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1.
Georgian Med News ; (298): 13-16, 2020 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-32141840

RESUMEN

Acute thrombophlebitis of the superficial veins is an urgent problem as it can spread to the deep veins with the subsequent development of pulmonary embolism. The social implications of varicotrombophlebitis are the long-term disability of most patients up to complete disability, so finding the least invasive methods of correction of the discussed disease is a pressing issue of modern phlebology. The research objective is to carry out a comparative analysis of the quality of life of patients with acute ascending thrombophlebitis of the great sapheneous vein after treatment with high-frequency endovenous welding and standard phlebectomy. The results of treatment of 63 patients with acute ascending thrombophlebitis of great saphenous vein (GSV) with III and IV class of thrombophlebitis, who were hospitalized in the surgical wards of the Municipal Clinical Hospital No. 8 of Kyiv from 2017 to 2018, were analyzed. Welding of the thrombotic vein segment was performed using an endovenous welding catheter (WC). Quality of life (QOL) results were assessed using CIVIQ2 (Chronic Venous Insufficiency Questionnaire). According to ultrasound duplex scanning, complete vein ablation occurred in 97.22% of patients after endovenous welding (EW) of thrombotic GSV. In all patients of Group I already on day 2, the total rate of QOL by all factors (pain, physical, social, psychological) significantly (p<0.05) exceeded the presurgery values and was 79.3%, when before treatment this indicator was 4.3% higher. At follow-up, QOL values continued to improve over all observation periods compared to the previous term (p <0.05). Quality of life restriction in connection with pain, social and psychological factors after EW decreased 2.1 times(p<0.05), when in control group patients - only 1.2 times. The revealed advantages of the method of high-frequency endovenous welding by all indicators of quality of life over standard phlebectomy allow recommending this method for wide practical application.


Asunto(s)
Ablación por Catéter , Terapia por Láser , Calidad de Vida/psicología , Vena Safena/cirugía , Tromboflebitis/cirugía , Insuficiencia Venosa/cirugía , Soldadura , Humanos , Tromboflebitis/psicología , Resultado del Tratamiento , Insuficiencia Venosa/complicaciones , Insuficiencia Venosa/diagnóstico
2.
Braz Oral Res ; 34: e009, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32049110

RESUMEN

The sense of coherence (SOC) is a measure of global orientation regarding the ability of individuals to cope with stressful situations. The aim of the present study was to evaluate the association between SOC and quality of life (QoL) and clinical and sociodemographic characteristics among survivors of oral, oropharynx, hypopharynx, or larynx cancer. A cross-sectional study was conducted with 90 cancer patients in follow up at the Santa Maria University Hospital in southern Brazil who had completed conformal 3D radiotherapy at least three months earlier. QoL was assessed using the University of Washington Quality of Life (UW-QOL) questionnaire and SOC was measured using the Brazilian version of the SOC-13 questionnaire. Data on socio-demographic characteristics and the disease were obtained from patients' charts. Oral clinical conditions were also evaluated. Associations between exploratory variables and mean UW-QOL scores were evaluated through Poisson regression and the results were presented as rate ratios (RR) and 95% confidence intervals (CI). The mean overall UW-QOL score was 67.90 (± 18.71). Moderate and high SOC scores were associated with higher mean UW-QOL scores, that is, individuals with a stronger SOC demonstrated better QoL, (p < 0.05). Regarding the clinical variables, individuals with advanced stage cancer and those with hyposalivation and trismus had poorer QoL (p < 0.05). Patients with a greater SOC reported a better quality of life. Our findings show the importance of focusing on psychosocial factors, which can alleviate the impact caused by the disease and improve the QoL of these patients.


Asunto(s)
Carcinoma de Células Escamosas/psicología , Neoplasias de Cabeza y Cuello/psicología , Calidad de Vida/psicología , Sentido de Coherencia , Anciano , Carcinoma de Células Escamosas/patología , Estudios Transversales , Femenino , Neoplasias de Cabeza y Cuello/patología , Humanos , Masculino , Persona de Mediana Edad , Estadificación de Neoplasias , Valores de Referencia , Análisis de Regresión , Índice de Severidad de la Enfermedad , Factores Socioeconómicos , Estadísticas no Paramétricas , Encuestas y Cuestionarios , Trismo/psicología , Xerostomía/psicología
3.
Am J Occup Ther ; 74(1): 7401185020p1-7401185020p9, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32078507

RESUMEN

IMPORTANCE: Evidence supports interventions for social participation for older adults with low vision. OBJECTIVE: This systematic review examined the evidence for interventions within the scope of occupational therapy practice to maintain, restore, and improve performance and quality of life in leisure and social participation for older adults with low vision. DATA SOURCES: MEDLINE, PsycINFO, CINAHL, OTseeker, and the Cochrane Database of Systematic Reviews were searched for articles published from January 2010 to March 2017 that described interventions within the scope of occupational therapy practice for older adults with low vision (mean age 55+). STUDY SELECTION AND DATA COLLECTION: Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) guidelines were followed and applied for this review. Exclusion criteria included publications outside of the period of the study, participants with mean age <55 yr, and interventions outside the occupational therapy scope of practice. FINDINGS: The search yielded 455 articles, of which 3 Level III studies met the inclusion criteria. Low evidence with high risk of bias was found for interventions supporting social participation. Group therapy, more hours of direct service over a shorter duration, and fitting with low vision devices resulted in improvements in social participation and other outcomes. CONCLUSION AND RELEVANCE: Little evidence exists to support occupational therapy interventions in the areas of leisure and social participation. More research is needed in these areas. WHAT THIS ARTICLE ADDS: There continues to be a need for research studies in the areas of leisure and social participation.


