. Revela também, a necessidade de estudos epidemiológicos sobre o tema.
Asunto(s)
Pérdida Auditiva Sensorineural/etiología , Esclerodermia Sistémica/complicaciones , Anciano , Audiometría de Respuesta Evocada , Umbral Auditivo , Potenciales Evocados Auditivos del Tronco Encefálico , Femenino , Humanos , Masculino , Persona de Mediana Edad , Enfermedades Retrococleares/etiologíaRESUMEN
RESUMO Objetivo Relatar três casos de pacientes portadores de Esclerose Sistêmica e que apresentaram alterações retrococleares. Método Trata-se de um estudo de relato de casos de três indivíduos com esclerose sistêmica e alteração retrococlear, acompanhados em um serviço de reumatologia. Todos os pacientes realizaram o Potencial Evocado Auditivo de Tronco Encefálico e, quando necessário, nova audiometria. Resultados Todos os indivíduos apresentaram perda auditiva do tipo sensorioneural. Não foi identificado na avaliação audiológica básica qualquer resultado que sugerisse alteração retrococlear, porém o PEATE apresentou-se alterado. Conclusão Pode-se concluir que o estudo revela alterações retrococleares nesta população, ocorrendo tanto nas latências absolutas quanto no intervalo interpico. E, neste contexto, reumatologistas e fonoaudiólogos, ao acompanharem pacientes com esclerose sistêmica, devem estar atentos para a possibilidade da ocorrência dessa alteração nessa população. Revela também, a necessidade de estudos epidemiológicos sobre o tema.
ABSTRACT Purpose To report three cases of patients with Systemic Sclerosis (SSc) and retrocochlear impairments. Methods This is a case report of three individuals with SSc and retrocochlear impairments assisted at a rheumatology outpatient clinic. All individuals underwent Brainstem Auditory Evoked Potential (BAEP) and, when necessary, audiometry. Results All three individuals presented sensorineural hearing loss. Although no retrocochlear impairment was identified in the basic audiologic evaluation, the BAEP results were altered. Conclusion Retrocochlear impairments were present in the individuals under study, both in the absolute latencies and interpeak interval, thereby demanding the attention of rheumatologists and speech-language pathologists to such changes during the monitoring of SSc patients. The results also show a need for epidemiological studies on the theme.
Asunto(s)
Humanos , Masculino , Femenino , Anciano , Esclerodermia Sistémica/complicaciones , Pérdida Auditiva Sensorineural/etiología , Enfermedades Retrococleares/etiología , Audiometría de Respuesta Evocada , Umbral Auditivo , Potenciales Evocados Auditivos del Tronco Encefálico , Persona de Mediana EdadRESUMEN
Abstract Introduction Treatment for auditory neuropathy spectrum disorder (ANSD) is not yet well established, including the use of hearing aids (HAs). Not all patients diagnosed with ASND have access to HAs, and in some cases HAs are even contraindicated. Objective To monitor the hearing handicap and the recognition threshold of sentences in silence and in noise in a patient with ASND using an HA. Resumed Report A 47-year-old woman reported moderate sensorineural hearing loss in the right ear and high-frequency loss of 4 kHz in the left ear, with bilateral otoacoustic emissions. Auditory brainstem response suggested changes in the functioning of the auditory pathway (up to the inferior colliculus) on the right. An HA was indicated on the right. The patient was tested within a 3-month period before the HA fitting with respect to recognition threshold of sentences in quiet and in noise and for handicap determination. After HA use, she showed a 2.1-dB improvement in the recognition threshold of sentences in silence, a 6.0-dB improvement for recognition threshold of sentences in noise, and a rapid improvement of the signal-to-noise ratio from +3.66 to -2.4 dB when compared with the same tests before the fitting of the HA. Conclusion There was a reduction of the auditory handicap, although speech perception continued to be severely limited. There was a significant improvement of the recognition threshold of sentences in silence and in noise and of the signal-to-noise ratio after 3 months of HA use.
