Case report of a modified Meso-Rex bypass as a treatment technique for late-onset portal vein cavernous transformation with portal hypertension after adult deceased-donor liver transplantation.

RATIONALE: Portal vein thrombosis is a complication after liver transplantation and cavernous transformation of the portal vein (CTPV) is a result of portal vein thrombosis, with symptoms of portal hypertension revealed by an enhanced CT scan. Meso-Rex bypass is an artificial shunt connecting the left portal vein to the superior mesenteric vein and is mainly used for idiopathic cavernomas. This technique is also used for post-transplant portal vein thrombosis in pediatric patients thereby bypassing obstructed sites of the extrahepatic portal vein. Here we report about an adult patient who was treated by connecting the cystic part of the portal vein to the splenic vein instead of the superior mesenteric vein. PATIENTS CONCERN: An adult male patient with post-liver transplantation portal vein cavernous transformation suffered from hypersplenism and elevated hepatic enzymes. DIAGNOSIS: The last follow up revealed irregular and obvious hypersplenism, and splenomegaly had occurred, while an enhanced CT scan revealed serious esophagogastric varices and CTPV in addition to occluded right and common PV trunks. INTERVENTION: The patient was treated by connecting the cystic part of the portal vein to the splenic vein instead of the superior mesenteric vein. OUTCOME: After the operation, a satisfactory velocity was confirmed 1 month postoperatively and the shunt still remained patent at the 6-month postoperation follow-up. LESSONS: A Meso-Rex bypass intervention connecting the left portal vein to the splenic vein instead of the superior mesenteric vein after liver transplantation in an adult patient with right and common portal vein occlusions has been successfully performed as an alternative approach.

Histochemical study on hemangiomas in childhood.

The study was carried out on a material obtained by a biopsy from 18 children having different types of hemangiomas (capillary, cavernous and combined). Histochemical reactions were applied for the following enzymes: Succenatedehydrogenase (SDH), lactatdehydrogenase (LDH), cytochromoxidase, acid phosphatase, alkaline phosphatase and paraspecific esterases. Differently reduced activity of the succenatedehydrogenase and the cytochromoxidase in the endothelial cells and the pericytes was established. A reduced enzyme activity was observed also in a large part of the cases of acid phosphatase. The activity of the alkaline phosphatase and paraspecific esterases was greatly increased. Based on their observations the authors relate the hemangiomas to the tumour formations with a good prognosis.