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1.
Future Microbiol ; 16(11): 769-776, 2021 07.
Artículo en Inglés | MEDLINE | ID: mdl-34253052

RESUMEN

The current study presents two patients who lived in a rural family with close contact and suffered from rapidly progressive pneumonia. Chest computed tomography images and lymphocytopenia indicated the possibility of COVID-19 infection, but antibody and nucleic acid tests excluded this possibility. Negative results were obtained from corresponding tests for pneumococcal, adenovirus, fungal and legionella infection. Metagenomics analysis and subsequent antibody tests confirmed mycoplasma pneumonia. After treating with moxifloxacin, both patients recovered well and left the hospital. In terms of complicated infectious disease, consideration of atypical pathogens and medical and epidemiological history were important for differential diagnosis of COVID-19; metagenomics analysis was useful to provide direct references for diagnosis.


Asunto(s)
Moxifloxacino/uso terapéutico , Neumonía por Mycoplasma/diagnóstico , Adolescente , Adulto , COVID-19 , ADN Bacteriano , Diagnóstico Diferencial , Heces/microbiología , Femenino , Humanos , Masculino , Metagenómica , Mycoplasma pneumoniae/genética , Mycoplasma pneumoniae/aislamiento & purificación , Neumonía por Mycoplasma/tratamiento farmacológico , Esputo/microbiología , Adulto Joven
2.
Chest ; 160(1): e39-e44, 2021 07.
Artículo en Inglés | MEDLINE | ID: mdl-34246387

RESUMEN

CASE PRESENTATION: A 65-year-old man presented with shortness of breath, gradually worsening for the previous 2 weeks, associated with dry cough, sore throat, and diarrhea. He denied fever, chills, chest pain, abdominal pain, nausea, or vomiting. He did not have any sick contacts or travel history outside of Michigan. His medical history included hypertension, diabetes mellitus, chronic kidney disease, morbid obesity, paroxysmal atrial fibrillation, and tobacco use. He was taking amiodarone, carvedilol, furosemide, pregabalin, and insulin. The patient appeared to be in mild respiratory distress. He was afebrile and had saturation at 93% on 3 L of oxygen, heart rate of 105 beats/min, BP of 145/99 mm Hg, and respiratory rate of 18 breaths/min. On auscultation, there were crackles on bilateral lung bases and chronic bilateral leg swelling with hyperpigmented changes. His WBC count was 6.0 K/cumm (3.5 to 10.6 K/cumm) with absolute lymphocyte count 0.7 K/cumm (1.0 to 3.8 K/cumm); serum creatinine was 2.81 mg/dL (0.7 to 1.3 mg/dL). He had elevated inflammatory markers (serum ferritin, C-reactive protein, lactate dehydrogenase, D-dimer, and creatinine phosphokinase). Chest radiography showed bilateral pulmonary opacities that were suggestive of multifocal pneumonia (Fig 1). Nasopharyngeal swab for SARS-CoV-2 was positive. Therapy was started with ceftriaxone, doxycycline, hydroxychloroquine, and methylprednisolone 1 mg/kg IV for 3 days. By day 3 of hospitalization, he required endotracheal intubation, vasopressor support, and continuous renal replacement. Blood cultures were negative; respiratory cultures revealed only normal oral flora, so antibiotic therapy was discontinued. On day 10, WBC count increased to 28 K/cumm, and chest radiography showed persistent bilateral opacities with left lower lobe consolidation. Repeat respiratory cultures grew Pseudomonas aeruginosa (Table 1). Antibiotic therapy with IV meropenem was started. His condition steadily improved; eventually by day 20, he was off vasopressors and was extubated. However, on day 23, he experienced significant hemoptysis that required reintubation and vasopressor support.


