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1.
Braz. j. oral sci ; 20: e219022, jan.-dez. 2021. ilus
Artículo en Inglés | LILACS, BBO - Odontología | ID: biblio-1254545

RESUMEN

Minimally invasive dentistry is based on conservative techniques for the treatment of initial caries lesions, the so-called white spot lesions. One of the conservative maneuvers includes the use of enamel resin infiltrant: a low viscosity material that penetrates the enamel pores to stop lesion progression. Aim: Therefore, this case report aimed to describe the clinical case of a 28-year-old female patient under routine consultation, in which a radiographic examination showed the presence of two incipient caries lesions in the left upper premolars. Methods: The application of a resin infiltrating agent (Icon®, DMG ­ Hamburg, Germany) was chosen as treatment to stop caries lesions progression. Conclusion: The use of this conservative technique can be considered a promising approach for the prevention of dental tissue wear, and the resin infiltrant is considered an effective material


Asunto(s)
Humanos , Femenino , Resinas Compuestas , Caries Dental , Tratamiento Conservador
2.
Braz. j. oral sci ; 20: e212755, jan.-dez. 2021. ilus
Artículo en Inglés | LILACS, BBO - Odontología | ID: biblio-1254632

RESUMEN

Aim: To investigate restorative decisions made by dentists and to examine what demographic characteristics are associated with the decisions for managing approximal and occlusal lesions. Methods: A questionnaire was randomly sent to 900 Palestinian dentists. It noted the demographic details of the dentists and the years of experience. The questionnaire evaluated the respondents for their treatment decisions regarding approximal and occlusal carious lesions. The data was analyzed using the IBM SPSS statistics for windows. The associations between gender and years of experience of the respondents and their restorative decisions were assessed. Results: The response rate was 58.2%. For occlusal carious lesions, 93.9% of the respondents would postpone operative treatment until the lesion was in dentine (grade 3 to 5). For approximal lesions, intervention was deemed appropriate by 92.6% of the respondents when there was radiographic evidence of a carious lesion reaching the DEJ or deeper. Around 53% preferred to prepare approximal lesions according to the traditional principles of cavity preparation. For both approximal and occlusal lesions, the participants opted for resin composites. Statistically, there was a significant association between the restorative decisions with the years since graduation and gender. Conclusion: The study showed variations between the treatment decisions of Palestinian dentists. The subjects chose conservative treatment plans but still adhered to traditional learned practices especially when cavity preparation for approximal lesions was concerned. The years since graduation and gender played a significant role in the choice of treatment opted for. Resin composites seemed to be a popular choice for treatment


Asunto(s)
Humanos , Masculino , Femenino , Características de la Población , Encuestas y Cuestionarios , Resinas Compuestas , Pautas de la Práctica en Odontología , Caries Dental , Preparación de la Cavidad Dental
3.
Braz. j. oral sci ; 20: e211359, jan.-dez. 2021. ilus
Artículo en Inglés | LILACS, BBO - Odontología | ID: biblio-1252506

RESUMEN

Aim: To evaluate the effects of an intervention for the prevention of obesity on the prevalence of dental caries disease in Spanish children. Methods: Two cities participated intervention study nested in a cohort IDEFICS (Identification and prevention of dietary and lifestyle induced health effects in children and infants): Huesca, where there was a 2-year intervention, which encouraged less sugar consumption; and Zaragoza (control). The prevalence of caries was evaluated by examining the 1st permanent molars in the 7-11 age range, using the ICDAS (International Caries Detection and Assessment System). These teeth erupt at 6 years of age and at the baseline (2007-2008) were free of caries because they were not present in the oral cavity. As outcomes, white spots were selected, combining the ICDAS criteria 1 and 2, and untreated caries, combining criteria 4, 5 and 6. Their association with socioeconomic variables, BMI (Body Mass Index), frequency of sugar intake, sex and parents' perceptions of their children, was investigated. To do so, the chi-square test was applied (p<0.05). Results: The sample consisted of 281 children. The prevalence of white spots and untreated caries was higher in Huesca, despite the intervention. There was no association between the outcomes and the variables studied (p>0.05). Conclusion: The intervention for the prevention of obesity did not exert any association with the prevalence of caries in Spanish children


Asunto(s)
Humanos , Masculino , Femenino , Niño , Salud Bucal , Caries Dental/epidemiología , Obesidad
4.
Braz. j. oral sci ; 20: e211606, jan.-dez. 2021. tab
Artículo en Inglés | LILACS, BBO - Odontología | ID: biblio-1253158

