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1.
BMC Ecol ; 20(1): 45, 2020 08 03.
Artículo en Inglés | MEDLINE | ID: mdl-32746816

RESUMEN

BACKGROUND: In this multidisciplinary study we present soil chemical, phytochemical and GIS spatial patterning evidence that fairy circles studied in three separate locations of Namibia may be caused by Euphorbia species. RESULTS: We show that matrix sand coated with E. damarana latex resulted in faster water-infiltration rates. GC-MS analyses revealed that soil from fairy circles and from under decomposing E. damarana plants are very similar in phytochemistry. E. damarana and E. gummifera extracts have a detrimental effect on bacteria isolated from the rhizosphere of Stipagrostis uniplumis and inhibit grass seed germination. Several compounds previously identified with antimicrobial and phytotoxic activity were also identified in E. gummifera. GIS analyses showed that perimeter sizes and spatial characteristics (Voronoi tessellations, distance to nearest neighbour ratio, pair correlation function and L-function) of fairy circles are similar to those of fairy circles co-occurring with E. damarana (northern Namibia), and with E. gummifera (southern Namibia). Historical aerial imagery showed that in a population of 406 E. gummifera plants, 134 were replaced by fairy circles over a 50-year period. And finally, by integrating rainfall, altitude and landcover in a GIS-based site suitability model, we predict where fairy circles should occur. The model largely agreed with the distribution of three Euphorbia species and resulted in the discovery of new locations of fairy circles, in the far southeast of Namibia and part of the Kalahari Desert of South Africa. CONCLUSIONS: It is proposed that the allelopathic, adhesive, hydrophobic and toxic latex of E. damarana, E. gummifera, and possibly other species like E. gregaria, is the cause of the fairy circles of Namibia in the areas investigated and possibly in all other areas as well.


Asunto(s)
Euphorbia , Adhesivos , Látex , Namibia , Suelo
2.
Nat Commun ; 11(1): 3895, 2020 08 04.
Artículo en Inglés | MEDLINE | ID: mdl-32753588

RESUMEN

The mussel byssus has long been a source of inspiration for the adhesion community. Recently, adhesive synergy between flanking lysine (Lys, K) and 3,4-Dihydroxyphenylalanine (DOPA, Y) residues in the mussel foot proteins (Mfps) has been highlighted. However, the complex topological relationship of DOPA and Lys as well as the interfacial adhesive roles of other amino acids have been understudied. Herein, we study adhesion of Lys and DOPA-containing peptides to organic and inorganic substrates using single-molecule force spectroscopy (SMFS). We show that a modest increase in peptide length, from KY to (KY)3, increases adhesion strength to TiO2. Surprisingly, further increase in peptide length offers no additional benefit. Additionally, comparison of adhesion of dipeptides containing Lys and either DOPA (KY) or phenylalanine (KF) shows that DOPA is stronger and more versatile. We furthermore demonstrate that incorporating a nonadhesive spacer between (KY) repeats can mimic the hidden length in the Mfp and act as an effective strategy to dissipate energy.


Asunto(s)
Adhesivos/química , Dihidroxifenilalanina/química , Lisina/química , Secuencia de Aminoácidos , Animales , Bivalvos , Dipéptidos , Péptidos/síntesis química , Propiedades de Superficie , Titanio/química
3.
Sci Total Environ ; 738: 140357, 2020 Oct 10.
Artículo en Inglés | MEDLINE | ID: mdl-32806374

RESUMEN

The wood panel industry requires the introduction of more environmental-friendly adhesives due to the strict current regulations on formaldehyde-based emissions. The purpose of this study was to environmentally analyse the production of four different bio-adhesives as alternatives to the most conventional fossil resins used in the production of wood panels. The bio-adhesives proposed for analysis derived from different available renewable biopolymers such as protein (soy) and lignin (Kraft and Organosolv), as well as tannin. The production systems were evaluated from a cradle-to-gate perspective using the Life Cycle Assessment methodology, with the aim of identifying critical parameters and comparing them with fossil substitutes. Inventory data of bio-adhesives were modelled at large scale from lab scale experiments and completed with literature reports. Our results showed that the soy-based and tannin based bio-adhesive had an overall better profile than fossil resins, identifying the production of polyacrylamide for the former, and the production of condensed tannin and glyoxal for the latter, as the main environmental hotspots. In contrast, further research is required on the use of lignins, specifically because of the electricity requirements in the lignin glyoxalation stage (a process required for the functionalization of lignin). Sensitivity analyses were conduced on these key parameters suggesting that there is room for improvement.This study provides useful information for researchers and policy-makers on where to focus their activities with the aim of making the future of bio-adhesives more technically and environmentally favourable.