Asunto(s)
Terapia Ocupacional , Baja Visión , Anciano , Humanos , Actividades Recreativas , Persona de Mediana Edad , Calidad de Vida/psicología , Participación Social
4.
West Afr J Med ; 37(1): 62-66, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32030714

RESUMEN

BACKGROUND: Acne vulgaris is a chronic inflammatory disease of the pilo-sebaceous unit. It affects teenagers and young adults. Factors which can provoke or aggravate acne include cosmetic agents, medications, and sunlight. Acne has been associated with intense emotional and psychological distress. AIMS: This study aimed to describe predisposing factors, clinical characteristics and the quality of life of students with acne in an undergraduate community. METHODS: This is a cross sectional descriptive study of students of Babcock University, located in the South-Western Nigeria. Data was collected at the residential halls using structured questionnaire which consists of students' demographic data, symptoms, predisposing factors, previous treatment, Cardiff Acne Disability Index; and examination findings to document the presence of acne and clinical characteristics. RESULTS: Acne vulgaris was documented in 391 students (88.5%). Age range of respondents was between 15 and 35, and mean age was 19.51 + 2.25 years. The mean duration of symptoms was 47.46 + 38.27 months. Factors perceived to precipitate acne include food, stress, cleansers and sugary drinks. The mean CADI score for all respondents was 3.27 +3.07 which represents a mild effect on the quality of life. There was no significant difference in the severity of acne in males and females. CONCLUSION: This study documents a high prevalence of acne, although it has only a mild effect on the quality of life of the students. In view of the high percentage of students with acne, it should be penned down for public health intervention to prevent mismanagement, progression and complications.


Asunto(s)
Acné Vulgar/epidemiología , Calidad de Vida/psicología , Estudiantes/estadística & datos numéricos , Acné Vulgar/psicología , Adolescente , Adulto , Estudios Transversales , Femenino , Humanos , Masculino , Nigeria/epidemiología , Prevalencia , Índice de Severidad de la Enfermedad , Distribución por Sexo , Estrés Psicológico/epidemiología , Estudiantes/psicología , Encuestas y Cuestionarios , Adulto Joven
5.
Health Qual Life Outcomes ; 18(1): 1, 2020 Jan 02.
Artículo en Inglés | MEDLINE | ID: mdl-31898546

RESUMEN

BACKGROUND: Well-adapted and validated quality-of-life measurement models for the nursing home population are scarce. Therefore, the aim of this study was to test the psychometrical properties of the OPQoL-brief questionnaire among cognitively intact nursing home residents. The research question addressed evidence related to the dimensionality, reliability and construct validity, all of which considered interrelated measurement properties. METHODS: Cross-sectional data were collected during 2017-2018, in 27 nursing homes representing four different Norwegian municipalities, located in Western and Mid-Norway. The total sample comprised 188 of 204 (92% response rate) long-term nursing home residents who met the inclusion criteria: (1) municipality authority's decision of long-term nursing home care; (2) residential time 3 months or longer; (3) informed consent competency recognized by responsible doctor and nurse; and (4) capable of being interviewed. RESULTS: Principal component analysis and confirmative factor analyses indicated a unidimensional solution. Five of the original 13 items showed low reliability and validity; excluding these items revealed a good model fit for the one-dimensional 8-items measurement model, showing good internal consistency and validity for these 8 items. CONCLUSION: Five out of the 13 original items were not high-quality indicators of quality-of-life showing low reliability and validity in this nursing home population. Significant factor loadings, goodness-of-fit indices and significant correlations in the expected directions with the selected constructs (anxiety, depression, self-transcendence, meaning-in-life, nurse-patient interaction, and joy-of-life) supported the psychometric properties of the OPQoL-brief questionnaire. Exploring the essence of quality-of-life when residing in a nursing home is highly warranted, followed by development and validation of new tools assessing quality-of-life in this population. Such knowledge and well-adapted scales for the nursing home population are beneficial and important for the further development of care quality in nursing homes, and consequently for quality-of-life and wellbeing in this population.