RESUMEN

Aim: The present study sought to investigate dental caries experience and its association with sociodemographic, postnatal and breastfeeding variables in children in the agerange from 6 to 71 months of age, in the Xingu Indigenous Park, Mato Grosso, Brazil. Methods: This was an analytical cross-sectional study that used secondary data pertaining to 402 indigenous children of the Low, Middle and Eastern Xingu regions, who participated in the Oral Health Epidemiological Survey in 2013. The dependent variable was dental caries, dichotomized by the median (dmf-t≤1 and dmf-t>1). The data of independent variables were obtained by means of instruments of the Local Health Information System of the Xingu Indigenous Special Sanitary District (DSEI). Raw analyses were performed to test the association of the independent variables with the dependent variable. The variables were tested in the multiple logistic regression model. Results: The mean value of the dmf-t index was 2.60 and the prevalence of affected children was 51%. In the multiple analysis, only children older than 36 months (OR: 6.64; CI95%: 4.11 to 10.73) and those that were breastfed for a longer period of time (OR: 1.88; CI95%: 1.16 to 3.02) showed significant association with the dmf-t>1 index. Conclusion: Childhood dental caries among indigenous children was associated with age and breastfeeding prolonged for over 26 months, therefore, pointing out the need to offer dental follow-up care at earlier ages


Asunto(s)
Humanos , Masculino , Femenino , Preescolar , Lactancia Materna , Indios Sudamericanos , Salud Bucal , Caries Dental
5.
Braz. j. oral sci ; 20: e210328, jan.-dez. 2021. ilus
Artículo en Inglés | LILACS, BBO - Odontología | ID: biblio-1253738

RESUMEN

Aim: The in vitro study evaluated the effect of different concentrations of green tea extract solution (GT) on the bonding durability of etch-and-rinse adhesive system to caries dentin affected (CAD). Methods: Dentinal surfaces of human third molars were polished and submitted to a microbiological caries induction protocol for 14 days. After removal of the infected dentin layer, the samples were randomly divided into 4 groups (n= 10), according to the concentration of GT solution applied in CAD, after acid etching: 0.05%; 0.2%; 2% and NT (no treatment ­ control). After application of a etch-and-rinse adhesive system (Adper Single Bond 2, 3M ESPE), composite resin restorations were performed on the dentin. After 24 hours, the resin-dentin blocks were sectioned 1mm2 specimens, which were subjected to the microtensile test immediately or after 6 months of storage in water. Data were submitted to two-way ANOVA for randomized blocks and Tukey test (α= 5%). Results: There was no effect of double interaction (p= 0.934). The application of 0.2% GT promoted a statistically significant increase in dentin bond strength values in comparison to the condition where GT was not used (p=0.012). There was a significant decrease of bond strength after 6 months of storage, regardless of dentin pretreatment (p = 0.007). The G test identified that there was no statistical difference regarding failure mode (p= 0.326). Conclusion: The concentration of 0.2% improved the bond strength of an etch-and-rinse adhesive system to caries affected dentin, however, none of dentin pretreatments could prevent the decrease in bond strength over time


Asunto(s)
Resistencia a la Tracción , Camellia sinensis , Caries Dental , Dentina
6.
Braz. j. oral sci ; 20: e211168, jan.-dez. 2021. ilus
Artículo en Inglés | LILACS, BBO - Odontología | ID: biblio-1254279

RESUMEN

Aim: The aim of this study was to evaluate caries diagnosis and treatment decisions made by undergraduate dental students based on ICDAS or Nyvad criteria. Methods: Twelve students analyzed 90 digital photographs of permanent teeth at different clinical stages of carious lesion development and chose among different treatments in three different assessments: when there was no knowledge of the criteria (described as "No knowledge (N)"; when there was theoretical knowledge of the criteria (described as "Theoretical knowledge (T)" and when there was theoretical knowledge, clinical experience about dental caries and the criteria (described as "Theoretical and clinical knowledge (TC)". For "T" and "TC" the students were randomized into two experimental groups ­ ICDAS or Nyvad (experimental units: 6 students/group). The reference standard was established cooperatively by two experienced researchers. Criteria performance was evaluated by sensitivity, specificity, AUC, and Kappa statistics. Treatment decision was described in percentage by contingency tables and Spearman's correlation with the reference standard. Results: The first assessment demonstrated a high percentage of operative treatment even for initial enamel lesions based on ICDAS criteria and treatment was proposed for both active and inactive lesions, according to the Nyvad criteria. In the second assessment, the students continued recommending treatments for initial or inactive lesions, but less frequently. In the third assessment, treatment decisions presented greater cohesion in relation to the assigned classification criterion. The criteria presented no differences between them in terms of diagnostic in the third assessment. Conclusion: Clinical experience may improve caries detection and treatment decisions with the use of ICDAS and Nyvad criteria


