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1.
BMC Res Notes ; 14(1): 213, 2021 May 31.
Artículo en Inglés | MEDLINE | ID: mdl-34059128

RESUMEN

OBJECTIVES: Cutaneous leishmaniasis is a vector-borne parasitic disease whose lasting scars can cause stigmatization and depressive symptoms. It is endemic in remote rural areas and its incidence is under-reported, while the effectiveness, as opposed to efficacy, of its treatments is largely unknown. Here we present the data management plan (DMP) of a project which includes mHealth tools to address these knowledge gaps in Colombia. The objectives of the DMP are to specify the tools and procedures for data collection, data transfer, data entry, creation of analysis dataset, monitoring and archiving. RESULTS: The DMP includes data from two mobile apps: one implements a clinical prediction rule, and the other is for follow-up and treatment of confirmed cases. A desktop interface integrates these data and facilitates their linkage with other sources which include routine surveillance as well as paper and electronic case report forms. Multiple user and programming interfaces are used, as well as multiple relational and non-relational database engines. This DMP describes the successful integration of heterogeneous data sources and technologies. However the complexity of the project meant that the DMP took longer to develop than expected. We describe lessons learned which could be useful for future mHealth projects.


Asunto(s)
Leishmaniasis Cutánea , Aplicaciones Móviles , Telemedicina , Colombia/epidemiología , Manejo de Datos , Humanos , Leishmaniasis Cutánea/diagnóstico , Leishmaniasis Cutánea/epidemiología
2.
Hist Philos Life Sci ; 43(2): 79, 2021 Jun 03.
Artículo en Inglés | MEDLINE | ID: mdl-34085127

RESUMEN

This short paper aims to present some philosophical considerations about the relationship between credibility and the uses of evidence. The point of view regarding evidence and scientific and political decisions in this paper focuses on the current world situation of the COVID-19.


Asunto(s)
COVID-19/epidemiología , Política , Salud Pública , Política Pública , Factores Socioeconómicos , Colombia/epidemiología , Exactitud de los Datos , Medicina Basada en la Evidencia , Humanos , SARS-CoV-2
3.
Rev Soc Bras Med Trop ; 54: e06122020, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34105635

RESUMEN

INTRODUCTION: Leishmaniasis is strongly associated with armed conflict. We describe the epidemiology of leishmaniasis before and after the peace agreement in Colombia. METHODS: Data for 2004-2019 period were collected from the National Public Health Surveillance System. The annual incidence per geographical department before and after the peace agreement was calculated and correlated with armed conflict severity. RESULTS: The annual incidence of leishmaniasis registered a downfall with an annual percentage change of 17.7% after the peace treaty. CONCLUSIONS: A decrease in hostilities has a positive impact on the leishmaniasis incidence, which may be the case for other public health issues.


Asunto(s)
Leishmaniasis , Colombia/epidemiología , Humanos , Incidencia , Cooperación Internacional , Salud Pública
4.
BMC Ophthalmol ; 21(1): 248, 2021 Jun 05.
Artículo en Inglés | MEDLINE | ID: mdl-34088276

RESUMEN

BACKGROUND: Eye injury is a serious worldwide public health problem that may cause blindness. In children, blindness has functional impact and psychosocial implications. As indicated in many worldwide studies, identification of risk factors associated with the socio-cultural context may prevent eye injuries. The objetive of the study is to describe the sociodemographic and epidemiological characteristics of pediatric eye injury and its effects on ocular structures in a public hospital from Colombia. METHOD: A retrospective cross-sectional study was carried out between January 1, 2015, and December 31, 2017, in a tertiary public hospital of a medium-sized city located in the Northeast of Colombia. Children under 15 years old with trauma to the eyeball or its adnexa were included. The Birmingham Eye Trauma Terminology System (BETTS) was used. Eye burns and Ocular adnexa were also included. RESULTS: 61 cases of eye injuries were recorded, 67.21% (41 cases) of which were males. 57.37% (35 cases) corresponded to closed-globe injuries both contusion and lamellar laceration. Visual acuity fluctuated between 20/20 and 20/40. 14.75% (9 cases) were open-globe injuries while 50% (4 cases) were penetrating trauma. 27.86% of the injuries (17 cases) did not directly compromise the eyeball, 58.82% (10 of these cases) of which corresponded to eyelid wounds, and neither of those had visual acuity information. CONCLUSION: The study showed that the majority of eye injuries in children under 15 years old, from a public hospital in the Northeast of Colombia, are closed globe, caused by blows, and occur in males.


