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1.
BMJ Case Rep ; 17(4)2024 Apr 08.
Artículo en Inglés | MEDLINE | ID: mdl-38589241

RESUMEN

The ampulla portion of the fallopian tube is the most common site of ectopic pregnancy (70%), with approximately 2% of pregnancies implanted in the interstitial portion. In general, an interstitial ectopic pregnancy (IEP) is difficult to diagnose and is associated with a high rate of complications-most patients with an IEP present with severe abdominal pain and haemorrhagic shock due to an ectopic rupture. Chronic tubal pregnancy (CTP) is an uncommon condition with an incidence of 20%. The CTP has a longer clinical course and a negative or low level of serum beta-human chorionic gonadotropin due to perished chorionic villi. This study presents a case of a woman who was diagnosed with a chronic IEP (CIEP) which was successfully treated by surgery. This case also acts as a cautionary reminder of considering a CIEP in women of reproductive age presenting with amenorrhea, vaginal bleeding and a negative pregnancy test.


Asunto(s)
Pruebas de Embarazo , Embarazo Ectópico , Embarazo Tubario , Embarazo , Humanos , Femenino , Embarazo Ectópico/diagnóstico , Embarazo Ectópico/cirugía , Gonadotropina Coriónica Humana de Subunidad beta , Trompas Uterinas/cirugía , Dolor Abdominal/complicaciones , Embarazo Tubario/diagnóstico , Embarazo Tubario/cirugía
2.
Eur J Obstet Gynecol Reprod Biol ; 295: 150-152, 2024 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-38359636

RESUMEN

Ectopic pregnancy is a medical condition in which a fertilized egg takes an unexpected detour away from the uterine cavity and the fallopian tube becomes a popular host, with the ampulla being the prime location. However, it can occur in other areas such as cervix, ovaries, or abdomen. The most common risk factors are pelvic inflammatory disease, previous pelvic or abdominal surgery, abnormal anatomy of genital organs, endometriosis, previous ectopic pregnancies, assisted reproductive technologies, endocrine disorders, and even the subtle influence of low-dose progestins from contraceptives. We will present a rare case of unrecognized late-stage tubal ectopic pregnancy. The following case report is of a 25-year-old Caucasian female patient (G2, P0) who presented to the emergency department with a 24-hour abdominal pain syndrome. The patient did not have a gynecological examination for this reason. During the examination, taking into account the clinical and ultrasound findings, a suspicion of pregnancy in a bicornuate uterus was raised, and an MRI of the pelvis was performed. MRI showed ectopic pregnancy in the left fallopian tube with a properly developed fetus that corresponded to a gestation of 19 weeks. An emergency laparotomy was performed and the left fallopian tube with the fetus was removed. The early and late course of recovery went smoothly. The patient was discharged after adequate clinical development.


Asunto(s)
Embarazo Ectópico , Embarazo Tubario , Embarazo , Femenino , Humanos , Adulto , Embarazo Tubario/diagnóstico por imagen , Embarazo Tubario/cirugía , Embarazo Ectópico/etiología , Trompas Uterinas/diagnóstico por imagen , Trompas Uterinas/cirugía , Abdomen , Dolor Abdominal/etiología
3.
Int Wound J ; 21(1): e14543, 2024 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-38272821

RESUMEN

After several institutions recommended salpingectomy as opposed to tubal ligation, we attempted to perform meta-analysis to compare operative properties and rates of postoperative wound infections. There are no temporal or linguistic limitations to our search in PubMed, Cochrane Library and Embase. The search was carried out in September 2023. The database search identified 401 potential studies and five studies were included in the meta-analysis. Our study involved a comparison of salpingectomy with tube ligating in female patients who wanted to be sterilized. Our trial included at least one result of the wound and haemorrhage. The articles that did not qualify for inclusion or did not submit data, and those who did not answer questions were excluded. Abstracts and full-text articles were assessed independently by two authors using blinding. Conflicting decisions were settled by consensus. The Cochrane-recommended ROBINS-I instrument has been applied to evaluate the risk of bias in clinical trials and to establish the quality of inclusion. Two authors separately evaluated the risk of bias for each trial; differences were settled by consensus. There were no statistically significant differences in the rate of postoperative wound infections among those who had received salpingectomy or tubal ligation (OR, 0.46; 95% CI, 0.18-1.20 p = 0.11). In the three trials, the risk of bleeding following the ligation of the fallopian tubes was lower than that of the salpingectomy group (OR, 1.25; 95% CI, 1.21-1.30 p < 0.0001). From this information we have come to the conclusion that it is possible to give preference to tubal ligation for reduction of bleeding in suitable circumstances, and that the findings currently do not provide sufficient evidence for a reduction in the risk of postoperative wound infection.


