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1.
BMJ Open Qual ; 13(2)2024 Apr 24.
Artículo en Inglés | MEDLINE | ID: mdl-38663928

RESUMEN

INTRODUCTION: At Sandwell General Hospital, there was no risk stratification tool or pathway for head injury (HI) patients presenting to the emergency department (ED). This resulted in significant delays in the assessment of HI patients, compromising patient safety and quality of care. AIMS: To employ quality improvement methodology to design an effective adult HI pathway that: ensured >90% of high-risk HI patients being assessed by ED clinicians within 15 min of arrival, reduce CT turnaround times, and aiming to keep the final decision making <4 hours. METHODS: SWOT analysis was performed; driver diagrams were used to set out the aims and objectives. Plan-Do-Study-Act cycle was used to facilitate the change and monitor the outcomes. Process map was designed to identify the areas for improvement. A new HI pathway was introduced, imaging and transporting the patients was modified, and early decisions were made to meet the standards. RESULTS: Data were collected and monitored following the interventions. The new pathway improved the proportion of patients assessed by the ED doctors within 15 min from 31% to 63%. The average time to CT head scan was decreased from 69 min to 53 min. Average CT scan reporting time also improved from 98 min to 71 min. Overall, the average time to decision for admission or discharge decreased from 6 hours 48 min to 4 hours 24 min. CONCLUSIONS: Following implementation of the new HI pathway, an improvement in the patient safety and quality of care was noted. High-risk HI patients were picked up earlier, assessed quicker and had CT head scans performed sooner. Decision time for admission/discharge was improved. The HI pathway continues to be used and will be reviewed and re-audited between 3 and 6 months to ensure the sustained improvement.


Asunto(s)
Traumatismos Craneocerebrales , Servicio de Urgencia en Hospital , Mejoramiento de la Calidad , Humanos , Servicio de Urgencia en Hospital/organización & administración , Servicio de Urgencia en Hospital/estadística & datos numéricos , Traumatismos Craneocerebrales/terapia , Adulto , Tomografía Computarizada por Rayos X/métodos , Tomografía Computarizada por Rayos X/estadística & datos numéricos , Tomografía Computarizada por Rayos X/normas , Masculino , Femenino
2.
Resuscitation ; 198: 110181, 2024 May.
Artículo en Inglés | MEDLINE | ID: mdl-38492716

RESUMEN

BACKGROUND: Few data characterize the role of brain computed tomography (CT) after resuscitation from in-hospital cardiac arrest (IHCA). We hypothesized that identifying a neurological etiology of arrest or cerebral edema on brain CT are less common after IHCA than after resuscitation from out-of-hospital cardiac arrest (OHCA). METHODS: We included all patients comatose after resuscitation from IHCA or OHCA in this retrospective cohort analysis. We abstracted patient and arrest clinical characteristics, as well as pH and lactate, to estimate systemic illness severity. Brain CT characteristics included quantitative measurement of the grey-to-white ratio (GWR) at the level of the basal ganglia and qualitative assessment of sulcal and cisternal effacement. We compared GWR distribution by stratum (no edema ≥1.30, mild-to-moderate <1.30 and >1.20, severe ≤1.20) and newly identified neurological arrest etiology between IHCA and OHCA groups. RESULTS: We included 2,306 subjects, of whom 420 (18.2%) suffered IHCA. Fewer IHCA subjects underwent post-arrest brain CT versus OHCA subjects (149 (35.5%) vs 1,555 (82.4%), p < 0.001). Cerebral edema for IHCA versus OHCA was more often absent (60.1% vs. 47.5%) or mild-to-moderate (34.3% vs. 27.9%) and less often severe (5.6% vs. 24.6%). A neurological etiology of arrest was identified on brain CT in 0.5% of IHCA versus 3.2% of OHCA. CONCLUSIONS: Although severe edema was less frequent in IHCA relative to OHCA, mild-to-moderate or severe edema occurred in one in three patients after IHCA. Unsuspected neurological etiologies of arrest were rarely discovered by CT scan in IHCA patients.


Asunto(s)
Edema Encefálico , Reanimación Cardiopulmonar , Paro Cardíaco , Paro Cardíaco Extrahospitalario , Tomografía Computarizada por Rayos X , Humanos , Masculino , Femenino , Estudios Retrospectivos , Tomografía Computarizada por Rayos X/métodos , Tomografía Computarizada por Rayos X/estadística & datos numéricos , Persona de Mediana Edad , Reanimación Cardiopulmonar/métodos , Reanimación Cardiopulmonar/efectos adversos , Anciano , Edema Encefálico/etiología , Edema Encefálico/diagnóstico por imagen , Paro Cardíaco Extrahospitalario/terapia , Paro Cardíaco Extrahospitalario/etiología , Paro Cardíaco Extrahospitalario/diagnóstico por imagen , Paro Cardíaco/terapia , Paro Cardíaco/etiología , Encéfalo/diagnóstico por imagen , Coma/etiología
3.
Radiología (Madr., Ed. impr.) ; 65(4): 291-297, Jul-Ago. 2023. ilus, tab
Artículo en Español | IBECS | ID: ibc-222506

