RESUMEN
Experiments on 172 Wistar rats modeled CCl4-hepatitis in transitory phases of about-annual cycle. In the autumn phase the animals with toxic hepatitis demonstrated poor normalization of biochemical parameters while the efficacy of physiotherapy (sapropel combined with magnetic field) was very high. In spring, normalization of the biochemical parameters was very high while the above physiotherapeutic complex was low effective.
Asunto(s)
Intoxicación por Tetracloruro de Carbono/terapia , Enfermedad Hepática Inducida por Sustancias y Drogas/terapia , Hepatitis Animal/terapia , Modalidades de Fisioterapia , Estaciones del Año , Animales , Benzopiranos/uso terapéutico , Intoxicación por Tetracloruro de Carbono/tratamiento farmacológico , Intoxicación por Tetracloruro de Carbono/radioterapia , Enfermedad Hepática Inducida por Sustancias y Drogas/tratamiento farmacológico , Enfermedad Hepática Inducida por Sustancias y Drogas/radioterapia , Campos Electromagnéticos , Hepatitis Animal/tratamiento farmacológico , Hepatitis Animal/radioterapia , Sustancias Húmicas , Hígado/fisiopatología , Masculino , Ratas , Ratas WistarRESUMEN
Red laser light (lambda = 633 nm) in a dose of 9.5 mJ/cm2 defends quail's embryo from X-ray irradiation (8.5 Gr). It is expressed in the 1.9 times decrease of embryo mortality on early term of incubation and 1.6 times increase of hatch in a group of embryos, which were affected by X-rays and laser radiation compared with an embryo, irradiated only by X-rays. Repeated laser irradiation of adult quails (dose 21 J) after CCl4-intoxication led to normalization of hydroxylation and antioxidant systems functions.
Asunto(s)
Antioxidantes/metabolismo , Intoxicación por Tetracloruro de Carbono/radioterapia , Coturnix/metabolismo , Rayos gamma , Terapia por Láser , Hígado , Animales , Intoxicación por Tetracloruro de Carbono/sangre , Intoxicación por Tetracloruro de Carbono/metabolismo , Coturnix/embriología , Embrión no Mamífero/efectos de la radiación , Femenino , Radicales Libres/metabolismo , Hidroxilación , Peróxidos Lipídicos/metabolismo , Hígado/efectos de los fármacos , Hígado/metabolismo , Hígado/efectos de la radiación , MasculinoRESUMEN
The optimal schedule of the preventive and therapeutical effect of helium-neon laser on the acute toxic hepatitis induced in rats by CCl4 is established. The laser dose of 5-10 mVt/cm2 for 5-10 min prevents the toxic hepatitis while therapeutical use of 7 to 10 such schedules reduces the intensity of the protein and fat degeneration, parenchymal necrosis and inflammatory infiltration.