Asunto(s)
Esterilización Tubaria , Humanos , Femenino , Infección de la Herida Quirúrgica/prevención & control , Salpingectomía , Trompas Uterinas/cirugía
4.
J Minim Invasive Gynecol ; 31(3): 178-179, 2024 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-38030033

RESUMEN

OBJECTIVE: To demonstrate and discuss a case of primary hepatic ectopic pregnancy and laparoscopic management. DESIGN: Case presentation with demonstration of surgical hepatic wedge resection. SETTING: Tertiary referral center in Manchester, United Kingdom. INTERVENTIONS: A 33-year-old women gravida 13 para 2 with a body mass index of 55 kg/m2 and previous 2 cesarean sections and a laparoscopic cholecystectomy presented to the emergency services after a private ultrasound scan showing a pregnancy of unknown location and a serum human chorionic gonadotropin (hCG) of 18 336 IU/mL. A diagnostic laparoscopy was performed but fallopian tubes were normal with no signs of ectopic pregnancy seen. An abdominal ultrasound scan was performed but did not identify the ectopic pregnancy. Owing to worsening symptoms of pain and rising hCG levels, she underwent a further laparoscopy converted to laparotomy and a left salpingo-oophorectomy for suspected left ovarian pregnancy. However, serum hCG levels continued to rise after the surgery, reaching 36 960 IU/mL. An magnetic resonance imaging scan of her abdomen and pelvis was arranged that showed a 4 cm cystic lesion in the segment V of the liver. Further ultrasound correlation showed a hyperechoic lesion with echogenic components suspicious of an ectopic pregnancy with a fetal pole. Fetal heart action was not visualized. A multidisciplinary team approach was adopted with involvement of the hepatobiliary surgical team, and the option of medical management with methotrexate and surgical excision was considered. A decision was made for surgical excision based on the accessible location of the ectopic pregnancy on segment V and the more controlled and predictable outcome with surgical excision. A preoperative computed tomography scan confirmed the lesion in segment V of liver in keeping with liver capsular implantation of ectopic pregnancy (Video still 1). At laparoscopy the ectopic pregnancy was visualized on the inferior surface of liver close to the inferior margin with a band of overlying omental adhesion (Video still 2). The overlying omental adhesions were sealed and cut with advanced bipolar diathermy, keeping a safe margin from the ectopic pregnancy to minimize any bleeding. The liver capsule was then opened with monopolar diathermy, and the small segment of liver with the ectopic pregnancy was excised using a combination of Bowa-Lotus liver blade (Bowa Medical Ltd). Hemostasis was controlled using Floseal hemostatic matrix and applied pressure laparoscopically. Total operating time was 80 minutes with an estimated blood loss of 500 mL. The patient was discharged on day 3 postoperatively, and follow-up serum hCG excluded residual trophoblastic disease. On review of the clinical case, earlier imaging of the upper abdomen when confronted by a persistent pregnancy of unknown location with high levels of serum hCG would have prevented the second laparoscopy, laparotomy, and salpingo-oophorectomy. In similar cases, it would also help exclude poorly differentiated malignancies as a source of serum hCG. CONCLUSION: Only 27 cases of ectopic pregnancy on the liver have been identified in English literature since 1952, based on a MEDLINE and Embase enquiry and further review of all case reports by the authors to avoid duplicates. Estimated incidence of hepatic implantation is 1 in 15 000 pregnancies; 4 case reports of laparoscopic liver resection have been identified and another case managed by suction from the liver surface [1,2]. The key principle demonstrated is to resect the ectopic pregnancy with a safe margin of liver tissue and any adhesions to avoid catastrophic bleeding from direct handling of the ectopic pregnancy.


