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Rev. esp. med. legal ; 50(1): 40-44, Ene.-Mar. 2024. ilus, graf
Artículo en Inglés, Español | IBECS | ID: ibc-229296


Introducción el homicidio por combinación de métodos de asfixia se observa mayoritariamente en las personas de edad avanzada o con algún impedimento físico capaz de contrarrestar la agresión. Material y métodos se realizó un estudio observacional retrospectivo sobre 634 autopsias, cinco cumplían las características de homicidios por combinación de métodos de asfixia. Resultados dos hombres y 3 mujeres, con edad promedio de 69 años, con estudios toxicológicos negativos, víctimas de un solo agresor, presentaron lesiones cutáneas periorificiales (bucales y nasales), hemorragias musculares en el tórax, fracturas costales, lesiones contusas en la cabeza, interpretadas como de sometimiento. Discusión en la combinación de métodos de asfixia, los hallazgos que deben ser vistos en conjunto son: traumatismos craneoencefálicos para someter a la víctima, lesiones cutáneas en el cuello, la cara, la cara interna de los labios, fracturas costales y lesiones por contrapresión en la espalda, los glúteos o los codos. Contextualizados en conjunto pueden explicar la dinámica de esta modalidad homicida. (AU)

Introduction Homicide by combination of suffocation methods is observed mainly in elderly people or with some physical impediment capable of counteracting the aggression. Material and methods A retrospective observational study was carried out on 634 autopsies. Five met the characteristics of homicides by combination of asphyxiation methods. Results Two men and three women, average age 69 years, with negative toxicological studies, victims of a single aggressor, presented peri orificial skin lesions (mouth and nose), muscle hemorrhages in the thorax, rib fractures, blunt injuries to the head interpreted as like submission. Discussion In the combination of asphyxia methods the findings that must be seen together: Head injuries to subdue the victim, skin lesions on the neck, face, inner face of the lips, rib fractures, and counter-pressure injuries to the back, buttocks, or elbows. Contextualized together, can explain the dynamics of this homicidal modality. (AU)

Humanos , Masculino , Femenino , Adulto Joven , Adulto , Persona de Mediana Edad , Anciano , Anciano de 80 o más Años , Homicidio/clasificación , Asfixia/mortalidad , Estenosis Esofágica/mortalidad , Patologia Forense/métodos , Argentina , Estudios Retrospectivos
BMC Public Health ; 24(1): 427, 2024 Feb 10.
Artículo en Inglés | MEDLINE | ID: mdl-38336643


BACKGROUND: Information is scarce regarding the economic burden of respiratory syncytial virus (RSV) disease in low-resource settings. This study aimed to estimate the cost per episode of hospital admissions due to RSV severe disease in Argentina. METHODS: This is a prospective cohort study that collected information regarding 256 infants under 12 months of age with acute lower respiratory tract infection (ALRTI) due to RSV in two public hospitals of Buenos Aires between 2014 and 2016. Information on healthcare resource use was collected from the patient's report and its associated costs were estimated based on the financial database and account records of the hospitals. We estimated the total cost per hospitalization due to RSV using the health system perspective. The costs were estimated in US dollars as of December 2022 (1 US dollar = 170 Argentine pesos). RESULTS: The mean costs per RSV hospitalization in infants was US$587.79 (95% confidence interval [CI] $535.24 - $640.33). The mean costs associated with pediatric intensive care unit (PICU) admission more than doubled from those at regular pediatric wards ($1,556.81 [95% CI $512.21 - $2,601.40] versus $556.53 [95% CI $514.59 - $598.48]). CONCLUSIONS: This study shows the direct economic impact of acute severe RSV infection on the public health system in Argentina. The estimates obtained from this study could be used to inform cost-effectiveness analyses of new preventive RSV interventions being developed.

Infecciones por Virus Sincitial Respiratorio , Virus Sincitial Respiratorio Humano , Infecciones del Sistema Respiratorio , Lactante , Humanos , Niño , Estudios Prospectivos , Argentina/epidemiología , Infecciones por Virus Sincitial Respiratorio/epidemiología , Hospitalización , Infecciones del Sistema Respiratorio/epidemiología , Costo de Enfermedad
BMC Psychiatry ; 24(1): 113, 2024 Feb 09.
Artículo en Inglés | MEDLINE | ID: mdl-38336694