Asunto(s)
Lesiones Oculares , Adolescente , Niño , Colombia/epidemiología , Estudios Transversales , Lesiones Oculares/epidemiología , Femenino , Hospitales Públicos , Humanos , Masculino , Estudios Retrospectivos
5.
Artículo en Inglés | MEDLINE | ID: mdl-34064361

RESUMEN

Bovine leukemia virus (BLV) is the causative agent of leukemia/lymphoma in cattle. It has been found in humans and cattle-derived food products. In humans, it is described as a potential risk factor for breast cancer development. However, the transmission path remains unclear. Here, a molecular epidemiology analysis was performed to identify signatures of genetic flux of BLV among humans, animals, and food products. Sequences obtained from these sources in Colombia were used (n = 183) and compared with reference sequences available in GenBank. Phylogenetic reconstruction was performed in IQ-TREE software with the maximum likelihood algorithm. Haplotype (hap) distribution among the population was carried out with a median-joining model in Network5.0. Recombination events were inferred using SplitsTree4 software. In the phylogenetic analysis, no specific branches were identified for the Colombian sequences or for the different sources. A total of 31 haps were found, with Hap 1, 4, 5 and 7 being shared among the three sources of the study. Reticulation events among the different sources were also detected during the recombination analysis. These results show new insights about the zoonotic potential of BLV, showing evidence of genetic flux between cattle and humans. Prevention and control strategies should be considered to avoid viral dissemination as part of the One Health program policies.


Asunto(s)
Leucosis Bovina Enzoótica , Virus de la Leucemia Bovina , Animales , Bovinos , Colombia/epidemiología , Leucosis Bovina Enzoótica/epidemiología , Leucosis Bovina Enzoótica/genética , Haplotipos , Humanos , Virus de la Leucemia Bovina/genética , Filogenia
6.
Medwave ; 21(3): e8147, 2021 Apr 07.
Artículo en Español, Inglés | MEDLINE | ID: mdl-33955972

RESUMEN

Introduction: The COVID-19 pandemic was declared in early 2020, requiring different prevention and intervention measures on a large scale. In the case of Colombia, a series of measures focused on isolation and remote services provision were introduced in a context marked by health inequities. This article reviews the theoretical and normative references on primary care interventions in the Colombian response to the COVID-19 pandemic. Methods: A literature review was conducted in PubMed, LILACS, MEDLINE, and official documents and regulations issued in Colombia, the World Health Organization, and the Pan American Health Organization. A narrative synthesis was done of 33 documents based on their contribution to the implementation of primary care in Colombia and their role in the pandemic. Results: The information was organized into two categories: Actions taken in Colombia in response to COVID-19 and Opportunities in primary care in response to COVID-19. Colombias actions were contrasted with world experience. Better pandemic control was found in countries that adopted primary care as a response. Primary care has strengthened the handling of the pandemic through community action, the provision of coordinated services, mental health inclusion, and the adoption of telemedicine processes. Conclusions: In Colombia, primary care is presented as an opportunity to respond to the COVID-19 pandemic and the problems and needs derived from this situation. However, despite the above, there is resistance in the country to adopt this type of approach and complement the hospital-centric model to face the pandemic.


