Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 18.373
Filtrar
1.
Sensors (Basel) ; 24(11)2024 Jun 06.
Artículo en Inglés | MEDLINE | ID: mdl-38894473

RESUMEN

Sign language is an essential means of communication for individuals with hearing disabilities. However, there is a significant shortage of sign language interpreters in some languages, especially in Saudi Arabia. This shortage results in a large proportion of the hearing-impaired population being deprived of services, especially in public places. This paper aims to address this gap in accessibility by leveraging technology to develop systems capable of recognizing Arabic Sign Language (ArSL) using deep learning techniques. In this paper, we propose a hybrid model to capture the spatio-temporal aspects of sign language (i.e., letters and words). The hybrid model consists of a Convolutional Neural Network (CNN) classifier to extract spatial features from sign language data and a Long Short-Term Memory (LSTM) classifier to extract spatial and temporal characteristics to handle sequential data (i.e., hand movements). To demonstrate the feasibility of our proposed hybrid model, we created a dataset of 20 different words, resulting in 4000 images for ArSL: 10 static gesture words and 500 videos for 10 dynamic gesture words. Our proposed hybrid model demonstrates promising performance, with the CNN and LSTM classifiers achieving accuracy rates of 94.40% and 82.70%, respectively. These results indicate that our approach can significantly enhance communication accessibility for the hearing-impaired community in Saudi Arabia. Thus, this paper represents a major step toward promoting inclusivity and improving the quality of life for the hearing impaired.


Asunto(s)
Aprendizaje Profundo , Redes Neurales de la Computación , Lengua de Signos , Humanos , Arabia Saudita , Lenguaje , Gestos
2.
Med Sci Monit ; 30: e944352, 2024 Jun 19.
Artículo en Inglés | MEDLINE | ID: mdl-38894516

RESUMEN

BACKGROUND The use of herbal medicines (HMs) is increasing, which raises concerns of herb-drug interactions (HDIs). This questionnaire-based study aimed to evaluate knowledge of HMs and HDIs in 147 undergraduate nursing students in Riyadh, Saudi Arabia, between March 2022 to June 2022. MATERIAL AND METHODS An online cross-sectional study was conducted among 147 nursing undergraduates at King Saud University, Riyadh, Saudi Arabia from March 2022 to June 2022, using a self-administered 24-item questionnaire. The convenience sampling method was used to evaluate the knowledge of HMs and interactions of anticoagulants, anti-inflammatory drugs, antibiotics, and antiplatelet drugs with herbs like ginkgo biloba, St. John's wort, garlic, ginger, green tea, and chamomile tea. RESULTS The findings of this study reported that 74.8% of the undergraduates used HMs. With regard to HDIs, 20.4% of nursing undergraduates identified the interaction between gingko biloba and drugs like ibuprofen and warfarin, while 13.6% identified interactions between drugs like warfarin with green tea, ginger, and chamomile tea. Regarding general knowledge, 59% of the students (n=84) reported good knowledge of HMs. Previous history of HM use significantly affected the mean HM knowledge score (t=4.635; P=0.0001). CONCLUSIONS To summarize, Saudi nursing students showed a lack of understanding and knowledge of HDIs. Ability to identify specific HDIs, like ginkgo biloba interactions with warfarin and ibuprofen, and warfarin interactions with green tea and ginger, was limited. There is a need to introduce HM and HDI courses in the academic curriculum.


Asunto(s)
Interacciones de Hierba-Droga , Estudiantes de Enfermería , Humanos , Arabia Saudita , Estudios Transversales , Femenino , Masculino , Encuestas y Cuestionarios , Adulto Joven , Adulto , Conocimientos, Actitudes y Práctica en Salud , Medicina de Hierbas/métodos
3.
J Otolaryngol Head Neck Surg ; 53: 19160216241248668, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38888948

RESUMEN

BACKGROUND: To assess the risk of depression in patients with chronic rhinosinusitis (CRS) in a tertiary care center and the effect of treatment on depression scores. METHODS: This prospective cohort study was conducted at King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia, between November 2021 and June 2022 and included adult patients (≥14 years) with CRS. The validated Arabic or English Sinonasal Outcome Test (SNOT-22) and Patient Health Questionnaire-9 (PHQ-9) were used before treatment and 3 to 6 months after surgery and maximal medical treatment. PHQ-9 scores were compared at baseline and follow-up visits. The relationship between changes in SNOT-22 and PHQ-9 scores were assessed using Spearman's correlation and simple linear regression. RESULTS: Overall, 38 participants with a mean ± SD age of 32.7 ± 12 years were enrolled. CRS with nasal polyps (55.26%) was the most frequently seen condition, followed by allergic fungal CRS (31.58%) and CRS without nasal polyps (13.16%). Six patients (15.7%) had PHQ-9 scores ≥10, indicating they had major depressive disorder. PHQ-9 and SNOT-22 scores improved significantly after treatment (3.7 ± 5.8 vs 6.5 ± 6.9 pretreatment, P = .001; 20.7 ± 20.5 vs 45.6 ± 28.9 pretreatment, P < .0001, respectively). Mean ± SD change in PHQ-9 and SNOT-22 scores was -2.7 ± 7 and -24.9 ± 29.8, respectively. SNOT-22 and PHQ-9 scores were positively correlated (r = .522, P < .001). PHQ-9 score change was significantly associated with SNOT-22 score change (ß = .178, 95% confidence interval 0.12-0.23, P < .0001). CONCLUSION: CRS affects the quality of life and psychological well-being of patients. Patient-centered care with maximal medical and surgical treatment help overcome its deleterious consequences.