Asunto(s)
Enseñanza , Caries Dental/diagnóstico por imagen
7.
Zhonghua Yu Fang Yi Xue Za Zhi ; 55(9): 1129-1132, 2021 Sep 06.
Artículo en Chino | MEDLINE | ID: mdl-34619932

RESUMEN

In 2019, the rate of primary tooth caries rate among 1 598 preschool children in Shinan District and Shibei District of Qingdao was 59.4%. The multivariate logistic regression model showed that compared with children ≤ 2 years old with history of iron deficiency anemia (IDA), suffering IDA, breastfeeding to 2 years old and no tooth melanin, children ≤ 2 years old without history of IDA, not suffering IDA, breastfeeding to less than 2 years old and heavy tooth melanin had a lower risk of primary tooth caries, with OR (95%CI) values about 0.328 (0.197-0.549), 0.354 (0.208-0.603), 0.636 (0.437-0.926) and 0.301 (0.143-0.635), respectively.


Asunto(s)
Caries Dental , Preescolar , Caries Dental/epidemiología , Humanos , Modelos Logísticos , Prevalencia , Diente Primario
8.
J Med Life ; 14(4): 570-577, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34621384

RESUMEN

Studies of the dental status of children with cerebral palsy (CP) indicate a high prevalence and intensity of damage to the hard tissues of the teeth. The risk of developing dental diseases is known to increase significantly as the severity of neurological symptoms increase. The purpose of the study was to assess the incidence of dental caries using the International Caries Detection and Assessment System (ICDAS II) criteria in children with organic diseases of the nervous system depending on the severity of motor impairment. A number of 122 children (mean age 8.8±3.7 years) with spastic forms of cerebral palsy were examined. They were divided into groups according to the Gross Motor Function Classification System - Expanded & Revised (GMFCS-ER). All patients underwent a neurological examination, and the state of dental caries was determined using the ICDAS II criteria. In children with cerebral palsy, lesions of the occlusal surfaces of the teeth predominate, lesions of the proximal surfaces appeared to be three times less, but more than three times higher than in healthy children. Higher intensity of the carious process and the frequency of deep cavities are observed in children with cerebral palsy with severe motor impairment, according to GMFCS-ER. Establishing the features of caries development in children with cerebral palsy depending on the severity of neurological symptoms according to the ICDAS II system is an essential factor in determining the direction of preventive measures that should be taken for this group of children.


Asunto(s)
Caries Dental , Diente , Niño , Caries Dental/epidemiología , Humanos , Sistema Nervioso
9.
Zhonghua Kou Qiang Yi Xue Za Zhi ; 56(1): 3-9, 2021 Jan 09.
Artículo en Chino | MEDLINE | ID: mdl-34645227

RESUMEN

Dental caries is a chronic infectious disease that occurs in the tooth hard tissues. Increasing evidence has also indicated a close involvement of dental caries in the onset and development of systemic diseases. In recent years along with the advances in high throughput-omics technologies, disease animal models, multicenter clinical studies, as well as the research and development in novel dental materials, digital and minimal invasive clinical techniques, robust progress have been made in the field of etiology, pathogenesis, diagnosis, prevention and treatment of dental caries. More importantly, the strategy of whole life cycle management of caries has promoted the combinatory management of dental caries and other systemic chronic diseases, and it has also shed light on the age-based management and risk-control-oriented personalized treatment of caries. In the future, more efforts should be warranted to further the basic research and accelerate its clinical application, so as to advance the early diagnosis, comprehensive prevention and functional-aesthetic treatment with minimal invasive intervention of carious teeth, and ultimately to promote the population-based whole lifecycle management of caries.