Asunto(s)
Aspergillus niger/aislamiento & purificación , COVID-19 , Hemoptisis , Aspergilosis Pulmonar Invasiva , Pseudomonas aeruginosa/aislamiento & purificación , SARS-CoV-2/aislamiento & purificación , Sobreinfección , Voriconazol/administración & dosificación , Anciano , Antifúngicos/administración & dosificación , COVID-19/complicaciones , COVID-19/diagnóstico , COVID-19/fisiopatología , COVID-19/terapia , Deterioro Clínico , Enfermedad Crítica/terapia , Vías Clínicas , Diagnóstico Diferencial , Hemoptisis/diagnóstico , Hemoptisis/etiología , Hemoptisis/terapia , Humanos , Aspergilosis Pulmonar Invasiva/complicaciones , Aspergilosis Pulmonar Invasiva/diagnóstico , Aspergilosis Pulmonar Invasiva/fisiopatología , Pulmón/diagnóstico por imagen , Pulmón/fisiopatología , Masculino , Radiografía Torácica/métodos , Respiración Artificial/métodos , Sobreinfección/diagnóstico , Sobreinfección/microbiología , Sobreinfección/fisiopatología , Sobreinfección/terapia , Tomografía Computarizada por Rayos X/métodos , Resultado del Tratamiento
3.
BMC Infect Dis ; 21(1): 680, 2021 Jul 13.
Artículo en Inglés | MEDLINE | ID: mdl-34256709

RESUMEN

BACKGROUND: Campylobacter fetus is an uncommon Campylobacter species, and its infections mainly cause infective endocarditis, aortic aneurysm, and meningitis rather than enteritis. It is more likely to be detected in blood than Campylobacter jejuni or Campylobacter coli, specifically reported in 53% of patients. In our case, C. fetus was detected in both blood and cerebrospinal fluid (CSF) cultures. CASE PRESENTATION: A 33-year-old woman, who was on maintenance chemotherapy for acute lymphoblastic leukemia (ALL), presented to our clinic with chief complaints of severe headache and nausea. Blood and CSF cultures revealed C. fetus. We administrated meropenem 2 g intravenously (IV) every 8 h for 3 weeks, and she was discharged without neurological sequelae. CONCLUSION: We encountered a case of C. fetus meningitis without gastrointestinal symptoms, neck stiffness or jolt accentuation in a patient with ALL. Undercooked beef was considered the source of C. fetus infection in this case, suggesting that the need for a neutropenic diet and safe food handling be considered.


Asunto(s)
Infecciones por Campylobacter , Campylobacter fetus/aislamiento & purificación , Ceftriaxona/administración & dosificación , Enfermedades Transmitidas por los Alimentos , Meningitis Bacterianas , Meropenem/administración & dosificación , Leucemia-Linfoma Linfoblástico de Células Precursoras , Adulto , Antibacterianos/administración & dosificación , Infecciones por Campylobacter/sangre , Infecciones por Campylobacter/líquido cefalorraquídeo , Infecciones por Campylobacter/diagnóstico , Infecciones por Campylobacter/tratamiento farmacológico , Diagnóstico Diferencial , Quimioterapia/métodos , Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos/diagnóstico , Femenino , Enfermedades Transmitidas por los Alimentos/complicaciones , Enfermedades Transmitidas por los Alimentos/diagnóstico , Enfermedades Transmitidas por los Alimentos/tratamiento farmacológico , Enfermedades Transmitidas por los Alimentos/microbiología , Humanos , Meningitis Bacterianas/diagnóstico , Meningitis Bacterianas/tratamiento farmacológico , Leucemia-Linfoma Linfoblástico de Células Precursoras/complicaciones , Leucemia-Linfoma Linfoblástico de Células Precursoras/tratamiento farmacológico , Resultado del Tratamiento
4.
Pediatr Cardiol ; 42(6): 1405-1409, 2021 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-34258648