Asunto(s)
Rinitis , Sinusitis , Humanos , Sinusitis/complicaciones , Sinusitis/psicología , Sinusitis/terapia , Rinitis/complicaciones , Rinitis/psicología , Rinitis/terapia , Masculino , Femenino , Enfermedad Crónica , Estudios Prospectivos , Adulto , Arabia Saudita , Depresión/etiología , Depresión/diagnóstico , Persona de Mediana Edad , Prueba de Resultado Sino-Nasal , Rinosinusitis
4.
Hum Resour Health ; 22(1): 41, 2024 Jun 18.
Artículo en Inglés | MEDLINE | ID: mdl-38890735

RESUMEN

Employer of choice (EOC) is a relatively new phenomenon, particularly in Human Resources Management. Existing employees and prospective talent have reasons and expectations to designate an employer as an EOC. While EOC has received extensive attention from both academics and practitioners over the past few years, the work has mostly focused on managerial and marketing perspectives, and thus far lacks a strong theoretical foundation. Drawing on Social Exchange Theory (SET), based on Human Resources and employees' perceptions and experiences, this research aims to explore and investigate the factors that constitute/designate an employer as an Employer of Choice EOC. Two qualitative triangulated data sets were collected from existing full-time employees at a Saudi multinational corporation: open interviews and document analysis (cross-sectional and longitudinal). Thematic analysis (TA) was employed to analyze both methods. The findings reveal that company image, training, and development, satisfaction, involvement and commitment, fairness, work culture, reward, opportunities for growth, teamwork, motivation, and corporate social responsibility are the factors that lead employees to designate an employer as an EOC. This research contributes to knowledge conceptually, theoretically, and empirically, mainly in the area of Human Resources Management. This research represents one of the first studies to empirically identify and investigate employee-related factors and evaluate them all together in a multinational Saudi organization. Recognizing the findings of this empirical-based research assists HR managers in designating their organizations as an EOC for current employees and prospective talents.


Asunto(s)
Investigación Cualitativa , Humanos , Arabia Saudita , Femenino , Masculino , Estudios Transversales , Motivación , Lugar de Trabajo , Satisfacción en el Trabajo , Cultura Organizacional , Empleo , Adulto , Estudios Longitudinales , Conducta de Elección
5.
Front Endocrinol (Lausanne) ; 15: 1365714, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38872968

RESUMEN

Introduction: Hereditary Vitamin D-dependent rickets type II (HVDDR-type II) is a rare autosomal recessive disorder caused by molecular variation in the gene encoding the vitamin D receptor (VDR). This study aims to evaluate phenotype and genotype characteristics and long-term follow-up of the largest group of patients with (HVDDR-type II) in Saudi Arabia. Methodology: We conducted a retrospective chart review to collect the clinical, biochemical, and genetic data for all HVDDR-type II patients currently receiving treatment at King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia. Results: A total of 42 patients, 57.1% female, and 42.9% male were included in the study. Seven patients were treated with high doses of oral calcium, while 35 patients were treated with IV calcium infusion. The median age at presentation was 15.5 months. Alopecia was found in 97.6%, 21.4% presented with bowing legs, 14.3% with delayed walking, 9.5% with seizure, and 2.4% presented with respiratory failure, while a family history of the disease was positive in 71.4% of total patients. Molecular genetic testing of the VDR gene in our cohort identified six different gene variants c.885 C>A (p.Tyr295Ter), c.88 C>T (p.Arg30Ter), c.1036G>A (p.Val346Met), c.820C>T (p.Arg274Cys), c.803 T>C (p.Ile268Thr), and c.2T>G (p.Met1?). Conclusion: We are describing the largest cohort of patients with HVDDR-type II, their clinical biochemical findings, and the most prevalent genetic variants in our population.


