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Eur J Surg Oncol ; 44(3): 316-320, 2018 03.
Artículo en Inglés | MEDLINE | ID: mdl-28343732

RESUMEN

In recent years, the increasing numbers of small, apparently indolent thyroid cancers diagnosed in the world have encouraged investigators to consider non-intervention as an alternative to surgical management. In the following pages, the prospect of a non-intervention trial for thyroid cancer is considered with attention to the ethical issues that such a trial might raise. Such a non-intervention trial is analyzed relative to 7 ethical considerations: the social or scientific value of the research, the scientific validity of the trial, the necessity of fair selection of participants, a favorable risk-benefit ratio for trial participants, independent review of the trial, informed consent, and allowing the study participants to withdraw from the trial. A non-intervention trial for thyroid cancer is also considered relative to the central concept of equipoise.


Asunto(s)
Ensayos Clínicos como Asunto/ética , Ética en Investigación , Consentimiento Informado , Neoplasias de la Tiroides/patología , Espera Vigilante/ética , Progresión de la Enfermedad , Humanos , Selección de Paciente/ética , Pronóstico , Proyectos de Investigación , Medición de Riesgo
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