Asunto(s)
Hogares para Ancianos , Casas de Salud , Calidad de Vida/psicología , Encuestas y Cuestionarios/normas , Anciano , Anciano de 80 o más Años , Estudios Transversales , Análisis Factorial , Femenino , Evaluación Geriátrica/métodos , Humanos , Masculino , Noruega , Análisis de Componente Principal , Psicometría , Reproducibilidad de los Resultados
6.
Health Qual Life Outcomes ; 18(1): 5, 2020 Jan 06.
Artículo en Inglés | MEDLINE | ID: mdl-31907046

RESUMEN

BACKGROUND: The evidence regarding patient related outcomes in children with infrequent congenital heart defects (I-CHD) is very limited. We sought to measure quality of life (QoL) in children with I-CHD, and secondarily, to describe QoL changes after one-year of follow-up, self-reported by children and through their caregivers' perspective. METHODS: We assembled a cohort of children diagnosed with an I-CHD in a cardiovascular referral center in Colombia, between August 2016 and September 2018. At baseline and at one-year follow-up, a clinical psychology assessment was performed to establish perception of QoL. The Pediatric Quality of Life Inventory (PedsQL) 4.0 scale was used in both general and cardiac modules for patients and for their caregivers. We used a Mann-Whitney U test to compare scores for general and cardiac modules between patients and caregivers, while a Wilcoxon test was used to compared patients' and caregivers' baseline and follow-up scores. Results are presented as median and interquartile range. RESULTS: To date, QoL evaluation at one-year follow-up has been achieved in 112/157 patients (71%). Self-reported scores in general and cardiac modules were higher than the QoL perceived through their caregivers, both at baseline and after one-year of follow-up. When compared, there was no statistically significant difference in general module scores at baseline between patients (median = 74.4, IQR = 64.1-80.4) and caregivers scores (median = 68.4, IQR = 59.6-83.7), p = 0.296. On the contrary, there was a statistical difference in baseline scores in the cardiac module between patients (median = 79.6, IQR = 69.7-87.4) and caregivers (median = 73.6, IQR = 62.6-84.3), p = 0.019. At one-year of follow-up, scores for the general module between patients (median = 72.8, IQR = 59.2-85.9) and caregivers (median = 69.9, IQR = 58.1-83.7) were not statistically different (p = 0.332). Finally, a significant difference was found for cardiac module scores between patient (median = 75.0, IQR = 67.1-87.1) and caregivers (median = 73.1, IQR = 59.5-83.8), p = 0.034. CONCLUSIONS: QoL in children with I-CHD can be compromised. However, children have a better perception of their QoL when compared with their caregivers' assessments. To provide high-quality care, besides a thorough clinical evaluation, QoL directly elicited by the child should be an essential aspect in the integral management of I-CHD.


Asunto(s)
Cardiopatías Congénitas/psicología , Calidad de Vida/psicología , Cuidadores/psicología , Niño , Preescolar , Colombia , Femenino , Estudios de Seguimiento , Humanos , Masculino , Autoinforme
7.
Orv Hetil ; 161(5): 183-192, 2020 Feb.
Artículo en Húngaro | MEDLINE | ID: mdl-31984771

RESUMEN

Introduction: Over the last few years, in the development of neonatology, the limits to which it is possible to sustain the lives of premature babies have been extended, and thus the proportion of survivors with chronic morbidities has increased. Retinopathy of prematurity (ROP), intraventricular haemorrhage (IVH) and bronchopulmonary dysplasia (BPD), all of which deeply influence the quality of life, life expectancy and social integration, are the most significant morbidities among premature newborns. Aim: Description of psychomotor development of low birth weight (<2500 g) premature infants at the age of 2 years, in relation to the most common chronic morbidities. Method: Psychomotor development (Brunet-Lézine scale, 1980) of low-birth-weight preterm infants at the age of 2 years (n = 200) was measured and the neonatal final reports were analysed retrospectively. Results: After age correction, birth weight positively correlated with the developmental quotient (DQ), while the length of stay in hospital correlated negatively. Grades I/II of neonatal IVH were not significant predictors of lower DQ, while the opposite was true for grades III/IV. We identified a similar relationship with the stages of ROP. According to the result of the homogeneity test, we can consider the independent effects of significant diseases. We also observed that the more diagnoses the premature baby received, the more they are at risk of later developmental delay at the age of 2 years. Conclusions: We recommend the early childhood interventions of the most vulnerable children of ≤1500 g birth weight with severe ROP and IVH - to reduce deficiencies in capabilities and prevent future mental and motor difficulties. Orv Hetil. 2020; 161(5): 183-192.


Asunto(s)
Displasia Broncopulmonar , Hemorragia Cerebral Intraventricular , Desarrollo Infantil/fisiología , Recien Nacido Prematuro , Desempeño Psicomotor/fisiología , Calidad de Vida/psicología , Retinopatía de la Prematuridad , Preescolar , Femenino , Humanos , Lactante , Recién Nacido de Bajo Peso , Recién Nacido , Masculino , Morbilidad , Destreza Motora/fisiología , Embarazo , Estudios Retrospectivos
8.
Orv Hetil ; 161(5): 177-182, 2020 Feb.
Artículo en Húngaro | MEDLINE | ID: mdl-31984774