Asunto(s)
Caries Dental , Caries Dental/etiología , Caries Dental/terapia , Diagnóstico Precoz , Estética Dental , Humanos
10.
Zhonghua Kou Qiang Yi Xue Za Zhi ; 56(1): 10-15, 2021 Jan 09.
Artículo en Chino | MEDLINE | ID: mdl-34645228

RESUMEN

The development of dental caries is affected by various factors. Patient's general health status can affect the risk of caries. Some systemic diseases may improve caries incidence or cause dental caries by changing oral microenvironment, affecting salivary gland function and salivary composition, and destroying dental structure directly or indirectly. The clinical symptoms and signs of caries associated with systemic diseases are different from common caries and this type of caries has its special strategy of prevention and therapy. The present review article analyzes the causes and mechanisms of caries susceptibility in patients receiving systemic therapy and systematically introduce the modern concepts of caries prevention and management in systemic therapy.


Asunto(s)
Susceptibilidad a Caries Dentarias , Caries Dental , Caries Dental/etiología , Caries Dental/prevención & control , Humanos , Incidencia
11.
Zhonghua Kou Qiang Yi Xue Za Zhi ; 56(1): 16-21, 2021 Jan 09.
Artículo en Chino | MEDLINE | ID: mdl-34645229

RESUMEN

Caries-derived dental pulp diseases are characterized with high incidence and serious endangerment. Considering the complexity of the pulpal infection and the limitation of the pulp self-repairing capability, it is still an urgent problem that how to eradicate infection and to promote tissue regeneration subsequently for dental clinicians. This review discusses and prospects on the pathogenesis, diagnosis and treatment strategies of caries-derived dental pulp diseases, so as to provid a reference on diagnosis and treatment of such diseases for the clinicians.


Asunto(s)
Caries Dental , Enfermedades de la Pulpa Dental , Caries Dental/diagnóstico , Caries Dental/terapia , Susceptibilidad a Caries Dentarias , Pulpa Dental , Recubrimiento de la Pulpa Dental , Enfermedades de la Pulpa Dental/diagnóstico , Enfermedades de la Pulpa Dental/terapia , Exposición de la Pulpa Dental , Humanos
12.
Zhonghua Kou Qiang Yi Xue Za Zhi ; 56(1): 22-26, 2021 Jan 09.
Artículo en Chino | MEDLINE | ID: mdl-34645230

RESUMEN

Malocclusion is the third most common disease in the human oral cavity, closely behind caries and periodontal diseases. Along with the cultural and socio-economic progress, demands for orthodontic treatment is increasing year by year. However, the early stage caries, a most common complication in patients receiving orthodontic treatment using fixed appliances, has become a serious challenge to the prevention of dental caries and the esthetic outcome of orthodontic treatment. It deserves both dental workers and patients to pay attention and to take preventive and therapeutic measures on this issue.


Asunto(s)
Caries Dental , Maloclusión , Atención Odontológica , Caries Dental/etiología , Caries Dental/prevención & control , Susceptibilidad a Caries Dentarias , Estética Dental , Humanos , Aparatos Ortodóncicos
13.
Zhonghua Kou Qiang Yi Xue Za Zhi ; 56(1): 27-32, 2021 Jan 09.
Artículo en Chino | MEDLINE | ID: mdl-34645231

RESUMEN

With the acceleration of population aging in China, the incidence of root surface caries is increasing year by year. Different from coronal caries, lesions of root surface caries mostly occur on the exposed root surfaces after gingival recession in elderly patients, mainly involving cementum and dentin. Root surface caries shows specificity in the pathogenic characteristics, clinical manifestations, diagnosis, treatment, and prevention. This review mainly summarizes the etiology and prevalence, pathology and clinical manifestations, classification, as well as three-level-prevention of root caries, in order to provide relevant guidance for the clinical prevention and treatment of root caries.


Asunto(s)
Caries Dental , Recesión Gingival , Caries Radicular , Anciano , Caries Dental/prevención & control , Susceptibilidad a Caries Dentarias , Cemento Dental , Humanos , Caries Radicular/prevención & control
14.
Zhonghua Kou Qiang Yi Xue Za Zhi ; 56(1): 33-38, 2021 Jan 09.
Artículo en Chino | MEDLINE | ID: mdl-34645232

RESUMEN

The present review paper summarizes the available technical methods for early detection and diagnosis of dental caries lesions, as well as their clinical application range, advantages and disadvantages. Although there are many detection systems supported by new technologies and equipments in clinical practice, current evidence suggests that careful clinical visual and inspection tests, in combination with imagological examination, are still the gold standard for the detection and diagnosis of dental caries.


