RESUMEN
Necrotising sialometaplasia (NS) is a rare condition, with a limited scientific evidence base regarding its aetiology and pathophysiology. Diagnosing NS demands extensive investigatory tests. Their accuracy is vital in order to exclude oral malignancy and prevent unwarranted, invasive management.Within Birmingham Dental Hospital, a 22-year-old, South Asian woman presented with generalised pain from the lower right third molar extending to involve the palate, to which the patient's general medical practitioner previously attributed to a viral upper respiratory infection. Clinical examination revealed bilateral erythematous: non-ulcerated, palatal swellings (10 mm x 5 mm) at the greater palatine foramina. Following extensive investigations, the challenging definitive diagnoses of two distinct pathologies were made: non-ulcerative NS and pericoronitis.This case report describes the successful diagnosis and management of non-ulcerating NS, an 'atypical' presentation of a rare condition, that was confounded by a simultaneous episode of pericoronitis - a presentation not previously documented within scientific literature.
Asunto(s)
Pericoronitis , Sialometaplasia Necrotizante , Femenino , Humanos , Adulto Joven , Pueblo Asiatico , Pericoronitis/complicaciones , Pericoronitis/diagnóstico , Pericoronitis/terapia , Sialometaplasia Necrotizante/complicaciones , Sialometaplasia Necrotizante/diagnóstico , Sialometaplasia Necrotizante/terapia , Personas del Sur de AsiaAsunto(s)
Sialometaplasia Necrotizante/diagnóstico , Biopsia , Carcinoma de Células Escamosas/complicaciones , Carcinoma de Células Escamosas/terapia , Quimioradioterapia , Diagnóstico Diferencial , Femenino , Humanos , Persona de Mediana Edad , Neoplasias Palatinas/diagnóstico , Sialometaplasia Necrotizante/complicaciones , Sialometaplasia Necrotizante/diagnóstico por imagen , Sialometaplasia Necrotizante/patología , Neoplasias Gástricas/complicaciones , Neoplasias Gástricas/terapia , Tomografía Computarizada por Rayos XRESUMEN
We report a rare case of necrotizing sialometaplasia of the right lateral nasopharynx with extension into the right parapharyngeal space in a 39-year-old man. Since this is a self-limiting condition, the patient began to improve spontaneously over the next few weeks, and he experienced a complete recovery. Necrotizing sialometaplasia is an uncommon condition that is known to involve the palate; nasopharyngeal involvement is very rare, and to the best of our knowledge, extension into the parapharyngeal area has not been previously reported in the English-language literature. This condition poses a diagnostic dilemma because it closely mimics a malignancy, and failure to recognize it can result in unnecessary investigations and extensive surgery. We also review the literature on necrotizing sialometaplasia of the oropharyngeal area.
Asunto(s)
Enfermedades Linfáticas/patología , Enfermedades Nasofaríngeas/diagnóstico , Sialometaplasia Necrotizante/diagnóstico , Adulto , Dolor de Oído/etiología , Humanos , Enfermedades Linfáticas/etiología , Masculino , Enfermedades Nasofaríngeas/complicaciones , Dolor/etiología , Faringitis/etiología , Remisión Espontánea , Sialometaplasia Necrotizante/complicaciones , Trismo/etiologíaRESUMEN
INTRODUCTION: Necrotizing sialometoplasia (NS) is a disease in which the clinical and sometimes even histological features can be confused with those of a malignant tumor, but which is in fact a self-limited inflammatory lesion of the salivary glands. CASE REPORT: The authors present a case study of a 43-year-old female patient who came to the ENT Emergency Department with a painful ulcerated lesion of the hard palate. The lesion was 8 days old and had appeared after an abdominoplasty. Given the clinical need to rule out a malignant neoplasm, a biopsy was performed: the histological result was NS. DISCUSSION/CONCLUSION: The authors make a literature review and stress the importance of differentiating between NS and salivary gland neoplasia. Histology is essential in case of ulcerated neoformation of the oral cavity, to adapt treatment, avoiding unsuitable approaches.