BACKGROUND: Psychotic symptoms may be less common than anxiety or affective symptoms, but they are still frequent and typically highly debilitating. Community members can have a role in helping to identify, offer initial help and facilitate access to mental health services of individuals experiencing psychosis. Mental health first aid guidelines for helping a person experiencing psychosis have been developed for the global north. This study aimed to adapt the English- language guidelines for Chile and Argentina. METHODS: A Delphi expert consensus study was conducted with two panels of experts, one of people with lived experience of psychosis (either their own or as a carer; n = 29) and another one of health professionals (n = 29). Overall, 249 survey items from the original English guidelines and 26 items suggested by the local team formed a total of 275 that were evaluated in the first round. Participants were invited to rate how essential or important those statements were for Chile and Argentina, and encouraged to suggest new statements if necessary. These were presented in a second round. Items with 80% of endorsement by both panels were included in the guidelines for Chile and Argentina. RESULTS: Data were obtained over two survey rounds. Consensus was achieved on 244 statements, including 26 statements locally generated for the second round. Almost 20% of the English statements were not endorsed (n = 50), showing the applicability of the original guidelines but also the importance of culturally adapting them. Attributions and tasks expected to be delivered by first aiders were shrunk in favour of a greater involvement of mental health professionals. Self-help strategies were mostly not endorsed and as were items relating to respecting the person's autonomy. CONCLUSIONS: While panellists agreed that first aiders should be aware of human rights principles, items based on recovery principles were only partially endorsed. Further research on the dissemination of these guidelines and development of a Mental Health First Aid training course for Chile and Argentina is still required.

Salud Mental , Trastornos Psicóticos , Humanos , Primeros Auxilios , Chile , Argentina , Técnica Delfos , Trastornos Psicóticos/terapia , Encuestas y Cuestionarios
An Acad Bras Cienc ; 96(1): e20191190, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38359284


Explanations for differences in thermal biology within and between species of lizards employ concepts of phylogenetic inertia and plasticity. We compared the thermal biology of three liolaemid species in the Andean highlands in Argentina: two allopatric congeners (Phymaturus williamsi and P. aguanegra) each in syntopy with Liolaemus parvus. We predicted intra and inter-generic differences in ecophysiological traits and periods of activity at both sites, ecotypic differences between the (labile) Liolaemus populations, but predicted no interspecific differences between the (putatively conservative) Phymaturus. We determined the operative temperatures (T e), field body temperatures (T b), preferred temperatures (T pref), effectiveness of thermoregulation (E), and activity periods. As expected, P. williamsi differed from L. parvus in T b, T pref, and activity periods, likely as result of niche segregation. Contrary to predictions, the Phymaturus populations exhibited differentiation in T b and T pref, while L. parvus populations differed in T pref and E. Accordingly, Phymaturus species tend to be effective thermoregulators whereas L. parvus populations behave as good thermoregulators or thermoconformers depending on thermal conditions in fluctuating habitats. Phymaturus may be less evolutionarily conservative than previously suggested. The suite of co-evolving traits affecting thermal ecology may not be collectively conservative nor labile but rather a continuum between both evolutionary paths.

Lagartos , Animales , Argentina , Filogenia , Temperatura Corporal , Temperatura
Int J Gynaecol Obstet ; 164 Suppl 1: 21-30, 2024 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-38360031


Abortion laws are key in creating an enabling environment that facilitates the advancement of people's sexual and reproductive health and rights. Around 50 countries have liberalized their abortion laws in the last decades by adding new grounds allowing abortion. The road toward the expansion of legal abortion is a long, highly sensitive, and difficult process. The specific role of healthcare providers in influencing abortion law reforms has been scarcely studied. With the objective to better understand their (potential) roles, a qualitative study was conducted in 2021 focusing on three countries that had recently liberalized their abortion regulations: Argentina, South Korea, and Ireland. For each country, key informant interviews were conducted with actors in advocacy for legal change, the majority with healthcare providers. The study results indicate that healthcare providers can contribute to the expansion of legal abortion through their influence on public and legal debates. Healthcare providers were found to be scientifically credible and trustworthy. Their voice and argumentation counteracted anti-rights arguments and addressed information gaps, by providing specific clinical experiences and medical information. Healthcare providers amplified women's experiences through their testimonies and had entry points within governmental bodies, which facilitated their advocacy. These healthcare providers often functioned as individual operating obstetrician/gynecologists or general practitioners who were engaged in networks of health professionals or had previous advocacy experience. In a global context of social and political contention around abortion, extending the engagement of healthcare providers in law and policy deliberation on abortion appears to be useful. This requires recognizing the diversity of roles that healthcare providers can take up, creating a safe environment in which they can operate, equipping them with skills that go beyond the medical expert role and facilitating strategic partnerships that seek complementarity between multiple stakeholders, building on the uniqueness of each stakeholder's expertise.

Aborto Inducido , Aborto Legal , Embarazo , Femenino , Humanos , Argentina , Irlanda , Personal de Salud , República de Corea
PeerJ ; 12: e16861, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38361769


Background: Knowledge of the physical and environmental conditions that may limit the migration of invasive species is crucial to assess the potential for expansion outside their native ranges. The cactus moth, Cactoblastis cactorum, is native to South America (Argentina, Paraguay, Uruguay and Brazil) and has been introduced and invaded the Caribbean and southern United States, among other regions. In North America there is an ongoing process of range expansion threatening cacti biodiversity of the genus Opuntia and the commercial profits of domesticated Opuntia ficus-indica. Methods: To further understand what influences the distribution and genetic structure of this otherwise important threat to native and managed ecosystems, in the present study we combined ecological niche modeling and population genetic analyses to identify potential environmental barriers in the native region of Argentina. Samples were collected on the host with the wider distribution range, O. ficus-indica. Results: Significant genetic structure was detected using 10 nuclear microsatellites and 24 sampling sites. At least six genetic groups delimited by mountain ranges, salt flats and wetlands were mainly located to the west of the Dry Chaco ecoregion. Niche modeling supports that this region has high environmental suitability where the upper soil temperature and humidity, soil carbon content and precipitation were the main environmental factors that explain the presence of the moth. Environmental filters such as the upper soil layer may be critical for pupal survival and consequently for the establishment of populations in new habitats, whereas the presence of available hosts is a necessary conditions for insect survival, upper soil and climatic characteristics will determine the opportunities for a successful establishment.