Asunto(s)
Humanos , Femenino , Adulto , Pérdida Auditiva Bilateral , Pruebas Auditivas , Imagen por Resonancia Magnética , Audífonos , Enfermedades RetrococlearesRESUMEN
A speech discrimination test is a test using a list of 25 phonetically balanced monosyllables. It is often overlooked but significant enough for pure tone audiometry. Many physicians have performed pure tone audiometry but without a speech discrimination test. A 73-year-old woman visited our clinic complaining of sudden bilateral hearing loss. Pure tone audiometry showed only bilateral high frequency loss. However, speech discrimination had decreased markedly. We decided to follow-up after 1 week of Ginexin-F(R) (ginkgo leaf extract) and Nafril(R) (nafronyl oxalate). She felt a gait disturbance within 2 days. Magnetic resonance imaging revealed a left thalamic hemorrhage. After a 1 month hospitalization, the hematoma subsided, and speech discrimination recovered 3 months later. Acute hearing loss due to thalamic hemorrhage that recovered has never been reported. We report the first case of retrocochlear hearing loss that occurred with a thalamic hemorrhage in a patient who recovered.
Asunto(s)
Anciano , Femenino , Humanos , Audiometría , Estudios de Seguimiento , Marcha , Pérdida Auditiva , Pérdida Auditiva Bilateral , Hematoma , Hemorragia , Hospitalización , Imagen por Resonancia Magnética , Enfermedades Retrococleares , Pruebas de Discriminación del Habla , Percepción del Habla , TálamoRESUMEN
OBJECTIVES: (1) To investigate cochlear function in patients with acoustic neuroma by distortion-product otoacoustic emission tests and (2) to evaluate the utility of this method for identifying the nerve origin of acoustic neuroma. STUDY DESIGN: Diagnostic test assessment. SETTING: Community hospital. METHODS: The study included 196 patients with unilateral acoustic neuroma who were surgically treated in our hospital between April 2008 and March 2011. In all patients, pure-tone audiometry and distortion-product otoacoustic emission tests were conducted before surgery, and tumor size was measured on magnetic resonance imaging. RESULTS: Superior vestibular schwannoma (n = 112), inferior vestibular schwannoma (n = 80), and cochlear schwannoma (n = 4) were observed. Positive results of distortion-product otoacoustic emission tests were observed in 11 patients with superior vestibular schwannoma, 14 with inferior vestibular schwannoma, and 3 with cochlear schwannoma. They were predictive of cochlear schwannoma, with 75.0% sensitivity (95% confidence interval [CI], 30.6-95.4) and 87.0% specificity (95% CI, 86.1-87.4). Retrocochlear hearing loss was detected in 5 patients with inferior vestibular schwannoma and 1 with cochlear schwannoma. It was also predictive of cochlear schwannoma. This criterion showed 25.0% sensitivity (95% CI, 4.7-66.1) and 97.4% specificity (95% CI, 97.0-98.3). CONCLUSION: Percentages of patients with positive results on distortion-product otoacoustic emission tests and those with retrocochlear hearing loss differed by nerve origin. Distortion-product otoacoustic emission tests can be of some assistance in differentiating cochlear and vestibular schwannoma.
Asunto(s)
Cóclea/fisiopatología , Pérdida Auditiva Sensorineural/fisiopatología , Neuroma Acústico/fisiopatología , Emisiones Otoacústicas Espontáneas/fisiología , Adulto , Análisis de Varianza , Umbral Auditivo/fisiología , Calorimetría , Distribución de Chi-Cuadrado , Cóclea/cirugía , Femenino , Humanos , Imagen por Resonancia Magnética , Masculino , Persona de Mediana Edad , Neuroma Acústico/cirugía , Valor Predictivo de las Pruebas , Enfermedades Retrococleares/fisiopatología , Sensibilidad y Especificidad , Potenciales Vestibulares Miogénicos Evocados/fisiologíaRESUMEN
BACKGROUND AND OBJECTIVES: Unilateral auditory dysfunction such as tinnitus and hearing loss could be a warning sign of a retrocochlear lesion. Auditory brainstem response (ABR) and internal auditory canal magnetic resonance image (MRI) are suggested as novel diagnostic tools for retrocochlear lesions. However, the high cost of MRI and the low sensitivity of the ABR test could be an obstacle when assessing patients with unilateral ear symptoms. The purpose of this study was to introduce the clinical usefulness of three-dimensional fast imaging employing steady-state acquisition (3D-FIESTA) MRI in patients with unilateral ear symptoms. SUBJECTS AND METHODS: Two hundred and fifty-three patients with unilateral tinnitus or unilateral hearing loss who underwent 3D-FIESTA temporal bone MRI as a screening test were enrolled. We reviewed the abnormal findings in the 3D-FIESTA images and ear symptoms using the medical records. RESULTS: In patients with unilateral ear symptoms, 51.0% of the patients had tinnitus and 32.8% patients were assessed to have sudden sensory neural hearing loss. With 3D-FIESTA imaging, twelve patients were diagnosed with acoustic neuroma, four with enlarged vestibular aqueduct syndrome, and two with posterior inferior cerebellar artery aneurysm. Inner ear anomalies and vestibulocochlear nerve aplasia could be diagnosed with 3D-FIESTA imaging. CONCLUSIONS: 3D-FIESTA imaging is a highly sensitive method for the diagnosis of cochlear or retrocochlear lesions. 3D-FIESTA imaging is a useful screening tool for patients with unilateral ear symptoms.