RESUMEN

The objective of this study was to explore a new method for the differential diagnosis between fetal double aortic arch (DAA) and right aortic arch with mirror-image branches (RAA-MB). Clinical data and prenatal echocardiographic features of the DAA (n = 22) and RAA-MB (n = 65) confirmed by postnatal or autopsy findings were analyzed retrospectively. The angles between the two aortic arches in the DAA group and between the right aortic arch and the mirror branch were measured. The differences between the two groups and differential diagnosis value of the angles were compared and analyzed based on the receiver operating characteristic curve. The proportion of left-sided ductal arteriosus (100%) was higher in the DAA group than that (32.3%) in the RAA-MB group, (P < 0.05). The proportion of conotruncal anomalies is higher in the RAA-MB group (64.6%) than in the DAA group (18.2%) (P < 0.05). There was a significant difference in the angles between the groups (DAA: 50.3° ± 8.3° vs. RAA-MB: 82.9° ± 13.8°) (P < 0.01). When the cutoff value was 62.8°, the sensitivity and specificity of the differential diagnosis were 95.5% and 96.9%, respectively. Distinguishing the angle measurement between DAA and RAA-MB is helpful in prenatal prognosis. We recommend a cutoff value of 62.8°.


Asunto(s)
Aorta Torácica/diagnóstico por imagen , Síndromes del Arco Aórtico/diagnóstico , Conducto Arterial/diagnóstico por imagen , Ecocardiografía/métodos , Ultrasonografía Prenatal/métodos , Anillo Vascular/diagnóstico , Adulto , Aorta Torácica/anomalías , Diagnóstico Diferencial , Femenino , Humanos , Masculino , Embarazo , Estudios Retrospectivos , Adulto Joven
5.
Tuberk Toraks ; 69(2): 177-186, 2021 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-34256508

RESUMEN

Introduction: COVID-19 pneumonia typically presents with high fever, cough, and shortness of breath and on thorax computed tomography (CT) peripheral ground glass opacities help the diagnosis. Although typical imaging findings for COVID-19 pneumonia are specified in thorax CT, these findings can be confused with other diseases. The aim of this study is to investigate the roles of radiological imaging and laboratory findings in the differential diagnosis of COVID-19 pneumonia and acute heart failure (AHF). Materials and Methods: In the present study, 74 patients who admitted to the emergency department with respiratory distress during the pandemic period and received a diagnosis of COVID-19 pneumonia and AHF were included. Laboratory data and radiological findings of the patients, at the time of admission, were evaluated. Result: On admission, there was no difference in age, gender between two groups. However, COVID-19 exposure history was found significantly higher in COVID-19 pneumonia patients group (p<0.001). Fever, cough, and fatigue were found significantly higher in the COVID-19 pneumonia patients group (p<0.001). There was difference of lesions distribution between the two groups, centrally distributed lesions were found significantly higher in acute heart failure patients (p<0.001). Pleural effusion and cardiomegaly were found significantly higher in AHF patients (p<0.001, p<0.001). Counts of the white blood cells and lymphocytes were found significantly lower in COVID-19 pneumonia patients (p= 0.003, p= 0.009). COVID-19 pneumonia patients had significantly higher levels of CRP, ferritin, LDH and CK compared with AHF patients (p<0.001, p<0.001, p= 0.002, p= 0.013). However the level of NT-proBNP was found significantly higher in the AHF patients group (p<0.001). Conclusions: We believe that laboratory data and thorax CT findings can provide beneficial clinical information in differentiating COVID-19 pneumonia from AHF during the pandemic.


Asunto(s)
COVID-19/diagnóstico , Insuficiencia Cardíaca/diagnóstico , Pulmón/diagnóstico por imagen , Pandemias , SARS-CoV-2 , Tomografía Computarizada por Rayos X/métodos , Enfermedad Aguda , Anciano , COVID-19/epidemiología , Diagnóstico Diferencial , Femenino , Humanos , Masculino , Estudios Retrospectivos
6.
Tuberk Toraks ; 69(2): 242-246, 2021 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-34256515

RESUMEN

COVID-19, caused by severe acute respiratory syndrome coronavirus-2, typically presents with respiratory symptoms and fever, but still a variety of clinical presentations have been reported. In this study, it was aimed to report a case of COVID-19 with an atypical presentation and an atypical course. As well, the recovery phase was complicated with GBS and consequently cytomegalovirus infection. It should be kept in mind that patients with COVID-19 severe disease need to be followed for neurological and other complications which may arise during the course of critical illness.