Mariposas Nocturnas , Opuntia , Animales , Estados Unidos , Mariposas Nocturnas/genética , Argentina , Ecosistema , Brasil
Parasitol Res ; 123(2): 136, 2024 Feb 16.
Artículo en Inglés | MEDLINE | ID: mdl-38363370


Morphological abnormalities in fleas seem to be common in nature and are under reported in Argentina. In this note, we describe anomalies in two males and one female of Alectopsylla unisetosa Mahnert (Ischnopsyllidae) and one of Polygenis sp. (Rhopalopsyllidae) male collected from small mammals in the provinces of Neuquen and Salta, Argentina. In all specimens, the anomalies were observed at the level of the genitalia recognized as partial castration. The structures mainly affected were the modified abdominal segments, the aedeagus (in male), and the spermatheca (in female). The present communication is the first one devoted exclusively to teratogenous fleas in Argentina.

Quirópteros , Infestaciones por Pulgas , Siphonaptera , Masculino , Femenino , Animales , Siphonaptera/anatomía & histología , Roedores , Argentina , Infestaciones por Pulgas/veterinaria , Castración
Parasitol Res ; 123(2): 129, 2024 Feb 09.
Artículo en Inglés | MEDLINE | ID: mdl-38332310


This study aimed to determine the nPCR-RFLP genotypes of newly obtained T. gondii isolates from human congenital toxoplasmosis cases in Argentina and to determine their allelic profiles for virulence genes ROP18/ROP5. In addition, the ROP18/ROP5 profiles were also determined for previously characterized T. gondii samples. Isolation from congenital toxoplasmosis cases was carried out in mouse bioassay from two placentas (P1 and P2). Genotyping for the new human isolates was performed by nPCR-RFLP using 10 markers. The samples analyzed for ROP18/ROP5 included the two newly obtained isolates (from the congenital toxoplasmosis cases) and nine previously genotyped T. gondii DNA samples from humans and chickens. The results for P1 and P2 named as TgHm18-02Arg and TgHm19-01Arg showed ToxoDB genotypes #14 (non-archetypal) and #2 (clonal type III), respectively. Non-archetypal #14 has been isolated from human cases before in Argentina. However, this is the first report of T. gondii clonal type III in a human case in the country. The ROP18/ROP5 combination was detected in nine samples: 3/3 (n = 1), 4/3 (n = 4), 4/4 (n = 3), and 3-4/4 (n = 1). Notably, the 4/4 profile was identified for the first time and exclusively in T. gondii samples from Misiones province (which borders southern Brazil). Further studies are required to corroborate the regionalization of the ROP18/ROP5 profiles in Argentina.

Toxoplasma , Toxoplasmosis Animal , Toxoplasmosis Congénita , Ratones , Embarazo , Femenino , Humanos , Animales , Argentina/epidemiología , Pollos , Genotipo
Gastroenterol. hepatol. (Ed. impr.) ; 47(2): 140-148, feb. 2024. tab, graf
Artículo en Inglés | IBECS | ID: ibc-ADZ-140


Background The COVID-19 pandemic created a backlog in colorectal cancer (CRC) screening and surveillance colonoscopies. The real impact in Argentina is not fully known. Goal To estimate the impact of the COVID-19 pandemic on CRC prevention by comparing the number of CRC screening and surveillance consults in a clinical decision support-tool used in Argentina before, during and after pandemic lockdown. Methods We analyzed data from May 2019 to December 2021 from CaPtyVa, a clinical decision support tool for CRC screening and surveillance. Queries were divided in pre-pandemic (May 2019 to March 2020), lockdown (April 2020 to December 2020), and post-lockdown (January 2021 to December 2021). The number of CRC monthly screening and surveillance visits were compared among the three periods and stratified according to CRC risk. Results Overall, 27,563 consults were analyzed of which 9035 were screening and 18,528 were surveillance. Pre-pandemic, the median number of screening consults was 346 per month (IQR25–75 280–410). There was a decrease to 156 (80–210)/month (p < 0.005) during lockdown that partially recovered during post-lockdown to 230 (170–290)/month (p = 0.05). Pre-pandemic, the median number of surveillance consults was 716 (560–880)/month. They decreased to 354 (190–470)/month during lockdown (p < .05) and unlike screening, completely recovered during post-lockdown to 581 (450–790)/month. Conclusions There was a >50% decrease in the number of CRC screening and surveillance consults registered in CaPtyVa during lockdown in Argentina. Post-lockdown, surveillance consults recovered to pre-pandemic levels, but screening consults remained at 66% of pre-pandemic levels. This has implications for delays in CRC diagnoses and patient outcomes (AU)