RESUMEN

Introduction: Tenotomy of the tendon of the stapedius and tensor tympani (TT) muscles is a minimal-invasive surgical therapeutic procedure in Ménière's disease (MD). It has been assumed that the TT medializes the stapes into the oval window, resulting in changes in perilymphatic pressures of the inner ear. By cutting the tendons of both middle ear muscles, they affect the pressure dynamics by not augmenting this pressure even further. Aim: The immediate and long-term investigation of the effect of middle ear muscle tenotomy on the quality of life of patients suffering from Ménière's disease, measured by the Dizziness Handicap Inventory (DHI) and the Tinnitus Handicap Inventory (THI). Method: A follow-up study of 22 patients with definite, unilateral Ménière's disease had undergone tenotomy under general or local anesthesia through an endaural approach. Pre- and postoperative DHI values were compared for all patients. Statistical analysis: The statistical analysis was completed by using the IBM SPSS V24 software. Since the parameters did not show normal distribution, non-parametric test (Mann-Whitney U test) was used. The significance level was specified as p<0.05. Results: A statistically significant reduction of DHI scores was noted in all patients. The tinnitus significantly reduced and all of the patients mentioned improved symptoms of MD. Conclusion: Although the follow-up period is short, and the pathomechanism (decrease of stapes medialization in the oval window) is not exactly clear, tenotomy seems to be a successful promising surgical treatment method with a high reduction of dizziness handicap score in conservative therapy-resistant Ménière's disease. Orv Hetil. 2020; 161(5): 177-182.


Asunto(s)
Enfermedad de Meniere/cirugía , Calidad de Vida/psicología , Estapedio/cirugía , Tenotomía/métodos , Tensor del Tímpano/cirugía , Estudios de Seguimiento , Humanos , Enfermedad de Meniere/complicaciones , Enfermedad de Meniere/psicología , Resultado del Tratamiento , Vértigo/etiología
9.
BMC Public Health ; 20(1): 18, 2020 Jan 07.
Artículo en Inglés | MEDLINE | ID: mdl-31910840

RESUMEN

BACKGROUND: The health-related quality of life (HRQoL) of adolescents with CP in low and middle-income countries is often poor, as is the case in Bangladesh. This exploratory study examined what factors predict the proxy-reported HRQoL of adolescents with CP in rural Bangladesh, a typical low- and middle-income country (LMIC). METHODS: Adolescents with CP (10 to 18y) were identified using the Bangladesh Cerebral Palsy Register. HRQoL was assessed using the Cerebral Palsy Quality of Life-Teens proxy-report questionnaire (CPQoL-Teens), adolescent mental health using the Strengths and Difficulty Questionnaire (SDQ) and caregiver mental health using the Depression, Anxiety and Stress Scale (DASS-21). Theoretical and statistical interests (i.e. bivariate analysis, p < 0.05) identified potential predictors which were entered into hierarchical multiple linear regression (HMLR) models in order of clinical significance; HMLR related adolescent clinical characteristics, adolescent and caregiver mental health and proxies of socioeconomic status to CPQoL-Teens dimensions. RESULTS: One hundred fifty-four adolescents with CP (mean age 15y 1mo, SD 1y 8mo, female 31.2%) participated in this study. Twenty-four factors were identified to explore for relationship to adolescent proxy-reported HRQoL. Fifteen of the factors correlated to one or more CPQoL-Teens dimension; strongest correlation was between 'feelings about functioning' and motor impairment (r = 0.545). Nine were predictive of CPQoL-Teens dimensions; adolescent sex, school attendance, severity of motor impairment, hearing and speech impairment, mother's education, primary caregiver depression and stress, and having a sanitary latrine at home resulting in score changes of between 0.79 (95% CI 0.24 to 1.35) to 35.1 (95% CI 6.03 to 64.22). CONCLUSIONS: Many of the factors predicting the proxy-reported HRQoL of adolescents with CP are amenable to intervention, and have the potential to improve adolescent wellbeing. Several determinants are priorities of the sustainable development goals (SDGs); these findings should inform resource prioritization to improve the wellbeing of adolescents with CP in Bangladesh and other LMICs.


Asunto(s)
Cuidadores/psicología , Parálisis Cerebral/psicología , Áreas de Pobreza , Calidad de Vida/psicología , Población Rural/estadística & datos numéricos , Adolescente , Bangladesh , Femenino , Humanos , Masculino , Análisis Multivariante , Encuestas y Cuestionarios
10.
Integr Cancer Ther ; 19: 1534735419890682, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-31957499

RESUMEN

Background: There is a paucity of research on the long-term impact of stress-reduction in Hispanic/Latina breast cancer (BC) survivors, a growing minority. In this article, we assess the long-term efficacy of an 8-week training program in mindfulness-based stress reduction (MBSR) on quality of life (QoL) in Hispanic BC survivors. Methods: Hispanic BC survivors, within the first 5 years of diagnosis, stages I to III BC, were recruited. Participants were enrolled in bilingual, 8-week intensive group training in MBSR and were asked to practice a- home, daily. They were also provided with audio recordings and a book on mindfulness practices. Patient-reported outcomes for QoL and distress were evaluated at baseline, and every 3 months, for 24 months. Results: Thirty-three self-identified Hispanic women with BC completed the MBSR program and were followed at 24 months. Statistically significant reduction was noted for the Generalized Anxiety Disorder measure (mean change -2.39, P=0.04); and Patient Health Questionnaire (mean change -2.27, P=0.04), at 24 months, compared with baseline. Improvement was noted in the Short-Form 36 Health-related QoL Mental Component Summary with an increase of 4.07 (95% confidence interval = 0.48-7.66, P=0.03). However, there was no significant change in the Physical Component Summary. Conclusions: Hispanic BC survivors who participated in an 8-week MBSR-based survivorship program reported persistent benefits with reduced anxiety, depression, and improved mental health QoL over 24 months of follow-up. Stress reduction programs are beneficial and can be implemented as part of a comprehensive survivorship care in BC patients.