Asunto(s)
COVID-19/diagnóstico , Síndrome de Guillain-Barré/diagnóstico , SARS-CoV-2 , Anciano , COVID-19/epidemiología , Diagnóstico Diferencial , Síndrome de Guillain-Barré/virología , Humanos , Masculino , Pandemias , Turquia/epidemiología
8.
Medicine (Baltimore) ; 100(27): e26608, 2021 Jul 09.
Artículo en Inglés | MEDLINE | ID: mdl-34232215

RESUMEN

RATIONALE: Patients preparing for surgery may have isolated, prolonged activated partial thromboplastin time (APTT). Cause analysis is warranted in patients who had neither bleeding symptom nor thromboembolic events because isolated prolongation of APTT may lead to unnecessary delayed surgical intervention or invasive procedure, even ineffective plasma infusion treatments. Here, we report a case of Hashimoto thyroiditis-associated thyroid cancer whose APTT was isolated prolonged and discuss the challenges of diagnosis and clinical management of this patient. PATIENT CONCERNS: A 57-year-old woman was admitted to the hospital due to thyroid cancer. Anticoagulant assay was performed for this patient before surgery, she had normal values for prothrombin time, thrombin time, and fibrinogen, but had isolated prolonged APTT value (20 seconds longer than normal). However, the routine laboratory of the local hospital showed normal APTT and she did not have any abnormal bleeding or thrombotic episodes. Lupus anticoagulant (LA) was strongly positive according to mixing studies and modified dilute Russell viper venom time method, it was responsible for prolonged APTT. DIAGNOSES: Hashimoto thyroiditis-associated thyroid cancer whose APTT was isolated prolonged. INTERVENTIONS: The isolated prolongation of APTT in this patient was due to LA. She had no history of anticoagulant medications and no spontaneous bleeding episodes. There should be no specific intervention before thyroidectomy. OUTCOMES: This thyroid cancer patient had an uneventful surgery and was discharged after a week. LESSONS: Prolonged APTT is not considered an absolute indication for plasma infusion therapy in patients with LA. The correct identification of the cause of APTT prolongation is essential for proper treatment of the individuals.


Asunto(s)
Manejo de la Enfermedad , Enfermedad de Hashimoto/complicaciones , Neoplasias de la Tiroides/diagnóstico , Diagnóstico Diferencial , Femenino , Enfermedad de Hashimoto/sangre , Humanos , Persona de Mediana Edad , Tiempo de Tromboplastina Parcial , Neoplasias de la Tiroides/sangre , Neoplasias de la Tiroides/etiología
9.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao ; 43(3): 309-313, 2021 Jun 30.
Artículo en Chino | MEDLINE | ID: mdl-34238404

RESUMEN

Triple-negative breast cancer is a complex type of breast cancer,the most common malignant tumor in women.Since the early image features of triple-negative breast cancer appear benign tumor with rapid growth,this cancer has progressed into the middle and late stages once diagnosed,which leads to high mortality.Therefore,the diagnosis of triple-negative breast cancer has always been a clinical difficulty.This article summarizes the role of ultrasound in the diagnosis and treatment of triple-negative breast cancer.The extracted multi-mode ultrasound features will facilitate the early detection of this cancer and improve the prognosis of these patients.


Asunto(s)
Neoplasias de la Mama , Neoplasias de la Mama Triple Negativas , Neoplasias de la Mama/diagnóstico por imagen , Diagnóstico Diferencial , Femenino , Humanos , Neoplasias de la Mama Triple Negativas/diagnóstico por imagen , Ultrasonografía , Ultrasonografía Mamaria
10.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao ; 43(3): 350-356, 2021 Jun 30.
Artículo en Chino | MEDLINE | ID: mdl-34238410

