Avaliação do efeito imediato e residual do sabão anti-séptico, do PVP-I degermante, do PVP-I tópico e da clorexidina na degermação das mãos / Evaluation of immediate and residual effect of liquid soap, degerming povidine-iodine, topic povodine-iodine and chlorhexidine on handwashing

O objetivo deste trabalho foi avaliar o efeito imediato e residual da água e do sabão bactericida, do PVP-I degermante, do PVP-I tópico e da clorexidina na degermação das mãos de graduandos da Faesa-Vitória, em procedimentos críticos. A coleta microbiológica foi realizada antes da degermação, após a degermação e uma hora após o uso de luvas. Foi possível concluir que: houve diferença significante entre o grupo água e sabão e os demais; a lavagem das mãos com água e sabão não inibiu o crescimento de Staphylococcus sp imediatamente; o PVP-I degermante e o PVP-I tópico e a clorexidina impediram o crescimento de qualquer micro-organismo no ato de seu uso e 1 hora depois

Comparison of two pre-surgical skin preparation techniques.

A one-step iodophor skin preparation solution was compared to chlorhexidine gluconate application as a pre-operative skin preparation method in 100 animals undergoing elective ovariohysterectomy. Pre-operative and intra-operative skin cultures demonstrated no difference in antiseptic efficacy. No animal in the study demonstrated signs of systemic infection, and no adverse local effects from either antiseptic were seen. The iodophor solution evaluated (DuraPrep) is a safe and effective pre-operative skin preparation agent in small animal patients undergoing clean surgical procedures.

Suitability of a propanolic PVP-iodophor preparation as preoperative skin disinfectant: germicidal activity and chemical stability.

The preparation Solutio Betadini propanolica 3% w/w, used as a pre-operative skin disinfectant was examined for its germicidal activity and its chemical stability. The additive activity of iodine and propanol resulted in a wide range of antimicrobial activity against bacteria, including bacterial spores, and fungi, with a rapid onset and sustained duration of action. The solution is easily manufactured and analyzed, its stability is guaranteed for 6 months. Because of its staining property, there is no need of coloured additives to mark the disinfected area. In addition, no skin irritations by the disinfectant were observed so far. Thus, the preparation fulfills the essential requirements for preoperative skin disinfectants and is suitable for the preparation and the compounding in hospital pharmacies.

A microbiological in-use comparison of surgical hand-washing agents.

Seven different surgical hand-scrub agents (one triclosan compound, two hexachlorophene compounds, and four iodophors) were evaluated under in-use conditions by five persons for efficacy in degerming the hands and forearms prior to performing a total of 215 total hip arthroplasties. With all of the compounds tested there was a significant reduction (p less than or equal to 0.001) of indigenous skin microflora from prescrub levels at both the post-scrub and postoperative points. The two hexachlorophene compounds in general revealed a bacteriostatic effect whereas the triclosan compound and the four iodophors did not. A hexachlorophene compound applied as a foam demonstrated excellent bacteriocidal and bacteriostatic action, was less time-consuming and easier to use than compounds applied as scrubs, and did not alter a low (0.47 per cent) in-use infection rate over a period of three years.