Asunto(s)
Neoplasias de la Mama/terapia , Supervivientes de Cáncer/psicología , Hispanoamericanos/psicología , Atención Plena/métodos , Calidad de Vida/psicología , Estrés Psicológico/terapia , Adaptación Psicológica , Adulto , Neoplasias de la Mama/etnología , Neoplasias de la Mama/psicología , Femenino , Hispanoamericanos/estadística & datos numéricos , Humanos , Salud Mental , Persona de Mediana Edad , Estadificación de Neoplasias , Medición de Resultados Informados por el Paciente , Sentido de Coherencia , Estrés Psicológico/psicología , Resultado del Tratamiento
11.
Crit Rev Oncol Hematol ; 146: 102877, 2020 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-31981880

RESUMEN

BACKGROUND: In this study, our aim was to describe quality of life (QoL) prevalence and heterogeneity in QoL reporting in colorectal cancer phase III trials. METHODS: We included all phase III trials evaluating anticancer drugs in colorectal cancer patients published between 2012 and 2018 by 11 major journals. RESULTS: Out of the 67 publications identified, in 41 (61.2 %) QoL was not listed among endpoints. Out of 26 primary publications of trials including QoL among endpoints, QoL results were not reported in 10 (38.5 %). Overall, no QoL data were available in 51/67 (76.1 %) primary publications. In particular, in the metastatic setting, QoL data were not available in 12/18 (66.7 %) trials with primary endpoint overall survival, and in 20/29 (69.0 %) trials with other primary endpoints. CONCLUSIONS: QoL was absent in a high proportion of recently published phase III trials in colorectal cancer, even in trials of second or further lines, where attention to QoL should be particularly high.


Asunto(s)
Antineoplásicos/uso terapéutico , Ensayos Clínicos Fase III como Asunto , Neoplasias del Colon/tratamiento farmacológico , Neoplasias del Colon/psicología , Neoplasias Colorrectales/tratamiento farmacológico , Neoplasias Colorrectales/psicología , Calidad de Vida/psicología , Neoplasias del Colon/patología , Neoplasias Colorrectales/patología , Humanos , Medición de Resultados Informados por el Paciente , Ensayos Clínicos Controlados Aleatorios como Asunto , Resultado del Tratamiento
12.
Epidemiol Psychiatr Sci ; 29: e85, 2020 Jan 09.
Artículo en Inglés | MEDLINE | ID: mdl-31915097

RESUMEN

Given the high prevalence (30-35%) of psychosocial and psychiatric morbidity amongst cancer patients in any phase of the disease trajectory, screening for emotional problems and disorders has become mandatory in oncology. As a process, screening begins at the entry to the cancer care system and continues at clinically meaningful times, periodically during active cancer care, or when clinically indicated. The goal is to facilitate proper referral to psychosocial oncology specialists for more specific assessment and care, as well as treatment and evaluation of the response, according to the implementation of distress management guidelines. In this editorial, we will provide a non-exhaustive overview of relevant protocols, with particular reference to the National Comprehensive Cancer Network (NCCN) Distress Management in Oncology Guidelines, and review the challenges and the problems in implementing screening, and the assessment and management of psychosocial and psychiatric problems in cancer centres and community care.


Asunto(s)
Tamizaje Masivo/métodos , Neoplasias/psicología , Estrés Psicológico/diagnóstico , Humanos , Salud Mental , Neoplasias/complicaciones , Guías de Práctica Clínica como Asunto , Calidad de Vida/psicología , Estrés Psicológico/etiología , Estrés Psicológico/terapia
13.
Eur J Endocrinol ; 182(3): 319-331, 2020 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-31958318

RESUMEN

Objective: Acromegaly has a negative influence on health-related quality of life (HRQoL). Previous studies provide limited information on the course of HRQoL during treatment. This study aims to assess the effect of treatment on the course of HRQoL at six predefined time points. Design: This prospective study examines HRQoL in treatment-naive patients before and during the first 2.5 years of acromegaly treatment. Methods: Therapy-naive acromegaly patients completed three validated questionnaires (RAND-36, AcroQoL, and the Appearance Self-Esteem (ASE)) at six predetermined time points before, during, and after treatment. Outcomes were correlated to IGF1 levels and disease control status. Results: Twenty-seven acromegaly patients completed the questionnaires at all time points. After treatment, all patients had controlled acromegaly. Scores of RAND-36 domains General health, Vitality and Health change, and all AcroQoL dimensions (except for Relations) improved during treatment (P ≤ 0.003); the largest changes were detected during the first year. Gender influenced HRQoL scores, since AcroQoL scores significantly improved in males but not in females. Over time, IGF1 levels were negatively correlated with HRQoL. After 2.5 years of follow-up, HRQoL of controlled patients was still lower than in the general population. Conclusion: HRQoL of acromegaly patients was considerably reduced at diagnosis. Disease control was associated with an improvement of HRQoL scores. Males showed a more pronounced improvement than females. The largest changes were detected in the first year of treatment. However, HRQoL during and after treatment remained impaired in acromegaly patients, emphasizing the need of additional support.