Asunto(s)
Humanos , Aneurisma , Arterias , Diagnóstico , Oído , Oído Interno , Potenciales Evocados Auditivos del Tronco Encefálico , Pérdida Auditiva , Pérdida Auditiva Unilateral , Imagen por Resonancia Magnética , Tamizaje Masivo , Registros Médicos , Métodos , Neuroma Acústico , Enfermedades Retrococleares , Hueso Temporal , Acúfeno , Acueducto Vestibular , Nervio VestibulococlearRESUMEN
The Niger Delta University Teaching Hospital (NDUTH) is a young tertiary hospital with recently established department in various specialties. In spite of this it caters for the health needs of a lot of the patients in Bayelsa state and its environs. The aim of this study therefore is to audit the otorhinolaryngological (ORL) practice in this center with the aim of establishing the pattern of ORL disease which is useful for the planning of effective ORL services Methods: This is a retrospective study of patients that presented to the ear; nose and throat department of NDUTH from January 2007 to December 2011. The patient's folders and clinic records were the source of data.Results: There were 2;275 patients seen within the period under study. The age ranged from 3months to 80 years. Patients who were in the 21-30 year age group (21.1) were the most frequently seen. There were 1;150(50.55) males and 1;125(49.45) females with a male female ratio of 1.02:1. The adults were 1;725(75.82) while the children were 550(24.18). Otologic conditions ranked highest in the clinic presentations with wax impaction being the commonest ear disorder encountered. There were about 573 (25.19) procedures done within this period. Aural syringing was the commonest procedure. There was no major theatre procedures carried out.Conclusion: The otorhinolaryngologic practice in the centre is growing and otologic diseases appear to be the most common conditions seen. There is therefore need to equip both the theatre and clinic so as to offer effective care. Audiololgical services also are relevant for the rehabilitation of these patients in view of the considerable number with hearing loss. The ORL practice here appears quite elementary. Therefore there is a need to vigorously equip the department
Asunto(s)
Enfermedades del Oído , Práctica de Grupo , Empleos en Salud , Pérdida Auditiva , Hospitales , Otolaringología , Enfermedades Retrococleares , Servicios de Salud Rural , Instituciones AcadémicasRESUMEN
BACKGROUND: Superficial siderosis is a progressive disease of the central nervous system associated with chronic subarachnoid hemorrhage. Sensorineural hearing loss occurs early in the disease typically progressing to a profound hearing loss during several years and ultimately affecting 95% of patients. OBJECTIVE: There are published reports of variable outcomes regarding auditory performance for cochlear implantation in cases of superficial siderosis: the objective of this article was to systematically review this evidence. DATA SOURCES: A systematic search of NHS Evidence electronic journal databases AMED (1985 to present), BNI (1985 to present), CINAHL (1981 to present), EMBASE (1980 to present), HEALTH BUSINESS ELITE, HMIC, MEDLINE (1950 to present), and PsycINFO (1806 to present) was performed. Further research using personal communication, Google Scholar, hand searching Otology & Neurotology (2008-2011), and assessment of reference lists identified in other relevant articles yielded additional articles. STUDY SELECTION: A total of 24 articles were short-listed based on relevance; no studies were excluded on a basis of quality. Of these 24 articles, 11 were excluded. DATA EXTRACTION AND SYNTHESIS: The 13 articles included in this review report 15 cases of cochlear implantation in superficial siderosis. Of these 15 individual cases, 7 (47%) showed clear sustained benefit from cochlear implantation, 6 showed limited/no benefit from the onset, and the remaining 2 patients' initial benefit was not maintained. CONCLUSION: Outcomes will depend on the site of lesion and the degree of cochlear nerve functionality, as well as ongoing neural deterioration. Comprehensive assessment of the auditory pathway including electrical auditory brainstem response and magnetic resonance imaging as well as pre/postimplantation counseling is indicated, but these preoperative measures are imperfect predictors of outcomes. There are indications that, where the underlying disease is stable, cochlear implant performance may be sustained, and where there is disease progression (specifically regarding involvement of auditory brainstem nuclei), cochlear implant performance may deteriorate. Further data are needed in this regard; however, results suggest that earlier implantation would provide benefit for a longer period and increase cost-effectiveness.