Asunto(s)
Adhesivos , Madera , Formaldehído , Industrias , Lignina
4.
Hu Li Za Zhi ; 67(4): 81-88, 2020 Aug.
Artículo en Chino | MEDLINE | ID: mdl-32748382

RESUMEN

BACKGROUND & PROBLEMS: Medical adhesives are typically used to fix wound dressings and catheters in place. Medical adhesive-related skin injuries (MARSI) are frequently caused by repetitive or improper usage of these products. The incidence rate in this unit is as high as 12.5%, which increases the difficulty and cost of care. After analysis of the situation, we identified the main causes of MARSI in our unit as: (1) Inadequate use of medical-adhesive products, (2) Lack of relevant education and training to prevent MARSI, and (3) lack of a standardized skin-damage-care procedure. PURPOSE: To decrease the incidence of MARSI in the pediatric intensive care unit. RESOLUTIONS: A training program was enacted to teach proper medical-adhesive application and removal techniques to caregivers. Consensus on care procedures was reached and care standards were modified. A mechanism for quality control was established. RESULTS: After implementing the program, the incidence of MARSI dropped from 12.5% to 5.18%, which achieved the target of this project. CONCLUSIONS: Other caregivers at our institution remain unaware of MARSI prevention techniques and protocols. We plan to continue cooperating with other staff members to prevent MARSI and to continue to reduce related skin injuries to as close to nil as possible.


Asunto(s)
Adhesivos/efectos adversos , Unidades de Cuidado Intensivo Pediátrico , Personal de Enfermería en Hospital/educación , Cuidados de la Piel/enfermería , Piel/lesiones , Niño , Humanos , Incidencia , Investigación en Evaluación de Enfermería
5.
J Adhes Dent ; 22(4): 393-398, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32666065

RESUMEN

PURPOSE: To assess the effect of the application of different electric currents on dentin bonding and resin infiltration of self-etching and etch-and-rinse adhesives. MATERIALS AND METHODS: Two hundred four sound third molars were selected and divided in groups according to the adhesive (self-etch [CSE, Clearfil SE Bond, Kuraray Noritake], universal [SBU, Single Bond Universal, 3M Oral Care], and etch-and-rinse [SB2, Adper Single Bond 2 (SB2), 3M Oral Care]) and electrical current used (0, 5, 10, 15, 20, 25, 30, and 35 µA). Light curing was performed for 10 s with an LED-curing unit at 1000 mW/cm2. Composite blocks were constructed of nanofilled composite in increments of 2 mm, which were light cured for 20 s. Specimens were sectioned into sticks with a cross-sectional area of ~1 mm2 and stored in distilled water at 37°C for 24 h. Microtensile bond strength (µTBS) testing (n = 8) was performed using a universal testing machine at a crosshead speed of 0.5 mm/min until failure. The bonding quality (n = 2) of adhesives applied with or without 35-µA electric current was evaluated using confocal laser scanning microscopy. Bond strengths were analyzed with two-way ANOVA and Tukey's test (α = 0.05). RESULTS: CSE presented the highest µTBS for all electrical currents tested. For CSE and SBU, electrical currents from 0-20 µA showed the lowest µTBS. Electrical currents from 0-10 and 20-25 µA yielded the lowest µTBS for SB2. CSE and SB2 applied under 35 µA showed a greater number of resin tags in dentin tubules. Fluorescein penetration into the hybrid layer was found for SBU applied without electric current. CONCLUSION: The application of adhesives using 35-µA electric current improved the bond strength and quality of the adhesive interface.