Asunto(s)
Laparoscopía , Embarazo Ectópico , Embarazo , Femenino , Humanos , Adulto , Embarazo Ectópico/diagnóstico por imagen , Embarazo Ectópico/cirugía , Metotrexato , Laparoscopía/métodos , Trompas Uterinas/cirugía , Hígado
5.
J Minim Invasive Gynecol ; 31(2): 155-160, 2024 02.
Artículo en Inglés | MEDLINE | ID: mdl-37984516

RESUMEN

Epithelial ovarian and fallopian cancers are aggressive lesions that rarely metastasize to the central nervous system. Brain metastases usually occur in the setting of known primary disease or widespread metastatic disease. However, in extremely rare cases, an isolated intracranial neoplasm may be the first presentation of fallopian cancer. To the best of our knowledge, only one such case has been reported previously. We present an illustrative case with multimodality imaging and histopathologic correlation of a fallopian tube carcinoma first presenting with altered mental status secondary to an isolated brain metastasis. A 64-year-old female with no pertinent medical history presented with altered mentation. Initial workup identified a 1.6 cm avidly enhancing, solitary brain lesion at the gray-white junction with associated vasogenic edema concerning for either central nervous system lymphoma or metastatic disease. Additional imaging identified a 7.5 × 3 cm left adnexal lesion, initially thought to be a hydrosalpinx with hemorrhage, but magnetic resonance imaging suggested gynecologic malignancy. No lesions elsewhere in the body were identified. Given the lack of locoregional or systemic disease, the intracranial and pelvic lesions were assumed to represent synchronous but distinct processes. The intracranial lesion was biopsied. Preliminary results were suggestive of lymphoma, but further analysis was consistent with high-grade serous carcinoma of müllerian origin. Positron emission tomography/computed tomography was performed to evaluate for other neoplastic lesions, only highlighting the intracranial and pelvic lesions. At this point, a diagnosis of metastatic fallopian cancer was made. The patient was taken for robot-assisted laparoscopy with surgical debulking of the pelvic neoplasm, pathology demonstrating high-grade serous carcinoma of the fallopian tube, matching that of the intracranial lesion. Even though rare, metastatic fallopian cancer should be considered in patients with isolated brain lesions and adnexal lesions, even in the absence of locoregional or systemic disease.


Asunto(s)
Neoplasias Encefálicas , Carcinoma , Neoplasias de las Trompas Uterinas , Linfoma , Neoplasias Ováricas , Humanos , Femenino , Persona de Mediana Edad , Trompas Uterinas/cirugía , Neoplasias Ováricas/cirugía , Neoplasias Ováricas/patología , Neoplasias de las Trompas Uterinas/cirugía , Neoplasias de las Trompas Uterinas/patología , Neoplasias Encefálicas/cirugía , Neoplasias Encefálicas/patología , Encéfalo , Linfoma/patología
7.
Medicine (Baltimore) ; 102(47): e36165, 2023 Nov 24.
Artículo en Inglés | MEDLINE | ID: mdl-38013278

RESUMEN

BACKGROUND: Ectopic pregnancy is a common gynecological emergency that poses a significant risk of maternal mortality during the first trimester. It also increases the incidence of infertility and repeated ectopic pregnancy. The aim of this study was to evaluate whether there is a difference in the degree of tubal patency between salpingostomy and systemic treatment with methotrexate (MTX), as well as the odds of intrauterine pregnancy and repeat ectopic pregnancy, and the degree of tubal patency in salpingectomy with or without tubal suturing. METHODS: We searched PubMed, EMBASE, and the Cochrane Library up to April 2023. Four randomized controlled trials were included in the review. We analyzed the combined data using Review Manager 5.3 software and Stata 12.0 software, utilizing a random effects model. RESULTS: When comparing salpingostomy and systemic treatment with MTX, there was no significant difference in the degree of tubal patency (OR = 1.09, 95% CI (0.54-2.38), P = .83). For salpingostomy with or without tubal suturing, there were no significant differences in the rates of intrauterine pregnancy, repeat ectopic pregnancy, and tubal patency degree [(OR = 1.05, 95% CI (0.41-2.68), P = .92), (OR = 0.68, 95% CI (0.19-2.42), P = .92), (OR = 1.68, 95% CI (0.14-20.33), P = .68)]. CONCLUSION: This meta-analysis demonstrates that systemic treatment with MTX is an effective treatment for patients who wish to preserve their fallopian tubes without undergoing surgery. This form of treatment can help avoid surgical procedures that may damage the fallopian tubes and improve fertility prospects. If choosing surgery, we believe that opting for salpingostomy without tubal suturing could reduce the operation time and minimize damage.