Antecedentes La pandemia de COVID-19 provocó atraso en las colonoscopias de detección y vigilancia del cáncer colorrectal (CCR). Objetivo Estimar el impacto de la pandemia de COVID-19 en la prevención del CCR comparando el número de consultas de pesquisa y vigilancia del CCR en una herramienta digital de apoyo a la decisión clínica utilizada en Argentina antes, durante y después del confinamiento. Métodos Analizamos datos entre mayo 2019 a diciembre 2021 de CaPtyVa, una herramienta digital de apoyo a la toma de decisiones clínicas para la pesquisa y vigilancia del CCR. Las consultas se dividieron en prepandemia (mayo 2019- marzo 2020), confinamiento (abril 2020- diciembre 2020) y post-confinamiento (enero 2021-diciembre 2021). El número de visitas mensuales de pesquisa y vigilancia de CCR se comparó entre períodos y se estratificó según riesgo de CCR. Resultados Prepandemia, la mediana de consultas de detección fue 346 mes (IQR25-75 280-410). Hubo una disminución a 156 (80-210)/mes (p<0,005) durante el confinamiento que ascendió a 230 (170-290)/mes (p=0,05) en el post-confinamiento. Prepandemia, la mediana de consultas de vigilancia fue 716 (560-880)/mes. Disminuyeron a 354 (190-470)/mes durante el confinamiento (p<0,05) y se recuperaron por completo durante el post-confinamiento. Conclusiones Hubo una disminución >50% en el número de consultas de detección y vigilancia de CCR registradas en CaPtyVa durante el confinamiento en Argentina. Post-confinamiento, las consultas de vigilancia se recuperaron a niveles prepandemia, pero las consultas de detección se mantuvieron en el 66 % de niveles históricos. Esto tendría implicaciones en los diagnósticos y pronósticos de CCR (AU)

Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , /epidemiología , Neoplasias Colorrectales/diagnóstico , Neoplasias Colorrectales/epidemiología , Sistemas de Apoyo a Decisiones Clínicas , Neoplasias , Argentina/epidemiología , Control de Enfermedades Transmisibles , Detección Precoz del Cáncer , Pandemias/prevención & control , Estudios Retrospectivos
PLoS One ; 19(1): e0295798, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38175833


OBJECTIVE: This study aimed to estimate the budget impact of the incorporation of venetoclax for the treatment of patients with Acute Myeloid Leukemia (AML) over 75 years of age or those with comorbidities and contraindications for the use of intensive chemotherapy, from the perspective of the social security and the private third-party payers in Argentina. METHODS: A budget impact model was adapted to estimate the cost difference between the current scenario (azacitidine, decitabine and low doses of cytarabine) and the new scenario (incorporation of venetoclax) for a third-party payer over a time horizon of three years. Input parameters were obtained from a literature review, validated or complemented by expert opinion using a modified Panel Delphi approach. All direct medical costs were estimated by the micro-costing approach and were expressed in US dollars (USD) as of September 2020 (1 USD = 76.18 Argentine pesos). RESULTS: For a third-party payer with a cohort of 1,000,000 individuals covered, incorporating venetoclax was associated with an average budget impact per-member per-month (PMPM) of $0.11 USD for the social security sector and $0.07 USD for the private sector. The duration of treatment with venetoclax was the most influential parameter in the budget impact results. CONCLUSION: The introduction of venetoclax was associated with a positive and slight budget impact. These findings are informative to support policy decisions aimed to expand the current treatment landscape of AML.

Antineoplásicos , Leucemia Mieloide Aguda , Humanos , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Argentina , Compuestos Bicíclicos Heterocíclicos con Puentes/uso terapéutico , Leucemia Mieloide Aguda/tratamiento farmacológico , Sector Privado , Antineoplásicos/economía , Antineoplásicos/uso terapéutico
An Acad Bras Cienc ; 95(suppl 2): e20220956, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38198397


Malaria is the most important parasitic disease worldwide. In 2019, more than 679,441 cases of malaria were reported in the American region. During this study, Argentina was in malaria pre-elimination autochthonous transmission phase with the aim of being declared as malaria-free country. The aim of this work was to assess the influence of remote sensing spectral indices (NDVI, NDWI) and climatic variables (temperature, relative humidity and precipitation) on the distribution and abundance of Anopheles mosquitoes, in four localities with different degrees of anthropogenic disturbance and with previous malaria cases records located , in a historical malarious area in northeastern of Argentina. Between June 2012 and July 2014, mosquitoes were collected. We collected 535 Anopheles adult mosquitoes. Anopheles strodei s.l. was the most abundant species. The greatest richness, diversity and abundance of species were registered in wild and semi-urban environments. The abundance of Anopheles presented a negative association with relative humidity and mean temperature, but positive with mean maximum temperature. The most important variables determining Anopheles total abundance and distribution were NDWI Index and distance to vegetation. The abundance of An. strodei s.l., was positive associated with water areas whereas the NDVI Index was negatively associated.