Asunto(s)
Acromegalia/psicología , Acromegalia/terapia , Calidad de Vida/psicología , Adulto , Anciano , Femenino , Estado de Salud , Hormonas/deficiencia , Hormona de Crecimiento Humana/sangre , Humanos , Factor I del Crecimiento Similar a la Insulina/análisis , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/psicología , Estudios Prospectivos , Autoimagen , Factores Sexuales , Encuestas y Cuestionarios , Resultado del Tratamiento , Adulto Joven
14.
Health Qual Life Outcomes ; 18(1): 7, 2020 Jan 07.
Artículo en Inglés | MEDLINE | ID: mdl-31910874

RESUMEN

BACKGROUND: Population aging is an important phenomenon for many countries worldwide. Considering the growing trend of aging population in Iran, it is very important to consider beliefs and perceptions of old people about aging. The Aging Perception Questionnaire (APQ) is one of the most common instruments that used to measure aging comprehension. The present study was a methodological inquiry that aimed to examine validity and reliability of the Persian version of the Aging Perception Questionnaire (APQ). METHODS: Forward-backward procedure was used for translation. Content validity and face validity were evaluated qualitatively. In order to evaluate construct validity a cross section study was conducted and both exploratory and confirmatory factor analyses were performed. In order to determine reliability, internal consistency (the Cronbach's alpha) and stability (Intraclass Correlation Coefficient -ICC) were estimated. RESULTS: A total of 500 elderly people attending the community centers in Tehran, Iran were entered in other study and completed the Persian version of the questionnaire. Most elderly were female (52.8%).The mean age of participants was 68.33 (SD ± 6.10) years. The results obtained from exploratory factor analysis showed a four-factors solution (consequences negative, emotional representation, control positive and consequences positive) that jointly explained 52.8% of the total variance observed. In addition the confirmatory factory analysis showed a good fit for the data. Finally, the Cronbach's alpha coefficient of 0.83 ranging from 0.80 to 0.87 was obtained for the whole scale and the subscales. The ICC value of 0.96 ranging from 0.90 to 0.98 was found for the whole scale and the subscales. CONCLUSION: The results indicated that the Persian version of APQ is valid and can be used to measure aging perception in Iran.


Asunto(s)
Envejecimiento/psicología , Calidad de Vida/psicología , Anciano , Estudios Transversales , Análisis Factorial , Femenino , Humanos , Irán , Masculino , Persona de Mediana Edad , Reproducibilidad de los Resultados , Encuestas y Cuestionarios , Traducciones
15.
Postgrad Med ; 132(1): 56-61, 2020 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-31711352

RESUMEN

Context: Chronic pain is highly prevalent in most of the industrialized nations around the world. Despite the documented adverse effects, opioids are widely used for pain management. Cannabinoids, and specifically Cannabidiol, is proposed as an opioid alternative, having comparable efficacy with better safety profile.Objectives: We aim to investigate the impact of full hemp extract cannabidiol (CBD) on opioid use and quality of life indicators among chronic pain patients.Methods: An initial sample of 131 patients was recruited from a private pain management center's investigative population. Ninety-seven patients completed the 8-week study. The primary inclusion criteria included patients between 30 and 65 years old with chronic pain who have been on opioids for at least 1 year. Data were collected at three different time points: baseline, 4, and 8 weeks. Opioid and other medication use were evaluated via the medication and psychiatric treatment receipt. Improvement was evaluated using four indices: Pain Disability Index (PDI-4); Pittsburgh Sleep Quality Index (PSQI), Pain Intensity and Interference (PEG); and Patient Health Questionnaire (PHQ-4).Results: Over half of chronic pain patients (53%) reduced or eliminated their opioids within 8 weeks after adding CBD-rich hemp extract to their regimens. Almost all CBD users (94%) reported quality of life improvements. The results indicated a significant relationship between CBD and PSQI (p = 0.003), and PEG (p = 0.006). There was a trend toward improvement but no significant relationship between CBD use and PHQ and PDI.Conclusion: CBD could significantly reduce opioid use and improve chronic pain and sleep quality among patients who are currently using opioids for pain management.Key Message: This is a prospective, single-arm cohort study for the potential role of cannabinoids as an alternative for opioids. The results indicate that using the CBD-rich extract enabled our patients to reduce or eliminate opioids with significant improvement in their quality of life indices.