Asunto(s)
Embarazo Ectópico , Embarazo Tubario , Embarazo , Femenino , Humanos , Embarazo Tubario/cirugía , Embarazo Ectópico/cirugía , Trompas Uterinas/cirugía , Salpingostomía/métodos , Metotrexato , Resultado del Tratamiento
8.
Rev Med Liege ; 78(11): 634-640, 2023 Nov.
Artículo en Francés | MEDLINE | ID: mdl-37955293

RESUMEN

Ectopic pregnancy is a gynecological emergency. The hCG level, the clinical presentation and the ultrasound remain the key steps for the diagnosis. The criteria tend to be more and more codified to decide on the optimal treatment, however, there is no consensus. The aim of this study was to evaluate the impact of applying a mathematical formula to predict the failure rate of metho-trexate for tubal ectopic pregnancy. A retrospective, monocentric study was conducted on a cohort of 193 patients for whom the formula could be calculated. Regarding our professional practice, the success rate of first-line metho-trexate is 93 %. It would increase to 96 % if the formula had been applied. The use of the formula would also reduce the rate of first-line surgery by 12 %.


La grossesse extra-utérine est une urgence gynécologique. Le taux d'hCG, la clinique et l'échographie restent les examens clé pour le diagnostic. Les critères tendent à être de plus en plus codifiés pour décider du traitement optimal. Cependant, il n'existe aucun consensus. Le but de cette étude était d'évaluer l'impact de l'application d'une formule mathématique permettant de prédire le taux d'échec du méthotrexate pour une grossesse extra-utérine tubaire. Une étude rétrospective et monocentrique a été menée sur une cohorte de 193 patientes pour lesquelles la formule a pu être calculée. Concernant notre pratique professionnelle, le taux de réussite du méthotrexate en 1ère intention est de 93 %. Il passerait à 96 % si la formule avait été appliquée. L'emploi de la formule permettrait également de diminuer de 12 % le taux de chirurgie réalisée en première intention.


Asunto(s)
Embarazo Ectópico , Embarazo Tubario , Embarazo , Femenino , Humanos , Metotrexato/uso terapéutico , Estudios Retrospectivos , Trompas Uterinas/cirugía , Embarazo Tubario/tratamiento farmacológico , Embarazo Tubario/cirugía , Embarazo Ectópico/tratamiento farmacológico , Embarazo Ectópico/diagnóstico , Embarazo Ectópico/cirugía
9.
BMJ Case Rep ; 16(11)2023 Nov 23.
Artículo en Inglés | MEDLINE | ID: mdl-37996138

RESUMEN

Primary fallopian tube carcinoma (PFTC) is a rare disease. Its location, close association with epithelial ovarian carcinoma, and lack of specific signs and symptoms make diagnosis challenging especially in its early stages. We report a postmenopausal patient who presented with a 2-month history of abdominopelvic pain with watery vaginal discharge. Imaging findings showed a 7 cm complex left adnexal mass. The patient underwent a robotic-assisted total laparoscopic hysterectomy and bilateral salpingo-oophorectomy and surgical staging. Findings were significant for stage IA serous fallopian tube carcinoma. PFTC is sometimes missed preoperatively and intraoperatively. Available literature review has focused on the clinical and imaging characteristics of PFTC to aid in timely disease diagnosis. Minimally invasive surgery is a viable option in the diagnosis and management of early-stage ovarian cancer due to improved visualisation of pelvic structures, decreased length of hospital stay, decreased estimated blood loss and lower postoperative complication rates compared with laparotomy.


Asunto(s)
Neoplasias de las Trompas Uterinas , Neoplasias Ováricas , Femenino , Humanos , Trompas Uterinas/cirugía , Trompas Uterinas/patología , Neoplasias de las Trompas Uterinas/diagnóstico , Neoplasias de las Trompas Uterinas/cirugía , Neoplasias de las Trompas Uterinas/patología , Carcinoma Epitelial de Ovario , Histerectomía , Neoplasias Ováricas/cirugía
10.
BMJ Case Rep ; 16(10)2023 Oct 10.
Artículo en Inglés | MEDLINE | ID: mdl-37816580