Asunto(s)
COVID-19/epidemiología , COVID-19/prevención & control , Pandemias/prevención & control , Atención Primaria de Salud/organización & administración , Atención Ambulatoria , COVID-19/diagnóstico , Colombia/epidemiología , Atención a la Salud/organización & administración , Humanos , Difusión de la Información , Salud Mental , Distanciamiento Físico , Cuarentena/organización & administración , Telemedicina
7.
J Infect Public Health ; 14(6): 696-701, 2021 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-34020208

RESUMEN

INTRODUCTION: Despite the high volume of infections, some clinical aspects of this disease are still unknown. There are currently no studies in Colombia that describe the disease's clinical and treatment aspects in detail. OBJECTIVE: Describe the characteristics and clinical management of a group of admitted patients with SARS-CoV-2 infection in a private clinic in Montería, Córdoba-Colombia. PATIENTS AND METHODS: A descriptive observational study was carried out between May and August 2020 in 209 hospitalized patients with a confirmed diagnosis of COVID-19. Upon admittance, clinical, sociodemographic characteristics, comorbidities, and complications were analyzed. Additionally, the effect of the following medications was described: 1-antibiotics (cefepime, piperacillin, tazobactam, meropenem, vancomycin) + low molecular weight heparin (LMWH) + corticosteroids (dexamethasone-methylprednisolone) + colchicine. 2- Antibiotic + LMWH + corticosteroids. 3-LMWH + corticosteroids. 4-LMWH + corticosteroids + colchicine. 5-Other treatments (Tocilizumab). RESULTS: 107 (51%) of the 209 patients with a confirmed diagnosis of COVID-19 passed away. The main comorbidities related to mortality of these hospitalized patients with COVID-19 were obesity and kidney disease (P < 0.05). The main complications associated with fatal outcomes in this group of patients were Acute Respiratory Distress Syndrome (ARDS) and sepsis (P < 0.05). Furthermore, it was evidenced that the colchicine combination showed a significant difference in reducing mortality in hospitalized patients compared to the other therapeutic regimens (P < 0.05). CONCLUSION: A mortality rate of 51% was found attributable to several factors such as advanced age, obesity, kidney disease, and an average time in days of late consultation. The implementation of the colchicine combination could reduce the mortality rate in this disease.


Asunto(s)
COVID-19 , Región del Caribe , Colombia/epidemiología , Heparina de Bajo-Peso-Molecular , Humanos , SARS-CoV-2
8.
Bogotá; Organización Panamericana de la Salud; abr. 20, 2021. 33 p. ilus..
No convencional en Español | LILACS | ID: biblio-1178359
9.
Bogotá; Organización Panamericana de la Salud; abr. 6, 2021. 30 p. ilus..
No convencional en Español | LILACS | ID: biblio-1178362
10.
Bogotá; Organización Panamericana de la Salud; abr. 13, 2021. 23 p. ilus..
No convencional en Español | LILACS | ID: biblio-1178363
11.
Psychiatr Danub ; 33(1): 101-106, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33857053

RESUMEN

BACKGROUND: Chronic non-communicable diseases, such as asthma (AS) and chronic obstructive pulmonary disease (COPD), are a public health problem that compromises patients' quality of life and is highly comorbid with medical and psychological conditions. The present study's objective was to know the variables associated with the risk of major depression during confinement due to SAR-CoV-2 in patients with AS and COPD in the Colombian Caribbean. SUBJECTS AND METHODS: An online cross-sectional observational study was done with the participation of patients diagnosed with AS or COPD. AS and COPD patients completed the Patient Health Questionnaire (PHQ-9) to identify a major depressive disorder risk. RESULTS: Two hundred seventy-seven patients diagnosed with AS or COPD aged 18 to 69 (M=60.4, SD=17.6) participated. The risk of major depression was assessed using the PHQ-9 sent online after telephone contact with the participants. 30.7% of the patients during the last month reported a risk of major depression, and it was associated with a history of major depressive disorder (OR=4.39, 95% CI 1.53-12.67) and medical comorbidity (OR=1.69, 95% CI 1.00-2.86). CONCLUSIONS: The depression risk is associated with a history of depressive disorder and medical comorbidity in patients with AS and COPD. Medical history is the leading risk factor for depression during confinement. It is recommended to carry out studies with many participants and study other variables that may mediate said associations during confinement by SAR-CoV-2 in the Colombian Caribbean.