RESUMEN

Introducción: La invaginación intestinal es la introducción de un segmento de asas intestinales en otro segmento adyacente. A diferencia de la población pediátrica, cuya etiología es principalmente idiopática, en el adulto se asocia con mayor frecuencia a patologías graves. El uso cada vez mayor de estudios imagenológicos en la evaluación abdominal ha llevado a mayor detección de invaginaciones intestinales sin enfermedad subyacente, en las que no es posible determinar una causa de base. El objetivo de este estudio fue revisar la presentación clínica, estudio y tratamiento en pacientes con diagnóstico imagenológico de invaginación intestinal en ecografía o tomografía computarizada de abdomen. Método: Se realizó un estudio descriptivo retrospectivo a partir de los informes radiológicos de ecografías y tomografías computarizadas de abdomen obtenidas en un periodo de 10 años en una institución hospitalaria. Resultados: Se obtuvieron 40 casos. En el 10% de ellos, la invaginación intestinal fue un hallazgo incidental en un estudio por otra causa. En el 68% de los casos no se identificó una causa subyacente, demostrándose resolución espontánea en el 75% de los casos con estudio posterior. El síntoma más frecuente fue el dolor abdominal, presente en el 60% de los pacientes. La ubicación más habitual fue entero-enteral en el 90% de los casos. Solo en el 8% de los casos la invaginación intestinal se atribuyó a una causa maligna. Hubo resolución quirúrgica en 7 pacientes. Conclusión: El aumento en el uso de imágenes para el estudio abdominal ha demostrado que existe un porcentaje importante de invaginaciones intestinales que son idiopáticas y que presentarán resolución espontánea.(AU)


Introduction: Intussusception is the insertion of a bowel loop segment into an adjacent segment. Unlike in children, where the condition is mainly idiopathic, intussusception in adults is more often associated with severe disease. The growing use of imaging studies to evaluate the abdomen has resulted in a higher rate of detection of cases of intussusception without underlying disease in which it is not possible to determine the cause. This study aimed to review the clinical presentation, evaluation, and treatment of patients in whom abdominal ultrasonography or computed tomography diagnosed intussusception. Method: We retrospectively reviewed radiology reports of abdominal ultrasound and computed tomography studies done at our hospital in a 10-year period. Results: In the 40 cases found, intussusception was an incidental finding in 10%. No underlying cause was identified in 68%, and posterior imaging studies showed spontaneous resolution in 75%. The most common symptom was abdominal pain, being present in 60%. Intussusception affected only the small bowel in 90% of cases (entero-enteric intussusception). Intussusception was attributed to malignancy in only 8% of cases. In 7 patients, intussusception was resolved surgically. Conclusion: The increased use of abdominal imaging has shown that a significant proportion of cases of intussusception are idiopathic and resolve spontaneously.(AU)


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Intususcepción/diagnóstico por imagen , Intususcepción/etiología , Intestino Delgado/diagnóstico por imagen , Hallazgos Incidentales , Dolor Abdominal , Radiología , Estudios Retrospectivos , Epidemiología Descriptiva , Ultrasonografía/estadística & datos numéricos , Tomografía Computarizada por Rayos X/estadística & datos numéricos
4.
J Pediatr Surg ; 58(1): 111-117, 2023 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-36272813

RESUMEN

BACKGROUND/PURPOSE: "Pan-scanning" pediatric blunt trauma patients leads to exposure to harmful radiation and increased healthcare costs without improving outcomes. We aimed to reduce computed tomography (CT) scans that are not indicated (NI) by imaging guidelines for injured children. METHODS: In July 2017, our Pediatric Trauma Center prospectively implemented validated imaging guidelines to direct CT imaging for trauma activations and consultations for children younger than 16 years old with blunt traumatic injuries. Patients with suspected physical abuse, CT imaging prior to arrival, penetrating mechanism, and instability precluding CT imaging were excluded. We compared CT scanning rates for pre-implementation (01/2016-06/2017) and post-implementation (07/2017-08/2021) time periods. Guideline compliance was evaluated by chart review and sustained through iterative process improvement cycles. RESULTS: During the pre-implementation era, 61 patients underwent 171 CT scans of which 87 (51%) scans were not indicated by guidelines. Post-implementation, 363 patients had 531 scans and only 134 (25%) CTs were not indicated. Total CTs performed declined after initiation of guidelines (2.80 vs 1.46 scans/patient, p<0.0001). Total NI CTs declined (1.41 vs 0.37 NI scans/patient, p<0.0001) reflected in significant reductions in all anatomic regions: head, cervical spine, chest, and abdomen/pelvis. Charges related to NI scans decreased from $1,490.31/patient to $408.21/patient, saving $218,000 in charges. Based on prior utilization, 146 children were spared excessive radiation with no clinically significant missed injuries since guideline implementation. CONCLUSIONS: Quality improvement and implementation science methodologies to enhance compliance with imaging guidelines for children with blunt injuries can significantly reduce unnecessary CT scanning without compromising care. This practice reduces harmful radiation exposure in a sensitive patient population and may save healthcare systems money and resources.


Asunto(s)
Tomografía Computarizada por Rayos X , Procedimientos Innecesarios , Heridas no Penetrantes , Niño , Humanos , Exposición a la Radiación/prevención & control , Tomografía Computarizada por Rayos X/estadística & datos numéricos , Centros Traumatológicos , Heridas no Penetrantes/diagnóstico por imagen , Heridas no Penetrantes/terapia , Guías de Práctica Clínica como Asunto
5.
J Pediatr Surg ; 58(2): 315-319, 2023 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-36418201

RESUMEN

BACKGROUND: Pediatric trauma patients undergo fewer computed tomography (CT) scans when evaluated at pediatric trauma centers (PTC) versus adult trauma centers (ATC) with no change in clinical outcome. Factors contributing to this difference are unclear. We sought to identify whether the training background of physicians, specifically emergency medicine (EM) versus pediatric emergency medicine (PEM), affected the CT rate of pediatric trauma patients within one institution. METHODS: A single-center retrospective study of CT utilization based on attending physicians' training in trauma patients <18 years between November 2018 and November 2020. Attendings were categorized into two groups: EM residency with no PEM fellowship, or pediatrics/EM residency with PEM fellowship. Primary outcomes measured were the proportion of patients receiving a CT and CT positivity rate. RESULTS: Of 463 study patients, CTs were obtained in 145/228 (64%) patients by EM, and 130/235 (55%) by PEM (p=.07). CT positivity rate was 21% and 19% in EM and PEM, respectively (p=.46). The mean number of CTs per patient in EM was 2.8 compared to 2.1 in PEM (p<.01), and for patients with an injury severity score (ISS) >15, mean number of CTs per patient increased to 4.9 in EM versus 2.4 in PEM (p=.01). CONCLUSIONS: The mean number of CTs ordered per patient was statistically higher for EM attendings. The differences between CT rates highlight future opportunities for ongoing development of pediatric trauma imaging guidelines and radiation exposure reduction. LEVELS OF EVIDENCE: Retrospective Study, Level III.


