Asunto(s)
Antídotos/uso terapéutico , Artefactos , Hematuria , Hidroxocobalamina/uso terapéutico , Traumatismo Múltiple/orina , Urinálisis , Antídotos/farmacocinética , Intoxicación por Monóxido de Carbono/etiología , Intoxicación por Monóxido de Carbono/orina , Traumatismos Craneocerebrales/complicaciones , Traumatismos Craneocerebrales/orina , Incendios , Piromanía , Hematuria/orina , Humanos , Cianuro de Hidrógeno/envenenamiento , Hidroxocobalamina/farmacocinética , Hidroxocobalamina/orina , Masculino , Persona de Mediana Edad , Traumatismo Múltiple/complicaciones , Lesión por Inhalación de Humo/tratamiento farmacológico , Lesión por Inhalación de Humo/orina , Intento de Suicidio , Heridas por Arma de Fuego/orinaAsunto(s)
Antipsicóticos/envenenamiento , Barbitúricos/envenenamiento , Benzodiazepinas/envenenamiento , Intoxicación por Monóxido de Carbono/orina , Ácido Hidroxiindolacético/orina , Ácido Vanilmandélico/orina , Enfermedad Aguda , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , FenotiazinasRESUMEN
In preliminary experiments it had been shown that the total catecholamines in the urine of rats collected during 5 hrs after stimulation of diuresis with 50 ml tap water/kg body weight per os were not changed significantly following a 3-week training in individual metabolic cages, a short pressing of the animals against the laboratory table, a single i. p. injection of 2 ml sodium chloride solution (145 mmol/l)/kg body weight, or a single s. c. injection of 40 ml air per animal. The excretion was increased after puncture of the retroorbital plexus and after exposure to cold (+5 degrees C) during the 5 hrs. Carbon monoxide poisoning produces an inhibition of diuresis. Therefore, to study the effect of carbon monoxide intoxications on urinary catecholamine excretion we administered 25 ml tap water/kg additionally. Single s. c. injection of 7.2 mmol CO/kg body weight (53% COHb) induced a significant increase of urinary catecholamines. Due to repeated injections of the same CO dose a gradual disappearance of this effect was seen. After 4 weeks the differences to controls are negligible.