Asunto(s)
Asma , Trastorno Depresivo Mayor , Enfermedad Pulmonar Obstructiva Crónica , Adolescente , Adulto , Anciano , Asma/epidemiología , Colombia/epidemiología , Comorbilidad , Estudios Transversales , Depresión , Trastorno Depresivo Mayor/epidemiología , Humanos , Persona de Mediana Edad , Enfermedad Pulmonar Obstructiva Crónica/epidemiología , Calidad de Vida , Factores de Riesgo , Adulto Joven
12.
Artículo en Inglés | MEDLINE | ID: mdl-33920843

RESUMEN

The negative effects of coronavirus disease 2019 (COVID-19) pandemic have impacted the world economy due to the absence from work because of SARS-CoV-2 infection in workers, among other reasons. However, some economic areas are essential to society and people must continue working outside the home to support economic reactivation; their serological profile could be different from that of the global population. Cross-sectional study: Workers from health, construction, public transportation, public force, bike delivery messengers, independent or informal commerce areas, and residents of Bucaramanga or its metropolitan area were invited to participate. All participants self-completed a virtual survey and a blood test was taken to assess IgG and IgM with the ARC COV2 test. Seroprevalence was estimated considering a complex survey design, correcting for a finite population effect and adjusting for test performance. A total of 7045 workers were enrolled; 59.9% were women and most were residents of Bucaramanga and working in health occupations. The global adjusted seroprevalence was 19.5% (CI: 95% 18.6-20.4), being higher for Girón (27.9%; 95% CI: 24.5-31.30). Workers with multiple contact with people during working hours or using public transportation to go to work had a higher frequency of seropositivity for SARS-CoV-2. The seroprevalence among workers living in these four municipalities from the Colombian northeast area is still low.


Asunto(s)
COVID-19 , SARS-CoV-2 , Anticuerpos Antivirales , Colombia/epidemiología , Estudios Transversales , Femenino , Humanos , Masculino , Estudios Seroepidemiológicos
13.
BMC Health Serv Res ; 21(1): 334, 2021 Apr 13.
Artículo en Inglés | MEDLINE | ID: mdl-33849521

RESUMEN

BACKGROUND: Severe bronchiolitis requiring mechanical ventilation was associated with an absence of surfactant activity and phosphatidylglycerol, causing airway obstruction in acute bronchiolitis. Exogen surfactant in mechanically ventilated infants decreased duration of stay in the intensive care unit and had favorable effects on oxygenation and carbon dioxide removal. This study aimed to evaluate the budget impact of surfactant therapy for bronchiolitis in critically ill infants in Colombia. METHODS: Budget impact analysis was performed to estimate the economic impact of surfactant therapy (ST) for the treatment of infants with a diagnosis of bronchiolitis, requiring mechanical ventilation. The analysis considered a 4-year time horizon and Colombian National Health System perspective. The model estimated drug costs associated with current scenario using humidified oxygen or adrenaline nebulization, and new scenario adding exogen surfactant. The size of the target population was calculated using epidemiological national data. Univariate one-way sensitivity analyses and scenario analyses were performed. RESULTS: In the base-case analysis the 4-year costs associated to ST and no-ST were estimated to be US$ 55,188,132 and US$ 55,972,082 respectively, indicating savings for Colombian National Health equal to US$ 783,950 if ST is adopted for the routine management of patients with bronchiolitis requiring mechanical ventilation. In the one-way sensitivity analysis, only increases in the cost of the surfactant drug and cost or length of stay in the pediatric intensive unit reduce the potential savings of ST. CONCLUSION: ST was cost-saving in emergency settings for treating infants with severe bronchiolitis requiring mechanical ventilation. This shift in treatment approach proved to be economically favorable in the Colombian context.