Asunto(s)
Médicos , Tomografía Computarizada por Rayos X , Heridas y Lesiones , Niño , Humanos , Medicina de Emergencia/educación , Medicina de Urgencia Pediátrica/educación , Médicos/estadística & datos numéricos , Estudios Retrospectivos , Tomografía Computarizada por Rayos X/estadística & datos numéricos , Heridas y Lesiones/diagnóstico por imagen
6.
J. health med. sci. (Print) ; 8(3): 141-148, jul.2022. tab, graf
Artículo en Español | LILACS | ID: biblio-1442512

RESUMEN

INTRODUCCIÓN La telerradiología se basa en el despliegue de radiólogos a distancia para evaluar estudios de dicha especialidad. Actualmente hay evidencia limitada sobre las tasas de error de evaluaciones en telerradiología. Este estudio corresponde a una revisión de las discrepancias entre los informes preliminares y finales de tomografía computada (TC) de una unidad de urgencia telerradiológica. OBJETIVO Determinar las discrepancias de las reevaluaciones (addendum) en los informes radiológicos de TC en una unidad de telerradiología de urgencia. MATERIALES Y MÉTODOS La recolección de datos se planificó a modo de tabla de cotejo, en la cual se tabularon casos de reevaluaciones de urgencia desde el mes de enero hasta mayo del año 2021, en base a la categorización Agrawal. RESULTADOS De una total de 111.599, 836 informes presentaron addendum, que corresponden al 0,74% del total informado, La categoría Agrawal 0 agrupó la mayor cantidad de casos y los exámenes de TC especialidad de cuerpo se encuentran los segmentos con mayores requerimientos de reevaluación. Discusión: Los valores obtenidos permiten establecer una baja incidencia de reevaluaciones y de la gravedad de estas, apuntando a errores asociados a canales de comunicación, redacción y elaboración de informes con especial énfasis en estudios TC Tórax y Abdomen/Pelvis. CONCLUSIÓN El porcentaje de cumplimiento de un 99,26% de exactitud en los informes permite concluir la alta confiabilidad y la calidad del servicio de telerradiología de la empresa en cuestión durante el periodo evaluado y el empleo de medidas correctivas basadas en organización, gestión e instrumentalización tecnológica


Asunto(s)
Humanos , Tomografía Computarizada por Rayos X/estadística & datos numéricos , Telemedicina/estadística & datos numéricos , Servicios Médicos de Urgencia/estadística & datos numéricos , Epidemiología Descriptiva
7.
Perm J ; 26(1): 58-63, 2022 04 05.
Artículo en Inglés | MEDLINE | ID: mdl-35609153

RESUMEN

Computed tomography pulmonary angiography (CTPA) is an imaging study for which there is substantial evidence for its overuse in the evaluation of acute pulmonary embolism (PE). Prior literature has reported low positive PE rates, but the variability in positive rates among the ordering physicians has not been as well studied. The purpose of this study was to evaluate variation in ordering and positive rates among physicians in an emergency department (ED) within an integrated health care system.This study was based in a single ED that is part of a geographically isolated integrated health care system. We reviewed the patient records for all patients who underwent a CTPA for the evaluation for acute PE in the ED between January 1, 2018, and December 31, 2019. For each CTPA examination, we recorded the ordering ED physician, serum d-dimer value (mcg/mL), if any, and the results of the CTPA.Review of CTPAs over the 2-year period revealed 1380 CTPAs ordered by 23 ED physicians with a range of 25-141 studies per physician (mean of 60 + 31 CTPAs). The overall positive rate for PE was 6.9%. Individual ED physician positivity rates showed wide variability ranging from 0% to 18.4% (mean positive rate 7.6 + 4.4%). The results of this study confirm the need for greater adherence to existing guidelines using clinical decision rules and d-dimer testing when appropriate among all ED physicians but especially those who order a greater number of studies and have low rates for positive PE.


Asunto(s)
Angiografía , Servicio de Urgencia en Hospital , Embolia Pulmonar , Tomografía Computarizada por Rayos X , Enfermedad Aguda , Angiografía/estadística & datos numéricos , Servicio de Urgencia en Hospital/estadística & datos numéricos , Humanos , Médicos , Embolia Pulmonar/diagnóstico por imagen , Estudios Retrospectivos , Tomografía Computarizada por Rayos X/estadística & datos numéricos
8.
Comput Math Methods Med ; 2022: 8916076, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35281950

