Malignant fibrous histiocytoma in a patient presenting with urinary system symptoms

Summary Malignant fibrous histiocytoma is a rare tumor. It is most commonly seen in individuals between the fifth and seventh decades of life, in extremities, and less frequently in the retroperitoneum. Although its etiology is not clearly known, radiotherapy, chemical agents, previous history of surgery, trauma and fracture, and Hodgkin lymphoma have been blamed. Leiomyosarcoma, liposarcoma and rhabdomyosarcoma should be taken into account in differential diagnosis. It is seen on computed tomography as a mass lesion with irregular borders and density similar to that of the surrounding muscle tissue. Necrotic and hemorrhagic components in the mass are characterized as heterogeneous low density areas. Fluid-fluid levels can be detected by computed tomography and magnetic resonance imaging.

Malignant fibrous histiocytoma in a patient presenting with urinary system symptoms.

Malignant fibrous histiocytoma is a rare tumor. It is most commonly seen in individuals between the fifth and seventh decades of life, in extremities, and less frequently in the retroperitoneum. Although its etiology is not clearly known, radiotherapy, chemical agents, previous history of surgery, trauma and fracture, and Hodgkin lymphoma have been blamed. Leiomyosarcoma, liposarcoma and rhabdomyosarcoma should be taken into account in differential diagnosis. It is seen on computed tomography as a mass lesion with irregular borders and density similar to that of the surrounding muscle tissue. Necrotic and hemorrhagic components in the mass are characterized as heterogeneous low density areas. Fluid-fluid levels can be detected by computed tomography and magnetic resonance imaging.

Fibrohistiocitoma maligno cutáneo con metástasis satélites / Malígnant fibrous histiocytoma with satellite metastasis

El fibrohistiocitoma maligno es un tumor subcutáneo de larga evolución y localizado principalmente en extremidades. Se presenta el caso de una paciente de 77 años con una tumoracián nodular de superficie ulcerada con múltiples pápulas perilesionales en su pierna derecha. Se realizó la confirmación histopatológica y de inmunohistoquimica compatible con Fibrohistiacitoma maligno asociado a metástasis cutáneas satélites.

Malignant fibrous histiocytoma is a subcutaneous tumor of long evolution, more frequently located in the extremities. We present the case of a 77 year- old female with a nodular ulcerated tumor with multiple perilesional papules on her right lower leg. Histopathology and immunohistochemistry were consistent with cutaneous malignant fibrous histiocytoma associated to satellite metastasis.

Retalho de padrão axial toracodorsal para correção de defeito extenso após excisão de histiocitoma fibroso maligno em canino relato de caso / Axial pattern thoracodorsal flap for treatment of large defect after malignant fibrous histiocytoma resection in a dog - case report

Os retalhos de pele em padrão axial toracodorsal são utilizados em cães para reconstruções do membrotorácico que envolvam desde a região média até a distal do antebraço. Relata-se um caso de excisão de histiocitoma fibroso maligno e reconstituição cirúrgica por meio do retalho supracitado em membro torácico de canino. Foram observadas como complicações edema, infecção, drenagem de líquido transparente da extremidade distal do membro através da interface pele-enxerto, seromae necrose parcial na região do olécrano e distal do retalho. Contudo, a maior parte do flape apresentou adequada cicatrização no leito receptor e o aspecto cosmético foi considerado satisfatório. Aos 40 dias de pós-operatório o animal veio à óbito subitamente. Na necropsia, observou-se miosite necrossupurativa nos membros posteriores em consequência de trombos oriundos de feocromocitoma maligno originário da adrenal direita.AU

Thoracodorsal axial pattern skin grafts are used in dogs for forelimb reconstructions involving since middleup to distal forearm regions. This paper reports a case of malignant fibrous histiocytoma excision in canine forelimb and its surgical reconstruction using thoracodorsal flap. The complications observed are swelling, infection, drainage of clear fluid from the distal limb through the skin-graft interface, seroma and partial flap necrosis. However, most flap area provided adequate healing in the receptor site and its cosmetic appearance was satisfactory. The animal sudden died in the 40th postoperative day. The necropsy showed necrosuppurative myositis in the hind limbs as a result of thrombus originating from a right adrenal malignant pheochromocytoma.

Retalho de padrão axial toracodorsal para correção de defeito extenso após excisão de histiocitoma fibroso maligno em canino – relato de caso / Axial pattern thoracodorsal flap for treatment of large defect after malignant fibrous histiocytoma resection in a dog - case report

Os retalhos de pele em padrão axial toracodorsal são utilizados em cães para reconstruções do membrotorácico que envolvam desde a região média até a distal do antebraço. Relata-se um caso de excisão de histiocitoma fibroso maligno e reconstituição cirúrgica por meio do retalho supracitado em membro torácico de canino. Foram observadas como complicações edema, infecção, drenagem de líquido transparente da extremidade distal do membro através da interface pele-enxerto, seromae necrose parcial na região do olécrano e distal do retalho. Contudo, a maior parte do flape apresentou adequada cicatrização no leito receptor e o aspecto cosmético foi considerado satisfatório. Aos 40 dias de pós-operatório o animal veio à óbito subitamente. Na necropsia, observou-se miosite necrossupurativa nos membros posteriores em consequência de trombos oriundos de feocromocitoma maligno originário da adrenal direita.

Thoracodorsal axial pattern skin grafts are used in dogs for forelimb reconstructions involving since middleup to distal forearm regions. This paper reports a case of malignant fibrous histiocytoma excision in canine forelimb and its surgical reconstruction using thoracodorsal flap. The complications observed are swelling, infection, drainage of clear fluid from the distal limb through the skin-graft interface, seroma and partial flap necrosis. However, most flap area provided adequate healing in the receptor site and its cosmetic appearance was satisfactory. The animal sudden died in the 40th postoperative day. The necropsy showed necrosuppurative myositis in the hind limbs as a result of thrombus originating from a right adrenal malignant pheochromocytoma.

Early radiation-induced laryngeal malignant fibrous histiocytoma (MFH).

Postradiation sarcoma is a potential late sequela of ionising radiation and its frequency is rare. We present the case of a man with a radiation-induced malignant fibrous histiocytoma with a latent period of 20 months.