Asunto(s)
Bronquiolitis , Enfermedad Crítica , Bronquiolitis/tratamiento farmacológico , Niño , Colombia/epidemiología , Enfermedad Crítica/terapia , Humanos , Lactante , Tiempo de Internación , Respiración Artificial , Tensoactivos
14.
PLoS Negl Trop Dis ; 15(4): e0009327, 2021 04.
Artículo en Inglés | MEDLINE | ID: mdl-33857136

RESUMEN

BACKGROUND: The SARS-CoV-2 pandemic has forced health authorities across the world to take important decisions to curtail its spread. Genomic epidemiology has emerged as a valuable tool to understand introductions and spread of the virus in a specific geographic location. METHODOLOGY/PRINCIPAL FINDINGS: Here, we report the sequences of 59 SARS-CoV-2 samples from inhabitants of the Colombian Amazonas department. The viral genomes were distributed in two robust clusters within the distinct GISAID clades GH and G. Spatial-temporal analyses revealed two independent introductions of SARS-CoV-2 in the region, one around April 1, 2020 associated with a local transmission, and one around April 2, 2020 associated with other South American genomes (Uruguay and Brazil). We also identified ten lineages circulating in the Amazonas department including the P.1 variant of concern (VOC). CONCLUSIONS/SIGNIFICANCE: This study represents the first genomic epidemiology investigation of SARS-CoV-2 in one of the territories with the highest report of indigenous communities of the country. Such findings are essential to decipher viral transmission, inform on global spread and to direct implementation of infection prevention and control measures for these vulnerable populations, especially, due to the recent circulation of one of the variants of concern (P.1) associated with major transmissibility and possible reinfections.


Asunto(s)
COVID-19/epidemiología , COVID-19/virología , SARS-CoV-2/aislamiento & purificación , COVID-19/etnología , COVID-19/transmisión , Colombia/epidemiología , Humanos , Indios Sudamericanos , SARS-CoV-2/genética , Análisis Espacial , Factores de Tiempo
15.
BMC Public Health ; 21(1): 690, 2021 04 08.
Artículo en Inglés | MEDLINE | ID: mdl-33832452

RESUMEN

BACKGROUND: According to the 2015 National Survey of the Nutritional Situation in Colombia the prevalence of stunting in children under 5 years of age was 10.8%. In terms of region, Bogotá, presented the highest prevalence rate (13%), a figure that exceeded national records. With the collaboration of local and national government, and nongovernmental it was decided to develop a pilot study involving a public health intervention with residents of Bogotá under 1 year of age with nutritional classification by anthropometry compatible with stunting risk or stunting. METHODS: Pre-experimental, before and after study that sought to determine the magnitude of the change in nutritional status through a 10 months public health nutrition intervention in children under one-year-old residing in 3 prioritized territories of Bogotá. RESULTS: The intervention comprised 1126 children living in the following territories in Bogotá: Kennedy, San Cristóbal, and Engativá. A total of 43.3% children presented delay in height for age, and 56.7% presented risk of short stature. In the final measurement, data were obtained from 686 children, identifying that 17% of the children progressed from stunting to a stunting risk and that 4.5% recovered their growth trajectory, achieving an adequate length for their age. CONCLUSION: That children classified as at risk or stunting at the beginning of the intervention showed an increased probability of approaching or being in the appropriate growth trajectory according to the length-for-age indicator after the intervention.


Asunto(s)
Trastornos del Crecimiento , Desnutrición , Niño , Preescolar , Colombia/epidemiología , Trastornos del Crecimiento/epidemiología , Humanos , Lactante , Desnutrición/epidemiología , Persona de Mediana Edad , Estado Nutricional , Proyectos Piloto , Prevalencia
16.
Bogotá; Organización Panamericana de la Salud; mar. 24, 2021. 30 p. ilus..
No convencional en Español | LILACS | ID: biblio-1178360
17.
Bogotá; Organización Panamericana de la Salud; mar. 24, 2021. 14 p. ilus..
No convencional en Español | LILACS | ID: biblio-1178361
18.
Bogotá; Organización Panamericana de la Salud; mar. 2, 2021. 31 p.
No convencional en Español | LILACS | ID: biblio-1151050
19.
Bogotá; Organización Panamericana de la Salud; mar. 9, 2021. 31 p.
No convencional en Español | LILACS | ID: biblio-1151051
20.
Bogotá; Organización Panamericana de la Salud; mar. 16, 2021. 31 p.
No convencional en Español | LILACS | ID: biblio-1151052
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