RESUMEN

This work was to explore the efficacy of intelligent algorithm-based computed tomography (CT) to evaluate platelet-rich plasma (PRP) combined with vacuum sealing drainage (VSD) in the treatment of patients with pressure ulcers. Based on the u-net network structure, an image denoising algorithm based on double residual convolution neural network (Dr-CNN) was proposed to denoise the CT images. A total of 84 patients who were hospitalized in hospital were randomly divided into group A (without any intervention), group B (PRP treatment), group C (VSD treatment), and group D (PRP+VSD treatment). Procalcitonin (PCT) was detected by enzyme-linked immunosorbent assay (ELISA) combined with immunofluorescence method, C-reactive protein (CRP) was detected by rate reflectance turbidimetry (RRT), and interleukin-6 (IL-6) was detected by electrochemiluminescence method. The results showed that after treatment, 44 cases (52.38%) of pressure ulcers patients recovered, 24 cases (28.57%) had no change in stage, and 16 cases (19.04%) developed pressure ulcers. The pain scores of group D at 1 week (3.35 ± 0.56 points) and 2 weeks (2.76 ± 0.55 points) after treatment were significantly lower than those in group C (7.77 ± 0.58 points and 6.34 ± 0.44 points, respectively). The time of complete wound healing in group D (24.5 ± 2.32) was obviously lower in contrast to that in groups A, B, and C (35.54 ± 3.22 days, 30.23 ± 2 days, and 29.34 ± 2.15 days, respectively). In addition, the medical satisfaction of group D (8.74 ± 0.69) was significantly higher than that of groups A, B, and C (4.69 ± 0.85, 5.22 ± 0.31, and 5.18 ± 0.59, respectively). The levels of IL-6 and PCT in group D were lower than those in groups A, B, and C, and the differences were statistically significant (P < 0.01). The average values of peak signal to noise ratio (PSNR) and structural similarity index measure (SSIM) of the Dr-CNN network model were 37.21 ± 1.09 dB and 0.925 ± 0.01, respectively, which were higher than other algorithms. The mean values of root mean square error (MSE) and normalized mean absolute distance (NMAD) of the Dr-CNN network model were 0.022 ± 0.002 and 0.126 ± 0.012, respectively, which were significantly lower than other algorithms (P < 0.05). The experimental results showed that PrP combined with VSD could significantly reduce the inflammatory response of patients with pressure ulcers. PRP combined with VSD could significantly reduce the pain of dressing change for patients. Moreover, the performance model of image denoising algorithm based on double residual convolutional neural network was better than other algorithms.


Asunto(s)
Algoritmos , Terapia de Presión Negativa para Heridas/métodos , Plasma Rico en Plaquetas/fisiología , Úlcera por Presión/terapia , Adulto , Anciano , Terapia Combinada , Biología Computacional , Aprendizaje Profundo , Femenino , Humanos , Mediadores de Inflamación/sangre , Masculino , Persona de Mediana Edad , Redes Neurales de la Computación , Úlcera por Presión/sangre , Úlcera por Presión/diagnóstico por imagen , Relación Señal-Ruido , Tomografía Computarizada por Rayos X/estadística & datos numéricos , Adulto Joven
9.
Comput Math Methods Med ; 2022: 7638507, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35295203

RESUMEN

Skin computed tomography (CT) image based on improved marching cubes (MC) algorithm was explored to evaluate the therapeutic effect of internal administration of Liangxue Xiaoyin decoction combined with medicated bath in the treatment of psoriasis vulgaris. 712 patients with psoriasis vulgaris blood heat syndrome in hospital were recruited as the research object, which were randomly divided into observation group (TCM oral therapy combined with medicinal bath) and control group (TCM oral therapy), each with 356 cases. Psoriasis area and severity index (PASI), pruritus degree, and clinical treatment effect were compared. The results showed that the reconstruction time of median method was greatly shorter, and the algorithm efficiency was improved by 40.6290%. After treatment, the psoriasis area and severity index (PASI) score of the observation group was 5.61 ± 1.15, ΔPASI = (22.64 ± 2.15). ΔPASI% = 80.14%, which were greatly higher than the control group ((9.41 + 1.56) points, ΔPASI = (18.84 + 1.65) points, ΔPASI% = 66.69%) (P < 0.05). After treatment, the itching degree of the observation group was 3.03 ± 1.01 points, which was lower than that of the control group ((3.71 ± 1.06) points), and the itching degree of the observation group was greater than that of the control group, with substantial difference (P < 0.05). The total effective rate of observation group (88.76%) was higher than that of control group (71.07%) (P < 0.05). Therefore, skin CT image based on the improved MC algorithm can evaluate the therapeutic effect of internal administration of Liangxue Xiaoyin decoction combined with medicated bath in the treatment of psoriasis vulgaris. The internal administration of Liangxue Xiaoyin decoction combined with medicated bath had a good effect on the treatment of psoriasis vulgaris and was of certain clinical application value.


Asunto(s)
Medicamentos Herbarios Chinos/uso terapéutico , Fitoterapia , Psoriasis/diagnóstico por imagen , Psoriasis/tratamiento farmacológico , Adolescente , Adulto , Anciano , Algoritmos , Baños , Biología Computacional , Femenino , Humanos , Masculino , Persona de Mediana Edad , Interpretación de Imagen Radiográfica Asistida por Computador/estadística & datos numéricos , Índice de Severidad de la Enfermedad , Usos Terapéuticos , Tomografía Computarizada por Rayos X/estadística & datos numéricos , Adulto Joven
10.
Comput Math Methods Med ; 2022: 5334095, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35237341

RESUMEN

INTRODUCTION: Considering the narrow window of surgery, early diagnosis of liver cancer is still a fundamental issue to explore. Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICCA) are considered as two different types of liver cancer because of their distinct pathogenesis, pathological features, prognosis, and responses to adjuvant therapies. Qualitative analysis of image is not enough to make a discrimination of liver cancer, especially early-stage HCC or ICCA. METHODS: This retrospective study developed a radiomic-based model in a training cohort of 122 patients. Radiomic features were extracted from computed tomography (CT) scans. Feature selection was operated with the least absolute shrinkage and operator (LASSO) logistic method. The support vector machine (SVM) was selected to build a model. An internal validation was conducted in 89 patients. RESULTS: In the training set, the AUC of the evaluation of the radiomics was 0.855 higher than for radiologists at 0.689. In the valuation cohorts, the AUC of the evaluation was 0.847 and the validation was 0.659, which indicated that the established model has a significantly better performance in distinguishing the HCC from ICCA. CONCLUSION: We developed a radiomic diagnosis model based on CT image that can quickly distinguish HCC from ICCA, which may facilitate the differential diagnosis of HCC and ICCA in the future.