RESUMEN

Objective To compare the performance of contrast-enhanced ultrasound(CEUS)and ultrasound(US)in the differential diagnosis between cholesterol polyps and gallbladder adenomas. Methods A total of 136 patients with gallbladder polyp lesions(GPLs)and undergoing cholecystectomy in the First Medical Center of Chinese PLA General Hospital from January 2019 to October 2020 were retrospectively analyzed.All the patients underwent US and CEUS examinations before cholecystectomy.US and CEUS images of cholesterol polyps and gallbladder adenomas were compared for the evaluation of the performance of CEUS in the diagnosis of gallbladder adenomas. Results The 136 cases of GPLs included 95 cases of cholesterol polyps and 41 cases of gallbladder adenomas.Cholesterol polyps and gallbladder adenomas showed significant differences in the maximum size of GPLs( Z=-5.189, P<0.001), polyp blood flow signal(χ 2=33.630, P<0.001), vascular stalk width(Z=-7.366, P<0.001), polyp enhancement time(χ 2=22.487, P<0.001), enhancement intensity in arterial phase(χ 2=44.371, P<0.001), polyp vascular morphology(χ 2=53.814, P<0.001)and gallbladder wall integrity(χ 2=13.277, P=0.001).The sensitivity, specificity and accuracy of CEUS in distinguishing gallbladder adenomas from cholesterol polyps were 85.37%, 89.47% and 88.24%, respectively, and the area under the curve was 0.874. Conclusion CEUS can effectively distinguish gallbladder adenomas from cholesterol polyps and help patients with GPLs to select the appropriate treatment.


Asunto(s)
Adenoma , Vesícula Biliar , Adenoma/diagnóstico por imagen , Colesterol , Medios de Contraste , Diagnóstico Diferencial , Vesícula Biliar/diagnóstico por imagen , Humanos , Estudios Retrospectivos , Ultrasonografía
12.
Artículo en Inglés | MEDLINE | ID: mdl-34205104

RESUMEN

Acute febrile illnesses occur frequently in Guinea. Acute fever itself is not a unique, hallmark indication (pathognomonic sign) of any one illness or disease. In the infectious disease context, fever's underlying cause can be a wide range of viral or bacterial pathogens, including the Ebola virus. In this study, molecular and serological methods were used to analyze samples from patients hospitalized with acute febrile illness in various regions of Guinea. This analysis was undertaken with the goal of accomplishing differential diagnosis (determination of causative pathogen) in such cases. As a result, a number of pathogens, both viral and bacterial, were identified in Guinea as causative agents behind acute febrile illness. In approximately 60% of the studied samples, however, a definitive determination could not be made.


Asunto(s)
Técnicas de Laboratorio Clínico , Fiebre , Diagnóstico Diferencial , Fiebre/diagnóstico , Fiebre/etiología , Guinea/epidemiología , Humanos
13.
Emerg Med Clin North Am ; 39(3): 479-491, 2021 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-34215398

RESUMEN

The top 5 reasons for pediatric malpractice are cardiac or cardiorespiratory arrest, appendicitis, disorder of male genital organs, encephalopathy, and meningitis. Malpractice is most likely to result from an "error in diagnosis." Claims involving a "major permanent injury" were more likely to pay out money, but of all claims, only 30% result in a monetary pay out. Consideration of "high-risk misses" may help to direct a history, examination, testing, and discharge instructions.


Asunto(s)
Errores Diagnósticos/legislación & jurisprudencia , Medicina de Urgencia Pediátrica/legislación & jurisprudencia , Apendicitis/diagnóstico , Niño , Internamiento Obligatorio del Enfermo Mental/legislación & jurisprudencia , Diagnóstico Diferencial , Humanos , Consentimiento Informado/legislación & jurisprudencia , Masculino , Mala Praxis/economía , Mala Praxis/legislación & jurisprudencia , Consentimiento Paterno/legislación & jurisprudencia , Torsión del Cordón Espermático/diagnóstico , Estados Unidos
14.
Emerg Med Clin North Am ; 39(3): 589-603, 2021 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-34215404

RESUMEN

Emergency medicine clinicians are mandated reporters, legally, which obligates clinicians to report any behavior suspicious for child maltreatment to local authorities. Pediatric patients often present to the emergency department with concern for physical injury and other pervasive complaints. In some cases, these injuries are nonaccidental. To appropriately advocate and protect children from further physical and emotional trauma, it is important for clinicians to recognize the signs and symptoms of child maltreatment and sexual abuse.