Asunto(s)
Raquitismo Hipofosfatémico Familiar , Receptores de Calcitriol , Humanos , Femenino , Masculino , Arabia Saudita/epidemiología , Estudios Retrospectivos , Receptores de Calcitriol/genética , Lactante , Preescolar , Raquitismo Hipofosfatémico Familiar/genética , Raquitismo Hipofosfatémico Familiar/tratamiento farmacológico , Niño , Estudios de Seguimiento , Vitamina D/administración & dosificación , Calcio , Genotipo
6.
Front Public Health ; 12: 1387219, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38873296

RESUMEN

Despite the application of food irradiation for enhancing food safety, many consumers lack an understanding of its fundamental principles, often misinterpreting the information and exhibiting negative perceptions toward foods treated with ionizing radiation. This study focuses on evaluating public awareness regarding the consumption of irradiated food within Saudi Arabia, utilizing the Awareness Scale on Consumption of Irradiated Foods (ASCIF), a developed and validated tool. The ASCIF encompasses four constructs: concepts, awareness, labeling, and safety concerning irradiated foods. The average scores for each subscale and the aggregate ASCIF score were determined, with the analysis incorporating both descriptive and inferential statistical methods. The study's sample of 712 individuals predominantly consisted of females (53.37%), individuals aged 18-30 years (55.62%), those holding a bachelor's degree or higher (70.79%), participants earning less than SAR 5000 (42.70%), students (37.08%), and singles (66.85%). The overall mean scores for each category were as follows: safety (2.87 ± 0.92), concept (3.18 ± 0.79), label (3.44 ± 1.15), and awareness (2.68 ± 1.03). The overall mean score for the ASCIF was 3.02 ± 0.81, a diverse spectrum of awareness, with the majority of participants (62.92%) exhibiting intermediate awareness, while 17.98% displayed poor awareness, and 19.10% demonstrated high awareness. Logistic regression analysis identified age and educational attainment as significant predictors of awareness levels (p < 0.001). These results highlight a moderate understanding of irradiated foods among the Saudi population, with significant variations based on demographic factors. The study's conclusion emphasizes the necessity for tailored educational initiatives that cater to specific demographic groups to enhance understanding and awareness of irradiated food technologies in Saudi Arabia. This study thereby provides valuable insights for policymakers and health educators in designing effective communication strategies about irradiated foods.


Asunto(s)
Conocimientos, Actitudes y Práctica en Salud , Psicometría , Humanos , Arabia Saudita , Femenino , Masculino , Adulto , Adolescente , Encuestas y Cuestionarios , Irradiación de Alimentos , Adulto Joven , Inocuidad de los Alimentos , Persona de Mediana Edad , Etiquetado de Alimentos , Concienciación
7.
Front Public Health ; 12: 1411724, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38873295

RESUMEN

Introduction: Low energy availability (LEA) is a state of inadequate energy reserves that results from a negative energy balance. This condition can lead to severe health risks such as amenorrhea and osteoporosis. Various causes for LEA, such as eating disorders and exercise addiction, have been reported in the literature. However, data in Saudi Arabia are lacking. This cross-sectional study measures the prevalence of LEA, eating disorders, and exercise addiction among adult females in Saudi Arabia and identifies possible associated risk factors. Methods: The sample comprised 119 female athletes who filled out an online survey adapted from the LEA in Females Questionnaire, the Eating Disorder Examination Questionnaire, and the Exercise Addiction Inventory. Results: Participants showed a high prevalence of LEA (66.4%), eating disorder (33.6%), and exercise addiction (10.1%), confirming the association between normal weight and LEA in females living in Saudi Arabia (p < 0.00). Discussion and conclusion: With an increasing number of females in the country interested in following a healthy lifestyle, there is a need to raise the awareness of the population on the issues of LEA, eating disorders, and exercise addiction and their effects on the body by developing educational programs about energy intake and healthy physical activity routines.


Asunto(s)
Atletas , Ejercicio Físico , Trastornos de Alimentación y de la Ingestión de Alimentos , Humanos , Femenino , Arabia Saudita/epidemiología , Estudios Transversales , Atletas/estadística & datos numéricos , Adulto , Trastornos de Alimentación y de la Ingestión de Alimentos/epidemiología , Encuestas y Cuestionarios , Prevalencia , Factores de Riesgo , Adulto Joven , Ingestión de Energía , Adolescente , Conducta Adictiva/epidemiología
8.
PLoS One ; 19(6): e0302557, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38861515

RESUMEN

Abundant efforts have been directed to understand the global obesity epidemic and related obesogenic behaviors. However, the relationships of maternal concern and perception about child weight with child eating behaviors in Saudi Arabia have not been investigated. Therefore, this study aimed to examine the associations of maternal concern and perception about child overweight risk with maternal feeding practices and child eating behaviors among mothers and their children in Saudi Arabia. Mothers of 115 children aged 3-5 years old were recruited from eight preschools. Child eating behaviors (enjoyment of food, responsiveness to foods, food fussiness, satiety responsiveness, and slowness in eating) and maternal feeding practices (restriction, monitoring, and using food as a reward), maternal concern about child weight, and maternal perception about child overweight risk were assessed using validated questionnaires. Multiple linear regression models, adjusted for maternal body mass index (BMI) and child's BMI-z score and sex, were tested to examine the independent associations of maternal concern and perception about child overweight risk with child eating behaviors and maternal feeding practices. Maternal concern about child weight was positively associated with food enjoyment in children (B = 0.14 [95% confidence intervals = 0.02,0.27]) and responsiveness to food (B = 0.16 [0.03,0.29]), whereas a negative association with child food fussiness was observed (B = -0.19 [-0.33, -0.04]). Maternal perception about child overweight risk and child slowness in eating were negatively associated (B = -0.72 [-0.16 to -0.28]). Maternal concern and perception about child overweight risk were not associated with maternal feeding practices. In conclusion, maternal concern and perception about child overweight risk were found to be associated with food approach eating behavior traits but not with maternal feeding practices. Mothers who are concerned about child weight or perceive their children as overweight may need guidance and support to promote healthy eating behaviors among their children. Future cross-cultural studies are needed to understand the underlying mechanisms for the influence of maternal concern and perception about child overweight risk on maternal feeding practices, child eating behaviors, and weight status of children.