Asunto(s)
Neoplasias de los Conductos Biliares/clasificación , Neoplasias de los Conductos Biliares/diagnóstico por imagen , Carcinoma Hepatocelular/clasificación , Carcinoma Hepatocelular/diagnóstico por imagen , Colangiocarcinoma/clasificación , Colangiocarcinoma/diagnóstico por imagen , Neoplasias Hepáticas/clasificación , Neoplasias Hepáticas/diagnóstico por imagen , Tomografía Computarizada por Rayos X/estadística & datos numéricos , Estudios de Cohortes , Biología Computacional , Diagnóstico Diferencial , Detección Precoz del Cáncer , Femenino , Humanos , Modelos Logísticos , Masculino , Persona de Mediana Edad , Máquina de Vectores de Soporte
11.
BMC Pulm Med ; 22(1): 48, 2022 Jan 31.
Artículo en Inglés | MEDLINE | ID: mdl-35101007

RESUMEN

BACKGROUND: A systematic examination of low-dose CT (LDCT) scan, beside lung nodules, may disclose the presence of undiagnosed diseases, improving the efficacy and the cost/efficacy of these programs. The study was aimed at evaluating the association between LDCT scan findings and non-oncologic and oncologic diseases. METHODS: The LDCT scan of participants to the "Un Respiro per la vita"® lung cancer screening program were checked and abnormal findings, beside lung nodules, recorded. First admission to the acute care because of cardiovascular (CD), respiratory (RD) and oncological diseases (OD) in the following three years were retrieved. The association of LDCT scan abnormal findings with CD, RD and OD was assessed through univariable and multivariable logistic regression models. RESULTS: Mean age of 746 participants was 62 years (SD:5), 62% were male. 11 (1.5%) received a diagnosis of lung cancer. 16.1% participants were admitted to the acute care in the following three years: 8.6% for CD, 4.3% for RD and 5.2% for OD. Valve calcification (OR 2.02, p:0.02) and mucus plugs (OR 3.37, p:0.04) were positively associated with CD, while sub-pleural fibrosis had a protective role (OR 0.47, p:0.01). Lung nodules > 8 mm (OR 5.54, p: < 0.01), tracheal deviation (OR 6.04, p:0.01) and mucus plugs (OR 4.00, p:0.04) were positively associated with OD admissions. Centrilobular emphysema OR for RD admissions was 1.97 (p:0.06). CONCLUSIONS: The observed association between selected LDCT findings and ensuing CD, RD and OD suggests that the information potential of LCDT goes beyond the screening of lung cancer.


Asunto(s)
Detección Precoz del Cáncer/métodos , Detección Precoz del Cáncer/estadística & datos numéricos , Neoplasias Pulmonares/diagnóstico por imagen , Neoplasias Pulmonares/epidemiología , Tomografía Computarizada por Rayos X/estadística & datos numéricos , Anciano , Enfermedad Crónica/epidemiología , Femenino , Humanos , Neoplasias Pulmonares/etiología , Neoplasias Pulmonares/patología , Masculino , Persona de Mediana Edad , Factores de Riesgo , Ciudad de Roma/epidemiología , Fumar/efectos adversos
12.
Comput Math Methods Med ; 2022: 8501828, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35186116

RESUMEN

Computed tomography (CT) is a common modality for liver diagnosis, treatment, and follow-up process. Providing accurate liver segmentation using CT images is a crucial step towards those tasks. In this paper, we propose a stacked 2-U-Nets model with three different types of skip connections. The proposed connections work to recover the loss of high-level features on the convolutional path of the first U-Net due to the pooling and the loss of low-level features during the upsampling path of the first U-Net. The skip connections concatenate all the features that are generated at the same level from the previous paths to the inputs of the convolutional layers in both paths of the second U-Net in a densely connected manner. We implement two versions of the model with different number of filters at each level of each U-Net by maximising the Dice similarity between the predicted liver region and that of the ground truth. The proposed models were trained with 3Dircadb public dataset that were released for Sliver and 3D liver and tumour segmentation challenges during MICCAI 2007-2008 challenge. The experimental results show that the proposed model outperformed the original U-Net and 2-U-Nets variants, and is comparable to the state-of-the-art mU-Net, DC U-Net, and Cascaded UNET.


Asunto(s)
Hígado/diagnóstico por imagen , Redes Neurales de la Computación , Tomografía Computarizada por Rayos X/estadística & datos numéricos , Biología Computacional , Humanos , Imagenología Tridimensional/estadística & datos numéricos , Neoplasias Hepáticas/diagnóstico por imagen , Aprendizaje Automático , Interpretación de Imagen Radiográfica Asistida por Computador/estadística & datos numéricos
13.
BMC Cancer ; 22(1): 179, 2022 Feb 17.
Artículo en Inglés | MEDLINE | ID: mdl-35177018

RESUMEN

BACKGROUND: Sarcopenia predicts poor prognosis of a variety of gastrointestinal malignancies. However, there is a lack of study on the association between skeletal muscle index (SMI) and the prognosis of gastrointestinal stromal tumor (GIST). The aim of this study is to develop a novel nomogram based on sarcopenia for GIST patients to predict overall survival (OS). METHODS: SMI was measured by computed tomography scan of 107 patients who underwent resection for primary localized gastrointestinal stromal tumor (GIST). Sarcopenia was defined by cutoff values for SMI as 40.1 cm2/m2 and 39.8 cm2/m2 using optimum stratification for males and females respectively. Factors were included in the nomogram were specified by univariate and multiple Cox proportional hazard analysis. Concordance index (C-index) and calibration curves were conducted to measure the discrimination and accuracy of the nomogram. The utility of the nomogram was assessed by the decision curve analysis (DCA). RESULTS: Twenty-eight (26.2%) of 107 patients were sarcopenic. Sarcopenia was correlated significantly with body mass index, albumin, female sex, resection style, mitotic index, rupture status, survival. Sarcopenia was significantly related to decreased overall survival (p = 0.003).The nomogram including sarcopenia status, resection style and mitotic index had an excellent discrimination with C-index 0.794. The calibration curves represented a good accordance between the actual observation and nomogram prediction for overall survival. Decision curve analysis illustrated that the nomogram was helpful in clinic. CONCLUSIONS: We developed a nomogram based on sarcopenia to predict overall survival after resection of GISTs which is an effective and favorable prognostication tool.