Asunto(s)
Caries Dental , Caries Dental/diagnóstico , Susceptibilidad a Caries Dentarias , Diagnóstico Precoz , Fluorescencia , Humanos , Sensibilidad y Especificidad , Tomografía de Coherencia Óptica
15.
Zhonghua Kou Qiang Yi Xue Za Zhi ; 56(1): 39-44, 2021 Jan 09.
Artículo en Chino | MEDLINE | ID: mdl-34645233

RESUMEN

Dental caries is a common chronic oral disease of tooth with multiple factor involvement. It has the characteristics of high incidence, low rate of treatment and high rate of retreatment. How to further improve the standardized treatment and management of dental caries has become a clinical problem. Hence, clinical difficulty assessment system of caries prevention and management is established on the base of caries diagnosis and classification. This system mainly includes caries risk assessment and caries treatment evaluation and can provide effective basis for caries management. This review article discusses caries diagnosis and classification, caries risk assessment and caries treatment difficulty assessment, which are the most important parts of caries management in the whole life cycle.


Asunto(s)
Susceptibilidad a Caries Dentarias , Caries Dental , Caries Dental/diagnóstico , Caries Dental/prevención & control , Humanos , Incidencia , Retratamiento , Medición de Riesgo
16.
Zhonghua Kou Qiang Yi Xue Za Zhi ; 56(1): 45-50, 2021 Jan 09.
Artículo en Chino | MEDLINE | ID: mdl-34645234

RESUMEN

With the deep understanding of etiology and pathogenesis, the management of dental caries is no longer limited to restoring the carious lesions. However, based on the assessment of caries risk and carious lesion activity, patient-centered and personalized treatment planning is carried out to regain oral microecological balance, to control caries progression and to restore the structure and function of the carious teeth.


Asunto(s)
Susceptibilidad a Caries Dentarias , Caries Dental , Caries Dental/terapia , Humanos , Planificación de Atención al Paciente , Medición de Riesgo
18.
Arch Oral Biol ; 131: 105265, 2021 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-34601318

RESUMEN

OBJECTIVE: Sodium fluoride (NaF) plays an important role in preventing dental caries. However, the regulatory effect of NaF on the committed differentiation of DPSCs is not fully understood. In this study, we characterized the impact of micromolar levels of NaF on the osteo/odontogenic differentiation of DPSCs. DESIGN: DPSCs were isolated from healthy human third molars and were cultured in conditioned media with different concentrations of NaF. RNA sequencing (RNA-seq) combined with Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis was used to assess the pathways regulated by NaF. Alkaline phosphatase activity, Alizarin red staining, Western blotting, and real-time qRT-PCR were used to determine the osteo/odontogenic differentiation in DPSCs treated with NaF. RESULTS: NaF significantly promoted the osteo/odontogenic differentiation of DPSCs at micromolar levels. Furthermore, RNA-seq and KEGG pathway enrichment analysis indicated that the PI3K/AKT pathway was involved in the pro-osteoclastogenesis effect of NaF. Western blotting analysis exhibited that the phosphorylation of AKT was decreased in NaF-treated DPSCs. Chemical inhibition of the PI3K/AKT pathway abrogated the NaF-promoted DPSCs osteo/odontogenic differentiation. CONCLUSION: Micromolar NaF can promote the osteo/odontogenic differentiation of DPSCs by inhibiting the PI3K/AKT pathway. DATA AVAILABILITY: The data used to support the findings of this study are available from the corresponding author upon request.


Asunto(s)
Caries Dental , Pulpa Dental , Diferenciación Celular , Proliferación Celular , Células Cultivadas , Humanos , Odontogénesis , Osteogénesis , Fosfatidilinositol 3-Quinasas , Proteínas Proto-Oncogénicas c-akt , Fluoruro de Sodio/farmacología , Células Madre
19.
Trials ; 22(1): 687, 2021 Oct 09.
Artículo en Inglés | MEDLINE | ID: mdl-34627344