Asunto(s)
Recubrimiento Dental Adhesivo , Recubrimientos Dentinarios , Adhesivos , Resinas Compuestas , Dentina , Ensayo de Materiales , Cementos de Resina , Resistencia a la Tracción
6.
Zhongguo Gu Shang ; 33(7): 662-4, 2020 Jul 25.
Artículo en Chino | MEDLINE | ID: mdl-32700492

RESUMEN

OBJECTIVE: To observe clinical efficacy of back arm flexion and extension combined with manipulation in treating adhesive scapulohumeral periarthritis. METHODS: From March 2016 to April 2018, 53 patients with adhesive scapulohumeral periarthritis were treated with back arm flexion and extension combined with manipulation, the main symptoms were shoulder pain and limited activity. There were 22 males and 31 females aged from 45 to 71 years old with an average of (51.63±5.79) years;the courses of disease ranged from 3 to 24 months with an average of (8.62±3.73) months. Manipulation treatment was carried out once a week, and back arm flexion and extension were performed for 3 times a day with15 movements each time, totally 4 weeks for a single course. Visual analogue scale (VAS) and Constant-Murley shoulder function score were observed and compared before treatment and one week, one and three months after treatment. RESULTS: All patients were followed up from 3 to 12 months, with an average of (5.91±3.55) months. VAS score before treatment was 4.02±1.46, and was improved to 3.15±1.54, 1.98±1.37, 1.12±0.86 respectively at one week, one and three months after treatment. Constant-Murley score before treatment was 42.70 ±5.72, and improved to 54.25 ±6.34, 67.45 ±6.84, 82.40 ±6.63 at one week, one and three months after treatment respectively;19 patients got excellent result, 22 good, 9 fair and 3 poor. CONCLUSION: Back arm flexion combined with manipulation for the treatment of adhesive scapulohumeral periarthritis could effectively relieve pain, improve shoulder function, which is a simple effective treatment strategy.


Asunto(s)
Terapia por Acupuntura , Periartritis , Puntos de Acupuntura , Adhesivos , Brazo , Preescolar , Femenino , Humanos , Lactante , Masculino , Resultado del Tratamiento
7.
Niger J Clin Pract ; 23(6): 792-797, 2020 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-32525113

RESUMEN

Background: There is no information about the shear bond strengths (SBS) of zirconia ceramic to primary tooth dentin. Aim: To investigate the effect of different surface treatments and cements on the shear bond strength (SBS) of zirconia ceramic to primary tooth dentin. Materials and Methods: Prepared zirconia bars were distributed into four groups according to surface treatment procedure: control, sandblasting, CoJet and hot etching. The zirconia specimens in each group were further divided into subgroups according to cement (n = 13): self-adhesive resin (Rely-X Unicem), resin-modified glass ionomer (Ketac-Cem Plus), and universal bioactive (BioCem). Zirconia specimens were bonded to the primary tooth dentin surface by cement. SBS was measured, and the data were subjected to two-way ANOVA and Tukey's tests. Results: Statistical differences were observed in the surface treatment procedures for Rely-X Unicem (P < 0.05), but no statistically significant differences were found in the sandblasting, CoJet and hot-etching groups for Ketac-Cem Plus (P > 0.05). For BioCem, the SBS value for the hot etching group was significantly lower than those for the CoJet and sandblasting groups (P < 0.05). The SBS values for the Rely-X Unicem subgroups (sandblasting, CoJet and hot etching) were significantly higher than those for the other cements (P < 0.05). Conclusion: The bond strength of zirconia ceramic to primary tooth dentin is affected by surface treatments and cements.


Asunto(s)
Cerámica/química , Recubrimiento Dental Adhesivo , Dentina , Cementos de Resina/química , Resistencia al Corte , Diente Primario , Circonio/química , Resinas Acrílicas , Adhesivos , Cementos de Ionómero Vitreo , Humanos , Ensayo de Materiales , Dióxido de Silicio , Propiedades de Superficie
8.
J Biomed Nanotechnol ; 16(3): 263-282, 2020 Mar 01.
Artículo en Inglés | MEDLINE | ID: mdl-32493539

RESUMEN

Suturing has been the gold standard approach to close wounds for many decades. However, suturing causes tissue damage, which is accompanied by foreign body reaction, entry of pathogens, complications, infection, or death. In addition, the procedure is usually time-consuming, requiring manual dexterity and free moving space. Other adhesive approaches have been proposed and demonstrated with great potential, including laser-assisted tissue closure with either photothermal or photochemical reactions, application of nanoparticles, glues, constructs based on extracellular matrix (ECM), microbarbs, bio-inspired structures, and tape. The quality of closure has been evaluated by histological methods, indexing, morphology, tensile testing, patency rate, leakage pressure, and burst pressure. All the novel tissue joining methods aim to provide an adhesive with appropriate strength, non-cytotoxicity, and minimal damage. The capability for rapid attachment and release may further reduce surgical procedure time. More research is needed to prove the feasibility of new tissue joining techniques based on the type of tissue, surface chemistry, and working environment.