Asunto(s)
Neoplasias Gastrointestinales/mortalidad , Tumores del Estroma Gastrointestinal/mortalidad , Nomogramas , Sarcopenia/mortalidad , Tomografía Computarizada por Rayos X/estadística & datos numéricos , Femenino , Neoplasias Gastrointestinales/complicaciones , Tumores del Estroma Gastrointestinal/complicaciones , Humanos , Masculino , Persona de Mediana Edad , Músculo Esquelético/diagnóstico por imagen , Músculo Esquelético/patología , Periodo Posoperatorio , Pronóstico , Estudios Retrospectivos , Sarcopenia/diagnóstico por imagen , Sarcopenia/etiología
14.
Comput Math Methods Med ; 2022: 7156598, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35222690

RESUMEN

OBJECTIVE: To explore the 3D-slicer software-assisted endoscopic treatment for patients with hypertensive cerebral hemorrhage. METHODS: A total of 120 patients with hypertensive cerebral hemorrhage were selected and randomly divided into control group and 3D-slicer group with 60 cases each. Patients in the control group underwent traditional imaging positioning craniotomy, and patients in the 3D-slicer group underwent 3D-slicer followed by precision puncture treatment. In this paper, we evaluate the hematoma clearance rate, nerve function, ability of daily living, complication rate, and prognosis. RESULTS: The 3D-slicer group is better than the control group in various indicators. Compared with the control group, the 3D-slicer group has lower complications, slightly higher hematoma clearance rate, and better recovery of nerve function and daily living ability before and after surgery. The incidence of poor prognosis is low. CONCLUSION: The 3D-slicer software-assisted endoscopic treatment for patients with hypertensive intracerebral hemorrhage has a better hematoma clearance effect, which is beneficial to the patient's early recovery and reduces the damage to the brain nerve of the patient.


Asunto(s)
Hemorragia Intracraneal Hipertensiva/diagnóstico por imagen , Hemorragia Intracraneal Hipertensiva/cirugía , Neuroendoscopía/métodos , Cirugía Asistida por Computador/métodos , Tomografía Computarizada por Rayos X/métodos , Adulto , Anciano , Anciano de 80 o más Años , Biología Computacional , Femenino , Hematoma/diagnóstico por imagen , Hematoma/cirugía , Humanos , Imagenología Tridimensional/métodos , Imagenología Tridimensional/estadística & datos numéricos , Hemorragia Intracraneal Hipertensiva/fisiopatología , Masculino , Persona de Mediana Edad , Neuroendoscopía/estadística & datos numéricos , Paracentesis/métodos , Paracentesis/estadística & datos numéricos , Programas Informáticos , Cirugía Asistida por Computador/estadística & datos numéricos , Tomografía Computarizada por Rayos X/estadística & datos numéricos
15.
Comput Math Methods Med ; 2022: 4670003, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35126625

RESUMEN

This research was aimed at exploring the effect of CT images reconstructed by optimized compressed sensing algorithm on postoperative diagnosis of patients with hypertensive heart disease and the influence of Baduanjin on cardiac autonomic nerve function. Based on the compressed sensing algorithm, the maximum likelihood expectation maximization algorithm was introduced to optimize it, and the optimization algorithm was established. The optimized algorithm and filtered back projection algorithm (FBP) were compared regarding the root mean squared error (RMSE), peak signal-to-noise ratio (PSNR), and structural similar image metric (SSIM). A total of 126 patients with hypertensive heart disease who underwent CT examination in the hospital were selected as study subjects. According to whether Baduanjin intervention was adopted, patients were divided into observation group (conventional treatment +Baduanjin) and control group (conventional treatment), with 63 patients in each group. The effect of CT examination on postoperative diagnosis was analyzed. Systolic blood pressure (SBP), diastolic blood pressure (DBP), differential pressure (DP), respiratory rate and heart rate (HR), very low-frequency (VLF) power, low-frequency (LF) power, high-frequency (HF) power, total power (TP) of HR variability, and changes in LF/HF of patients before and after treatment were compared. The RMSE of the compressed sensing optimization algorithm (3.28 ± 0.36) was significantly lower than that of the FBP algorithm (9.25 ± 1.03) (P < 0.05). The SSIM and PNSR of the compressed sensing optimization algorithm were (0.87 ± 0.10) and (21.22 ± 1.60) dB, respectively. The SSIM was significantly higher than the FBP algorithm (P < 0.01), and the PNSR was also higher than the FBP algorithm (P < 0.05). The detection rate of CT for pleural effusion was 16 cases (25.40%) higher than 5 cases (7.94%) with TTE (P < 0.01). After treatment, SBP, DBP, HR, LF, VLF, LF/HF, and DP values in the observation group were lower than those in the control group (P < 0.05), and TP and HF were higher than those in the control group (P < 0.05). It suggested that a novel algorithm was established based on compressed sensing algorithm to improve image quality. CT image had important guiding significance for postoperative diagnosis of heart. Baduanjin intervention could improve the integrated function of patient's autonomic nervous system and the regulation ability of the vagus nerve.