Anopheles , Malaria , Animales , Argentina , Temperatura , Agua
Vet Parasitol Reg Stud Reports ; 47: 100954, 2024 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-38199678


This study describes a case of Calodium hepaticum (Trichinellida: Capillariidae) infection in an adult rat (Rattus rattus) from the periurban area of the city of La Plata in the province of Buenos Aires, Argentina. The rat was found with neurological signs (ataxia, lethargy, and episodes of unresponsiveness) in the food storage of a goat production facility. The liver was observed with hepatomegaly and diffuse and irregular yellowish-white spots appearing in striae or small nodules on the external surface and inside the liver. Subsequent microscopic and histopathological studies were performed. Eggs were observed by direct microscopy of the impression smear of liver tissue. A multifocal granulomatous tissue reaction with different stages of fibrocellular tissue was observed in the liver parenchyma. The granulomas contained adults and degenerated eggs delimited by an intense infiltrate of mononuclear cells. Macro and microscopic observations and histopathological liver lesions were compatible with C. hepaticum infection. To our knowledge, this is the first confirmation of C. hepaticum infection in R. rattus in Argentina, increasing the host record of this parasite and a new record of distribution in goat production systems in the country.

Capillaria , Hígado , Animales , Ratas , Argentina/epidemiología , Cabras , Microscopía/veterinaria
J Helminthol ; 98: e11, 2024 Jan 24.
Artículo en Inglés | MEDLINE | ID: mdl-38263742


Acanthocephalans constitute a small taxonomic group related to rotifers and specialized in a parasitic lifestyle. Anurans act as paratenic and definitive hosts and infections always occur trophically. Our objective is to describe and summarize the richness of acanthocephalans in Neotropical anurans. We conducted a literature review in the main research databases, compiling data published until August 2021. We identified 66 articles with records of acanthocephalan-anuran association, 53.03% were carried out in Brazil. We detected 108 species of anurans from 11 families parasitized by acanthocephalans. With the exception of Bufonidae, Hylidae and Leptodactylidae, which are relatively well-studied families, interaction with acanthocephalans remains largely unexplored for most anuran species. We found six families of acanthocephalans: Centrorhynchidae, Echinorhynchidae, Oligacanthorhynchidae, Cavisomidae, Neoechinorhynchidae and Plagiorhynchidae. Centrorhynchidae and Echinorhynchidae presented the largest number of taxa associated with anurans. The largest number of records corresponded to acanthocephalans in the larval stage (cystacanths), for which anurans act as paratenic hosts. We observed a lack of specific taxonomic resolution in the identifications of most reports, because a large part of the records in the larval stage make morphological identification difficult. Brazil, Mexico, Paraguay, Argentina, Ecuador and Peru are the countries with the most records, while Costa Rica, Venezuela, Colombia, Chile and Uruguay exhibited the lowest publication numbers, resulting in gaps in the distribution of acanthocephalans. We expanded the known number of anuran species parasitized by acanthocephalans, compared to the last published review. Overall, we aim to contribute to the understanding of diversity within this intriguing but understudied group.

Acantocéfalos , Parásitos , Animales , Anuros , Bufonidae , Argentina , Larva
Exp Appl Acarol ; 92(1): 151-159, 2024 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-38219227


This study presents the results of the molecular detection of tick-borne microorganisms in Amblyomma tigrinum Koch collected near the city of Viedma, Río Negro, Argentina. Ticks were collected in their non-parasitic stage, on pet dogs and on Lycalopex gymnocercus (Pampa fox). Also, six tick samples from humans were analyzed. All ticks were morphologically identified to species level and genomic DNA was extracted. The DNA samples were examined by end point PCR assays to amplified DNA of Anaplasma sp., Babesia sp., Ehrlichia sp., Rickettsia sp. and Theileria sp. Although all tested DNA samples from the collected ticks resulted negative to the detection of Piroplasmida and Rickettsia spp., 16 samples (16.5%, including all hosts) were positive in the 16S rDNA gene PCR that detects bacteria from the Anaplasmataceae family. Phylogenetic analysis of seven obtained partial sequences resulted in the identification of three bacteria: two Ehrlichia spp. (related to Ehrlichia sp. strain Iberá and strain Viedma) and Candidatus Anaplasma boleense. The latter finding represents the first detection of this novel Candidatus species in A. tigrinum. Based on the results of this study, it must be assumed that the diversity of bacteria of the Anaplasmataceae family in Argentina is greater than previously thought, and that these bacteria can infect a wide range of domestic and wild animals.

