The Antibiotic Nail in the Treatment of Long Bone Infection: Technique and Results.

Antibiotic cement nails provide a useful and relatively simple technique to treat intramedullary osteomyelitis of the long bones. These devices provide stability as well as local, targeted antibiotics, which are both critical aspects of osteomyelitis management. Additionally, the use of a threaded core is a critical component of successful cement nail assembly. With adherence to the simple principles outlined in this review, surgeons can expect reliably good results using these drug-delivery implants.

A new murine model to study musculoskeletal tuberculosis (short communication).

Musculoskeletal tuberculosis (TB) is a severe extrapulmonary manifestation of chronic Mycobacterium (M.) tuberculosis infection. Considering increasing incidence, multi-drug resistance and associated treatment difficulties, more preclinical research is needed. In this study we developed a murine model for musculoskeletal TB. Mice, intranasally infected with M. tuberculosis, were sacrificed after ten months. Mycobacterial growth was detected in lung and femur homogenates. Ziehl-Neelsen staining of paraffin-embedded femurs showed acid-fast rods in the myelum and Magnetic Resonance Imaging demonstrated osteomyelitis and macronodular tuberculomas. This new murine model of musculoskeletal TB might be of value to further investigate immunologic and radiologic responses.

Sífilis congenita presentación de un caso clínico radiológico / Congenital syphilis radiological presentation of a clinical case

La sífilis congénita tiene origen en la infección materna y se debe a la transmisión que sufre el feto por vía transplacentaria durante el embarazo. En paises subdesarrollados se puede mencionar como factor de riesgo la ausencia de un diagnóstico precoz en los controles prenatales y la poca información sobre todo en las madres adolescentes hacia esta enfermedad, la misma que avanza hacia la muerte in útero del feto, o al nacimiento con múltiples alteraciones del recien nacido. Se presenta el caso de un neonato cuya madre infectada no recibio tratamiento y posterior al nacimiento el neonato presentó clínica significativa por lo que se le realizaron una serie de exámenes, dentro de los que destacan los radiológicos en huesos largos, donde se advierten alteraciones típicas de esta enfermedad.

Congenital syphilis originates by maternal infection and is due to the transplacental transmission which the fetus suffers during pregnancy. In underdeveloped countries, the absence of an early diagnostic test during prenatal care has to be mentioned as a risk factor as well as the poor information on this disease that exists among mothers, especially teenage mothers. Due to these facts the progression of the disease frequently leads to death in uterus of the fetus or to multiple birth defects when the baby is born.We present the case of a newborn baby whose infected mother was not treated, and who after birth presented important clinical signs due to which a series of tests were carried out among which the radiology of the long bones stands out where the typical alterations of the disease are seen.