Asunto(s)
Nanopartículas , Adhesivos Tisulares , Adhesivos , Matriz Extracelular , Rayos Láser
9.
Anticancer Res ; 40(5): 2801-2812, 2020 May.
Artículo en Inglés | MEDLINE | ID: mdl-32366427

RESUMEN

BACKGROUND/AIM: The influence of a polyurethane-based tissue adhesive (TissuGlu®) on common complications following breast surgery was investigated. PATIENTS AND METHODS: Within a Randomized-Controlled-Trial 70 women (n=35 TissuGlu®, n=35 drain) underwent a mastectomy with or without sentinel lymph node excision (SLNE), followed by a 90-day postoperative follow-up. RESULTS: Postoperative interventions: Non-inferiority of the application of TissuGlu® was seen. Pain-Level/ Hospitalization: A statistically significant pain reduction from day four onwards (p<0.001) and a shorter hospitalization period (p<0.001) was observed. In contrast, the TissuGlu® group showed increased mean puncture incidence (p=0.013), and increased puncture volume (p=0.021). CONCLUSION: Application of the polyurethane-based tissue adhesive TissuGlu® after mastectomy, with or without SLNE, showed potential for improvement of the clinical outcome. In contrast, high intervention rates and increased puncture volume, caused by recurring seromas following application of the surgical adhesive TissuGlu®, have a negative impact on the patient-specific convalescence.


Asunto(s)
Adhesivos/efectos adversos , Lisina/efectos adversos , Mastectomía/efectos adversos , Uretano/efectos adversos , Femenino , Humanos , Mastectomía/métodos , Periodo Posoperatorio , Estudios Prospectivos , Estudios Retrospectivos , Resultado del Tratamiento
10.
AAPS PharmSciTech ; 21(4): 120, 2020 Apr 22.
Artículo en Inglés | MEDLINE | ID: mdl-32323091

RESUMEN

The objective of this study was to develop a simpler and more practical quantitative evaluation method of cold flow (CF) in transdermal drug delivery systems (TDDSs). CF was forcibly induced by loading a weight on a punched-out sample (bisoprolol and tulobuterol tapes). When the extent of CF was analyzed using the area of oozed adhesive as following a previously reported method, the CF profiles were looked different between the samples 12 mm in diameter subjected to a 0.5-kg weight and samples 24 mm in diameter subjected to a 2.0-kg weight despite an equal load per unit area (4.42 g/mm2). The width of oozed adhesive around the original sample was suggested to be an index that properly describes the relationship between the load per unit area and the extent of CF. Further, it was clarified that the average CF width over the entire circumference of the sample was the same whether the samples were round or square as long as the sample area and load were the same. We also observed a linear relationship between the CF width and the aspect ratio of oval and rectangular samples. These results indicated that the CF properties of typical TDDS products lacking CF-proof processing at the edges could be determined by testing samples cut from the product rather than the whole TDDS patch. The proposed width measuring method was simple and useful for optimizing the composition of the adhesive and for testing the quality of the product.


Asunto(s)
Adhesivos/farmacocinética , Frío , Sistemas de Liberación de Medicamentos/métodos , Terbutalina/análogos & derivados , Adhesivos/administración & dosificación , Adhesivos/química , Administración Cutánea , Agonistas Adrenérgicos beta/administración & dosificación , Agonistas Adrenérgicos beta/química , Agonistas Adrenérgicos beta/farmacocinética , Evaluación Preclínica de Medicamentos/métodos , Terbutalina/administración & dosificación , Terbutalina/química , Terbutalina/farmacocinética
11.
Biofouling ; 36(3): 245-255, 2020 03.
Artículo en Inglés | MEDLINE | ID: mdl-32326753

RESUMEN

Dental plaque is a biofilm composed of a complex oral microbial community. The accumulation of plaque in the pit and fissures of dental elements often leads to the development of tooth decay (dental caries). Here, potent anti-biofilm materials were developed by incorporating zinc methacrylates or di-n-butyl-dimethacrylate-tin into the light-curable sealant and their physical, mechanical, and biological properties were evaluated. The data revealed that 5% di-n-butyl-dimethacrylate-tin (SnM 5%) incorporated sealant showed strong anti-biofilm efficacy against various single-species (Streptococcus mutans or Streptococcus oralis or Candida albicans) and S. mutans-C. albicans cross-kingdom dual-species biofilms without either impairing the mechanical properties of the sealant or causing cytotoxicities against mouse fibroblasts. The findings indicate that the incorporation of SnM 5% in the experimental pit and fissure self-adhesive sealant may have the potential to be part of current chemotherapeutic strategies to prevent the formation of cariogenic oral biofilms that cause dental caries.


