RESUMEN
BACKGROUND: Cutis marmorata telangiectatica congenita is a rare, cutaneous, reticulated, vascular anomaly characterized by congenital persistent cutis marmorata, telangiectasis, and phlebectasis. While systemic abnormalities frequently are associated with cutis marmorata telangiectatica congenita, ophthalmic abnormalities are quite rare and include congenital glaucoma and congenital, bilateral, total retinal detachments with secondary glaucoma. METHODS: The authors report a case of bilateral, tractional retinal detachments associated with peripheral fibrovascular proliferation simulating familial exudative vitreoretinopathy in a female child with cutis marmorata telangiectatica congenita. Molecular genetic analysis of the Norrie's disease gene was performed. RESULTS: After vitrectomy, the posterior poles of both eyes were reattached successfully. No abnormalities of the Norrie's disease gene were identified. CONCLUSIONS: Bilateral exudative vitreoretinopathy is a rare ophthalmic manifestation associated with cutis marmorata telangiectatica congenita.
Asunto(s)
Flebitis/congénito , Desprendimiento de Retina/complicaciones , Enfermedades de la Piel/congénito , Telangiectasia/congénito , Vitreorretinopatía Proliferativa/complicaciones , Preescolar , Femenino , Fondo de Ojo , Humanos , Flebitis/complicaciones , Flebitis/patología , Desprendimiento de Retina/patología , Desprendimiento de Retina/cirugía , Enfermedades de la Piel/complicaciones , Enfermedades de la Piel/patología , Telangiectasia/complicaciones , Telangiectasia/patología , Vitrectomía , Vitreorretinopatía Proliferativa/patología , Vitreorretinopatía Proliferativa/cirugíaRESUMEN
Gram-negative neonatal septicemia was diagnosed in a premature Standardbred colt. Clinical signs included lethargy, weakness, loss of suckle reflex, tachypnea, and injected mucous membranes. Sequelae included pneumonia, omphalophlebitis, septic arthritis, and osteomyelitis. Prepartum maternal uterine infection, premature delivery, abnormal parturition with premature fetal membrane separation, and failure of passive transfer of colostral immunoglobulins increased the foal's risk for developing sepsis. Treatment included administration of moxalactam disodium and cefadroxil. The clinical efficacy of cephalosporin antibiotics in the treatment of gram-negative sepsis is discussed.