RESUMEN

Ectopic pregnancy accounts for 1-2% of all pregnancies. Ultrasound is the primary diagnostic tool to locate pregnancy outside the uterus and identify complications such as haemoperitoneum. In inconclusive cases, MRI is an adjunctive imaging modality offering more precise tissue differentiation and helpful to location identification. Presented is an unusual case of tubal pregnancy. The patient in her 30s, who was 14 weeks into her first pregnancy, had a suspected abdominal pregnancy. Both transabdominal ultrasound and an MRI indicated an ectopic pregnancy, likely originating from the right fallopian tube. A successful laparotomy and right salpingectomy were performed without complications. Rarely, as in this case, large unruptured and advanced tubal pregnancies can mimic an abdominal pregnancy, underscoring the importance of disease recognition and familiarity with uncommon image findings. An accurate diagnosis of pregnancy location is crucial for effective case management.


Asunto(s)
Embarazo Abdominal , Embarazo Tubario , Femenino , Humanos , Embarazo , Trompas Uterinas/diagnóstico por imagen , Trompas Uterinas/cirugía , Embarazo Abdominal/diagnóstico por imagen , Embarazo Abdominal/cirugía , Embarazo Tubario/diagnóstico por imagen , Embarazo Tubario/cirugía , Salpingectomía , Útero , Adulto
11.
Ugeskr Laeger ; 185(29)2023 07 17.
Artículo en Danés | MEDLINE | ID: mdl-37539800

RESUMEN

In this case report, a woman with no risk factors was admitted with bilateral tubal ectopic pregnancy. Bilateral ectopic pregnancy is a rare clinical condition with clinical findings which in their symptoms do not differ from those of unilateral ectopic pregnancy. The condition can therefore easily be missed. The risk of rupture and haemorrhagic shock might be increased because of the increased danger of both tubes presenting with complications. Thus, it is important to examine both adnexa by transvaginal ultrasound. Even if unilateral ectopic pregnancy is considered before operation, the inspection of the abdomen, especially of the other fallopian tube, must always be done during surgery.


Asunto(s)
Embarazo Ectópico , Embarazo Tubario , Embarazo , Femenino , Humanos , Embarazo Tubario/cirugía , Embarazo Ectópico/cirugía , Trompas Uterinas/diagnóstico por imagen , Trompas Uterinas/cirugía , Ultrasonografía , Rotura
12.
J Med Case Rep ; 17(1): 351, 2023 Aug 18.
Artículo en Inglés | MEDLINE | ID: mdl-37592269

RESUMEN

BACKGROUND: At the time of benign gynecological surgery, a prophylactic salpingo-oophorectomy or salpingectomy is increasingly being performed concurrently to reduce the risk of future ovarian and fallopian tube cancer. We herein describe a case of hereditary breast and ovarian cancer syndrome in which a hysterectomy and bilateral adnexectomy were performed with a preoperative diagnosis of benign tumor. A detailed pathological examination revealed occult fallopian tube cancer, and additional staging surgery provided an accurate pathology diagnosis. CASE PRESENTATION: A 72-year-old Japanese woman with a past history of breast cancer underwent a hysterectomy and bilateral oophoro-salpingectomy for the preoperative diagnosis of uterine myoma and a right para-ovarian cyst. In the detailed pathological examination, high-grade serous carcinoma of the right fallopian tube was detected incidentally, and a subsequent staging laparotomy confirmed single para-aortic lymph node metastasis. Furthermore, a mutation in germline BRCA2 was detected postoperatively, and the patient was finally diagnosed with hereditary breast and ovarian cancer syndrome. She was diagnosed with fallopian tube cancer International Federation of Gynecology and Obstetrics Stage IIIA1(i) and started on adjuvant therapy (six courses of paclitaxel and carboplatin followed by maintenance therapy with olaparib), and 18 months after surgery, she was free of disease. CONCLUSION: This is a case of fallopian tube cancer that was diagnosed incidentally and then accurately staged with additional advanced staging surgery. Even in the absence of grossly malignant findings, a detailed pathological search of the fallopian tubes and accurate staging surgery are important to make the necessary treatment decisions for the patient.


