Asunto(s)
Dermatología/historia , Síndrome de Behçet/historia , Dermatólogos , Francia , Historia del Siglo XX , Humanos , Filatelia , TurquíaRESUMEN
Hulusi Behçet (1889-1948) was an internationally oriented Turkish dermatologist. He was closely involved in establishing the Istanbul Faculty of Medicine, where he later became a professor. In addition, Behçet was a scientist and an editor of the German professional journal, Dermatologische Wochenschrift. In articles published in this journal, he had written about 3 patients who suffered from an inexplicable triad of symptoms: eye problems, oral en genital ulcers. This oculo-urogenital syndrome now bears his name: 'Behçet's disease'.
Asunto(s)
Síndrome de Behçet/historia , Dermatología/historia , Historia del Siglo XIX , Historia del Siglo XX , Humanos , TurquíaAsunto(s)
Síndrome de Behçet/historia , Dermatología/historia , Epónimos , Historia del Siglo XX , Humanos , TurquíaRESUMEN
BACKGROUND: The aim is to inform authors, investigators, and journal editors about the evolution and progression of Behçet symptoms or findings chronologically in evidence-based historical articles since Hippocratic writings to bring physicians with different areas of interest to a consensus and thus address the significance of consistency in the eponym "Behçet" among authors interested in Behçet's disease care and research, as science does not accept a "naming dilemma". MATERIAL/METHODS: The historical progression of Behçet's disease is divided into three periods, namely pre-Behçet, Behçet, and post-Behçet. RESULTS: Although similar symptoms and clinical findings were reported in Hippocratic writings, a clear description of the "Triple Symptom Complex" consisting of the "Classical Triad" that indicates a new syndrome, was not presented until the important publications of Dr. Hulusi Behçet. CONCLUSIONS: This article will answer the needs and questions of authors and journal editors who are in a dilemma regarding the eponym. Therefore, researchers should strongly avoid changing the name of an old disorder well known since 1941 as "Behçet's disease" by not only every physician who supervises Behçet patients throughout the world, but also medical students and even the public. This would otherwise lead to needless chaos among journal editors, authors, and Behçet patients, who already have difficulty in defining their illness with high morbidity from blinding ocular disease or mortality from vascular, pulmonary, and neurological involvement.
Asunto(s)
Síndrome de Behçet/diagnóstico , Síndrome de Behçet/historia , Progresión de la Enfermedad , Epónimos , Femenino , Historia del Siglo XIX , Historia del Siglo XX , Historia Antigua , Humanos , Masculino , Investigación/historia , TurquíaRESUMEN
Behçet's disease is a systemic vasculitis affecting small and large vessels (arteries, veins, veinules), characterized by recurrent oral ulcerations, genital ulcerations, inflammation of the eye and skin lesions. It can also involve articulations, central nervous system and gastro-intestinal tract. The etiology of this disease is still unknown, but the most largely discussed hypothesis is that of an important inflammatory response triggered by an infectious agent in a genetically susceptible host. The diagnostic is a based on clinical elements, because no specific diagnostic test exists. The treatment of Behçet's disease is depending on the clinical involvement and has been enlarged in recent years by TNF-alpha-blockers which constitute undoubtedly an important progress in the management of this complex disease.
Asunto(s)
Síndrome de Behçet/diagnóstico , Síndrome de Behçet/terapia , Síndrome de Behçet/epidemiología , Síndrome de Behçet/historia , Diagnóstico Diferencial , Historia del Siglo XX , Historia Antigua , Humanos , Factor de Necrosis Tumoral alfa/antagonistas & inhibidoresRESUMEN
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Vasculitis/clasificación , Vasculitis/historia , Poliarteritis Nudosa/epidemiología , Poliarteritis Nudosa/historia , Dermatología/historia , Tromboangitis Obliterante/complicaciones , Tromboangitis Obliterante/historia , Granulomatosis con Poliangitis/historia , Vasculitis por IgA/historia , Arteritis de Takayasu/historia , Nefritis/complicaciones , Tromboangitis Obliterante/epidemiología , Tromboangitis Obliterante/prevención & control , Síndrome de Behçet/historiaRESUMEN
A doença de Behçet consiste em uma vasculite sistêmica que acomete veias, artérias e capilares, mas predominantemente pequenos vasos. Raramente há o envolvimento de veias e artérias de médio e grande calibre, sendo as artérias menos acometidas que as veias. No presente trabalho, os autores apresentam um relato de caso de aneurisma da artéria poplítea em um paciente com a doença de Behçet descompensada. Discutem-se os aspectos clínicos e radiológicos e o manejo cirúrgico dos pacientes com essa doença inflamatória sistêmica que apresentam peculiaridades importantes.
Behçet's disease consists of a systemic vasculitis that affects veins, arteries and capillaries, but predominantly small vessels. Veins and medium- and large-caliber arteries are rarely involved; however, arteries are less involved than veins. In this paper the authors present a case of popliteal artery aneurysm in a patient with decompensated Behçet's disease. We discuss clinical, radiological and surgical aspects of patients with this inflammatory systemic disease who present important peculiarities.
Asunto(s)
Masculino , Persona de Mediana Edad , Humanos , Aneurisma/complicaciones , Aneurisma/diagnóstico , Arteria Poplítea/anomalías , Arteria Poplítea/lesiones , Síndrome de Behçet/complicaciones , Síndrome de Behçet/diagnóstico , Síndrome de Behçet/historiaRESUMEN
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