Asunto(s)
Implantación Coclear , Siderosis/cirugía , Adolescente , Adulto , Umbral Auditivo , Niño , Preescolar , Implantes Cocleares , Análisis Costo-Beneficio , Interpretación Estadística de Datos , Femenino , Audición/fisiología , Humanos , Masculino , Persona de Mediana Edad , Enfermedades Retrococleares/cirugía , Enfermedades Retrococleares/terapia , Prueba del Umbral de Recepción del Habla , Resultado del Tratamiento , Adulto JovenRESUMEN
OBJECTIVE: The aim of this prospective study was to audiologically evaluate consecutive glaucoma patients with or without exfoliation. STUDY DESIGN: Prospective study. SETTING: Glaucoma Unit and Audiology Department at a university hospital. SUBJECTS AND METHODS: Consecutive subjects with exfoliative glaucoma (XFG) or primary open-angle glaucoma (POAG) aged between 50 and 70 years were enrolled. Auditory thresholds at 0.5, 1.0, 2.0, 4.0, and 8.0 Hz were measured bilaterally. Cochlear activity was assessed by recording distortion product otoacoustic emissions (DPOEs). Functional changes in the retrocochlear auditory pathway were evaluated by auditory brainstem responses (ABRs). RESULTS: One hundred and ten patients with XFG and 85 patients with POAG who presented in a glaucoma clinic were investigated. The mean age of study patients was 66.2 ± 5.6 years; range, 50-70 years). The odds of pathologic ABR central transmission time (interpeak latencies I-III, III-V, and I-V and waves I, III, and V) were 4.34 times higher in patients with XFG than in patients with POAG (95% confidence interval [CI], 2.22-8.49; P < .001). This significant association remained after adjusting for sex and age (odds ratio [OR] 4.12; 95% CI, 2.07-8.22; P < .001). Furthermore, the odds of ABR remained significantly higher in patients with XFG than in patients with POAG (OR 4.36; 95% CI, 2.10-9.06; P < .001) after controlling for systemic diseases (arterial hypertension, coronary heart disease, high cholesterol, and stroke). CONCLUSION: In the first study to compare XFG and POAG monitoring of the peripheral and central auditory pathway, it has been documented that XFG patients show a greater prevalence of retrocochlear pathology.
Asunto(s)
Audiometría de Tonos Puros , Potenciales Evocados Auditivos del Tronco Encefálico , Síndrome de Exfoliación/diagnóstico , Glaucoma de Ángulo Abierto/diagnóstico , Pérdida Auditiva Sensorineural/diagnóstico , Emisiones Otoacústicas Espontáneas , Enfermedades Retrococleares/diagnóstico , Anciano , Vías Auditivas/fisiopatología , Umbral Auditivo/fisiología , Tronco Encefálico/fisiopatología , Comorbilidad , Conducta Cooperativa , Estudios Transversales , Síndrome de Exfoliación/epidemiología , Síndrome de Exfoliación/fisiopatología , Femenino , Glaucoma de Ángulo Abierto/epidemiología , Glaucoma de Ángulo Abierto/fisiopatología , Pérdida Auditiva Sensorineural/epidemiología , Pérdida Auditiva Sensorineural/fisiopatología , Humanos , Comunicación Interdisciplinaria , Masculino , Tamizaje Masivo , Persona de Mediana Edad , Grupo de Atención al Paciente , Estudios Prospectivos , Enfermedades Retrococleares/epidemiología , Enfermedades Retrococleares/fisiopatologíaRESUMEN
OBJECTIVE: To investigate the hypothesis of cochlear and retrocochlear damage in scrub typhus, using evoked response audiometry. STUDY DESIGN: Prospective, randomised, case-control study. METHODS: The study included 25 patients with scrub typhus and 25 controls with other febrile illnesses not known to cause hearing loss. Controls were age- and sex-matched. All subjects underwent pure tone audiometry and evoked response audiometry before commencing treatment. RESULTS: Six patients presented with hearing loss, although a total of 23 patients had evidence of symmetrical high frequency loss on pure tone audiometry. Evoked response audiometry found significant prolongation of absolute latencies of wave I, III, V, and wave I-III interpeak latency. Two cases with normal hearing had increased interpeak latencies. These findings constitute level 3b evidence. CONCLUSION: Findings were suggestive of retrocochlear pathology in two cases with normal hearing. In other patients, high frequency hearing loss may have led to altered evoked response results. Although scrub typhus appears to cause middle ear cochlear and retrocochlear damage, the presence of such damage could not be fully confirmed by evoked response audiometry.