Asunto(s)
Adhesivos/farmacología , Biopelículas/efectos de los fármacos , Caries Dental/prevención & control , Selladores de Fosas y Fisuras/farmacología , Zinc/química , Adhesivos/química , Animales , Biopelículas/crecimiento & desarrollo , Candida albicans/efectos de los fármacos , Candida albicans/crecimiento & desarrollo , Caries Dental/microbiología , Humanos , Metacrilatos/química , Ratones , Microbiota/efectos de los fármacos , Selladores de Fosas y Fisuras/química , Streptococcus mutans/efectos de los fármacos , Streptococcus mutans/crecimiento & desarrollo , Streptococcus oralis/efectos de los fármacos , Streptococcus oralis/crecimiento & desarrollo
12.
PLoS One ; 15(4): e0231619, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32294117

RESUMEN

BACKGROUND: Tendinopathy is a common musculoskeletal disorder and current treatment options show limited success. Genipin is an effective collagen crosslinker with low cytotoxicity and a promising therapeutic strategy for stabilizing an intratendinous lesion. PURPOSE: This study examined the mechanical effect and delivery of intratendinous genipin injection in healthy and degenerated tendons. STUDY DESIGN: Controlled laboratory study. METHODS: Bovine superficial digital flexor tendons were randomized into four groups: Healthy control (N = 25), healthy genipin (N = 25), degenerated control (N = 45) and degenerated genipin (N = 45). Degeneration was induced by Collagenase D injection. After 24h, degenerated tendons were subsequently injected with either 0.2ml of 80mM genipin or buffer only. 24h post-treatment, samples were cyclically loaded for 500 cycles and then ramp loaded to failure. Fluorescence and absorption assays were performed to analyze genipin crosslink distribution and estimate tissue concentration after injection. RESULTS: Compared to controls, genipin treatment increased ultimate force by 19% in degenerated tendons (median control 530 N vs. 633 N; p = 0.0078). No significant differences in mechanical properties were observed in healthy tendons, while degenerated tendons showed a significant difference in ultimate stress (+23%, p = 0.049), stiffness (+27%, p = 0.037), work to failure (+42%, p = 0.009), and relative stress relaxation (-11%, p < 0.001) after genipin injection. Fluorescence and absorption were significantly higher in genipin treated tendons compared to control groups. A higher degree of crosslinking (+45%, p < 0.001) and a more localized distribution were observed in the treated healthy compared to degenerated tendons, with higher genipin tissue concentrations in healthy (7.9 mM) than in degenerated tissue (2.3 mM). CONCLUSION: Using an ex-vivo tendinopathy model, intratendinous genipin injections recovered mechanical strength to the level of healthy tendons. Measured by genipin tissue distribution, injection is an effective method for local delivery. CLINICAL RELEVANCE: This study provides a proof of concept for the use of intratendinous genipin injection in the treatment of tendinopathy. The results demonstrate that a degenerated tendon can be mechanically augmented by a clinically viable method of local genipin delivery. This warrants further in vivo studies towards the development of a clinically applicable treatment based on genipin.


Asunto(s)
Adhesivos/administración & dosificación , Colágeno/efectos de los fármacos , Iridoides/administración & dosificación , Tendinopatía/tratamiento farmacológico , Tendones/efectos de los fármacos , Animales , Bovinos , Colágeno/metabolismo , Humanos , Inyecciones Intralesiones , Tendinopatía/patología , Tendones/patología , Resistencia a la Tracción
13.
Br J Nurs ; 29(8): S28-S33, 2020 Apr 23.
Artículo en Inglés | MEDLINE | ID: mdl-32324466

RESUMEN

The use of sutureless, adhesive securement devices in vascular access has become recommended as best practice, because they are a cost-effective, reliable solution. After a vascular access device has been inserted, catheter securement is one of the most important aspects of care and maintenance. The Grip-Lok® range offers secure, comfortable adhesive securement for all types of vascular access devices. The products use hypoallergenic medical adhesive, which reduces the risk of skin irritation and provides a reliable, adaptable alternative to suturing.