Asunto(s)
Maltrato a los Niños/diagnóstico , Cuidadores , Niño , Desarrollo Infantil , Servicios de Protección Infantil , Diagnóstico Diferencial , Diagnóstico por Imagen , Medicina Legal , Humanos , Notificación Obligatoria , Anamnesis , Síndrome de Munchausen Causado por Tercero/diagnóstico , Examen Físico , Profilaxis Posexposición , Derivación y Consulta , Enfermedades de Transmisión Sexual/prevención & control , Tiempo de Tratamiento
15.
Emerg Med Clin North Am ; 39(3): 661-675, 2021 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-34215408

RESUMEN

Ear, nose, and throat (ENT) emergencies presenting with a chief complaint of pharyngitis can be due to infection, trauma, or postprocedure complications. The entities described in this article include retropharyngeal abscess, peritonsillar abscess, epiglottitis, bacterial tracheitis, and post-tonsillectomy bleeding. This article provides the emergency physician with the tools needed to decipher between the mundane and the critical, variations in presentation, and their emergent management. All of them require early recognition for any airway compromise or obstruction in order to avoid serious complications.


Asunto(s)
Epiglotitis , Absceso Peritonsilar , Absceso Retrofaríngeo , Tonsilectomía/efectos adversos , Antibacterianos/uso terapéutico , Infecciones Bacterianas/complicaciones , Infecciones Bacterianas/tratamiento farmacológico , Niño , Técnicas de Apoyo para la Decisión , Diagnóstico Diferencial , Drenaje , Epiglotitis/diagnóstico , Epiglotitis/terapia , Humanos , Medicina de Urgencia Pediátrica , Absceso Peritonsilar/diagnóstico , Absceso Peritonsilar/terapia , Hemorragia Posoperatoria/etiología , Hemorragia Posoperatoria/terapia , Absceso Retrofaríngeo/diagnóstico , Absceso Retrofaríngeo/terapia , Traqueítis/diagnóstico , Traqueítis/terapia
16.
S D Med ; 74(3): 121-126, 2021 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-34232591

RESUMEN

Lupus erythematosus (LE) is a complex autoimmune disease that presents with a wide variety of clinical and immunopathological features, making it challenging to reach a correct and prompt diagnosis. Patients with LE most frequently present with cutaneous and rheumatologic manifestations. As cutaneous findings may be the first sign of disease, their timely recognition is important for proper workup and management of LE. Here we present a case of subacute cutaneous lupus erythematosus (SCLE) and review the cutaneous manifestations of lupus erythematosus and the histopathological correlates to raise awareness and promote faster times to diagnosis and treatment.


Asunto(s)
Lupus Eritematoso Cutáneo , Lupus Eritematoso Sistémico , Diagnóstico Diferencial , Humanos , Lupus Eritematoso Cutáneo/diagnóstico , Lupus Eritematoso Sistémico/diagnóstico , Piel
17.
Comput Math Methods Med ; 2021: 5528144, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34194535

RESUMEN

Pneumonia is an infamous life-threatening lung bacterial or viral infection. The latest viral infection endangering the lives of many people worldwide is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes COVID-19. This paper is aimed at detecting and differentiating viral pneumonia and COVID-19 disease using digital X-ray images. The current practices include tedious conventional processes that solely rely on the radiologist or medical consultant's technical expertise that are limited, time-consuming, inefficient, and outdated. The implementation is easily prone to human errors of being misdiagnosed. The development of deep learning and technology improvement allows medical scientists and researchers to venture into various neural networks and algorithms to develop applications, tools, and instruments that can further support medical radiologists. This paper presents an overview of deep learning techniques made in the chest radiography on COVID-19 and pneumonia cases.


