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1.
JAMA Dermatol ; 149(11): 1289-94, 2013 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-24048361

RESUMEN

IMPORTANCE: Determining Fitzpatrick skin phototypes (FST) allows physicians to assess a person's risk of developing sunburn and, by extension, the need for sun protection to prevent the development of skin cancer. Reflectance spectrophotometry objectively measures the melanin index and can assist in determining the accuracy of self-report of FST compared with dermatologist-determined FST. OBJECTIVES: To assess whether self-reported or dermatologist-determined FST is more accurate in identifying a participant's FST for FST I through VI and to assess the relevance of the burning and tanning measures for a range of skin types among ethnically diverse participants. DESIGN AND SETTING: A convenience sample of participants in an observational study from June 2, 2010, through December 15, 2010, at an ambulatory academic dermatologic practice and employee health center in an urban city. PARTICIPANTS: Participants, staff, and students of Northwestern University, who self-identified as being non-Hispanic white, Hispanic or Latino, Asian or Pacific Islander, or black. MAIN OUTCOMES AND MEASURES: Melanin index as measured with reflectance spectrophotometry compared with dermatologist- and participant-determined FST. RESULTS: Forty-two percent (114 of 270) of the participants' responses to the burning and tanning questions could not be classified using standard FST definitions. The spectrophotometry measurements for dermatologist-determined FST were significantly different for FST III and IV (P < .001) and FST IV and V (P < .001). The spectrophotometry measurements for participant-determined FST were significantly different for FST III and IV (P < .001) but not for FST IV and V (P = .90). Participant responses to burning and the dermatologist-determined FST were significantly correlated (Spearman ρ, 0.764; P < .001). Participant responses to tanning and the dermatologist-determined FST were not significantly correlated (Spearman ρ, 0.089; P = .15). Spectrophotometry measurements assessing FST were statistically significantly different for FST III through VI (P < .001). CONCLUSIONS AND RELEVANCE: Dermatologist-determined FST is more accurate than self-report for FST III through VI. Rephrasing the questions using specific descriptors that have meaning to people with skin of color, such as skin irritation, tenderness, itching, or skin becoming darker, may allow physicians to more accurately assign a skin phototype and, by inference, assess the risk of these participants developing skin cancer. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT01124513.


Asunto(s)
Melaninas/química , Índice de Severidad de la Enfermedad , Pruebas de Irritación de la Piel/clasificación , Pigmentación de la Piel/efectos de la radiación , Luz Solar/efectos adversos , Adulto , Anciano , Anciano de 80 o más Años , Etnicidad , Humanos , Persona de Mediana Edad , Valor Predictivo de las Pruebas , Reproducibilidad de los Resultados , Factores de Riesgo , Autoinforme , Neoplasias Cutáneas/prevención & control , Espectrofotometría , Adulto Joven
3.
Actas dermo-sifiliogr. (Ed. impr.) ; 102(8): 563-571, oct. 2011.
Artículo en Español | IBECS | ID: ibc-92559

RESUMEN

Los estudios epidemiológicos ponen de manifiesto que cada vez son más las personas que dicen poseer una piel sensible, presumiéndose una prevalencia del 50% en la población europea. Se trata de una condición cutánea de hiperreactividad cuya manifestación depende de gran variedad de factores y cuya patogénesis no es del todo conocida, aunque diferentes estudios señalan un origen biofísico para este desorden. El diagnóstico objetivo de piel sensible es difícil, ya que la mayoría de los síntomas que presentan los pacientes son subjetivos. Además, no existen pruebas diagnósticas realmente eficaces y con un fuerte componente predictivo, pues la sensibilidad de la piel varía mucho de unas personas a otras. Por otra parte existen numerosas variaciones entre los compuestos que desencadenan respuestas del tipo de piel sensible. Las repercusiones sobre la calidad de vida son importantes y frecuentemente se acompañan de sintomatología psiquiátrica, por lo que el médico dermatólogo debe explorar este campo en la anamnesis. En el tratamiento de esta condición se hace imprescindible la colaboración del paciente y altas dosis de tenacidad por parte del médico (AU)


Epidemiologic studies indicate that ever larger numbers of people report having sensitive skin, for which a European prevalence of 50% is estimated. Sensitive skin is characterized by hyperreactivity, with manifestations varying in relation to many factors. The pathogenesis of this disorder is poorly understood, although studies point to a biophysical mechanism. Objective diagnosis of sensitive skin is difficult, as information comes mainly from the patient's report of symptoms in the absence of effective, strongly predictive tests because of great interindividual variability in skin sensitivity. Substances that trigger a reaction in hypersensitive skin also vary greatly. The impact of this syndrome on quality of life is considerable and patients often present psychiatric symptoms; therefore, dermatologists should explore this possibility when taking a patient's history. Patient cooperation and physician persistence are both essential for treating sensitive skin (AU)


Asunto(s)
Humanos , Masculino , Femenino , Dermatitis Irritante/etiología , Dermatitis Irritante/fisiopatología , Dermatitis Irritante/terapia , Irritantes/efectos adversos , Prurito/inducido químicamente , Enfermedades de la Piel , Hipersensibilidad , Hipersensibilidad/terapia , Dermatitis Irritante/clasificación , Pruebas de Irritación de la Piel/clasificación , Pruebas de Irritación de la Piel/métodos , Cosméticos/efectos adversos , Jabones/efectos adversos , Higroscópicos/uso terapéutico , Dermatitis Irritante/prevención & control , Salicilato de Sodio/uso terapéutico , Prurito Vulvar/inducido químicamente , Dermatitis Atópica/complicaciones
4.
Contact Dermatitis ; 65(2): 65-75, 2011 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-21668861

RESUMEN

Visual assessment of skin reactions has long been used to evaluate the safety of chemicals and preparations that contact the skin, and to meet regulatory requirements. This article reviews the history of visual grading scales, and the results of investigations into the reliability of the method. Some examples are provided to illustrate the diverse array of protocols that use visual scoring to evaluate skin irritation. Furthermore, as bioengineering methods are developed that can quantitate certain aspects of skin irritant and sensitization reactions, it is important to consider whether such measures should supplement or replace visual assessment. Examples of investigations comparing the outcomes of studies that use visual scoring and those that use bioengineering methods are discussed. These examples provide little evidence that bioengineering measures provide an improvement in overall quality in comparison with current testing methods that rely on visual assessment. In addition, such measuring techniques can add considerably to the complexity of testing protocols. When benefits and cost are weighed in the balance, the visual assessment scales popularized by Draize and others remain an effective, practical method of evaluation.


Asunto(s)
Dermatitis Irritante/diagnóstico , Pruebas del Parche/historia , Pruebas del Parche/métodos , Pruebas de Irritación de la Piel/clasificación , Pruebas de Irritación de la Piel/métodos , Colorimetría/clasificación , Colorimetría/métodos , Historia del Siglo XX , Historia del Siglo XXI , Humanos , Pruebas del Parche/clasificación , Reproducibilidad de los Resultados , Sensibilidad y Especificidad
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