Asunto(s)
Algoritmos , Hipertensión/diagnóstico por imagen , Hipertensión/cirugía , Tomografía Computarizada por Rayos X/estadística & datos numéricos , Adolescente , Adulto , Anciano , Sistema Nervioso Autónomo/fisiopatología , Procedimientos Quirúrgicos Cardíacos , Biología Computacional , Compresión de Datos/estadística & datos numéricos , Terapia por Ejercicio , Femenino , Corazón/diagnóstico por imagen , Corazón/fisiopatología , Humanos , Hipertensión/fisiopatología , Funciones de Verosimilitud , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/diagnóstico por imagen , Periodo Posoperatorio , Relación Señal-Ruido , Telemedicina/estadística & datos numéricos , Resultado del Tratamiento , Adulto Joven
16.
Comput Math Methods Med ; 2022: 5823720, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35126629

RESUMEN

The objective of this study was to explore the accuracy of low-dosage computed tomography (CT) images based on the expectation maximization algorithm denoising algorithm (EM algorithm) in the detection and diagnosis of renal dysplasia, so as to provide reasonable research basis for accuracy improvement of clinical diagnosis of renal dysplasia. 120 patients with renal dysplasia in hospital were randomly selected as the research objects, and they were divided into two groups by random number method, with 60 patients in each group. The low-dosage CT images of patients in the control group were not processed (nonalgorithm group), and the low-dosage CT images of patients in the observation group were denoised using the EM algorithm (algorithm group). In addition, it was compared with the results of the comprehensive diagnosis (gold standard) to analyze the accuracy of the diagnosis of the two groups of patients and the consistency with the results of the pathological diagnosis. The results were compared with those of the comprehensive diagnosis (gold standard) to analyze the accuracy of the diagnosis of the two groups of patients. The results showed that the peak signal-to-noise ratio (PSNR) (15.9 dB) of the EM algorithm was higher than the regularized adaptive matching pursuit (RAMP) algorithm (1.69 dB) and the mean filter (4.3 dB) (P < 0.05). The time consumption of EM algorithm (21 s) was shorter than that of PWLS algorithm (34 s) and MS-PWLS algorithm (39 s) (P < 0.05). The diagnosis accuracy of dysplasia of single kidney, absence of single kidney, horseshoe kidney, and duplex kidney was obviously higher in the algorithm group than the control group (P < 0.05), which were 66.67% vs. 90%, 60% vs. 88.89%, 71.42% vs. 100%, and 60% vs. 88.89%, respectively. The incidence of hypertension in patients with autosomal dominant polycystic kidney disease (ADPKD) (56.77%) was much higher than that of the other diseases (P < 0.05). After denoising by the EM algorithm, low-dosage CT image could improve the diagnostic accuracy of several types of renal dysplasia except ADPKD, showing certain clinical application value. In addition, ADPKD was easy to cause hypertension.


Asunto(s)
Algoritmos , Riñón/anomalías , Riñón/diagnóstico por imagen , Tomografía Computarizada por Rayos X/métodos , Adulto , Anciano , Inteligencia Artificial , Biología Computacional , Femenino , Humanos , Hipertensión/etiología , Masculino , Persona de Mediana Edad , Riñón Poliquístico Autosómico Dominante/complicaciones , Riñón Poliquístico Autosómico Dominante/diagnóstico por imagen , Dosis de Radiación , Reproducibilidad de los Resultados , Relación Señal-Ruido , Tomografía Computarizada por Rayos X/estadística & datos numéricos
17.
Comput Math Methods Med ; 2022: 8195243, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35126635

RESUMEN

This research was to explore the application value of three-dimensional computed tomography (CT) based on artificial intelligent algorithm in analyzing the characteristics of skin lesions in children with psoriasis. In this study, 15 children with psoriasis were selected as the observation group, and 15 children with other skin diseases were selected as the control group. The CT images were optimized, and the feature selection was carried out based on artificial intelligent algorithm. Firstly, the results were compared with the results of simple skin three-dimensional CT to determine the effectiveness. Then, the two groups of three-dimensional skin CT image features of skin psoriasis-like hyperplasia, Munro microabscess, dermal papillary vascular dilation, and squamous epithelium based on intelligent algorithms were compared. After comparison, the detection rate of psoriasis-like hyperplasia, Munro microabscess, dermal papillary vascular dilation, and squamous epithelium in the observation group was higher than that in the control group, with significant difference and statistical significance (P < 0.05). In addition, the sensitivity of psoriasis-like hyperplasia, Munro microabscess, dermal papilla vascular dilatation, and squamous epithelium in children with psoriasis was 80.0%, 86.7%, 80.0%, and 93.3%, respectively. The specificity of psoriasis-like hyperplasia, Munro microabscess, dermal papilla vascular dilatation, and squamous epithelium in children with psoriasis was 86.7%, 93.3%, 60.0%, and 73.3%, respectively. The results showed that Munro microabscess and psoriasis-like hyperplasia had high sensitivity and specificity in all diagnostic items, which could be used as important features of skin lesion sites in the diagnosis of psoriasis in children. The research provides a basis for the clinical diagnosis of psoriasis in children, which is worthy of clinical promotion.


Asunto(s)
Algoritmos , Imagenología Tridimensional/métodos , Psoriasis/diagnóstico por imagen , Piel/diagnóstico por imagen , Tomografía Computarizada por Rayos X/métodos , Absceso/diagnóstico por imagen , Inteligencia Artificial , Estudios de Casos y Controles , Niño , Biología Computacional , Simulación por Computador , Dermis/irrigación sanguínea , Dermis/diagnóstico por imagen , Epitelio/diagnóstico por imagen , Femenino , Humanos , Hiperplasia/diagnóstico por imagen , Imagenología Tridimensional/estadística & datos numéricos , Masculino , Microscopía Confocal/métodos , Microscopía Confocal/estadística & datos numéricos , Interpretación de Imagen Radiográfica Asistida por Computador/métodos , Interpretación de Imagen Radiográfica Asistida por Computador/estadística & datos numéricos , Piel/irrigación sanguínea , Tomografía Computarizada por Rayos X/estadística & datos numéricos
18.
Comput Math Methods Med ; 2022: 7839922, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35111236

RESUMEN

The study is aimed at exploring the application of artificial intelligence algorithm-based magnetic resonance imaging (MRI) in the diagnosis of acute cerebral infarction, expected to provide a reference for diagnosis and effect evaluation of acute cerebral infarction. In this study, 80 patients diagnosed with suspected acute cerebral infarction per Diagnostic Criteria for Cerebral Infarction were selected as the research subjects. MRI images were reconstructed by deep dictionary learning to improve their recognition ability. At the same time, the same diagnostic operation was performed by Computed Tomography (CT) images to compare with MRI. The results of the interalgorithm comparison showed the image reconstruction effect of the deep dictionary learning model is significantly better than SAE reconstruction, single-layer dictionary reconstruction model, and KAVD reconstruction. After comparison, the results of MRI based on artificial intelligence algorithm and CT evaluation were statistically significant (P < 0.05). In the lesion image, the diameter of MRI lesions (3.81 ± 0.77 cm) based on artificial intelligence algorithm and the diameter of lesions in CT (3.66 ± 1.65 cm) also had significant statistical significance (P < 0.05). The results showed that MRI based on deep learning was more sensitive than CT imaging for diagnosis and evaluation of patients with acute cerebral infarction, with only 1 case misdiagnosed. The rate of disease detection and lesion image quality had a higher improvement. The results can provide effective support for the clinical application of MRI based on artificial intelligence algorithm in the diagnosis of acute cerebral infarction.