Asunto(s)
Neoplasias de las Trompas Uterinas , Síndrome de Cáncer de Mama y Ovario Hereditario , Neoplasias Ováricas , Femenino , Embarazo , Humanos , Anciano , Neoplasias de las Trompas Uterinas/diagnóstico , Neoplasias de las Trompas Uterinas/cirugía , Neoplasias Ováricas/diagnóstico , Neoplasias Ováricas/genética , Mama , Trompas Uterinas/cirugía
13.
Am J Case Rep ; 24: e940111, 2023 Aug 08.
Artículo en Inglés | MEDLINE | ID: mdl-37550961

RESUMEN

BACKGROUND Tubal heterotopic pregnancy is an extremely rare complication of pregnancy, in which there is a simultaneous presence of a pregnancy in the uterine cavity and in an ectopic location, most commonly in the fallopian tube. The management of such cases is not clearly established. In the case of a desire to maintain an intrauterine pregnancy, the surgical procedure consisting of a salpingectomy or salpingostomy is the most common. Such a procedure is effective, but it involves potential complications typical of surgeries, so, in some cases, it seems reasonable to apply the expectant management. CASE REPORT A 31-year-old woman was admitted to the clinic due to pain in the right lower abdomen. An ultrasound examination revealed a gestational sac in the uterine cavity corresponding to 5 weeks of pregnancy with a yolk sac. A twin sac was found in the right fallopian tube. Due to the patient's mild symptoms, absence of bleeding into the peritoneal cavity, concerns about the safety of the embryo and the pregnant woman in case of surgery, conservative management was decided. On the 20th day, the patient was discharged from the clinic with a viable intrauterine pregnancy and a partially absorbed ectopic pregnancy. CONCLUSIONS In the case of an ectopic tubal pregnancy, if there are no symptoms of bleeding into the peritoneal cavity, it is possible to adopt a safe conservative approach with strict patient observation.


Asunto(s)
Embarazo Heterotópico , Embarazo Tubario , Embarazo , Femenino , Humanos , Adulto , Embarazo Heterotópico/diagnóstico por imagen , Embarazo Heterotópico/cirugía , Tratamiento Conservador , Embarazo Tubario/diagnóstico por imagen , Embarazo Tubario/cirugía , Trompas Uterinas/cirugía , Salpingostomía
14.
Fertil Steril ; 120(3 Pt 2): 553-562, 2023 09.
Artículo en Inglés | MEDLINE | ID: mdl-37495011

RESUMEN

Nontubal ectopic pregnancies occur as a result of embryo implantation outside the uterine cavity and fallopian tubes. Sites include ovary, cervix, abdominal cavity, interstitial portion of fallopian tube, and cesarean scar. Nontubal pregnancies are uncommon. Nonspecific signs and symptoms of nontubal ectopic pregnancies make diagnosis challenging and, in many cases, significantly delayed, resulting in a high rate of morbidity. Although surgical management remains the mainstay of treatment, there is growing evidence that some of these can be managed medically or with the use of a combination of medical and surgical approaches with good outcome. This review summarizes the current diagnostic modalities, therapeutic options, and outcomes for nontubal ectopic pregnancies. Diagnostic and management options may be limited, especially in resource-restricted settings. Therefore, an understanding of the available options is critical. It needs to be emphasized that the rarity of cases and the difficulties in organizing ethically justified randomized trials result in the lack of well-established management guidelines for nontubal ectopic pregnancies.


Asunto(s)
Embarazo Ectópico , Embarazo , Femenino , Humanos , Embarazo Ectópico/diagnóstico , Embarazo Ectópico/epidemiología , Embarazo Ectópico/terapia , Trompas Uterinas/cirugía , Cuello del Útero
15.
J Pak Med Assoc ; 73(6): 1302-1304, 2023 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-37427636

RESUMEN

A 27-year-old married woman came to the emergency room (ER) with the chief complaint of severe pain in the abdomen for 3 days, which was more pronounced in the right iliac fossa, along with the complaint of multiple episodes of vomiting for the last 6 hours. She also gave a history of swelling in the right inguinal region for last 9 months with the complaint of mild on and off pain in the swelling. On physical examination, diagnosis of obstructed inguinal hernia was made. Ultrasonography (USG) of abdomen was of no use, as it only commented on hernial defect and not on the contents of the hernial sac. An emergency surgery was planned; marsupialisation of ovarian cyst, repositioning of fallopian tube along with ovary and herniorrhaphy was performed without any difficulty.


