Complications of Flat Bed Rest After Incidental Durotomy.

STUDY DESIGN: Retrospective case series. OBJECTIVE: To determine whether bed rest is a risk factor for specific medical complications. SUMMARY OF BACKGROUND DATA: Flat bed rest after incidental durotomy is commonly used to reduce the risk of CSF leakage and associated complications. METHODS: Retrospective case series of consecutive patients after lumbar laminectomy were identified. Medical records were reviewed for duration of bed rest and complications (pulmonary, wound, neurological, gastrointestinal, and urinary) in the chart notes, repair methods, subfascial drain placement, consultant notes, imaging reports, and discharge summaries. Patients were compared with duration of bed rest >24 hours versus duration of bed rest ≤24 hours. The incidence of complications was compared between groups using the Fisher exact test. RESULTS: There were a total of 42 patients with incidental durotomy. There were 18 patients in the bed rest ≤24 hours group and 24 patients in the bed rest >24 hours group. Comparing the bed rest ≤24 hours to bed rest >24 hours patients, there was no statistically significant difference in the incidence of postdurotomy-related neurological complications, wound complications, and need for revision surgery. There was a statistically significant decrease in the incidence of total medical complications in the ≤24-hour group (0% vs. 50%, P=0.0003). CONCLUSION: There was an increased incidence of medical complications in the bed rest group >24 hours. Flat bed rest after modern dural repair method may not be a necessity in all cases and may be associated with a higher incidence of medical complications.

Efficacy and safety of a porcine collagen sponge for cranial neurosurgery: a prospective case-control study.

OBJECTIVE: The use of dural grafts is very useful when primary dural closure cannot be achieved. Our primary objective was to study the incidence of postoperative cerebrospinal fluid leak, including fistula and pseudomeningocele, and postoperative infection by comparing autologous material and a new collagen graft. MATERIALS AND METHODS: A prospective nonrandomized study with a new collagen-based product derived from porcine cells (Peridry) was performed. It was used for dural replacement in 50 patients who underwent a variety of neurosurgical procedures requiring the use of a dural graft. These results were compared with a control group of 50 patients who were treated with autologous duraplasty material. The follow-up period was 3 months. RESULTS: Postoperative overall cerebrospinal fluid fistula occurred in 6% of both groups. No patient in the collagen group developed any sort of infection. One patient in the control developed osteomyelitis in the bone flap. CONCLUSION: The new collagen-based product derived from porcine cells (Peridry), compared with an autologous tissue, is safe, effective, easy to use, as well as time saving in cranial neurosurgery.

Craniopharyngioma.

Craniopharyngiomas are rare epithelial tumors arising along the path of the craniopharyngeal duct; therefore, they occur in the sellar or suprasellar regions. These tumors commonly lead to neurologic, endocrinological, or visual symptoms. Radical surgery is the treatment of choice in craniopharyngiomas. The transnasal/transsphenoidal endoscopic approach offers the possibility of removing the tumor without retracting brain and optic pathways, with good results. The rate of cerebrospinal fluid fistula has improved due to the use of vascularized mucosal flaps for cranial base reconstruction.

Pituitary tumors: our experience in the prevention of postoperative cerebrospinal fluid leaks after transsphenoidal surgery.

The objective was to analyze the management of intraoperative CSF leaks in transsphenoidal surgeries to prevent postoperative cerebrospinal fluid (CSF) leaks. Sixty-three pituitary tumors were operated by transnasal approach. In presence of arachnoidal opening, a fat graft was placed into the sellar cavity, followed by collagen sponge layer and fibrin glue. The sphenoid sinus was also packed with fat graft and collagen sponge. An external CSF lumbar drainage was kept for 2-4 days. The variables analyzed were: intraoperative and postoperative CSF leaks, procedures, and related complications. The overall incidence of postoperative CSF leak was 1.5%. Twenty patients (31.7%) had intraoperative arachnoidal opening, 5% of whom had postoperative CSF leak. There were no reoperations because of CSF leak, and no secondary intrasellar arachnoidoceles. Mean follow-up was 3.6 years. The preventive treatment had good results and there were no complications related to the intervention strategy, encouraging us to continue performing this simple, effective, and inexpensive procedure.

Sellar floor reconstruction after transsphenoidal surgery using fibrin glue without grafting or implants: technical note.

BACKGROUND: Different techniques have already been described for reconstructing the sellar floor after transsphenoidal (TS) procedures. This paper reports on the use of fibrin glue alone without grafting or the use of implants in the reconstruction of the sellar floor after TS. METHODS: Five hundred sixty-seven patients who submitted to TS for pituitary and sellar region tumors were studied. No intraoperative cerebrospinal fluid (CSF) leak occurred in 503 patients (group 1); in the remaining 64 patients (group 2), intraoperative CSF leak was noted. In group 1 patients, closure of the sellar floor consisted of packing the surgical bed with hemostatic material only. When CSF leak was noted, the surgical bed was covered with a layer of hemostatic material and the intrasellar space was filled up with fibrin glue. An additional layer of hemostatic material was added at the topography of the preexisting sellar floor, and a second amount of fibrin glue was applied over it. At the end of surgery, a continuous lumbar CSF drainage system was installed in group 2 patients and kept for 5 days. Prophylactic antibiotics were administered during this period. RESULTS: We did not observe delayed CSF leak, meningitis, or visual loss in group 1 patients. In group 2, 2 patients presented with complications: 1 patient got meningitis but no overt CSF leak, and the other disclosed a delayed postoperative leak treated by reoperation. DISCUSSION: Our results showed that closure of the sellar floor with hemostatic material and fibrin glue without grafting or the use of implants is a safe and efficient method to prevent postoperative complications after TS. Generally speaking, there is no need for grafting or the use of implants at the end of TS.