Anaplasmataceae , Enfermedades de los Perros , Ixodidae , Rickettsia , Enfermedades por Picaduras de Garrapatas , Garrapatas , Humanos , Animales , Perros , Garrapatas/microbiología , Ixodidae/microbiología , Amblyomma/genética , Argentina , Filogenia , Ehrlichia , Rickettsia/genética , Anaplasma/genética , ADN Bacteriano/análisis , Enfermedades por Picaduras de Garrapatas/veterinaria , Enfermedades de los Perros/parasitología
PLoS One ; 19(1): e0297053, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38241305


Sympatric, phylogenetically related and morphologically similar species that overlap in their distributions at a regional scale display different patterns of co-occurrence at local assemblages. Occurrence of each species at local scales might be the result of interspecific competition for limiting resources. However, these patterns could also arise from species-specific habitat preferences along the abiotic or land use gradients. To assess the role of these mechanisms, we investigated niche partitioning among sympatric tinamou species occurring in semiarid woodlands of central Argentina. We used occupancy models incorporating habitat characteristics and interspecific interactions, while accounting for detectability, to examine the spatial overlap among elegant crested tinamous (Eudromia elegans), brushland tinamous (Nothoprocta cinerascens), and nothura tinamous (Nothura darwinii and N. maculosa) across a wide regional scale. In addition, we investigated time partitioning among these species by estimating the degree of overlap in their daily activity patterns. The regional distribution of the three species was influenced by the gradient in plant productivity and vegetation structure, in agreement with their broad habitat requirements. We also found that the occurrence of each species was presumably affected by the presence of one or two predator species. Models including interactions among tinamou species found weak negative and positive interactions among species pairs, suggesting that co-occurrence patterns were mainly driven by species-specific habitat use rather than interspecific competition. The three species were diurnal, showing two main peaks of activity, and overlapped widely in their overall diel activity, although subordinate species tended to shift their activity patterns to reduce encounters with the dominant tinamou species, suggesting some segregation in this niche dimension. Projected changes in rainfall seasonality and warmer conditions in this region could benefit elegant crested tinamous over the other two species, although climate and land use changes will likely have a negative impact on all tinamou species.

Ecosistema , Bosques , Argentina , Simpatría , Clima
Medicina (B Aires) ; 84(1): 96-101, 2024.
Artículo en Español | MEDLINE | ID: mdl-38271936


INTRODUCTION: The aim of the study was to investigate the relationship between the number of positive cases of COVID-19 and the environmental parameters of temperature and humidity in five departments of the province of Catamarca, Argentina. METHODS: The departments Capital, Andalgalá, Paclín, Ambato and Tinogasta, Catamarca, Argentina, were studied. Between April 2021 and April 2022 variables analyzed were: number of COVID-19 cases, temperature, and percentage of environmental humidity. The correlation of variables was analyzed by the coefficient of Spearman. RESULTS: The temperature with the numbers of COVID-19 cases show inverse correlation values that ranged between -0.56 and -0.34. The humidity percentages show a slightly positive relationship only for Capital and Andalgalá, with values of 0.34 and 0.40 with the number of cases. CONCLUSION: The results showed a relationship between the number of positive cases of COVID-19 and the environmental parameters of temperature and humidity in five departments in the province of Catamarca.

Introducción: El objetivo del trabajo fue estudiar la relación entre el número de casos positivos de COVID-19 y los parámetros ambientales de temperatura y humedad en cinco departamentos de la provincia de Catamarca. Métodos: Los departamentos estudiados fueron Capital, Andalgalá, Paclín, Ambato y Tinogasta, Catamarca, Argentina. Las variables número de casos COVID-19, temperatura y porcentaje de humedad ambiental fueron obtenidos entre abril de 2021 y abril de 2022. La correlación de variables se analizó mediante el coeficiente de Spearman. Resultados: La temperatura, en relación con los nú- meros de casos por COVID-19 mostró valores de correlación inversa que oscilaron entre -0.56 y -0.34. El porcentaje de humedad, indicó una relación levemente positiva con el número de casos solo para Capital y Andalgalá con valores de 0.34 y 0.40. Conclusión: Los resultados muestran una relación entre el número de casos positivos de COVID-19 y los parámetros ambientales de temperatura y humedad en cinco departamentos de la provincia de Catamarca.

COVID-19 , Humanos , COVID-19/epidemiología , Argentina/epidemiología
Medicina (B Aires) ; 84(1): 81-86, 2024.
Artículo en Español | MEDLINE | ID: mdl-38271934


INTRODUCTION: Dengue is a disease transmitted by mosquitoes of the Aedes genus; this has presented a historical increase in cases in South America, which represents a public health problem. From the Febrile Emergency Unit (UFU) of Hospital Muñiz, the laboratory results were analyzed and the circulating serotype was identified at the level of the Autonomous City of Buenos Aires (CABA), confirming the proportion of indigenous cases, recording symptoms and epidemiology. The objective of this analysis is to highlight the increase in indigenous cases of dengue in CABA. METHODS: An observational and retrospective study was carried out, from January 1 to May 8, 2023, of the positive PCR results for dengue. RESULTS: 1159 patients with febrile symptoms were assisted, of which 554 (47.7%) were probable cases while the remaining 542 (46.7%) were febrile syndromes of another etiology. Of the probable cases, 162 with positive PCR results (29%) were evaluated, of which 18 (11%) were imported and 144 (89%) native. DENV-2 predominated (86% of confirmed cases). The clinical manifestations were fever (100%), myalgia (100%), headache (98%), arthralgia (87%), nausea (46%), and retroocular pain (39%). DISCUSSION: For 10 years, there has been an increase in the number of indigenous dengue cases in CABA. In the analysis of this article, autochthonous dengue appears as an outbreak at the city level. Notification of the clinic and epidemiology is important to consider public health strategies in the fight against dengue and possible new studies related to outbreaks and epidemics.