Asunto(s)
Sialometaplasia Necrotizante/diagnóstico , Abdominoplastia/efectos adversos , Adulto , Biopsia , Índice de Masa Corporal , Diabetes Mellitus Tipo 2/complicaciones , Diagnóstico Diferencial , Femenino , Estudios de Seguimiento , Gastroplastia , Humanos , Intubación Intratraqueal/efectos adversos , Obesidad Mórbida/complicaciones , Sialometaplasia Necrotizante/complicaciones , Sialometaplasia Necrotizante/etiología , Sialometaplasia Necrotizante/patologíaRESUMEN
The first case reported in the literature of a rare disease called necrotizing scialometaplasia (NS), dates back to 1973 when Abrams et al. described the main histological features of this disease. In this article we describe the rare clinical case of a young woman came to our observation for a double ulcer in the middle portion of the hard palate, aching, that histological examination showed compatible with a diagnosis of NS and preceded his appearance a haemorrhagic conjunctival suffusion left. We have provided a complete description of all the investigations in which the patient underwent and its treatment. We have also outlined the major etiological hypotheses of SN, histological features that point to a correct diagnosis, clinical features and prognostic and finally we reflected on the rare and interesting overlap in clinical manifestations palatal and conjunctival those trying to find a possible explanation.
Asunto(s)
Enfermedades de la Conjuntiva/diagnóstico , Hemorragia del Ojo/diagnóstico , Sialometaplasia Necrotizante/diagnóstico , Adulto , Biopsia , Enfermedades de la Conjuntiva/complicaciones , Hemorragia del Ojo/complicaciones , Femenino , Humanos , Úlceras Bucales/etiología , Glándulas Salivales Menores/patología , Sialometaplasia Necrotizante/complicacionesRESUMEN
A very rare case of necrotizing sialometaplasia of the parotid gland associated with angiocentric T-cell lymphoma was described. A 66-year-old male had left neck and pharyngeal masses and biopsy specimen showed a monotonous proliferation of atypical lymphoid cells with massive necrosis in the parotid gland. Angiocentric pattern or vascular invasion by the lymphoid cells was observed and the involved parotid gland exhibited squamous metaplasia of the ducts and acini; necrotizing sialometaplasia. Immunohistochemical analysis revealed a cytotoxic T-cell phenotype of the lymphoid cells (CD3+, CD4-, CD5+, CD8+, CD56-, Granzyme B+, TIA-1+, Perforin-) but in situ hybridization showed no relation to Epstein-Barr virus. Although necrotizing sialometaplasia is relatively rare in the parotid gland, angiocentric T-cell lymphoma should be considered for a causative condition of necrotizing sialometaplasia.
Asunto(s)
Linfoma de Células T/patología , Neovascularización Patológica/patología , Glándula Parótida/patología , Sialometaplasia Necrotizante/patología , Anciano , Biomarcadores de Tumor , Humanos , Inmunohistoquímica , Linfoma de Células T/complicaciones , Masculino , Neovascularización Patológica/complicaciones , Sialometaplasia Necrotizante/complicacionesAsunto(s)
Bronquios/patología , Neoplasias de los Bronquios/patología , Histiocitoma Fibroso Benigno/patología , Mucosa Respiratoria/patología , Sialometaplasia Necrotizante/diagnóstico , Neoplasias de los Bronquios/complicaciones , Neoplasias de los Bronquios/cirugía , Histiocitoma Fibroso Benigno/complicaciones , Histiocitoma Fibroso Benigno/cirugía , Humanos , Hallazgos Incidentales , Masculino , Persona de Mediana Edad , Neumonectomía , Sialometaplasia Necrotizante/complicacionesAsunto(s)
Neoplasias del Seno Maxilar/complicaciones , Pólipos/complicaciones , Sialometaplasia Necrotizante/complicaciones , Diagnóstico Diferencial , Humanos , Masculino , Neoplasias del Seno Maxilar/diagnóstico , Persona de Mediana Edad , Pólipos/diagnóstico , Sialometaplasia Necrotizante/diagnósticoRESUMEN
One case of Abrikossof's tumor of the tongue associated with sialometaplasia is reported. The autors discuss the histogenesis of the granular-cell tumor. Actually, most of the autors agree to acknowledge a neurogene origin of the tumor: the typical granular cell of the myoblastoma, first described by Abrikossof, would originate from the schwann's cell, due to the ultrastructural morphological likeness of these cells with the phagocytic form of the schwann's cell.