Asunto(s)
Audiometría de Respuesta Evocada/métodos , Enfermedades Retrococleares/diagnóstico , Tifus por Ácaros/diagnóstico , Adolescente , Adulto , Audiometría de Tonos Puros , Umbral Auditivo/fisiología , Estudios de Casos y Controles , Niño , Enfermedades Cocleares/complicaciones , Enfermedades Cocleares/diagnóstico , Enfermedades Cocleares/fisiopatología , Femenino , Pérdida Auditiva de Alta Frecuencia/diagnóstico , Pérdida Auditiva de Alta Frecuencia/etiología , Pérdida Auditiva Sensorineural/diagnóstico , Pérdida Auditiva Sensorineural/etiología , Humanos , Masculino , Estudios Prospectivos , Enfermedades Retrococleares/complicaciones , Enfermedades Retrococleares/fisiopatología , Tifus por Ácaros/complicaciones , Tifus por Ácaros/fisiopatología , Adulto JovenRESUMEN
The main purpose of this cross-sectional study was to investigate the presence of retrocochlear disease in a group of maintenance workers from a general hospital, who presents a history of noise exposure. Thirty one workers of three engineering sections with age range from 25 to 60 years and continuous noise exposure from 2 and 45 years, were examined. The evaluation included an audiometric occupational selection and auditory brainstem responses (ABR). ABR abnormalities were detected in seven patients (22.6%) and it was found latency increase of waves III (14.3%) and V (28.6%), and interpeak prolongation I-III (71.4%), III-V (28.6%) and I-V (85.7%). Among 35 ears with normal audition - right, left or both -, four (11,4%) ears presented retrocochlear disease. The high retrocochlear disease prevalence in workers exposed to noise lead us to suppose that this disturbance is more frequent than usually found; therefore it is underestimated in workers diagnostic evaluation. The presence of this kind of disturbance, even with the absence of audiometric alterations, suggests that ABR is more sensitive than the tonal audiometry for noise induced hearing loss investigation.
Asunto(s)
Potenciales Evocados Auditivos del Tronco Encefálico , Ruido en el Ambiente de Trabajo/efectos adversos , Enfermedades Profesionales/etiología , Enfermedades Profesionales/fisiopatología , Personal de Hospital , Enfermedades Retrococleares/etiología , Enfermedades Retrococleares/fisiopatología , Adulto , Estudios Transversales , Hospitales Generales , Humanos , Masculino , Persona de Mediana Edad , Exposición ProfesionalRESUMEN
O objetivo principal deste estudo seccional foi averiguar a presença de comprometimento auditivo retrococlear num grupo de trabalhadores de manutenção de um hospital de grande porte com histórico de exposição a ruído. Foram avaliados 31 trabalhadores de três setores da divisão de engenharia entre 25 e 60 anos e com exposição contínua a ruído entre 2 e 45 anos. O processo avaliativo contou com triagem audiométrica ocupacional e audiometria troncoencefálica (ATE). Foram detectadas anormalidades na ATE em sete pacientes (22,6 por cento), caracterizadas por aumento de latências de ondas III (14,3 por cento) e V (28,6 por cento); prolongamento dos interpicos I-III (71,4 por cento), III-V (28,6 por cento) e I-V (85,7 por cento). Das 35 orelhas com audição normal (três unilateralmente e 32 bilateralmente), quatro (11,4 por cento) apresentaram comprometimento retrococlear. A alta prevalência de comprometimento retrococlear no grupo induz supor que tal distúrbio seja mais frequente que o encontrado e esteja sendo subestimado na investigação diagnóstica desses trabalhadores. A ocorrência desses resultados sem a presença de alterações audiométricas sugere que a ATE seja mais sensível que a audiometria tonal na investigação de perda auditiva provocada por ruído, por isso sua utilização deva ser incentivada.