Asunto(s)
Conducta Alimentaria , Madres , Humanos , Femenino , Conducta Alimentaria/psicología , Estudios Transversales , Preescolar , Masculino , Madres/psicología , Adulto , Arabia Saudita/epidemiología , Índice de Masa Corporal , Obesidad Infantil/epidemiología , Obesidad Infantil/psicología , Obesidad Infantil/etiología , Sobrepeso/epidemiología , Sobrepeso/psicología , Percepción , Encuestas y Cuestionarios , Relaciones Madre-Hijo/psicología , Conducta Infantil/psicología
9.
Artículo en Inglés | MEDLINE | ID: mdl-38865172

RESUMEN

Two bacteria, UG2_1T and UG2_2, were isolated from the gill tissues of the mangrove fiddler crab Cranuca inversa collected on the east coast of the Red Sea (Thuwal, Saudi Arabia). The cells are Gram-negative, rod-shaped, orange-pigmented, motile by gliding with no flagella, strictly aerobic, and grow at 20-37 °C (optimum, 28-35 °C), at pH 5.0-9.0 (optimum, pH 6.0-7.0), and with 1-11 % (w/v) NaCl (optimum, 2-4 %). They were positive for oxidase and catalase activity. Phylogenetic analysis based on 16S rRNA gene sequences indicated that isolates UG2_1T and UG2_2 belong to the genus Mangrovimonas, showing the highest similarity to Mangrovimonas spongiae HN-E26T (99.4 %). Phylogenomic analysis based on the whole genomes, independently using 49 and 120 concatenated genes, showed that strains UG2_1T and UG2_2 formed a monophyletic lineage in a different cluster from other type strain species within the genus Mangrovimonas. The genome sizes were 3.08 and 3.07 Mbp for UG2_1T and UG2_2, respectively, with a G+C content of 33.8 mol% for both strains. Values of average nucleotide identity and digital DNA-DNA hybridization between the strains and closely related species were 91.0 and 43.5 %, respectively. Chemotaxonomic analysis indicated that both strains had iso-C15 : 0 and iso-C15 : 1 G as dominant fatty acids, and the primary respiratory quinone was identified as MK-6. The major polar lipids comprised phosphatidylethanolamine, one unidentified glycolipid, one unidentified phospholipid, two unidentified aminolipids, and four unidentified lipids. Based on phylogenetic, phylogenomic, genome relatedness, phenotypic, and chemotaxonomical data, the two isolates represent a novel species within the genus Mangrovimonas, with the proposed name Mangrovimonas cancribranchiae sp. nov., and the type strain UG2_1T (=KCTC 102158T=DSM 117025T).


Asunto(s)
Técnicas de Tipificación Bacteriana , Composición de Base , Braquiuros , ADN Bacteriano , Ácidos Grasos , Branquias , Hibridación de Ácido Nucleico , Filogenia , ARN Ribosómico 16S , Análisis de Secuencia de ADN , ARN Ribosómico 16S/genética , Ácidos Grasos/análisis , ADN Bacteriano/genética , Océano Índico , Animales , Branquias/microbiología , Braquiuros/microbiología , Arabia Saudita , Humedales , Vitamina K 2/análogos & derivados , Vitamina K 2/análisis , Fosfolípidos/análisis
10.
Clin Lab ; 70(6)2024 Jun 01.
Artículo en Inglés | MEDLINE | ID: mdl-38868869

RESUMEN

BACKGROUND: Improving global access to secure blood holds paramount importance for supporting medical interventions vital to saving lives. As students and professionals in the medical field are pivotal in informing and motivating the public to donate blood, this study investigated the awareness of blood donation requirements and protocols among undergraduate health sciences students at King Khalid University. METHODS: A total of 106 students participated in the study. Google Forms was used to generate the survey and to collect data, and GraphPad Prism was used to visualize and analyze the data extracted from the form. RESULTS: The study population was predominantly male (63.2% male vs. 36.8% female). Participants demonstrated a good understanding on questions pertaining to blood storage, transmitted infections, and the minimum weight requirement for donation. Divergent responses were observed regarding the optimal age for donation, minimal blood volume, fasting requirements, and the minimum interval between donations. CONCLUSIONS: The results of our study indicate a pressing need to enhance knowledge of blood donation among students in medical fields, particularly given the crucial role of health professionals in educating the public. Greater awareness will promote a greater frequency of donations and a wider dissemination of accurate information concerning blood donation protocols.