Introducción: El dengue es una enfermedad transmitida por mosquitos del género Aedes, que presenta un aumento histórico de casos en América del Sur, y representa un problema en salud pública. Desde la Unidad Febril de Urgencias (UFU) del Hospital Muñiz se analizaron los resultados de laboratorio y se identificó el serotipo circulante en la Ciudad Autónoma de Buenos Aires (CABA), la proporción de casos autóctonos, registrando sintomatología y epidemiología. El objetivo de este análisis fue determinar el incremento de casos autóctonos de dengue en CABA. Métodos: Estudio observacional y retrospectivo, entre 1 de enero y 8 de mayo de 2023, de los casos con PCR positiva para dengue. Resultados: Se atendieron 1159 pacientes con sintomatología febril, de los cuales 554 (47.7%) fueron casos probables, mientras que los restantes 542 (46.7%) fueron síndromes febriles de otra etiología. De los casos probables se evaluaron 162 con PCR positiva (29%), de los que 18 (11%) fueron importados y 144 (89%) autóctonos. Predominó el DENV-2 (86% de los casos confirmados). Las manifestaciones clínicas fueron: fiebre (100%), mialgias (100%), cefalea (98%), artralgias (87%), náuseas (46%), dolor retroocular (39%). Discusión: En los últimos 10 años se registró un aumento en el número de casos de dengue autóctono en CABA. Al análisis de este artículo el dengue autóctono se presenta como un brote a nivel de la ciudad. Es importante la notificación de la clínica y epidemiología para considerar estrategias en salud pública en la lucha contra el dengue y posibles nuevos estudios relacionados con brotes y epidemias.

Enfermedades Transmisibles , Dengue , Animales , Humanos , Dengue/diagnóstico , Dengue/epidemiología , Argentina/epidemiología , Estudios Retrospectivos , Enfermedades Transmisibles/epidemiología , Brotes de Enfermedades
Medicina (B Aires) ; 84(1): 143-147, 2024.
Artículo en Español | MEDLINE | ID: mdl-38271941


Monkeypox is a zoonotic viral disease caused by a virus of the genus Orthopoxvirus. As of January 1, 2022, it has been reported in 110 WHO Member States. It presents with fever, fatigue, painful lymphadenopathy, and rash. It lasts between 2 and 4 weeks. It is usually self-limited, but severe cases have been described in immunocompromised people. This study describes cases of monkeypox in women, diagnosed between June 2022 and February 2023, and it reports epidemiology, clinical aspects, and complications after infection. A retrospective observational study was carried out in the Febrile Emergency Unit (UFU), reviewing positive cases (RT-PCR) for monkeypox and the population with female biological sex was selected. They were questioned about gynecological complications, menstrual pattern, dyspareunia and pelvic pain. 340 consultations for monkeypox were made, 214 (63%) were positive, 211 cases (99%) male and 3 cases (1%) female. Among these cases is a trans woman, who was not included. The average age is 31 years, immunocompetent, with a negative serology report for HIV, syphilis, hepatitis B and C. Both cases had sexual intercourse without a barrier method. The most frequent symptoms are asthenia and skin lesions, especially in the upper and lower limbs, perianal and genital region. As a risk factor they presented unprotected sexual contact. Within the differential diagnoses, other sexually transmitted infections (STIs) should be considered. There were no gynecological complications reported during follow-up.

La viruela símica es una enfermedad viral zoonótica debida a un virus del género Orthopoxvirus. Desde el 1 de enero de 2022, se ha notificado en 110 Estados Miembros de la OMS. Se presenta con fiebre, astenia, linfoadenopatías dolorosas y exantema. Dura entre 2 y 4 semanas. Suele ser autolimitada y se han descrito casos graves en personas inmunocomprometidas. El presente trabajo describe casos de viruela símica en mujeres, diagnosticados entre junio del 2022 y febrero del 2023 Se realizó un estudio observacional retrospectivo en la Unidad Febril de Urgencias (UFU), revisando casos positivos (RT-PCR) para viruela símica y se seleccionó la población con sexo biológico femenino. Se consultó sobre complicaciones ginecológicas, patrón menstrual, dispareunia y dolor pélvico. Se realizaron 340 consultas por viruela símica, 214 (63%) fueron positivos, 211 casos (99%) de sexo masculino y 3 casos (1%) femeninos. Dentro de estos casos se encuentra una mujer trans, la cual no se incluyó. La edad promedio es de 31 años, inmunocompetentes, con reporte de serologías negativas para HIV, sífilis, hepatitis B y C. Ambos casos mantuvieron relaciones sexuales sin método de barrera. Los síntomas más frecuentes fueron astenia y lesiones en piel, sobre todo en miembros superiores e inferiores, región perianal y genital. Como factor de riesgo presentaron contacto sexual sin protección. Dentro de los diagnósticos diferenciales, debe tenerse en cuenta otras infecciones de transmisión sexual (ITS). En seguimiento epidemiológico no refirieron complicaciones ginecológicas.