Asunto(s)
Adhesivos , Cateterismo Venoso Central/instrumentación , Cateterismo Periférico/instrumentación , Dispositivos de Acceso Vascular , Cateterismo Venoso Central/métodos , Cateterismo Periférico/métodos , Diseño de Equipo , Humanos
15.
AAPS PharmSciTech ; 21(3): 97, 2020 Mar 03.
Artículo en Inglés | MEDLINE | ID: mdl-32128636

RESUMEN

Budesonide is a glucocorticoid for the treatment of ulcerative colitis (UC). The current study aims to develop a thermosensitive in situ and adhesive gel for rectal delivery of budesonide. HPMC K4M was selected as the adhesive agent based on the adhesive force and the effect on gel performance. The formulation of gel was optimized by using the central composite design-response surface methodology (CCD-RSM); a mathematical model was successfully developed to predict desired formulations as well as to analyze relationships between the amount of Pluronic F-127, Pluronic F-68, and HPMC K4M and the performances of gel. Based on CCD-RSM, a thermosensitive in situ and adhesive gel consisting of 0.002% budesonide, 0.74% HPMC, 4.87% F-68, and 19.0% F-127 was developed. Furthermore, the in vivo behavior of gel was evaluated in Sprague-Dawley rats. In comparison with budesonide solution, rectal administration of budesonide gel at 0.1 mg/kg in rats showed relative bioavailability of 230% with significant increase in rectum uptake.


Asunto(s)
Adhesivos/administración & dosificación , Antiinflamatorios/administración & dosificación , Budesonida/administración & dosificación , Sistemas de Liberación de Medicamentos/métodos , Adhesivos/metabolismo , Administración Rectal , Animales , Antiinflamatorios/metabolismo , Disponibilidad Biológica , Budesonida/metabolismo , Evaluación Preclínica de Medicamentos/métodos , Femenino , Geles , Masculino , Poloxámero/administración & dosificación , Poloxámero/metabolismo , Ratas , Ratas Sprague-Dawley , Recto/efectos de los fármacos , Recto/metabolismo
16.
Dent Mater J ; 39(4): 571-576, 2020 Aug 02.
Artículo en Inglés | MEDLINE | ID: mdl-32115488

RESUMEN

The purpose of this study was to evaluate the effects of commercialized denture adhesives and mouth moisturizers using direct and indirect cell cultures for in vitro examinations with human fibroblast and epithelial cells. Denture adhesives (Faston, Poligrip Powder, New Poligrip Free, Tafugurippu Kurimu, Polident Adhesive, Tafugurippu Tomei) and mouth moisturizers (Concool Mouth Gel, Biotene Oral Balance Gel) were subjected to live and dead detection and pH level determination. The mouth moisturizers showed higher cytotoxicity effects comparing with control on every cell cultures and cells, and pH level did not show any significant differences. However, there was no correlation of type of denture adhesive or mouth moisturizer with cytotoxicity. We concluded that cytotoxicity affects human cells regardless of type of material, though some dependence was noted.


Asunto(s)
Retención de Dentadura , Queratinocitos , Adhesivos , Cementos Dentales , Fibroblastos , Humanos , Boca
17.
Dent Mater J ; 39(4): 616-623, 2020 Aug 02.
Artículo en Inglés | MEDLINE | ID: mdl-32115491

RESUMEN

This study aimed to determine the role of the 10-methacryloyloxydecyl dihydrogen phosphate (MDP) in dentin bond durability of universal adhesive in etch-&-rinse mode through bond strength tests after different degradation conditions. This study used the MDP-containing universal adhesive, Clearfil Universal Bond Quick (CU), and an experimental adhesive (NM) made with the same ingredients as CU, excluding MDP. Shear bond strength (SBS) to dentin were obtained in etch-&-rinse mode with or without MDP. CU in self-etch mode was used as a comparison. The groups were divided into three types: 1) subjected to thermal cycling; 2) subjected to long-term water storage; and 3) stored in water for 24 h, as a baseline. The discrepancies in the mean SBS of the CU and NM groups become prominent with prolonged degradation periods. This study indicates that the MDP in universal adhesive might play a key role in enhancing dentin bond quality even when etch-&-rinse mode is used.