Asunto(s)
Analgésicos Opioides/uso terapéutico , Cannabidiol/uso terapéutico , Cannabis , Dolor Crónico/tratamiento farmacológico , Extractos Vegetales/uso terapéutico , Calidad de Vida , Adulto , Anciano , Dolor Crónico/psicología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Fitoterapia/métodos , Calidad de Vida/psicología , Encuestas y Cuestionarios
16.
Postgrad Med ; 132(1): 52-55, 2020 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-31736403

RESUMEN

Introduction: Carpal tunnel syndrome (CTS) is an entrapment neuropathy accounting for up to 90% of nerve compression syndromes. It causes both positive and negative symptoms in the hands. These symptoms, especially pain, can be debilitating, which can in turn have a negative effect on patients' quality of life (QoL). The aim of this cross-sectional case-controlled study was two-fold; to compare the QoL of patients with CTS and subjects without CTS and to determine the effect of pain on QoL in patients with CTS.Methods: All patients underwent nerve conduction studies (NCS) and were classified into mild, moderate, severe. QoL was assessed via the SF-36 questionnaire.Results: Fifty-one patients and 45 age- and gender-matched controls were recruited. Prevalence of pain (determined as scoring 4 or above on a visual analog scale) in CTS was 39.2%. CTS patient health-related QOL scores were significantly reduced (p < 0.001) across all of the SF-36 domains, compared to the healthy control group scores. After adjusting for gender presence of pain was still significantly negatively correlated with scores for physical functioning (beta -0.283, p = 0.036).Conclusions: Patients with CTS have a significantly worse QoL compared to subjects without CTS. In addition, the presence of pain is a significant determinant of physical functioning in patients who have been diagnosed with CTS.


Asunto(s)
Síndrome del Túnel Carpiano/complicaciones , Dolor Crónico/etiología , Calidad de Vida , Síndrome del Túnel Carpiano/psicología , Estudios de Casos y Controles , Dolor Crónico/epidemiología , Dolor Crónico/psicología , Estudios Transversales , Femenino , Humanos , Masculino , Persona de Mediana Edad , Dimensión del Dolor , Prevalencia , Calidad de Vida/psicología , Índice de Severidad de la Enfermedad
17.
Acta Odontol Scand ; 78(1): 74-80, 2020 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-31512936

RESUMEN

Objective: To investigate the relationship between subjective symptoms of orofacial pain and oral health-related quality of life (OHRQoL), as well as psychological distress in population-based middle-aged women.Material and methods: The two study samples comprised 1059 women, 38 and 50 years old, in representative cross-sectional studies. Women with long-lasting, frequent pain or headaches, related to temporomandibular disorders (TMD), with moderate-to-high estimates were analysed in relation to the non-case group. OHRQoL was measured using the Oral Health Impact Profile (OHIP-5). Psychological distress was measured using the Hospital Anxiety and Depression Scale (HADS) and Sense of Coherence (SOC-13).Results: Women with orofacial pain (n = 82, 7.7%) had a significantly higher mean score on the OHIP-5, HADS-A and HADS-D and a lower mean score for SOC-13. In a multivariable logistic regression, orofacial pain was statistically significantly associated with poorer OHRQoL (OR = 1.2) and signs of depression (HADS-D) (OR = 2.0). A higher score for SOC-13 protected from the experience of orofacial pain (OR = 0.95).Conclusion: Orofacial pain was associated with poorer OHRQoL and signs of psychological distress. In interpreting the value of SOC, women with orofacial pain also appear to have a poorer adaptive capacity.


Asunto(s)
Dolor Facial/psicología , Salud Bucal , Calidad de Vida/psicología , Trastornos de la Articulación Temporomandibular/psicología , Adulto , Estudios Transversales , Dolor Facial/epidemiología , Femenino , Estado de Salud , Humanos , Persona de Mediana Edad , Trastornos de la Articulación Temporomandibular/fisiopatología , Odontalgia/fisiopatología
18.
Psychiatr Hung ; 35(1): 20-29, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-31854319

RESUMEN

BACKGROUND: The measure of health-related quality of life (HRQoL) among children with mental disorders is still in early ages, even though the worldwide-pooled prevalence of psychiatric diagnoses among children and adolescents is around 13%. Several studies confirmed that these children have impaired social and school functioning and low HRQoL. Mental disorders among children often remain undiagnosed or diagnosed too late, in that case additional negative effects could be expected. The aim of the current study was to identify psychiatric disorders in children who participated in a clinical study as a "healthy" control group and measure its effects on HRQoL. METHODS: The inclusion criteria for control participated children were not having ongoing or previous psychiatric or psychological treatment. In the second step control children (n=79, age range 6-15) were divided into two subgroups according to achieved diagnostic criteria. Measures were Mini International Neuropsychiatric Interview Kid and Inventory for the Assessment of the Quality of Life in Children and Adolescents. For data analyzing due to unequal sample sizes robust Welch t-test with omega squared, Spearman's rank correlation coefficients and logistic regression were applied. RESULTS: According to the children and parents control group with diagnoses have lower HRQoL in school, peer relationships and mental health dimensions than control group without diagnoses. Furthermore, by the children's report this difference exists in the domain of time spent alone, by the parent proxy report exist in the somatic health and general dimensions. An increasing number of diagnoses decreased HRQoL in most areas. The presence of psychiatric diagnoses by children increase 8 times more likely to have low HRQoL in the domain of school and 4 times in the domain of time spent alone. CONCLUSIONS: These results draw attention to the relative high ratio of undiagnosed mental disorders in the control group and for the low HRQoL of these children. Screening of psychiatric disorders in schools should be crucial and the earliest recourse of treatment in the identified children. The findings of this study also underline the importance of assessing HRQoL from different perspectives.