Asunto(s)
Algoritmos , Infarto Cerebral/diagnóstico por imagen , Infarto Cerebral/terapia , Imagen por Resonancia Magnética/estadística & datos numéricos , Enfermedad Aguda , Anciano , Anciano de 80 o más Años , Inteligencia Artificial , Encéfalo/diagnóstico por imagen , Biología Computacional , Simulación por Computador , Aprendizaje Profundo , Femenino , Humanos , Masculino , Persona de Mediana Edad , Tomografía Computarizada por Rayos X/estadística & datos numéricos , Resultado del Tratamiento
19.
Sci Rep ; 12(1): 1028, 2022 01 19.
Artículo en Inglés | MEDLINE | ID: mdl-35046455

RESUMEN

Lower gastrointestinal perforation is rare and challenging to diagnose in patients presenting with an acute abdomen. However, no study has examined the frequency and associated factors of diagnostic errors related to lower gastrointestinal perforation. This large-scale multicenter retrospective study investigated the frequency of diagnostic errors and identified the associated factors. Factors at the level of the patient, symptoms, situation, and physician were included in the analysis. Data were collected from nine institutions, between January 1, 2015 and December 31, 2019. Timely diagnosis was defined as diagnosis at the first visit in computed tomography (CT)-capable facilities or referral to an appropriate medical institution immediately following the first visit to a non-CT-capable facility. Cases not meeting this definition were defined as diagnostic errors that resulted in delayed diagnosis. Of the 439 cases of lower gastrointestinal perforation identified, delayed diagnosis occurred in 138 cases (31.4%). Multivariate logistic regression analysis revealed a significant association between examination by a non-generalist and delayed diagnosis. Other factors showing a tendency with delayed diagnosis included presence of fever, absence of abdominal tenderness, and unavailability of urgent radiology reports. Initial misdiagnoses were mainly gastroenteritis, constipation, and small bowel obstruction. In conclusion, diagnostic errors occurred in about one-third of patients with a lower gastrointestinal perforation.


Asunto(s)
Abdomen Agudo/diagnóstico , Errores Diagnósticos/estadística & datos numéricos , Perforación Intestinal/diagnóstico , Abdomen Agudo/diagnóstico por imagen , Dolor Abdominal , Anciano , Anciano de 80 o más Años , Femenino , Fiebre , Humanos , Perforación Intestinal/diagnóstico por imagen , Japón , Masculino , Persona de Mediana Edad , Potencial Evento Adverso/estadística & datos numéricos , Médicos/clasificación , Derivación y Consulta/estadística & datos numéricos , Estudios Retrospectivos , Tomografía Computarizada por Rayos X/estadística & datos numéricos
20.
Comput Math Methods Med ; 2022: 7729524, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35047057

RESUMEN

At present, the diagnosis and treatment of lung cancer have always been one of the research hotspots in the medical field. Early diagnosis and treatment of this disease are necessary means to improve the survival rate of lung cancer patients and reduce their mortality. The introduction of computer-aided diagnosis technology can easily, quickly, and accurately identify the lung nodule area as an imaging feature of early lung cancer for the clinical diagnosis of lung cancer and is helpful for the quantitative analysis of the characteristics of lung nodules and is useful for distinguishing benign and malignant lung nodules. Growth provides an objective diagnostic reference standard. This paper studies ITK and VTK toolkits and builds a system platform with MFC. By studying the process of doctors diagnosing lung nodules, the whole system is divided into seven modules: suspected lung shadow detection, image display and image annotation, and interaction. The system passes through the entire lung nodule auxiliary diagnosis process and obtains the number of nodules, the number of malignant nodules, and the number of false positives in each set of lung CT images to analyze the performance of the auxiliary diagnosis system. In this paper, a lung region segmentation method is proposed, which makes use of the obvious differences between the lung parenchyma and other human tissues connected with it, as well as the position relationship and shape characteristics of each human tissue in the image. Experiments are carried out to solve the problems of lung boundary, inaccurate segmentation of lung wall, and depression caused by noise and pleural nodule adhesion. Experiments show that there are 2316 CT images in 8 sets of images of different patients, and the number of nodules is 56. A total of 49 nodules were detected by the system, 7 were missed, and the detection rate was 87.5%. A total of 64 false-positive nodules were detected, with an average of 8 per set of images. This shows that the system is effective for CT images of different devices, pixel pitch, and slice pitch and has high sensitivity, which can provide doctors with good advice.


Asunto(s)
Neoplasias Pulmonares/diagnóstico por imagen , Nódulos Pulmonares Múltiples/diagnóstico por imagen , Nódulo Pulmonar Solitario/diagnóstico por imagen , Algoritmos , Biología Computacional , Diagnóstico por Computador/estadística & datos numéricos , Reacciones Falso Positivas , Humanos , Imagenología Tridimensional/estadística & datos numéricos , Pulmón/diagnóstico por imagen , Distribución Normal , Curva ROC , Interpretación de Imagen Radiográfica Asistida por Computador/estadística & datos numéricos , Tomografía Computarizada por Rayos X/estadística & datos numéricos
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