Asunto(s)
Prueba de COVID-19/métodos , COVID-19/diagnóstico por imagen , Aprendizaje Profundo , SARS-CoV-2 , Algoritmos , COVID-19/diagnóstico , Prueba de COVID-19/estadística & datos numéricos , Biología Computacional , Diagnóstico Diferencial , Humanos , Conceptos Matemáticos , Redes Neurales de la Computación , Neumonía Viral/diagnóstico , Neumonía Viral/diagnóstico por imagen , Radiografía Torácica/estadística & datos numéricos , Tomografía Computarizada por Rayos X/estadística & datos numéricos
18.
J Radiol Case Rep ; 15(3): 9-18, 2021 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-34267866

RESUMEN

Schwannomas of the prostate are a rare entity and usually diagnosed incidentally following surgical management of presumed benign prostate hyperplasia or prostate adenocarcinoma. We present a case of sporadic periprostatic schwannoma diagnosed in conjunction with multifocal prostate adenocarcinoma on pre-operative multiparametric magnetic resonance imaging.


Asunto(s)
Adenocarcinoma/diagnóstico , Neurilemoma/diagnóstico , Neoplasias de la Próstata/diagnóstico , Adenocarcinoma/diagnóstico por imagen , Anciano , Diagnóstico Diferencial , Humanos , Linfadenopatía/diagnóstico , Imagen por Resonancia Magnética , Masculino , Neurilemoma/diagnóstico por imagen , Neoplasias de la Próstata/diagnóstico por imagen
19.
Indian J Dent Res ; 32(1): 120-123, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34269249

RESUMEN

Accidental detection of asymptomatic clinically suspicious lesions is a common occurrence in routine clinical examination of the oral cavity. In certain cases, these lesions may mimic benign lesions further adding to confusion. In this case report, we have discussed the case of a 51-year-old male patient with an asymptomatic palatal mass which was detected during a routine dental check-up and subsequently confirmed to be an adenoid cystic carcinoma (ACC) arising from the minor salivary glands. The patient underwent right partial maxillectomy followed by radiation therapy and has been disease-free for 6 years and is on follow-up. ACC is a malignant tumour of the salivary glands commonly occurring in the palate, characterized by a slow indolent growth phase, with a high predilection for late recurrences which can be local or systemic. This article describes the importance of recognizing this clinical entity as a differential diagnosis in the evaluation of asymptomatic palatal lesions to enable early diagnosis and institution of appropriate treatment to successfully treat the disease.


Asunto(s)
Carcinoma Adenoide Quístico , Neoplasias de las Glándulas Salivales , Carcinoma Adenoide Quístico/diagnóstico , Diagnóstico Diferencial , Humanos , Masculino , Persona de Mediana Edad , Paladar (Hueso) , Neoplasias de las Glándulas Salivales/diagnóstico , Glándulas Salivales Menores
20.
BMJ Case Rep ; 14(7)2021 Jul 02.
Artículo en Inglés | MEDLINE | ID: mdl-34215640

RESUMEN

An 82-year-old man presented with a right scalp lesion which had been increasing in size. The patient's medical history was significant for a heart transplant 25 years before, and he was on chronic immunosuppression. Biopsy of the lesion showed atypical fibroxanthoma. The patient underwent an excision of the lesion with split thickness skin graft. Pathology showed fibroxanthoma with negative margins. Over the next 9 months, the patient developed new lesions, which were also excised to negative margins. However, with each new lesion, the histology demonstrated increasing dysplasia and ultimately pleomorphic sarcoma. The patient had a metastatic workup with CT of the chest, which was negative, and he underwent a radical scalpectomy, split thickness skin graft placement and adjuvant radiation therapy. The patient has not developed any new scalp lesions and no evidence of metastasis.


Asunto(s)
Trasplante de Corazón , Sarcoma , Neoplasias Cutáneas , Anciano de 80 o más Años , Biopsia , Diagnóstico Diferencial , Humanos , Masculino , Sarcoma/diagnóstico , Neoplasias Cutáneas/diagnóstico
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