The main purpose of this cross-seccional study was to investigate the presence of retrocochlear disease in a group of maintenance workers from a general hospital, who presents a history of noise exposure. Thirty one workers of three engineering sections with age range from 25 to 60 years and continuous noise exposure from 2 and 45 years, were examined. The evaluation included an audiometric occupational selection and auditory brainstem responses (ABR). ABR abnormalities were detected in seven patients (22.6 percent) and it was found latency increase of waves III (14.3 percent) and V (28.6 percent), and interpeak prolongation I-III (71.4 percent), III-V (28.6 percent) and I-V (85.7 percent). Among 35 ears with normal audition right, left or both , four (11,4 percent) ears presented retrocochlear disease. The high retrocochlear disease prevalence in workers exposed to noise lead us to suppose that this disturbance is more frequent than usually found; therefore it is underestimated in workers diagnostic evaluation. The presence of this kind of disturbance, even with the absence of audiometric alterations, suggests that ABR is more sensitive than the tonal audiometry for noise induced hearing loss investigation.
Asunto(s)
Adulto , Humanos , Masculino , Persona de Mediana Edad , Potenciales Evocados Auditivos del Tronco Encefálico , Ruido en el Ambiente de Trabajo/efectos adversos , Enfermedades Profesionales/etiología , Enfermedades Profesionales/fisiopatología , Personal de Hospital , Enfermedades Retrococleares/etiología , Enfermedades Retrococleares/fisiopatología , Estudios Transversales , Hospitales Generales , Exposición ProfesionalRESUMEN
BACKGROUND: Allowing Medicare beneficiaries to self-refer to audiologists for evaluation of hearing loss has been advocated as a cost-effective service delivery model. Resistance to audiology direct access is based, in part, on the concern that audiologists might miss significant otologic conditions. PURPOSE: To evaluate the relative safety of audiology direct access by comparing the treatment plans of audiologists and otolaryngologists in a large group of Medicare-eligible patients seeking hearing evaluation. RESEARCH DESIGN: Retrospective chart review study comparing assessment and treatment plans developed by audiologists and otolaryngologists. STUDY SAMPLE: 1550 records comprising all Medicare eligible patients referred to the Audiology Section of the Mayo Clinic Florida in 2007 with a primary complaint of hearing impairment. DATA COLLECTION AND ANALYSIS: Assessment and treatment plans were compiled from the electronic medical record and placed in a secured database. Records of patients seen jointly by audiology and otolaryngology practitioners (Group 1: 352 cases) were reviewed by four blinded reviewers, two otolaryngologists and two audiologists, who judged whether the audiologist treatment plan, if followed, would have missed conditions identified and addressed in the otolaryngologist's treatment plan. Records of patients seen by audiology but not otolaryngology (Group 2: 1198 cases) were evaluated by a neurotologist who judged whether the patient should have seen an otolaryngologist based on the audiologist's documentation and test results. Additionally, the audiologist and reviewing neurotologist judgments about hearing asymmetry were compared to two mathematical measures of hearing asymmetry (Charing Cross and AAO-HNS [American Academy of Otolaryngology-Head and Neck Surgery] calculations). RESULTS: In the analysis of Group 1 records, the jury of four judges found no audiology discrepant treatment plans in over 95% of cases. In no case where a judge identified a discrepancy in treatment plans did the audiologist plan risk missing conditions associated with significant mortality or morbidity that were subsequently identified by the otolaryngologist. In the analysis of Group 2 records, the neurotologist judged that audiology services alone were all that was required in 78% of cases. An additional 9% of cases were referred for subsequent medical evaluation. The majority of remaining patients had hearing asymmetries. Some were evaluated by otolaryngology for hearing asymmetry in the past with no interval changes, and others were consistent with noise exposure history. In 0.33% of cases, unexplained hearing asymmetry was potentially missed by the audiologist. Audiologists and the neurotologist demonstrated comparable accuracy in identifying Charing Cross and AAO-HNS pure-tone asymmetries. CONCLUSIONS: Of study patients evaluated for hearing problems in the one-year period of this study, the majority (95%) ultimately required audiological services, and in most of these cases, audiological services were the only hearing health-care services that were needed. Audiologist treatment plans did not differ substantially from otolaryngologist plans for the same condition; there was no convincing evidence that audiologists missed significant symptoms of otologic disease; and there was strong evidence that audiologists referred to otolaryngology when appropriate. These findings are consistent with the premise that audiology direct access would not pose a safety risk to Medicare beneficiaries complaining of hearing impairment.