Asunto(s)
Hernia Inguinal , Herniorrafia , Quistes Ováricos , Adulto , Femenino , Humanos , Cavidad Abdominal , Trompas Uterinas/cirugía , Hernia Inguinal/diagnóstico , Hernia Inguinal/diagnóstico por imagen , Hernia Inguinal/cirugía , Quistes Ováricos/diagnóstico , Quistes Ováricos/diagnóstico por imagen , Quistes Ováricos/cirugía , Herniorrafia/métodos
16.
BMC Pediatr ; 23(1): 282, 2023 06 06.
Artículo en Inglés | MEDLINE | ID: mdl-37280586

RESUMEN

BACKGROUND: Upstream infection with vaginal flora can develop into tubal endothelial damage and tubal edema, which can lead to tubal obstruction and fallopian tube abscess if left untreated. Fallopian tube abscess in adolescent virgins is very rare, it may lead to long-term or even lifelong complications once it occurred. CASE PRESENTATION: A 12-year-old adolescent virgin with no history of sexual intercourse and previous physical fitness who presented with lower abdominal pain with nausea and vomiting for 22 h, body temperature up to 39.2 °C. Laparoscopic surgery revealed an abscess in the left fallopian tube, the left fallopian tube was surgically removed, successfully treated, and the pus was cultured for escherichia coli. CONCLUSION: It is important to consider possibility of tubal infection in young.


Asunto(s)
Enfermedades de las Trompas Uterinas , Laparoscopía , Femenino , Adolescente , Humanos , Niño , Trompas Uterinas/cirugía , Absceso , Enfermedades de las Trompas Uterinas/complicaciones , Enfermedades de las Trompas Uterinas/cirugía , Dolor Abdominal/etiología , Laparoscopía/efectos adversos
17.
Hum Reprod ; 38(8): 1445-1448, 2023 08 01.
Artículo en Inglés | MEDLINE | ID: mdl-37295950

RESUMEN

Ectopic pregnancy is a risk of both spontaneous and assisted reproduction pregnancies. The majority of ectopic pregnancies abnormally implant within a fallopian tube (extrauterine pregnancies). In haemodynamically stable women, medical or expectant treatment can be offered. Currently accepted medical treatment is using a drug called methotrexate. However, methotrexate has potential adverse effects, and a significant proportion of women will still require emergency surgery (up to 30%) to remove the ectopic pregnancy. Mifepristone (RU-486) has anti-progesterone effects and has a role in managing intrauterine pregnancy loss and termination of pregnancy. On reviewing the literature and given progesterone's pivotal role in sustaining pregnancy, we propose that we may have overlooked the role of mifepristone in the medical management of tubal ectopic pregnancy in haemodynamically stable women.


Asunto(s)
Embarazo Ectópico , Embarazo Tubario , Embarazo , Femenino , Humanos , Mifepristona/uso terapéutico , Metotrexato/uso terapéutico , Embarazo Tubario/tratamiento farmacológico , Embarazo Tubario/cirugía , Trompas Uterinas/cirugía
18.
Cell Mol Biol (Noisy-le-grand) ; 69(4): 101-104, 2023 Apr 30.
Artículo en Inglés | MEDLINE | ID: mdl-37329541

RESUMEN

This experiment was carried out to investigate the effect of combined treatment of tubal obstruction infertility with deacetylated chitosan and two microscopes on the levels of IFN-γ and ICAM-1. In this study, 100 infertile patients with fallopian tube obstruction who were treated in Jiangbei District Hospital of traditional Chinese medicine from January to August 2019 were divided into two groups according to the alternating grouping method, group A (50 cases) received combined surgery, and Group B (50 cases) received combined surgery and chitosan. The curative effect and postoperative pelvic adhesion of the two groups were analyzed, and the levels of IFN-γ, ICAM-1 and IL6(IL-6), laminin (LN), Transforming growth factor beta 1(TGF-ß1) and fibronectin (FN) were observed before and after treatment. Results showed that the total effective rate of Group B was higher than that of Group A (92. 00% vs 76. 00%). The incidence of pelvic adhesion was lower in Group A (4. 00% vs 16. 00%) (P < 0.05). The levels of IFN-γ, ICAM-1, IL-6, LN, FN and TGF-ß1 in Group B were significantly lower than those in group A (P < 0.05). In conclusion, the treatment of tubal obstruction infertility with combined deacetylated chitosan and biendoscopy is effective, which can reduce the levels of IFN-γ and ICAM-1, improve the expression of adhesion-related factors and reduce the occurrence of pelvic adhesion.