Asunto(s)
Donantes de Sangre , Conocimientos, Actitudes y Práctica en Salud , Humanos , Donantes de Sangre/psicología , Donantes de Sangre/estadística & datos numéricos , Arabia Saudita , Masculino , Femenino , Universidades , Adulto Joven , Encuestas y Cuestionarios , Estudiantes/psicología , Estudiantes/estadística & datos numéricos , Adulto , Donación de Sangre
11.
Front Public Health ; 12: 1269559, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38859901

RESUMEN

Background: Epistaxis is one of the most common ear, nose, and throat (ENT) emergencies that present to the emergency or primary care centers. Study aim: This study aimed to assess the knowledge of the Saudi general public toward epistaxis. Methods: This study adopted a cross-sectional analytical study design. The questionnaire link was distributed using social media channels. The participants were adult Saudi nationals that live in Saudi Arabia. The data was collected using a self-administered questionnaire that assessed knowledge related to epistaxis. The knowledge score was calculated using the 10 knowledge evaluation questions. Each correct response was assigned a value of "one." The scores ranged from "zero" to "ten," with higher scores signifying greater knowledge. A percentage score was computed, and the participants' knowledge was classified as poor (% score: ≤50%), moderate (% score: 51 to 70%), and good (% score: 71 to 100%). Statistical Package for Social Sciences (SPSS) version 26 was used for statistical analysis. Results: The study included 452 participants of whom 70.1% were females. Married individuals comprised 60.8% of the sample. The prevalence of self-reported epistaxis was 43.6% in the last 6 months. Among the participants, 42.9%, had "Poor" knowledge score, followed by 39.6% who had "moderate" score, and 17.5% had "Good" score. These results show that most participants had poor to moderate knowledge, with a minority demonstrating a good level of knowledge. All demographic variables have significantly influenced the adequacy of knowledge about epistaxis. Furthermore, participants who believed that the general public has insufficient knowledge on epistaxis had a significantly lower knowledge score (p = 0.001). Conclusion: The present study found a non-satisfactory, low-to-moderate knowledge level of the Saudi general public toward epistaxis. We propose emphasizing public knowledge and education about first aid for epistaxis because proper first aid can minimize significant complications when done properly.


Asunto(s)
Epistaxis , Conocimientos, Actitudes y Práctica en Salud , Humanos , Estudios Transversales , Arabia Saudita , Femenino , Masculino , Adulto , Encuestas y Cuestionarios , Persona de Mediana Edad , Adulto Joven , Adolescente
12.
J Dermatolog Treat ; 35(1): 2353693, 2024 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-38862417

RESUMEN

Purpose: There is limited information about the diagnosis and treatment of hidradenitis suppurativa (HS) in the Kingdom of Saudi Arabia (KSA). This Delphi consensus study was conducted to develop recommendations for the management of HS in the KSA.Methods: The expert panel including 12 dermatologists with extensive experience treating HS patients provided nine consensus statements and recommendations on diagnosis and assessment, management, comorbidities and multidisciplinary approach, and education. The experts also developed clinical questions pertaining to the management of HS and rolled out as a survey to 119 dermatologists practising in the KSA.Results: The topics covered included: referring physicians' awareness of HS; referral criteria for HS; definition of moderate-to-severe HS; treatment goals; definition of treatment success; treatment and biologic initiation; comorbidities and multidisciplinary approach; patient education and awareness of HS. Full consensus (100%) from the expert dermatologists was received on all the topics except referring physicians' awareness of HS, definition of treatment success, and treatment and biologic initiation. The survey results resonated with the expert opinion.Conclusion: As HS is a chronic disease with negative impact on quality-of-life, timely diagnosis and treatment, early identification of comorbid conditions and a multidisciplinary care approach are crucial for effective management of HS.


Asunto(s)
Consenso , Técnica Delphi , Hidradenitis Supurativa , Derivación y Consulta , Hidradenitis Supurativa/terapia , Hidradenitis Supurativa/diagnóstico , Humanos , Arabia Saudita , Derivación y Consulta/normas , Derivación y Consulta/estadística & datos numéricos , Índice de Severidad de la Enfermedad , Comorbilidad , Dermatólogos/normas , Dermatólogos/estadística & datos numéricos , Calidad de Vida , Educación del Paciente como Asunto/normas , Resultado del Tratamiento
13.
BMC Infect Dis ; 24(1): 576, 2024 Jun 11.
Artículo en Inglés | MEDLINE | ID: mdl-38862891