Enfermedades de Transmisión Sexual , Sífilis , Humanos , Masculino , Femenino , Adulto , /epidemiología , Argentina/epidemiología , Enfermedades de Transmisión Sexual/epidemiología , Factores de Riesgo
Medicina (B Aires) ; 84(1): 29-46, 2024.
Artículo en Español | MEDLINE | ID: mdl-38271930


INTRODUCTION: The objective of this study was to analyze the geographic variability and the relationship between social determinants of health and COVID-19 lethality in Bariloche. METHODS: A database from the National Epidemiological Surveillance System was used to analyze COVID-19 positive cases from January 2020 to December 2021. The data were geocoded and incorporated into a geographic information system (GIS). A three-step analytical framework was applied to measure health inequity, using socioeconomic indicators and access to services. A multivariate analysis was conducted to predict fatality. RESULTS: A total of 25 020 COVID-19 cases were diagnosed in Bariloche during the study period. The fatality rate was 2.1%. Significant variability in socioeconomic indicators was observed among different territorial delegations of the city. DISCUSSION: The results showed health inequities and an association between social determinants and COVID-19 lethality in Bariloche. Individuals living in areas with higher socioeconomic vulnerability had a higher risk of mortality. These findings highlight the importance of addressing health inequities in a pandemic response.

Introducción: El objetivo de este estudio fue examinar cómo la variabilidad geográfica y los determinantes sociales de la salud influyen en la tasa de letalidad por COVID-19 en Bariloche. Métodos: Se utilizó una base de datos del Sistema Nacional de Vigilancia Epidemiológica para analizar los casos positivos de COVID-19 desde enero de 2020 hasta diciembre de 2021. Los datos se geo-codificaron y se incorporaron en un sistema de información geográfica (SIG). Se aplicó un marco de análisis en tres pasos para medir la inequidad en salud, utilizando indicadores socioeconómicos y de acceso a servicios. Se realizó un análisis multivariado para predecir la letalidad. Resultados: Se diagnosticaron un total de 25 020 casos de COVID-19 en Bariloche durante el período de estudio. La letalidad fue del 2.1%. Se observó una variabilidad significativa en indicadores socioeconómicos entre las diferentes delegaciones territoriales de la ciudad. Discusión: Los resultados mostraron inequidades en salud y una asociación entre determinantes sociales y letalidad por COVID-19 en Bariloche. Las personas que vivían en áreas con mayor vulnerabilidad socioeconómica presentaron un mayor riesgo de mortalidad. Estos hallazgos resaltan la importancia de abordar las inequidades en salud en la respuesta a una pandemia.

COVID-19 , Inequidades en Salud , Humanos , COVID-19/mortalidad , Análisis Multivariante , Factores Socioeconómicos , Argentina/epidemiología
BMC Pregnancy Childbirth ; 24(1): 67, 2024 Jan 17.
Artículo en Inglés | MEDLINE | ID: mdl-38233792


BACKGROUND: Improving the understanding of non-clinical factors that lead to the increasing caesarean section (CS) rates in many low- and middle-income countries is currently necessary to meet the challenge of implementing effective interventions in hospitals to reverse the trend. The objective of this study was to study the influence of organizational factors on the CS use in Argentina, Vietnam, Thailand and Burkina Faso. METHODS: A cross-sectional hospital-based postpartum survey was conducted in 32 hospitals (8 per country). We selected women with no potential medical need for CS among a random sample of women who delivered at each of the participating facilities during the data collection period. We used multilevel multivariable logistic regression to analyse the association between CS use and organizational factors, adjusted on women's characteristics. RESULTS: A total of 2,092 low-risk women who had given birth in the participating hospitals were included. The overall CS rate was 24.1%, including 4.9% of pre-labour CS and 19.3% of intra-partum CS. Pre-labour CS was significantly associated with a 24-hour anaesthetist dedicated to the delivery ward (ORa = 3.70 [1.41; 9.72]) and with the possibility to have an individual room during labour and delivery (ORa = 0.28 [0.09; 0.87]). Intra-partum CS was significantly associated with a higher bed occupancy level (ORa = 1.45 [1.09; 1.93]): intrapartum CS rate would increase of 6.3% points if the average number of births per delivery bed per day increased by 10%. CONCLUSION: Our results suggest that organisational norms and convenience associated with inadequate use of favourable resources, as well as the lack of privacy favouring women's preference for CS, and the excessive workload of healthcare providers drive the CS overuse in these hospitals. It is also crucial to enhance human and physical resources in delivery rooms and the organisation of intrapartum care to improve the birth experience and the working environment for those providing care. TRIAL REGISTRATION: The QUALI-DEC trial is registered on the Current Controlled Trials website ( ) under the number ISRCTN67214403.

Cesárea , Países en Desarrollo , Embarazo , Femenino , Humanos , Estudios Transversales , Argentina , Burkina Faso , Tailandia , Vietnam , Hospitales