Asunto(s)
Recubrimiento Dental Adhesivo , Recubrimientos Dentinarios , Adhesivos , Cementos Dentales , Dentina , Ensayo de Materiales , Metacrilatos , Cementos de Resina
18.
Georgian Med News ; (298): 144-147, 2020 Jan.
Artículo en Ruso | MEDLINE | ID: mdl-32141868

RESUMEN

Oral applications of peroxidised sunflower oil (PSO) cause development of nephropathy, which can be prevented with the help of oral applications of the Biotrit phytogel containing bioflavonoids from wheat seedlings. The purpose of this work was to determine the renoprotective effect of the Biotrit phytogel under the influence of PSO on rats. The experiments were carried out on 18 white Wistar rats (females, 4-5 months, 210±12 g), divided into 3 equal groups: the first - control, received compound feed. The 2nd and 3rd groups received the same diet; however, they additionally undergo oral applications of PSO at a dose of 0.5 ml per rat daily for 5 days. Rats of the 3rd group 30 minutes before the application of PSO received application of the "Biotrit" gel in a dose of 0.5 ml per rat for 5 days. After euthanasia of animals, kidneys were removed on the 6th day and the level of biochemical markers of inflammation and the content of malonic dialdehyde (MDA), urease and lysozyme were determined in the homogenate of the latter. Under the action of PSO both indicators significantly increase: elastase activity by 20%, and MDA content by 50%. Oral applications of the "Biotrit" gel reduce both indicators of inflammation. Catalase activity does not change both with the introduction of PSO and after application of the Biotrit gel. In rats treated with PSO, urease activity in the kidneys significantly increases, indicating an increase in bacterial contamination, which decreases under the influence of oral applications of the Biotrit gel. The consumption of peroxidised fats causes the development of nephropathy in experimental animals. To prevent the development of peroxide nephropathy, one can use oral applications of "Biotrit" phytogel.


Asunto(s)
Adhesivos , Geles/administración & dosificación , Riñón/efectos de los fármacos , Extractos Vegetales/administración & dosificación , Aceite de Girasol/administración & dosificación , Administración Oral , Animales , Femenino , Geles/uso terapéutico , Oxidación-Reducción , Extractos Vegetales/uso terapéutico , Ratas , Ratas Wistar , Aceite de Girasol/uso terapéutico
19.
Wiad Lek ; 73(1): 83-86, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32124812

RESUMEN

OBJECTIVE: The aim: To study the possibilities of ultrasound in adhesive ileus obstruction diagnosis and indications for surgical treatment determination. PATIENTS AND METHODS: Materials and methods: The results of diagnosis and treatment of 60 patients with acute adhesive intestinal obstruction with comparative use of X-ray and ultrasound methods were analyzed. RESULTS: Results: The use of a standard X-ray examination of the abdominal organs upon admission to the hospital allowed the diagnosis of acute adhesions of small bowel obstruction in only 32 (53.3%) patients. Transabdominal ultrasonography allowed the establishment of adhesive ileus during hospitalization in 53 (88.3%) patients and also in 7 (11.7%) during a dynamic examination 2-3 hours after admission. Due to the lack of positive effect from the conducted conservative therapy relying on the data of ultrasound studies, 33 (55%) patients were operated on. During X-ray examination, only 10 (30.3%) of these patients demonstrated negative X-ray dynamics, and with an ultrasound study, deterioration of echo pictures was observed in all 33 (100%) patients. CONCLUSION: Conclusions: Compared with the X-ray method, transabdominal ultrasonography is established to be safe, affordable, simpler, non-invasive and highly informative method for the study of acute adhesions of the small intestinal obstruction. The method allows the assessment of the ongoing conservative therapy dynamics and determination for surgical treatment indications.


Asunto(s)
Obstrucción Intestinal , Adhesivos , Humanos , Intestino Delgado , Adherencias Tisulares , Ultrasonografía
20.
Br J Nurs ; 29(6): S20-S26, 2020 Mar 26.
Artículo en Inglés | MEDLINE | ID: mdl-32207648

RESUMEN

The skin's main function is to act as a physical barrier against harmful substances. Medical adhesive-related skin injury (MARSI) is a prevalent and under-reported condition that compromises the skin's integrity. Repeated applications and removal of appliances can increase the likelihood of MARSI occurring. Prevention and treatment are key to ensure appropriate skin preparation, product appliance and removal. The use of structured approaches is imperative and there is a need to increase the awareness of MARSI among patients and health professionals to ensure that informed decisions are made.


Asunto(s)
Adhesivos/efectos adversos , Piel/lesiones , Humanos , Fenómenos Fisiológicos de la Piel
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