RESUMEN

BACKGROUND: The traditional spoon-feeding approach to introduction of solid foods during the complementary feeding period is supported by consensus in the scientific literature. However, a method called Baby-Led Introduction to SolidS (BLISS) has been proposed as an alternative, allowing infants to self-feed with no adult interference. To date, there have been no trials in the Brazilian population to evaluate the effectiveness of BLISS in comparison to the traditional approach. METHODS/DESIGN: To evaluate and compare three different complementary feeding methods. Data on 144 mother-child pairs will be randomized into intervention groups by methods: (A) strict Parent-Led Weaning; (B) strict Baby-Led Introduction to SolidS; and (C) a mixed method. Prospective participants from Porto Alegre, Brazil, and nearby cities will be recruited through the Internet. The interventions will be performed by nutritionists and speech therapists, at 5.5 months of age of the child, at a private nutrition office equipped with a test kitchen where meals will be prepared according to the randomized method. The pairs will be followed up at 7, 9, and 12 months of age. Data will be collected through questionnaires designed especially for this study, which will include a 24h child food recall, questionnaires on the child's and parents' eating behavior, oral habits, eating difficulties, and choking prevalence. At 12 months of age, children will undergo blood collection to measure hemoglobin, ferritin, and C-reactive protein, saliva collection for analysis of genetic polymorphisms, and oral examination. Anthropometric parameters (child and maternal) will be measured at the baseline intervention, at a 9 month home visit, and at the end-of-study visit at the hospital. The primary outcome will be child growth and nutritional status z-scores at 12 months; secondary outcomes will include iron status, feeding behavior, acceptability of the methods, dietary variety, choking, eating behaviors, food preferences, acceptance of bitter and sweet flavors, suction, oral habits, oral hygiene behavior, dental caries, gingival health status, and functional constipation. DISCUSSION: The trial intends to ascertain whether there are potential advantages to the BLISS complementary feeding method in this specific population, generating data to support families and healthcare providers. TRIAL REGISTRATION: Brazilian Clinical Trials Registry (ReBEC): RBR- 229scm number U1111-1226-9516 . Registered on September 24, 2019.


Asunto(s)
Caries Dental , Conducta Alimentaria , Humanos , Lactante , Fenómenos Fisiológicos Nutricionales del Lactante , Estudios Prospectivos , Ensayos Clínicos Controlados Aleatorios como Asunto , Destete
20.
Front Cell Infect Microbiol ; 11: 719411, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34646784

RESUMEN

Patients with Crohn's disease frequently develop oral health problems and show a higher prevalence of oral manifestations, such as dental caries and periodontitis, than healthy individuals do. In this study, a metagenomic analysis was carried out to characterize the salivary microbiota in patients with either periodontitis or Crohn's disease-associated periodontitis. Saliva samples were collected from six patients with both Crohn's disease and periodontitis (Cm group), six patients with periodontitis alone (Pm group), and six healthy individuals (Hm group). Genomic DNA was collected from these samples for high-throughput Illumina HiSeq metagenomic sequencing. The composition of the bacterial communities and their metabolic pathways and gene functions were characterized and compared among the three study groups. The salivary microbial communities were significantly different among the three groups, with Firmicutes, Actinobacteria, and Bacteroidetes showing the most significant differences. The Cm and Pm groups had higher abundances of Bacteroides fragilis, Prevotella baroniae, Prevotella enoeca, and Prevotella dentasini than the Hm group. The Cm and Pm groups also showed differences in their salivary microbial communities, in that the Cm group had relatively high abundances of Firmicutes and Proteobacteria, whereas the Pm group had relatively high abundances of Actinobacteria, Bacteroidetes, and Fusobacteria. In total, 34 Pm-associated (e.g., Fusobacteria and Corynebacterium matruchotii), 18 Cm-associated (e.g., Capnocytophaga and Streptococcus oralis), and 18 Hm-associated (e.g., Streptococcus and Bacillales) predominant microbial species were identified. Most genes were involved in carbohydrate and amino acid metabolism, with those of the Cm and Pm groups showing more similarity to one another but significant differences from those of the Hm group. Most of the antibiotic resistance genes were found in the Pm group. In conclusion, the salivary microbial community structure and abundance were distinct among patients with Crohn's disease-associated periodontitis, patients with periodontitis, and healthy individuals. Further studies are needed to evaluate the potential value of these microbiota and microbiome differences in the clinical diagnosis and treatment of oral diseases.


Asunto(s)
Enfermedad de Crohn , Caries Dental , Microbiota , Periodontitis , Corynebacterium , Enfermedad de Crohn/complicaciones , Humanos , Prevotella , ARN Ribosómico 16S/genética , Saliva
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