RESUMEN

BACKGROUND: The impact of COVID-19 infection on the blood system remains to be investigated, especially with those encountering hematological malignancies. It was found that a high proportion of cancer patients are at an elevated risk of encountering COVID-19 infection. Leukemic patients are often suppressed and immunocompromised, which would impact the pathology following COVID-19 infection. Therefore, this research aims to bring valuable insight into the mechanism by which COVID-19 infection influences the hematological and biochemical parameters of patients with acute leukemia. METHODS: This retrospective investigation uses repeated measures to examine changes in hematological and biochemical parameters among patients with acute leukemia before and after COVID-19 infection at a major Saudi tertiary center. The investigation was conducted at the Ministry of National Guard-Health Affairs in Riyadh, Saudi Arabia, on 24 acute leukemia patients with COVID-19 between April 2020 and July 2023. The impact of COVID-19 on clinical parameters, comorbidities, and laboratory values was evaluated using data obtained from the electronic health records at four designated time intervals. The relative importance of comorbidities, testing preferences, and significant predictors of survival was ascertained. RESULTS: The majority of leukemic COVID-19-infected patients, primarily detected through PCR tests, were diagnosed with acute lymphoblastic leukemia (70.8%). The hematological and biochemical parameters exhibited stability, except for a brief increase in ALT and a sustained rise in AST. These changes were not statistically significant, and parameters remained normal at all time points. Additionally, an increase in monocyte count was shown at time point-3, as well as platelet counts at time point 2. CONCLUSION: While this study did not detect statistically significant effects of COVID-19 on biochemical and hematological parameters in acute leukemia patients, further investigation is needed to fully understand the potential adverse reactions and modifications following COVID-19 infection.


Asunto(s)
COVID-19 , SARS-CoV-2 , Humanos , COVID-19/sangre , COVID-19/epidemiología , COVID-19/complicaciones , Masculino , Femenino , Estudios Retrospectivos , Adulto , Persona de Mediana Edad , Arabia Saudita/epidemiología , Adulto Joven , Leucemia/sangre , Leucemia/complicaciones , Leucemia-Linfoma Linfoblástico de Células Precursoras/sangre , Leucemia-Linfoma Linfoblástico de Células Precursoras/complicaciones , Anciano , Leucemia Mieloide Aguda/sangre , Leucemia Mieloide Aguda/complicaciones , Adolescente , Comorbilidad
14.
Ann Saudi Med ; 44(3): 153-160, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38853474

RESUMEN

BACKGROUND: Nasopharyngeal carcinoma (NPC) is a rare disease worldwide; To the best of our knowledge, there is no established standard of care specifically tailored for the adolescent population. The majority of existing research relies on retrospective data analysis. OBJECTIVE: Evaluate clinical features, treatment results, prognostic factors and late toxicities of locally advanced NPC patients treated with tomotherapy. DESIGN: Retrospective. SETTINGS: Tertiary care hospital. PATIENTS AND METHODS: Between January 2007 and January 2020, we treated patients with NPC, aged between 14 and 21 years, with concomitant chemoradiotherapy using tomotherapy at our institution. We prospectively collected details of clinical characteristics, treatment modalities, outcomes and prognostic factors of these patients and then analysed them retrospectively. MAIN OUTCOME MEASURES: 3-5 years overall survival (OS), 3-5 years locoregional control rate, 3-5 years disease-free survival (DFS), prognostic factors. SAMPLE SIZE: 51 patients. RESULTS: There were 26 male and 25 female patients included in our study. The mean age was 16.5 years, 5 (9.8%) patients with stage III, and 46 (90.2%) with stage IVa according to the American Joint Committee on Cancer, 8th edition staging system. Most patients (98%) received two or more cycles of induction chemotherapy. All patients received concomitant chemoradiotherapy. The median total dose of radiotherapy delivered was 6600 cGy (range 4800-7000). With a median follow-up of 73 months (range 9-168 months), a 5-year locoregional control rate, 5-year OS and 5-year DFS rates were 100%, 86.8% and 71.7%, respectively. Five years later, disease control was 71.7%. Ten (19.6%) patients had disease recurrence in the form of distant metastases during the follow up. CONCLUSIONS: Helical tomotherapy has an excellent late toxicity profile without compromising clinical outcome for patients with NPC. Radiotherapy remains the mainstay of treatment of nasopharyngeal carcinoma to achieve remarkable local control rates. LIMITATIONS: Single institution experience, small number of patients, and retrospective design.


Asunto(s)
Quimioradioterapia , Carcinoma Nasofaríngeo , Neoplasias Nasofaríngeas , Estadificación de Neoplasias , Radioterapia de Intensidad Modulada , Humanos , Femenino , Masculino , Adolescente , Carcinoma Nasofaríngeo/terapia , Carcinoma Nasofaríngeo/radioterapia , Carcinoma Nasofaríngeo/mortalidad , Carcinoma Nasofaríngeo/patología , Neoplasias Nasofaríngeas/terapia , Neoplasias Nasofaríngeas/radioterapia , Neoplasias Nasofaríngeas/patología , Estudios Retrospectivos , Radioterapia de Intensidad Modulada/métodos , Radioterapia de Intensidad Modulada/efectos adversos , Adulto Joven , Quimioradioterapia/métodos , Supervivencia sin Enfermedad , Arabia Saudita , Pronóstico , Resultado del Tratamiento , Tasa de Supervivencia , Quimioterapia de Inducción/métodos
15.
Medicine (Baltimore) ; 103(23): e38243, 2024 Jun 07.
Artículo en Inglés | MEDLINE | ID: mdl-38847689