Asunto(s)
Grupos Control , Estado de Salud , Trastornos Mentales/diagnóstico , Trastornos Mentales/psicología , Calidad de Vida/psicología , Adolescente , Niño , Humanos , Padres
19.
Maturitas ; 131: 1-7, 2020 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-31787141

RESUMEN

OBJECTIVE: Recent studies have reported associations between dietary intake and mental health. Dietary fiber is one nutrient that may modulate mental health, specifically depression risk, through the gut microbiome. We prospectively examined the association between dietary fiber intake and mental health-related quality of life (QOL) scores, a proxy for depressive symptoms, in a cohort of 14,129 post-menopausal women in the Iowa Women's Health Study. METHODS: Dietary intake was assessed at baseline [1986] using a 127-item food frequency questionnaire. Mental health-related QOL scores were assessed at the follow-up questionnaire [2004] using the Mental Health (MH) component and Mental Health Composite (MCS) scales derived from the SF-36 Health Survey. The association between dietary fiber intake and mean QOL scores was examined using linear regression, with adjustment for age, alcohol intake, energy intake, waist-to-hip ratio, physical activity, smoking status, and education. RESULTS: The median dietary fiber intake was 19.0 g/day, ranging from 1.1 to 89.4 g/day. Multivariable-adjusted mean MH scores were higher among those with higher fiber intake (P for trend = 0.02). For MCS score, the association with fiber intake observed in a model adjusted for age and energy intake became insignificant after multivariable adjustment. CONCLUSIONS: Our study is one of the first prospective analyses of the association between higher dietary fiber intake and increased MH QOL scores later in life. Given a plausible biological mechanism underlying the association between fiber intake and mental health, additional studies are warranted.


Asunto(s)
Encuestas sobre Dietas , Dieta/estadística & datos numéricos , Fibras de la Dieta/análisis , Encuestas Epidemiológicas , Salud Mental , Salud de la Mujer , Anciano , Depresión , Ingestión de Energía , Femenino , Estudios de Seguimiento , Estado de Salud , Humanos , Iowa , Persona de Mediana Edad , Estudios Prospectivos , Calidad de Vida/psicología , Encuestas y Cuestionarios
20.
Spine (Phila Pa 1976) ; 45(1): E25-E36, 2020 Jan 01.
Artículo en Inglés | MEDLINE | ID: mdl-31842109

RESUMEN

STUDY DESIGN: Prospective cross-sectional case-control study design. OBJECTIVE: This study aims to analyze the relation between balance control as well as health-related quality of life (HRQOL) in patients with adult spinal deformity (ASD), with a novel gravity line (GL)-related 3D spinal alignment parameter, the transverse gravitational deviation index (TGDI), defined to quantify the transverse plane position of any vertebra with respect to the GL. SUMMARY OF BACKGROUND DATA: Demographic data and balance control have both been identified as important determinants of HRQOL in ASD patients during a preoperative setting. Therefore, a better understanding of the relation between spinal alignment and balance is required. METHODS: After informed consent, 15 asymptomatic healthy volunteers (mean age 60.1 ±â€Š11.6 years old) and 55 ASD patients (mean age 63.5 ±â€Š10.1 years old) were included. Relation between performance on BESTest as well as core outcome measures index (COMI) with spinopelvic alignment was explored using General Linear Modeling (GLM). A P-value ≤0.05 was considered statistically significant. RESULTS: The L3 TGDI was identified to relate to balance control in the total ASD population after correction for confounding demographic factors (P = 0.001; adjusted R = 0.500) and explained 19% of the observed variance in balance performance. In addition, COMI is related to L3 TGDI in a subgroup of ASD patients with combined coronal and sagittal malalignment of L3 (P = 0.027; slope B = 0.047), despite significant influence of age (P = 0.020). CONCLUSION: In ASD patients with a combined coronal and sagittal malalignment of the L3 vertebra, both the level of balance impairment as well as HRQOL are related to the distance component of the L3 TGDI, that is, the offset between the center of the L3 vertebral body and the GL in the transverse plane. LEVEL OF EVIDENCE: 2.


Asunto(s)
Gravitación , Balance Postural , Calidad de Vida/psicología , Enfermedades de la Columna Vertebral/epidemiología , Adulto , Anciano , Estudios de Casos y Controles , Estudios Transversales , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Enfermedades de la Columna Vertebral/psicología , Columna Vertebral
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