Asunto(s)
Quitosano , Enfermedades de las Trompas Uterinas , Infertilidad , Femenino , Humanos , Trompas Uterinas/cirugía , Factor de Crecimiento Transformador beta1 , Quitosano/uso terapéutico , Laparoscopios , Histeroscopios , Molécula 1 de Adhesión Intercelular , Interleucina-6 , Enfermedades de las Trompas Uterinas/complicaciones , Enfermedades de las Trompas Uterinas/cirugía , Interferón gamma
19.
Eur J Contracept Reprod Health Care ; 28(4): 227-233, 2023 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-37365993

RESUMEN

PURPOSE: Many concerns have been raised about adverse effects related to Essure® device. Several pathophysiological hypotheses have been proposed including allergic reactions, Autoimmune/Autoinflammatory Syndrome Induced by Adjuvants, galvanic corrosion with release of heavy metals and inflammation. In the present study, we aimed to focus on inflammation process by performing a histopathological evaluation of Fallopian tubes in symptomatic patients with Essure® removal. MATERIALS AND METHODS: A cross-sectional study with identification of the type of inflammatory response and characterisation of inflammatory cells in the surrounding tubal tissue around the Essure® (STTE) and at distance from the implant. Histopathological and clinical correlations were also investigated. RESULTS: In the STTE from 47 cases, acute inflammation was observed in 3/47 (6.4%) cases. Chronic inflammation with lymphocytes (42.5%, 20/47) was associated with a significant higher pre-operative pain score (p = .03). Fibrosis was noted in 43/47 (91.5%) cases. Fibrosis without lymphocytes (51.1%, 24/47) was statistically associated with significant reduced pain (p = .04). At distance from the Essure® implant, only chronic inflammation with lymphocytes was present in 10/47 (21.7%) cases. CONCLUSIONS: Inflammation response do not seem to be enough to explain all the Essure-related adverse outcomes, suggesting the involvement of other biological mechanisms. CLINICALTRIALS.GOV IDENTIFIER: NCT03281564.


Inflammation and fibrosis are found in the surrounding tubal tissue around the Essure®. Inflammation process alone doesn't seem to be enough to explain symptomatology.


Asunto(s)
Esterilización Tubaria , Femenino , Humanos , Embarazo , Estudios Transversales , Esterilización Tubaria/efectos adversos , Remoción de Dispositivos , Salpingectomía , Trompas Uterinas/cirugía , Dolor/etiología , Inflamación/etiología , Histeroscopía
20.
JNMA J Nepal Med Assoc ; 61(261): 465-468, 2023 May 01.
Artículo en Inglés | MEDLINE | ID: mdl-37203904

RESUMEN

Benign tumors of the fallopian tube are uncommon. Teratomas are most frequently found in the ovary and fallopian tube teratoma is extremely rare. To date, around 70 cases have been described, and most of them were discovered by chance. Here we present two cases of fallopian tube dermoid cyst. The first case is of a woman who was unable to conceive for 4 years with a right ovarian dermoid. She was managed with laparoscopic cystectomy when she was found to have a small teratoma-like lesion at the fimbrial end of the left fallopian tube. The second case is of a female who underwent elective caesarian section and was found to have a teratoma-like lesion at the right fallopian tube. Histopathology of both cases were reported as mature cystic teratoma. These cases suggest the need for careful examination of the pelvic organs for other pathology apart from the primary surgical sites. Keywords: case reports; dermoid cyst; fallopian tube; infertility.


Asunto(s)
Quiste Dermoide , Neoplasias de las Trompas Uterinas , Neoplasias Ováricas , Teratoma , Embarazo , Femenino , Humanos , Trompas Uterinas/cirugía , Trompas Uterinas/patología , Quiste Dermoide/diagnóstico , Quiste Dermoide/cirugía , Quiste Dermoide/patología , Teratoma/diagnóstico , Teratoma/cirugía , Neoplasias Ováricas/diagnóstico , Neoplasias Ováricas/cirugía , Neoplasias Ováricas/patología , Neoplasias de las Trompas Uterinas/diagnóstico , Neoplasias de las Trompas Uterinas/cirugía , Neoplasias de las Trompas Uterinas/patología
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