RESUMEN

Cheating behavior is spreading among nursing students worldwide, necessitating the development of a validated questionnaire evaluating the reasons for such behavior. Nursing students (N = 482) from 2 universities in Saudi Arabia participated in this observational study. A survey containing items on socio-demographics and the 33-item Reasons for Cheating Scale (RCS) was completed by the respondents. The RCS had a 1-factor structure; the model fit indices were similar between the 1-, 2-, and 3-factor models, but the inter-factor correlations were too high for the 2- and 3-factor models. The measures of the quality of the factor score estimates were as follows: factor determinacy index, 0.987; expected a posteriori marginal reliability, 0.974; sensitivity ratio, 6.178; and expected percentage of true differences, 97.3%. The measures of the closeness to unidimensionality for the overall RCS were as follows: unidimensional congruence, 0.957; explained common variance, 0.875; and mean item residual absolute loading, 0.223. The intraclass correlation coefficient and McDonald's omega were 0.96 (CI: 0.93-0.98) and 0.962 (95% CI: 0.958-0.967), respectively. The severity score, infit, and outfit ranged from -0.847 to -2.015, 0.813 to 1.742, and 0.837 to 1.661, respectively. For all RCS items, the thresholds ranked τi1 < τi2 < τi3 < τi4 and showed invariance between the sexes. The RCS showed robust psychometric validity for both classical and item response theory parameters. It also had excellent test-retest reliability, internal consistency, item discrimination, factorial validity, measurement invariance, and ordered threshold level for the responses. Therefore, the RCS is a valid and reliable tool for assessing cheating behavior among nursing students.


Asunto(s)
Estudiantes de Enfermería , Humanos , Estudiantes de Enfermería/estadística & datos numéricos , Estudiantes de Enfermería/psicología , Femenino , Masculino , Estudios Transversales , Encuestas y Cuestionarios/normas , Arabia Saudita , Reproducibilidad de los Resultados , Adulto Joven , Adulto , Decepción , Psicometría/métodos , Adolescente
16.
East Mediterr Health J ; 30(5): 344-349, 2024 May 29.
Artículo en Inglés | MEDLINE | ID: mdl-38874293

RESUMEN

Background: Adequate supply of rehabilitation health workforce is a prerequisite for enhancing access to rehabilitation care. However, there is a lack of comprehensive data regarding the supply of rehabilitation health workers in Saudi Arabia. Aims: To determine the need for, and supply of, rehabilitation workforce, and investigate the relationship between rehabilitation workforce supply and rehabilitation needs in Saudi Arabia. Methodology: This cross-sectional study measured the ratio of physiotherapists and occupational therapists per 10 000 population. Data were obtained from the Ministry of Health, family health survey and census data of the General Authority for Statistics and published literature. To assess the need for rehabilitation services, we computed a composite disability index based on 3 variables: count of individuals with physical disabilities, those with chronic diseases, and those aged > 65 years. Determinants of the supply potential were population size, rural population percentage, and physician supply. Data were analysed using descriptive statistics and simple linear regression. Results: The ratios of physiotherapists and occupational therapists working at the Ministry of Health facilities were 0.69 and 0.03 per 10 000 population, respectively. Overall rehabilitation health workforce ratio was 0.73 per 10 000. Supply varied across regions, from 0.4 for Riyadh to 2.5 for Al Jouf. Nine regions exceeded the overall ratio. Rehabilitation need index ranged from 0.144 in Najran to 0.212 in Aseer. No significant associations were found between rehabilitation workforce supply on one hand, and need and other potential determinants on the other hand. Conclusion: The rehabilitation workforce supply in Saudi Arabia surpassed the regional and global averages, but was lower than the average for high-income countries. Workforce distribution varied by region across the country and was not related to need. It is important to consider the need for rehabilitation services and context-specific factors when determining the optimal size and distribution of the rehabilitation health workforce in Saudi Arabia.


Asunto(s)
Necesidades y Demandas de Servicios de Salud , Fuerza Laboral en Salud , Fisioterapeutas , Arabia Saudita , Humanos , Estudios Transversales , Fuerza Laboral en Salud/estadística & datos numéricos , Fisioterapeutas/provisión & distribución , Fisioterapeutas/estadística & datos numéricos , Terapeutas Ocupacionales/provisión & distribución , Terapeutas Ocupacionales/estadística & datos numéricos , Masculino , Rehabilitación/estadística & datos numéricos , Femenino , Recursos Humanos/estadística & datos numéricos
17.
Saudi Med J ; 45(6): 551-559, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38830647

RESUMEN

Vaccination is a crucial public health intervention for infection prevention. Yet, vaccine hesitation has emerged as a pressing public health concern. The objective of this review is to identify the widespread and causes of vaccine hesitancy prevalance among parents of children in Saudi Arabia. A narrative review, surveying several databases, including PubMed, PubMed Central, Scopus, Google Scholar, and relevant regional journals. We selected studies related to vaccine hesitancy prevalence and causes after removing duplicates and screening for relevance and access to full text. A total of 18 articles met the final selection criteria.The prevalence of parental vaccination reluctance in Saudi Arabia shown significant variability; ranging from 3.1-72.2%. Concerns regarding vaccine side effects appeared as the foremost reason for vaccine hesitancy. The review concluded that numerous Saudi Arabian parents still hesitate to vaccinate their children. They believe the potential adverse effects of vaccination outweigh the protective benefits against diseases.


Asunto(s)
Padres , Vacilación a la Vacunación , Vacunación , Humanos , Arabia Saudita , Padres/psicología , Vacilación a la Vacunación/psicología , Niño , Vacunación/psicología , Vacunación/efectos adversos , Conocimientos, Actitudes y Práctica en Salud
18.
Saudi Med J ; 45(6): 639-642, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38830651

RESUMEN

OBJECTIVES: To describe the current real-world treatment landscape, sequence of therapies, and outcomes in patients with prostate cancer (PC). METHODS: A retrospective cohort study for PC patients diagnosed at King Abdullah Medical City Cancer Center in Makkah, Saudi Arabia, between January 2011 and December 2021. Data extracted from electronic medical records. RESULTS: A total of 282 patients with PC, with a mean age of 70 years and body mass index of 27. Among them, 274 (99%) had no family history of cancer, while 164 (58%) had hypertension and 125 (44%) had diabetes mellitus. Adenocarcinoma was the most common histology, found in 275 (97%) patients, with 99 (35%) having a Gleason score of 9. Notably, 184 (65%) patients presented with metastatic disease, and 147 (52%) with bone metastasis. While 198 (70%) patients underwent surgery, 184 (65%) did not receive radiotherapy. The most common first-line metastatic therapy was abiraterone in 23 (8%) patients, followed by enzalutamide in 7 (2.5%). During the study period, 167 (59%) patients survived, with an average treatment duration of 2.5 years. CONCLUSION: This study provides insights into real-world treatment patterns and clinical outcomes in patients with PC. The findings of this study highlight the importance of adhering to treatment standards and making informed clinical decisions.


Asunto(s)
Neoplasias de la Próstata , Humanos , Masculino , Neoplasias de la Próstata/terapia , Neoplasias de la Próstata/patología , Arabia Saudita/epidemiología , Estudios Retrospectivos , Anciano , Persona de Mediana Edad , Resultado del Tratamiento , Feniltiohidantoína/uso terapéutico , Feniltiohidantoína/análogos & derivados , Nitrilos/uso terapéutico , Clasificación del Tumor , Adenocarcinoma/terapia , Adenocarcinoma/patología , Neoplasias Óseas/secundario , Neoplasias Óseas/terapia , Androstenos/uso terapéutico , Prostatectomía , Estudios de Cohortes , Anciano de 80 o más Años , Benzamidas
20.
Saudi Med J ; 45(6): 585-590, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38830653

RESUMEN

OBJECTIVES: To assess the prevalence of various frontal sinus fractures (FSF) and examine the relationships between these fractures, types of treatments, and potential complications. METHODS: A retrospective study was carried out in King Saud Medical City, Riyadh, Saudi Arabia. The study analyzed the records of patients who were diagnosed and treated with FSF from 2011-2021. Files with missing documents or incomplete treatment were excluded. The retrieved data includes: patients age, gender, types, locations, treatment, and complications of FSF. Data was analyzed by the statistical Package for the Social Sciences Statistics, version 23.0 using descriptive statistics and Chi-square test. RESULTS: A total of 72 cases were included, 94.4% males and 5.6% females. Road traffic accidents were the common cause of trauma (91%). Frontal sinus fractures were unilateral in 59.7% and associated other injuries in 80.6% of cases. Anterior table fractures were the largest proportion (58.3%), followed by anterior and posterior table (37.5%). The carried out surgical procedures were obliteration (23.9%), cranialization and obliteration (23.9%), and fixation only (52.2%). The post-operative complications were categorized into; neurological (22.2%), ophthalmic (15.3%), infection (2.8%), and deformity (16.7%). Anterior and posterior table had the highest percentage among these categories. CONCLUSION: Frontal sinus fractures were mostly required surgical treatment (63.9%) and post-operative complications occurred especially the neurological and ophthalmic. We recommend studies on the association of complications and different types of obliteration materials.


Asunto(s)
Accidentes de Tránsito , Seno Frontal , Fracturas Craneales , Centros de Atención Terciaria , Humanos , Arabia Saudita/epidemiología , Masculino , Estudios Retrospectivos , Femenino , Seno Frontal/lesiones , Seno Frontal/cirugía , Adulto , Fracturas Craneales/epidemiología , Fracturas Craneales/terapia , Fracturas Craneales/cirugía , Persona de Mediana Edad , Accidentes de Tránsito/estadística & datos numéricos , Incidencia , Centros de Atención Terciaria/estadística & datos numéricos , Adulto Joven , Adolescente , Complicaciones Posoperatorias/epidemiología , Anciano , Niño
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA
...